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The map label for this gene is pheC [H]

Identifier: 146340753

GI number: 146340753

Start: 3980235

End: 3981056

Strand: Reverse

Name: pheC [H]

Synonym: BRADO3810

Alternate gene names: 146340753

Gene position: 3981056-3980235 (Counterclockwise)

Preceding gene: 146340755

Following gene: 146340752

Centisome position: 53.39

GC content: 63.87

Gene sequence:

>822_bases
ATGCGGCCCAACCGAACGAGGTATTTCAATATGGGATTTTTCAACCGGACGATCGCCACCTTGAGCGCGGTTGCGCTGGT
CTGCGGGCTCGCCGCGCAGGCGCTGGCGGATCAGGCCTCGCGCCTCGACGAGATCATGCAGCGCGGTGCCCTGCGCGTCG
GCATGACCGGCGACTACAAGCCGTTCACCTACCTGGACAAGGCCACCGGCAAGTTCTCCGGCTTCGACGTCGACATGGCC
GAGGCGCTCGGCAAGGCGATGGGCGTCAAGGTCGAGTTCGTGCCGACCAGCTGGCCGCAGCTGATGAAGGATTTCGAGGC
CGACAAGTTCGACGTCGCGATGGGCGGCGTGTCGATCACGCTCGACCGCCAGAAGAAGGGCTTCTTCTCGACGCCGATCA
TGCGCGAGGGCAAGACCCCGATCGCCCGCTGCAGCGACACCGGCAAGTACCAGACGCTCGCCGATATCGACAGACCGGGC
ACCCGTGTGGTCGTCAACCCCGGCGGCACCAACGAGCGTTTCGCCCGCGCCAACATCAAGGCGGCCGACATCCGCGTCCA
CCCCGACAACGTCACGATCTTCGACGAGATCGCCAAGGGTGACGCCGACCTGATGATGACCGATGCCTCCGAAACCCGCT
ACCAGCAGAAGCTGCATCCCGGCGTGCTTTGCGCCGTCCATCCCGACAAGCCGTTCGACTTCTCCGAGAAGGCCTATTGG
CTGCAGCGTGACGTCGCGCTGAAGGCGTTCGTCGACCAGTGGCTGCACATGTCGACCGAAAATGGCAGCTACCAGGCGAT
CTACAAGACCTGGTTCGACTGA

Upstream 100 bases:

>100_bases
CCGATGCCTCACTGATCGATATGCCCACGGATCCGACCTCGCTGTTGGTAAGCTGCCCTGCGCCACCCCTCGTCGGGCGC
GCTGACGTCGGCTAAGACTA

Downstream 100 bases:

>100_bases
CGAACGACCTCATCCTCCGCGGTCCGGCTGATGCGCTGGACCGCGACCGAACACCCTAGCGGCAGTGCTTCGACGGACCG
CGGAAGCAGTCAGCGGTTGA

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRPNRTRYFNMGFFNRTIATLSAVALVCGLAAQALADQASRLDEIMQRGALRVGMTGDYKPFTYLDKATGKFSGFDVDMA
EALGKAMGVKVEFVPTSWPQLMKDFEADKFDVAMGGVSITLDRQKKGFFSTPIMREGKTPIARCSDTGKYQTLADIDRPG
TRVVVNPGGTNERFARANIKAADIRVHPDNVTIFDEIAKGDADLMMTDASETRYQQKLHPGVLCAVHPDKPFDFSEKAYW
LQRDVALKAFVDQWLHMSTENGSYQAIYKTWFD

Sequences:

>Translated_273_residues
MRPNRTRYFNMGFFNRTIATLSAVALVCGLAAQALADQASRLDEIMQRGALRVGMTGDYKPFTYLDKATGKFSGFDVDMA
EALGKAMGVKVEFVPTSWPQLMKDFEADKFDVAMGGVSITLDRQKKGFFSTPIMREGKTPIARCSDTGKYQTLADIDRPG
TRVVVNPGGTNERFARANIKAADIRVHPDNVTIFDEIAKGDADLMMTDASETRYQQKLHPGVLCAVHPDKPFDFSEKAYW
LQRDVALKAFVDQWLHMSTENGSYQAIYKTWFD
>Mature_273_residues
MRPNRTRYFNMGFFNRTIATLSAVALVCGLAAQALADQASRLDEIMQRGALRVGMTGDYKPFTYLDKATGKFSGFDVDMA
EALGKAMGVKVEFVPTSWPQLMKDFEADKFDVAMGGVSITLDRQKKGFFSTPIMREGKTPIARCSDTGKYQTLADIDRPG
TRVVVNPGGTNERFARANIKAADIRVHPDNVTIFDEIAKGDADLMMTDASETRYQQKLHPGVLCAVHPDKPFDFSEKAYW
LQRDVALKAFVDQWLHMSTENGSYQAIYKTWFD

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=252, Percent_Identity=29.7619047619048, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787031, Length=215, Percent_Identity=27.906976744186, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787085, Length=239, Percent_Identity=25.1046025104602, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788649, Length=269, Percent_Identity=26.3940520446097, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 30540; Mature: 30540

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPNRTRYFNMGFFNRTIATLSAVALVCGLAAQALADQASRLDEIMQRGALRVGMTGDYK
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
PFTYLDKATGKFSGFDVDMAEALGKAMGVKVEFVPTSWPQLMKDFEADKFDVAMGGVSIT
CCEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEEECCEEEE
LDRQKKGFFSTPIMREGKTPIARCSDTGKYQTLADIDRPGTRVVVNPGGTNERFARANIK
EECCCCCCCCCCCCCCCCCCCEECCCCCCEEEHHHCCCCCCEEEECCCCCCCCEEECCCE
AADIRVHPDNVTIFDEIAKGDADLMMTDASETRYQQKLHPGVLCAVHPDKPFDFSEKAYW
EEEEEECCCCEEEEHHHHCCCCCEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHH
LQRDVALKAFVDQWLHMSTENGSYQAIYKTWFD
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MRPNRTRYFNMGFFNRTIATLSAVALVCGLAAQALADQASRLDEIMQRGALRVGMTGDYK
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
PFTYLDKATGKFSGFDVDMAEALGKAMGVKVEFVPTSWPQLMKDFEADKFDVAMGGVSIT
CCEEEECCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEEECCEEEE
LDRQKKGFFSTPIMREGKTPIARCSDTGKYQTLADIDRPGTRVVVNPGGTNERFARANIK
EECCCCCCCCCCCCCCCCCCCEECCCCCCEEEHHHCCCCCCEEEECCCCCCCCEEECCCE
AADIRVHPDNVTIFDEIAKGDADLMMTDASETRYQQKLHPGVLCAVHPDKPFDFSEKAYW
EEEEEECCCCEEEEHHHHCCCCCEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHH
LQRDVALKAFVDQWLHMSTENGSYQAIYKTWFD
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]