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The map label for this gene is yccK [H]

Identifier: 146340930

GI number: 146340930

Start: 4192601

End: 4193596

Strand: Direct

Name: yccK [H]

Synonym: BRADO4001

Alternate gene names: 146340930

Gene position: 4192601-4193596 (Clockwise)

Preceding gene: 146340927

Following gene: 146340932

Centisome position: 56.23

GC content: 64.66

Gene sequence:

>996_bases
ATGAAGACGAGAACCCTGGGCAAAAGTGGTCTCGAGGTGTCGGCCATCGGCTTCGGCTGCATGGGCCTGAACTTCGGCTA
CGGTCATGCGCTCGCGAAAGAGGATGCGGTCGATCTCATCCGCGCCGCCTTCGACCGCGGCGTGACGTTTTTCGACACGG
CCGAAATTTATGGACCGTTCACGAACGAGGAGCTGGTCGGCGACGCCCTGGCTCCCGTCCGGGACAAGGTGGTCATCGCC
ACCAAATTCGGCTTCGCGATCGACCCGGCGACCGGCAGGTCCTCAGGGATGAACAGCCGCCCCGAGCGAATTCGCGCGGT
CGCGGATGCATCCCTGAAGCGGCTGAAGACCGATCGCATCGATCTGTTCTATCAGCACCGCGTCGATCCGGACGTGCCGA
TCGAGGACGTCGCCGGCGCGGTCAAGGATCTCATCGGGCAAGGCAAGGTCAGGTACTTCGGCCTGTCCGAGCCCGGCGCC
CAGACCGTCCGACGCGCGCATGCGGTGCAGCCCGTGACCGCGCTCCAGAACGAATATTCACTCTGGACCCGGGGTCCAGA
GAGCAACGGCATCATGCAGGCCTGCGAGGAACTCGGCATCGGCCTGGTGCCCTACAGTCCGCTGGGAAAGGGATTTCTGA
CCGGCGCGATGAACGAGACCACCAGGCTGCCCGACAACGACTTCCGCAGCACCCTGCCGCGCTTTACGCCCGCGGCGATG
AAGGCCAACCAGGCGCTGGTCGATCTCCTCAAACGAATCGCCGAACGCAGGGCATCCACGCCGGCCCAGATCGCGCTCGC
CTGGCTGCTCGCGCAGAAGCCATGGATCGTTCCCATTCCAGGCACGACCAAGCTCCATCGCCTAGAGGAGAATCTCAAGG
CCGCCGACGTCGAGCTCACGGGGGACGATCTCGCCCAGATTGAGCAGGCTGCGGCCGCGATCAAGGTCGAAGGCGAACGC
TATCCGCCTCACCTGATGGCCACGACGGGGCGCTGA

Upstream 100 bases:

>100_bases
CATCTAATGTCATCGTAGTCACAGCCTTAGGTTCAGTCTGGACGGAGAGGTCGACGATGCGCGGTGCCGGCGTCGACCGG
AAGAGAGAGAGGAGACCGGG

Downstream 100 bases:

>100_bases
CGCGCTTCACCAAAACGGCCGGGCGCTCCGTGAGCGCCCGAAGCCACTCCTCGTCAACGCACGATCGACAGCGCGTCGCC
TGCAGCTTCACGGACATTTC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKTRTLGKSGLEVSAIGFGCMGLNFGYGHALAKEDAVDLIRAAFDRGVTFFDTAEIYGPFTNEELVGDALAPVRDKVVIA
TKFGFAIDPATGRSSGMNSRPERIRAVADASLKRLKTDRIDLFYQHRVDPDVPIEDVAGAVKDLIGQGKVRYFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPESNGIMQACEELGIGLVPYSPLGKGFLTGAMNETTRLPDNDFRSTLPRFTPAAM
KANQALVDLLKRIAERRASTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLKAADVELTGDDLAQIEQAAAAIKVEGER
YPPHLMATTGR

Sequences:

