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The map label for this gene is fusA [H]

Identifier: 146340749

GI number: 146340749

Start: 3976161

End: 3978182

Strand: Direct

Name: fusA [H]

Synonym: BRADO3806

Alternate gene names: 146340749

Gene position: 3976161-3978182 (Clockwise)

Preceding gene: 146340748

Following gene: 146340754

Centisome position: 53.32

GC content: 69.24

Gene sequence:

>2022_bases
ATGGCGCATGTCGACGCCGGCAAGACCACCTTGACCGAGCGCATCCTGCTCGACACCGGCAAGATCCATCAGGCCGGCGA
CGTTCACACCGGCAACACCGAGACCGACTCCCATGCACTCGAGAAGAAGCATGGGATCACGATCTCGGCGGCGGCGATCT
CGTGCGAATGGCGTGATGCGTTCATCACCATCATCGACACGCCCGGCCATGTCGATTTCCAGATCGAGGTCGAGCGCTCA
CTGCGCGTGCTCGACGGCGCGATCGCCGTGTTCTCGGCGGTCTCCGGCGTCGAGCCGCAGTCGGAAACGGTCTGGCGACA
GGCCGACCGGCTCGGCGTGCCGCGGCTGTGCTTCGTCAACAAGATGGACCAGGTCGGAGCCGATCTGCAGCGGACGGTCG
AGATGATCGCCGATCGTCTCGGCGCCACGCCGCTCGTCCTGCAACTGCCGCTTCGAGGCGAGGACGGCTTCGCCGGCGTG
GTCGACCTCGTGGCGATGAAGGCGTTGTACTGGGATGGAGCGCAGCCGCAGCCATCGGCCGGCGCCATCCCGGAAGAGCT
GCGCAGCGCGGCCGAGCGACAGCGACAGCGTCTGCTGGAGACGCTGGCGGATCAGGACGCGGCGATCATGGCGGCCTATG
TCGGCGGTGAGACGATCAGCGCGGCTGACCTCAAGGCGGCGATCCGCAGGGCGTGCCTCGCGGGACGGCTTACGCCTGTG
CTGTGCGGCTCGGCCTACCGGAACGTCGGCGTGCATCCGCTGCTCGACGCCATCGTCGACTACGCGCCGGGTCCGGAGGA
CCGGCCGGCGGTCGCGGGGCTAGACCCGCGCAGCGGCGCGGCCGAGCATCGGTTGCCGCGTGCGGACCAGCCATTCGCGG
CGCTGGTGTCGAAGGTGCAGGCGAGCCGTTTCGGCACGCTGGCGTTCGTCAGGGTCTACGCCGGTCGTGTCACGGCGGGC
ACGTCGGTGACCAATGCGACGTCCGATCGGACCGAGCGGATCGGCCGGCTGCTGCGGATGCAGGCCGATGCGCAGATCGA
GATCGACGAAGCCCGTGCGGGCGACGTCGTCGCGGTCGTTGGCCTGAAGTCGGTCGTAGCCGGCGACACGTTGAGCGATC
CGGCGCACCCGATCGTGCTGGACGGCTTTGTCATTCCGGAGCCGGTGATCGAGGCGGTGGTCGAGCCGCGGCTTGGCCAG
GACCAGGAACGGCTGGGGCAGGCCCTGGCGCTGATGGCGCGCAGCGATCCGTCGCTGCGCGTCGTCGTCGACGCGGACAG
CGGCCAGACGCTGCTCCGCGGCATGGGCGAGTTGCATCTGCAGATCGCCGTCGAACGATTGAAGGAGGACTACAATGTCG
ATGCTGTCATCGGCGCCCCGGAGGTGGCCTATCGTGCGGCCGCGTCGCGGCCGAGCGAGGTCGATCACACCCTGCGCAAG
CAGAGTGGCGGCCCCGGCCAGATGGCGCGCGTTCGCCTCGCCTTCGCGCCCTTGGAGGAGGGCGGCGAGGGACTCGTATT
CGTCGACGAGACCGTCGGCGGCGCGATCCCGCGCGAGTTCATTCCGTCGATCGAGAAGGCGCTGCGCCAGTCGCTGCGCG
ACGGCGGGCCGGGCGGATATCCCGTGCTCGGCCAGCAAGTGACCCTCCTGGACGGCGCCTTCCATCAGAAGGATTCGTCC
GGGCTGGCCTTCGAGCTGGCGACCAGAGAGGCATTCCGGATCGGCTTCGAACGGGCCGCTCCGATCCTGCTCGAGCCCGT
GATGCGGGTCGTGGTGACGACGCCCGAGGACTATCTCGGCGGCATCATCGGCGATCTGCAGAGCCGGCGCGGCCGCATCG
TCGCGACCGAGCCGATCCCGCGCGGGCAGGAGGTCATCGCCGAAGTGCCGCTGGCGCGGTTGTTCAACTACGTCAGCGCG
CTGCGGTCGCTGTCGCAGGGGCGCGCCGTCCACGCGATGGCGTTCTCGCGCTATGCGCCGGCGCCGATAGGCGTCGCTGA
GAAGCTGATCGCGACGGCGTGA

