Click here to switch to the map view.

The map label for this gene is dacC [H]

Identifier: 146340768

GI number: 146340768

Start: 3996470

End: 3997624

Strand: Direct

Name: dacC [H]

Synonym: BRADO3826

Alternate gene names: 146340768

Gene position: 3996470-3997624 (Clockwise)

Preceding gene: 146340766

Following gene: 146340769

Centisome position: 53.6

GC content: 64.16

Gene sequence:

>1155_bases
ATGCTCTACGCCGCCAACCAGAGCGTCCAAGGCGCGAAGAAAGACGATGGCGGCTTCGATGGCGATGCACCGACCGCGAT
CCTCGTTGAAGCGACCAGCGGCAGCGTGCTGTTCGAGAAGAACGCCGACGAGTTGCGCGCGCCCTCCAGCATGATGAAAC
TGATGACCGCCGAGGTGGTGTTCAACGCCGTCAAGGAGGGCACGGTCAAGCTCAACGACGAATACCGGATCAGCGAGAAC
GCGTGGCGCAAGGGCGGGGCGCCGTCCGGCACCTCGACGATGTTCGCCGCGCTGAACAGCAAGGTCCCGGTCAGCGACCT
CCTGCATGGCGCGATCATCCAGAGCGGCAACGATGCCTGCATCGCGCTCGCCGAGGGCATGGCTGGCAACGAGAAGATCT
TTGCCGCGGACTACATGACCAAGCGCGCCCGCGAGCTTGGCCTGTCCAAATCGACCTTCGCCAATTCCAACGGCTTGCCG
GATCCCGGCAACAAGATGACGGTGCGCGAGCTGTCGATGCTGGCGCGCCACATCATCCTGGATTTCCCGGAGTTCTATAA
GATCTTCGGCGAGAAGGAATTCACCTGGAACAAGATCCGCCAGCAGAACCGCAATCCATTGCTGAACGCGATGGAAGGCG
CGGACGGGCTGAAGACCGGCTACACCAAGGAGGGCGGCTACGGCATGGTCGGCTCCGCCGTGCAGAACGGCACGCGCTTG
ATCGTCGTCGTCAACGGCCTGGAGGATCCCGAGGACCGCGCCACCGAGGCCAAGAAGATGCTGGAATGGGGCTTCCGCAA
CTTCGAGACCCGCACCCTTTTCGCGGCCGACCAGACGCTCGGCTACGCCAAAGTATTCGGTGGCGAGAGCCGCTCGGTGA
AGCTGTCGAGCCCGGTGCCGGTCAAAGTGATGGTGCAGAAGAACGGCGGCGAGAAGCTGCTCGCGCGCATCATCTATAGC
GGCCCGGTCAAGGCGCCGGTCGAGGCCGGGCAGAAGGTCGGGGTTGTCAGGGTTTGGCGCGGCCCCAATATCGCCATGGA
GGCCCCCGTCTATGCCGGCGAGGCAGTGGGCATGGGGTCCACGATGCGGCGCGCGATCGATGGGGCCAGCGAGCTCGTGA
TCGGAATGTTCCGCGCCGGGGCCGAGAAGCTCTGA

Upstream 100 bases:

>100_bases
TTTCATGACCTCACCGTTCCGCCGCTCCGGTTTCACGACCGGATGGACGGCGCGCGCGCTCCTTGTCGTGACGGCGGCGT
TGGTGATCGGCTGGAGCGGG

Downstream 100 bases:

>100_bases
AGACATGGCGGATGCAGCTTTGAAACGTGGTCCTGGCCGCGGCCGGTTCGTCACCTTCGAGGGCGGCGAGGGCGCCGGAA
AATCCACGCAGATCAAGATG

Product: putative Serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLYAANQSVQGAKKDDGGFDGDAPTAILVEATSGSVLFEKNADELRAPSSMMKLMTAEVVFNAVKEGTVKLNDEYRISEN
AWRKGGAPSGTSTMFAALNSKVPVSDLLHGAIIQSGNDACIALAEGMAGNEKIFAADYMTKRARELGLSKSTFANSNGLP
DPGNKMTVRELSMLARHIILDFPEFYKIFGEKEFTWNKIRQQNRNPLLNAMEGADGLKTGYTKEGGYGMVGSAVQNGTRL
IVVVNGLEDPEDRATEAKKMLEWGFRNFETRTLFAADQTLGYAKVFGGESRSVKLSSPVPVKVMVQKNGGEKLLARIIYS
GPVKAPVEAGQKVGVVRVWRGPNIAMEAPVYAGEAVGMGSTMRRAIDGASELVIGMFRAGAEKL

