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The map label for this gene is sufD [H]

Identifier: 146340501

GI number: 146340501

Start: 3735488

End: 3736810

Strand: Direct

Name: sufD [H]

Synonym: BRADO3543

Alternate gene names: 146340501

Gene position: 3735488-3736810 (Clockwise)

Preceding gene: 146340500

Following gene: 146340502

Centisome position: 50.1

GC content: 67.95

Gene sequence:

>1323_bases
ATGAACGTAGCTCTGGTCAAGAACGACAGCGGTCCGGCGGCGAGCAGCGTGTTCGCTGCCGCCCAGGGCCGGCTGCCCGG
CGCCGGCAAGGTTGTTGAGATCCGGCGCGAGGCCTTCGCGGCTTTCGAGCGCACCGGCCTGCCGCACCGGCGCATCGAGG
AATGGAAGTACACGGACTTGCGCGCCCTCGTGCGCGAGGTGCTGCCGCTGGCCGGCGCGCCGGATGCGGCGGCATTGGCA
CGGGCGAAGGCTGCGATCGCACCGATTTCGATCGATGGCGCGGCCAAGCTGGTGCTGGTCGATGGTGTCGTCGCCGCCGA
ACTGTCCGATCTCGCCGCGCTGCCGGCGGGCGTGGGTGTTCGAACGCTTCGTGCAGTGCTGGACGAGGCATCGAACGAGG
CTATCGGTGACCTGCTGTTGACCAAGGTCAGCGATCCCATGCTGTCGCTGAACGCGGCGCTCGCGACCGACGGCGTTGTC
GTGACGGTTGCCGATGGTGCGCAACTGACTGAGCCGCTGCACCTGATCCATGTCGCCACGGCGTCGAAGGCCGCACGCTA
CAGCCGCTCGCATGTGAAGGTCGGGCAGGGCGCCCGCGCGACCCTGGTCGAGACGTCGATCGCCGCCGAAGGCGTTGCCG
CCTATCAGGCCAATGATGCCGCTGTCATCTGGGTCGGCGACGGCGCTCAGCTGTCGCATATCCGTCTGATGCGCGATGCC
GCTGACGCGGTGAACGTCTCCTCCGAGCTGTTCACGGTCGGCGCCAAGTCGAAGCTCAGCCTGTTCAACATGACGAGCGG
CGGCGCGGTCAGCCGGCTGCAGGCGTTCTTCACGCTCGCCGGCGAAGCCAGCGAGCTGATCGTCAACGGCGTCAACCTGC
TGCGCGACAAGCAGCATGGCGATATGACCCTGGTGGTCGACCACGCCGTGCCCGGCTGCACCAGCCGCGAGAATTTTCGC
GCGGTGCTGGACGATCGGGCGCATTCGGTGTTCCAGGGGCGCATCATCGTCCGCCAGGACGCGCAGCAGACCGACGGCAA
GATGATGACGCGGGCCCTGCTGCTGTCCGACGAGGCCGAGGCCGACAGCAAGCCGGAGCTCGAGATCTTCGCCGACGACG
TCTCCTGCGGCCACGGCGCGACCGCCGGCGCGCTCGACGAGAGCCTGCTGTTCTATCTGCGCGCCCGCGGACTGCCGGAA
AAGCAGGCCCAGGCGCTGCTGATCCAGGCCTTCGTTGGCGAGGCAATCGAGGCAATCGAGGACGATGCTTTGCGCGAACG
CGTCATCGCCGCCGCCGAGCACTGGCTGGAGTCCCGCGCATGA

Upstream 100 bases:

>100_bases
CGCGTCGTGAAGAGCGGCGGCAAGGAGCTCGCGCTCGAGCTGGAGGCGTCCGGCTACGCCCAGTTCGAGGACGCAGCCTG
AGCCCGTGAATGGATCTGTG

Downstream 100 bases:

>100_bases
GTACGCATCCGGCTGTAAGCAACGGCAGCTACGACGTCGCCCGCATCCGCGAGGATTTTCCGGCGCTGGCGCTGCAGGTG
TACGGCAAGAAGCTTGTCTA

Product: sufD, needed for fhuF Fe-S center production/stability

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNVALVKNDSGPAASSVFAAAQGRLPGAGKVVEIRREAFAAFERTGLPHRRIEEWKYTDLRALVREVLPLAGAPDAAALA
RAKAAIAPISIDGAAKLVLVDGVVAAELSDLAALPAGVGVRTLRAVLDEASNEAIGDLLLTKVSDPMLSLNAALATDGVV
VTVADGAQLTEPLHLIHVATASKAARYSRSHVKVGQGARATLVETSIAAEGVAAYQANDAAVIWVGDGAQLSHIRLMRDA
ADAVNVSSELFTVGAKSKLSLFNMTSGGAVSRLQAFFTLAGEASELIVNGVNLLRDKQHGDMTLVVDHAVPGCTSRENFR
AVLDDRAHSVFQGRIIVRQDAQQTDGKMMTRALLLSDEAEADSKPELEIFADDVSCGHGATAGALDESLLFYLRARGLPE
KQAQALLIQAFVGEAIEAIEDDALRERVIAAAEHWLESRA

Sequences:

>Translated_440_residues
MNVALVKNDSGPAASSVFAAAQGRLPGAGKVVEIRREAFAAFERTGLPHRRIEEWKYTDLRALVREVLPLAGAPDAAALA
RAKAAIAPISIDGAAKLVLVDGVVAAELSDLAALPAGVGVRTLRAVLDEASNEAIGDLLLTKVSDPMLSLNAALATDGVV
VTVADGAQLTEPLHLIHVATASKAARYSRSHVKVGQGARATLVETSIAAEGVAAYQANDAAVIWVGDGAQLSHIRLMRDA
ADAVNVSSELFTVGAKSKLSLFNMTSGGAVSRLQAFFTLAGEASELIVNGVNLLRDKQHGDMTLVVDHAVPGCTSRENFR
AVLDDRAHSVFQGRIIVRQDAQQTDGKMMTRALLLSDEAEADSKPELEIFADDVSCGHGATAGALDESLLFYLRARGLPE
KQAQALLIQAFVGEAIEAIEDDALRERVIAAAEHWLESRA
>Mature_440_residues
MNVALVKNDSGPAASSVFAAAQGRLPGAGKVVEIRREAFAAFERTGLPHRRIEEWKYTDLRALVREVLPLAGAPDAAALA
RAKAAIAPISIDGAAKLVLVDGVVAAELSDLAALPAGVGVRTLRAVLDEASNEAIGDLLLTKVSDPMLSLNAALATDGVV
VTVADGAQLTEPLHLIHVATASKAARYSRSHVKVGQGARATLVETSIAAEGVAAYQANDAAVIWVGDGAQLSHIRLMRDA
ADAVNVSSELFTVGAKSKLSLFNMTSGGAVSRLQAFFTLAGEASELIVNGVNLLRDKQHGDMTLVVDHAVPGCTSRENFR
AVLDDRAHSVFQGRIIVRQDAQQTDGKMMTRALLLSDEAEADSKPELEIFADDVSCGHGATAGALDESLLFYLRARGLPE
KQAQALLIQAFVGEAIEAIEDDALRERVIAAAEHWLESRA

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI1787971, Length=393, Percent_Identity=32.0610687022901, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000825
- InterPro:   IPR011542 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 46311; Mature: 46311

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVALVKNDSGPAASSVFAAAQGRLPGAGKVVEIRREAFAAFERTGLPHRRIEEWKYTDL
CCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHH
RALVREVLPLAGAPDAAALARAKAAIAPISIDGAAKLVLVDGVVAAELSDLAALPAGVGV
HHHHHHHHCCCCCCCHHHHHHHHHHCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCCHH
RTLRAVLDEASNEAIGDLLLTKVSDPMLSLNAALATDGVVVTVADGAQLTEPLHLIHVAT
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEHH
ASKAARYSRSHVKVGQGARATLVETSIAAEGVAAYQANDAAVIWVGDGAQLSHIRLMRDA
HHHHHHHHHCCEECCCCCCEEEEEHHHHHCCEEEEECCCEEEEEECCCCCCHHHHHHHHH
ADAVNVSSELFTVGAKSKLSLFNMTSGGAVSRLQAFFTLAGEASELIVNGVNLLRDKQHG
HHHHCCCHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
DMTLVVDHAVPGCTSRENFRAVLDDRAHSVFQGRIIVRQDAQQTDGKMMTRALLLSDEAE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHCCCCC
ADSKPELEIFADDVSCGHGATAGALDESLLFYLRARGLPEKQAQALLIQAFVGEAIEAIE
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DDALRERVIAAAEHWLESRA
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVALVKNDSGPAASSVFAAAQGRLPGAGKVVEIRREAFAAFERTGLPHRRIEEWKYTDL
CCEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHH
RALVREVLPLAGAPDAAALARAKAAIAPISIDGAAKLVLVDGVVAAELSDLAALPAGVGV
HHHHHHHHCCCCCCCHHHHHHHHHHCCEEEECCCEEEEEECCHHHHHHHHHHHCCCCCHH
RTLRAVLDEASNEAIGDLLLTKVSDPMLSLNAALATDGVVVTVADGAQLTEPLHLIHVAT
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEHH
ASKAARYSRSHVKVGQGARATLVETSIAAEGVAAYQANDAAVIWVGDGAQLSHIRLMRDA
HHHHHHHHHCCEECCCCCCEEEEEHHHHHCCEEEEECCCEEEEEECCCCCCHHHHHHHHH
ADAVNVSSELFTVGAKSKLSLFNMTSGGAVSRLQAFFTLAGEASELIVNGVNLLRDKQHG
HHHHCCCHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
DMTLVVDHAVPGCTSRENFRAVLDDRAHSVFQGRIIVRQDAQQTDGKMMTRALLLSDEAE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHCCCCC
ADSKPELEIFADDVSCGHGATAGALDESLLFYLRARGLPEKQAQALLIQAFVGEAIEAIE
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DDALRERVIAAAEHWLESRA
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]