Upstream 100 bases:

>100_bases
TCCTCACGGATTCGCGGCGCGATGCCGCATGGCTCGTCTTGTCCTGAAGAGACTCCAGCGGAGTTTGAAGATGACCCGCA
CGTTAAGAAATATCGGCATC

Downstream 100 bases:

>100_bases
CGACAACAAGAGATGAGCGGCGAGCAGCCGCTCATCTCATTCTCGCTTCAATTCGCCAGAAACGCCATCGAGATCACGTG
CTCGTAGCGACCATCGATCC

Product: protein chain elongation factor EF-G, GTP-binding

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MAHVDAGKTTLTERILLDTGKIHQAGDVHTGNTETDSHALEKKHGITISAAAISCEWRDAFITIIDTPGHVDFQIEVERS
LRVLDGAIAVFSAVSGVEPQSETVWRQADRLGVPRLCFVNKMDQVGADLQRTVEMIADRLGATPLVLQLPLRGEDGFAGV
VDLVAMKALYWDGAQPQPSAGAIPEELRSAAERQRQRLLETLADQDAAIMAAYVGGETISAADLKAAIRRACLAGRLTPV
LCGSAYRNVGVHPLLDAIVDYAPGPEDRPAVAGLDPRSGAAEHRLPRADQPFAALVSKVQASRFGTLAFVRVYAGRVTAG
TSVTNATSDRTERIGRLLRMQADAQIEIDEARAGDVVAVVGLKSVVAGDTLSDPAHPIVLDGFVIPEPVIEAVVEPRLGQ
DQERLGQALALMARSDPSLRVVVDADSGQTLLRGMGELHLQIAVERLKEDYNVDAVIGAPEVAYRAAASRPSEVDHTLRK
QSGGPGQMARVRLAFAPLEEGGEGLVFVDETVGGAIPREFIPSIEKALRQSLRDGGPGGYPVLGQQVTLLDGAFHQKDSS
GLAFELATREAFRIGFERAAPILLEPVMRVVVTTPEDYLGGIIGDLQSRRGRIVATEPIPRGQEVIAEVPLARLFNYVSA
LRSLSQGRAVHAMAFSRYAPAPIGVAEKLIATA

Sequences:

>Translated_673_residues
MAHVDAGKTTLTERILLDTGKIHQAGDVHTGNTETDSHALEKKHGITISAAAISCEWRDAFITIIDTPGHVDFQIEVERS
LRVLDGAIAVFSAVSGVEPQSETVWRQADRLGVPRLCFVNKMDQVGADLQRTVEMIADRLGATPLVLQLPLRGEDGFAGV
VDLVAMKALYWDGAQPQPSAGAIPEELRSAAERQRQRLLETLADQDAAIMAAYVGGETISAADLKAAIRRACLAGRLTPV
LCGSAYRNVGVHPLLDAIVDYAPGPEDRPAVAGLDPRSGAAEHRLPRADQPFAALVSKVQASRFGTLAFVRVYAGRVTAG
TSVTNATSDRTERIGRLLRMQADAQIEIDEARAGDVVAVVGLKSVVAGDTLSDPAHPIVLDGFVIPEPVIEAVVEPRLGQ
DQERLGQALALMARSDPSLRVVVDADSGQTLLRGMGELHLQIAVERLKEDYNVDAVIGAPEVAYRAAASRPSEVDHTLRK
QSGGPGQMARVRLAFAPLEEGGEGLVFVDETVGGAIPREFIPSIEKALRQSLRDGGPGGYPVLGQQVTLLDGAFHQKDSS
GLAFELATREAFRIGFERAAPILLEPVMRVVVTTPEDYLGGIIGDLQSRRGRIVATEPIPRGQEVIAEVPLARLFNYVSA
LRSLSQGRAVHAMAFSRYAPAPIGVAEKLIATA
>Mature_672_residues
AHVDAGKTTLTERILLDTGKIHQAGDVHTGNTETDSHALEKKHGITISAAAISCEWRDAFITIIDTPGHVDFQIEVERSL
RVLDGAIAVFSAVSGVEPQSETVWRQADRLGVPRLCFVNKMDQVGADLQRTVEMIADRLGATPLVLQLPLRGEDGFAGVV
DLVAMKALYWDGAQPQPSAGAIPEELRSAAERQRQRLLETLADQDAAIMAAYVGGETISAADLKAAIRRACLAGRLTPVL
CGSAYRNVGVHPLLDAIVDYAPGPEDRPAVAGLDPRSGAAEHRLPRADQPFAALVSKVQASRFGTLAFVRVYAGRVTAGT
SVTNATSDRTERIGRLLRMQADAQIEIDEARAGDVVAVVGLKSVVAGDTLSDPAHPIVLDGFVIPEPVIEAVVEPRLGQD
QERLGQALALMARSDPSLRVVVDADSGQTLLRGMGELHLQIAVERLKEDYNVDAVIGAPEVAYRAAASRPSEVDHTLRKQ
SGGPGQMARVRLAFAPLEEGGEGLVFVDETVGGAIPREFIPSIEKALRQSLRDGGPGGYPVLGQQVTLLDGAFHQKDSSG
LAFELATREAFRIGFERAAPILLEPVMRVVVTTPEDYLGGIIGDLQSRRGRIVATEPIPRGQEVIAEVPLARLFNYVSAL
RSLSQGRAVHAMAFSRYAPAPIGVAEKLIATA

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=681, Percent_Identity=38.0323054331865, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI19923640, Length=698, Percent_Identity=36.5329512893983, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI25306287, Length=697, Percent_Identity=34.4332855093257, Blast_Score=353, Evalue=4e-97,
Organism=Homo sapiens, GI25306283, Length=433, Percent_Identity=40.1847575057737, Blast_Score=277, Evalue=3e-74,
Organism=Homo sapiens, GI94966754, Length=138, Percent_Identity=37.6811594202899, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4503483, Length=141, Percent_Identity=40.4255319148936, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI157426893, Length=141, Percent_Identity=36.1702127659575, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=39.2857142857143, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1789738, Length=683, Percent_Identity=46.4128843338214, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1790835, Length=489, Percent_Identity=26.3803680981595, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI48994988, Length=166, Percent_Identity=36.144578313253, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788922, Length=146, Percent_Identity=36.3013698630137, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17533571, Length=681, Percent_Identity=36.1233480176211, Blast_Score=433, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17556745, Length=697, Percent_Identity=27.116212338594, Blast_Score=259, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17506493, Length=177, Percent_Identity=36.1581920903955, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=145, Percent_Identity=33.7931034482759, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71988819, Length=132, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323098, Length=679, Percent_Identity=38.5861561119293, Blast_Score=493, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6322359, Length=771, Percent_Identity=29.3125810635538, Blast_Score=306, Evalue=6e-84,
Organism=Saccharomyces cerevisiae, GI6324707, Length=438, Percent_Identity=25.7990867579909, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=438, Percent_Identity=25.7990867579909, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323320, Length=147, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324166, Length=148, Percent_Identity=33.7837837837838, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582462, Length=679, Percent_Identity=38.4388807069219, Blast_Score=496, Evalue=1e-140,
Organism=Drosophila melanogaster, GI221458488, Length=716, Percent_Identity=30.8659217877095, Blast_Score=319, Evalue=4e-87,
Organism=Drosophila melanogaster, GI24585711, Length=156, Percent_Identity=38.4615384615385, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585713, Length=156, Percent_Identity=38.4615384615385, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24585709, Length=156, Percent_Identity=38.4615384615385, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78706572, Length=141, Percent_Identity=36.1702127659575, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574573, Length=208, Percent_Identity=29.3269230769231, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 71881; Mature: 71750