Sequences:

>Translated_384_residues
MLYAANQSVQGAKKDDGGFDGDAPTAILVEATSGSVLFEKNADELRAPSSMMKLMTAEVVFNAVKEGTVKLNDEYRISEN
AWRKGGAPSGTSTMFAALNSKVPVSDLLHGAIIQSGNDACIALAEGMAGNEKIFAADYMTKRARELGLSKSTFANSNGLP
DPGNKMTVRELSMLARHIILDFPEFYKIFGEKEFTWNKIRQQNRNPLLNAMEGADGLKTGYTKEGGYGMVGSAVQNGTRL
IVVVNGLEDPEDRATEAKKMLEWGFRNFETRTLFAADQTLGYAKVFGGESRSVKLSSPVPVKVMVQKNGGEKLLARIIYS
GPVKAPVEAGQKVGVVRVWRGPNIAMEAPVYAGEAVGMGSTMRRAIDGASELVIGMFRAGAEKL
>Mature_384_residues
MLYAANQSVQGAKKDDGGFDGDAPTAILVEATSGSVLFEKNADELRAPSSMMKLMTAEVVFNAVKEGTVKLNDEYRISEN
AWRKGGAPSGTSTMFAALNSKVPVSDLLHGAIIQSGNDACIALAEGMAGNEKIFAADYMTKRARELGLSKSTFANSNGLP
DPGNKMTVRELSMLARHIILDFPEFYKIFGEKEFTWNKIRQQNRNPLLNAMEGADGLKTGYTKEGGYGMVGSAVQNGTRL
IVVVNGLEDPEDRATEAKKMLEWGFRNFETRTLFAADQTLGYAKVFGGESRSVKLSSPVPVKVMVQKNGGEKLLARIIYS
GPVKAPVEAGQKVGVVRVWRGPNIAMEAPVYAGEAVGMGSTMRRAIDGASELVIGMFRAGAEKL

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=368, Percent_Identity=39.4021739130435, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI87082022, Length=348, Percent_Identity=34.4827586206897, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786851, Length=350, Percent_Identity=35.4285714285714, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41322; Mature: 41322

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYAANQSVQGAKKDDGGFDGDAPTAILVEATSGSVLFEKNADELRAPSSMMKLMTAEVV
CEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHHHHCCHHHHHHHHHHHH
FNAVKEGTVKLNDEYRISENAWRKGGAPSGTSTMFAALNSKVPVSDLLHGAIIQSGNDAC
HHHHHCCEEEECCCEEECCHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEE
IALAEGMAGNEKIFAADYMTKRARELGLSKSTFANSNGLPDPGNKMTVRELSMLARHIIL
EEEECCCCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DFPEFYKIFGEKEFTWNKIRQQNRNPLLNAMEGADGLKTGYTKEGGYGMVGSAVQNGTRL
CCHHHHHHHCCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCEE
IVVVNGLEDPEDRATEAKKMLEWGFRNFETRTLFAADQTLGYAKVFGGESRSVKLSSPVP
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEECCCCC
VKVMVQKNGGEKLLARIIYSGPVKAPVEAGQKVGVVRVWRGPNIAMEAPVYAGEAVGMGS
EEEEEECCCCHHHHHHHHHCCCCCCHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCH
TMRRAIDGASELVIGMFRAGAEKL
HHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLYAANQSVQGAKKDDGGFDGDAPTAILVEATSGSVLFEKNADELRAPSSMMKLMTAEVV
CEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCHHHHHCCHHHHHHHHHHHH
FNAVKEGTVKLNDEYRISENAWRKGGAPSGTSTMFAALNSKVPVSDLLHGAIIQSGNDAC
HHHHHCCEEEECCCEEECCHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEE
IALAEGMAGNEKIFAADYMTKRARELGLSKSTFANSNGLPDPGNKMTVRELSMLARHIIL
EEEECCCCCCCEEEEHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DFPEFYKIFGEKEFTWNKIRQQNRNPLLNAMEGADGLKTGYTKEGGYGMVGSAVQNGTRL
CCHHHHHHHCCCCCCHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCEE
IVVVNGLEDPEDRATEAKKMLEWGFRNFETRTLFAADQTLGYAKVFGGESRSVKLSSPVP
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCEEEECCCCC
VKVMVQKNGGEKLLARIIYSGPVKAPVEAGQKVGVVRVWRGPNIAMEAPVYAGEAVGMGS
EEEEEECCCCHHHHHHHHHCCCCCCHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCH
TMRRAIDGASELVIGMFRAGAEKL
HHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]