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The map label for this gene is cobI [H]

Identifier: 146341785

GI number: 146341785

Start: 5103314

End: 5104072

Strand: Reverse

Name: cobI [H]

Synonym: BRADO4904

Alternate gene names: 146341785

Gene position: 5104072-5103314 (Counterclockwise)

Preceding gene: 146341786

Following gene: 146341784

Centisome position: 68.45

GC content: 67.46

Gene sequence:

>759_bases
ATGAGTCTGCTGGAGACCATCGCCGGTCGAGCTGAGGCCGGGACGCTCTACGGCATCGGGGTGGGGCCCGGCGATGTGCG
CTATCTGACGCTGCGCGCGGCCGGACTGATCCAGTCGGTCGACGTGATCGCCTTCTTCGCCAAGCGCGGCATGGAGGGCA
ACGCACGGCGGATCGTCGCGCCGCTGATGCGGGCCGGCCGCCAGGAGCTACGGCTGGAATATCCGGTCACCGAGGAGGTG
CCTGTCGCCGACGCGTCCTATCAAGCGCAGATCGGCAATTTCTATCAGCGGGCCGCCGGCAGCATCGCAGCGCATCTGGC
CGCCGGGCGATCGGTCGGCCTGCTGTCCGAAGGCGATCCCTTCTTCTATGGCTCGTTCATGCATATGTGGCGGCGCCTCG
AGCAGGATCATCCGGTCGAGGTCGTTCCCGGCGTCACGGGCATGTCCGGCTGCTGGACCAAGGCTAACGTGCCGATCACC
TGGGGCGACGACATCCTGTCGGTGCTCCCGGGGACGTTGCCCGAGGATGTCCTGCAGGATCGGCTGACGCGCTGCGAGGC
CGCTGTCATCATGAAGGTCGGGCGCAATCTCGCCAAGGCGAAGCGTGCGATCGCGCAGGCCGGACTGCTTGGTCGCGCGC
TCTACGTCGAACGCGGCACGATGGAGGCGCAACGCGTCGCGCCGCTGGCCGAGGTCGAGCAGGACCGCGGTCCGTATTTC
TCGATGATCCTGATCCCCGGACAAGGGCGCCGGCTGTGA

Upstream 100 bases:

>100_bases
TCGCGGCCGACGGCCGGGTGCCGTACCTGATCGTGAAGGGGCGCAAGGGCGGCAGCGCCATGGCCGTCGCGGCCGTCAAT
GCGATCGCGAGCGACGTTGA

Downstream 100 bases:

>100_bases
CGGGCACGCTCACCATCGTCGGCGTCGGCCCCGGCGCGTCCGAGCTGATCACGCCGGCGGCGTCGGCCGTGATCGCAAGG
GCGACTGATCTGATCGGCTA

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSLLETIAGRAEAGTLYGIGVGPGDVRYLTLRAAGLIQSVDVIAFFAKRGMEGNARRIVAPLMRAGRQELRLEYPVTEEV
PVADASYQAQIGNFYQRAAGSIAAHLAAGRSVGLLSEGDPFFYGSFMHMWRRLEQDHPVEVVPGVTGMSGCWTKANVPIT
WGDDILSVLPGTLPEDVLQDRLTRCEAAVIMKVGRNLAKAKRAIAQAGLLGRALYVERGTMEAQRVAPLAEVEQDRGPYF
SMILIPGQGRRL

Sequences:

>Translated_252_residues
MSLLETIAGRAEAGTLYGIGVGPGDVRYLTLRAAGLIQSVDVIAFFAKRGMEGNARRIVAPLMRAGRQELRLEYPVTEEV
PVADASYQAQIGNFYQRAAGSIAAHLAAGRSVGLLSEGDPFFYGSFMHMWRRLEQDHPVEVVPGVTGMSGCWTKANVPIT
WGDDILSVLPGTLPEDVLQDRLTRCEAAVIMKVGRNLAKAKRAIAQAGLLGRALYVERGTMEAQRVAPLAEVEQDRGPYF
SMILIPGQGRRL
>Mature_251_residues
SLLETIAGRAEAGTLYGIGVGPGDVRYLTLRAAGLIQSVDVIAFFAKRGMEGNARRIVAPLMRAGRQELRLEYPVTEEVP
VADASYQAQIGNFYQRAAGSIAAHLAAGRSVGLLSEGDPFFYGSFMHMWRRLEQDHPVEVVPGVTGMSGCWTKANVPITW
GDDILSVLPGTLPEDVLQDRLTRCEAAVIMKVGRNLAKAKRAIAQAGLLGRALYVERGTMEAQRVAPLAEVEQDRGPYFS
MILIPGQGRRL

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27354; Mature: 27223

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLETIAGRAEAGTLYGIGVGPGDVRYLTLRAAGLIQSVDVIAFFAKRGMEGNARRIVA
CCHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PLMRAGRQELRLEYPVTEEVPVADASYQAQIGNFYQRAAGSIAAHLAAGRSVGLLSEGDP
HHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FFYGSFMHMWRRLEQDHPVEVVPGVTGMSGCWTKANVPITWGDDILSVLPGTLPEDVLQD
CEEHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEECHHHHHHCCCCCCHHHHHH
RLTRCEAAVIMKVGRNLAKAKRAIAQAGLLGRALYVERGTMEAQRVAPLAEVEQDRGPYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCHHHHHHHCCCCEE
SMILIPGQGRRL
EEEEECCCCCCC
>Mature Secondary Structure 
SLLETIAGRAEAGTLYGIGVGPGDVRYLTLRAAGLIQSVDVIAFFAKRGMEGNARRIVA
CHHHHHCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PLMRAGRQELRLEYPVTEEVPVADASYQAQIGNFYQRAAGSIAAHLAAGRSVGLLSEGDP
HHHHCCHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FFYGSFMHMWRRLEQDHPVEVVPGVTGMSGCWTKANVPITWGDDILSVLPGTLPEDVLQD
CEEHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEECHHHHHHCCCCCCHHHHHH
RLTRCEAAVIMKVGRNLAKAKRAIAQAGLLGRALYVERGTMEAQRVAPLAEVEQDRGPYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCHHHHHHHCCCCEE
SMILIPGQGRRL
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]