>Translated_331_residues
MKTRTLGKSGLEVSAIGFGCMGLNFGYGHALAKEDAVDLIRAAFDRGVTFFDTAEIYGPFTNEELVGDALAPVRDKVVIA
TKFGFAIDPATGRSSGMNSRPERIRAVADASLKRLKTDRIDLFYQHRVDPDVPIEDVAGAVKDLIGQGKVRYFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPESNGIMQACEELGIGLVPYSPLGKGFLTGAMNETTRLPDNDFRSTLPRFTPAAM
KANQALVDLLKRIAERRASTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLKAADVELTGDDLAQIEQAAAAIKVEGER
YPPHLMATTGR
>Mature_331_residues
MKTRTLGKSGLEVSAIGFGCMGLNFGYGHALAKEDAVDLIRAAFDRGVTFFDTAEIYGPFTNEELVGDALAPVRDKVVIA
TKFGFAIDPATGRSSGMNSRPERIRAVADASLKRLKTDRIDLFYQHRVDPDVPIEDVAGAVKDLIGQGKVRYFGLSEPGA
QTVRRAHAVQPVTALQNEYSLWTRGPESNGIMQACEELGIGLVPYSPLGKGFLTGAMNETTRLPDNDFRSTLPRFTPAAM
KANQALVDLLKRIAERRASTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLKAADVELTGDDLAQIEQAAAAIKVEGER
YPPHLMATTGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=29.4117647058824, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=30, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436969, Length=321, Percent_Identity=29.2834890965732, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4504825, Length=318, Percent_Identity=29.2452830188679, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=29.6774193548387, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=29.6774193548387, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI223718702, Length=287, Percent_Identity=28.9198606271777, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41152114, Length=287, Percent_Identity=28.9198606271777, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI41327764, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=32.4242424242424, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=33.0246913580247, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=27.6470588235294, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=30.3468208092486, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787674, Length=325, Percent_Identity=27.3846153846154, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788081, Length=281, Percent_Identity=25.2669039145907, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994888, Length=294, Percent_Identity=29.2517006802721, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17566692, Length=318, Percent_Identity=24.8427672955975, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325384, Length=300, Percent_Identity=30.3333333333333, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=27.0588235294118, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=327, Percent_Identity=27.5229357798165, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=27.7027027027027, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=297, Percent_Identity=28.2828282828283, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=249, Percent_Identity=27.710843373494, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=24.1590214067278, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=24.3827160493827, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=26.9911504424779, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646155, Length=162, Percent_Identity=32.0987654320988, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35970; Mature: 35970

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRTLGKSGLEVSAIGFGCMGLNFGYGHALAKEDAVDLIRAAFDRGVTFFDTAEIYGPF
CCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCC
TNEELVGDALAPVRDKVVIATKFGFAIDPATGRSSGMNSRPERIRAVADASLKRLKTDRI
CCHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPDVPIEDVAGAVKDLIGQGKVRYFGLSEPGAQTVRRAHAVQPVTALQNEYS
HEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCH
LWTRGPESNGIMQACEELGIGLVPYSPLGKGFLTGAMNETTRLPDNDFRSTLPRFTPAAM
HEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCCHHHH
KANQALVDLLKRIAERRASTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLKAADVELT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEC
GDDLAQIEQAAAAIKVEGERYPPHLMATTGR
CHHHHHHHHHHHEEEECCCCCCCCEEEECCC
>Mature Secondary Structure
MKTRTLGKSGLEVSAIGFGCMGLNFGYGHALAKEDAVDLIRAAFDRGVTFFDTAEIYGPF
CCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCC
TNEELVGDALAPVRDKVVIATKFGFAIDPATGRSSGMNSRPERIRAVADASLKRLKTDRI
CCHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPDVPIEDVAGAVKDLIGQGKVRYFGLSEPGAQTVRRAHAVQPVTALQNEYS
HEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHCCCH
LWTRGPESNGIMQACEELGIGLVPYSPLGKGFLTGAMNETTRLPDNDFRSTLPRFTPAAM
HEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCCHHHH
KANQALVDLLKRIAERRASTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENLKAADVELT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEC
GDDLAQIEQAAAAIKVEGERYPPHLMATTGR
CHHHHHHHHHHHEEEECCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]