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVDAGKTTLTERILLDTGKIHQAGDVHTGNTETDSHALEKKHGITISAAAISCEWRDA
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCE
FITIIDTPGHVDFQIEVERSLRVLDGAIAVFSAVSGVEPQSETVWRQADRLGVPRLCFVN
EEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHH
KMDQVGADLQRTVEMIADRLGATPLVLQLPLRGEDGFAGVVDLVAMKALYWDGAQPQPSA
CHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GAIPEELRSAAERQRQRLLETLADQDAAIMAAYVGGETISAADLKAAIRRACLAGRLTPV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHH
LCGSAYRNVGVHPLLDAIVDYAPGPEDRPAVAGLDPRSGAAEHRLPRADQPFAALVSKVQ
HHCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
ASRFGTLAFVRVYAGRVTAGTSVTNATSDRTERIGRLLRMQADAQIEIDEARAGDVVAVV
HHHCCHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
GLKSVVAGDTLSDPAHPIVLDGFVIPEPVIEAVVEPRLGQDQERLGQALALMARSDPSLR
CHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEE
VVVDADSGQTLLRGMGELHLQIAVERLKEDYNVDAVIGAPEVAYRAAASRPSEVDHTLRK
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCHHHHHHHHH
QSGGPGQMARVRLAFAPLEEGGEGLVFVDETVGGAIPREFIPSIEKALRQSLRDGGPGGY
CCCCCCHHEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PVLGQQVTLLDGAFHQKDSSGLAFELATREAFRIGFERAAPILLEPVMRVVVTTPEDYLG
CCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHEECCCHHHHH
GIIGDLQSRRGRIVATEPIPRGQEVIAEVPLARLFNYVSALRSLSQGRAVHAMAFSRYAP
HHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCC
APIGVAEKLIATA
CCCHHHHHHHHCC
>Mature Secondary Structure 
AHVDAGKTTLTERILLDTGKIHQAGDVHTGNTETDSHALEKKHGITISAAAISCEWRDA
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCE
FITIIDTPGHVDFQIEVERSLRVLDGAIAVFSAVSGVEPQSETVWRQADRLGVPRLCFVN
EEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHH
KMDQVGADLQRTVEMIADRLGATPLVLQLPLRGEDGFAGVVDLVAMKALYWDGAQPQPSA
CHHHHCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GAIPEELRSAAERQRQRLLETLADQDAAIMAAYVGGETISAADLKAAIRRACLAGRLTPV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHH
LCGSAYRNVGVHPLLDAIVDYAPGPEDRPAVAGLDPRSGAAEHRLPRADQPFAALVSKVQ
HHCHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHH
ASRFGTLAFVRVYAGRVTAGTSVTNATSDRTERIGRLLRMQADAQIEIDEARAGDVVAVV
HHHCCHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
GLKSVVAGDTLSDPAHPIVLDGFVIPEPVIEAVVEPRLGQDQERLGQALALMARSDPSLR
CHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEE
VVVDADSGQTLLRGMGELHLQIAVERLKEDYNVDAVIGAPEVAYRAAASRPSEVDHTLRK
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCHHHHHHHHH
QSGGPGQMARVRLAFAPLEEGGEGLVFVDETVGGAIPREFIPSIEKALRQSLRDGGPGGY
CCCCCCHHEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PVLGQQVTLLDGAFHQKDSSGLAFELATREAFRIGFERAAPILLEPVMRVVVTTPEDYLG
CCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHEECCCHHHHH
GIIGDLQSRRGRIVATEPIPRGQEVIAEVPLARLFNYVSALRSLSQGRAVHAMAFSRYAP
HHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCC
APIGVAEKLIATA
CCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA