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The map label for this gene is sufC [H]

Identifier: 146340500

GI number: 146340500

Start: 3734716

End: 3735468

Strand: Direct

Name: sufC [H]

Synonym: BRADO3542

Alternate gene names: 146340500

Gene position: 3734716-3735468 (Clockwise)

Preceding gene: 146340499

Following gene: 146340501

Centisome position: 50.09

GC content: 63.35

Gene sequence:

>753_bases
ATGGCACTACTCGAAATCAAGAACCTGCAGGTCCGCGTCGAGGAGCGCGAGATTCTCCACGGGCTGACGCTCACGATCGA
CGAAGGCAAGGTGCATGCGATCATGGGGCCGAACGGCTCCGGCAAGTCGACGCTCTCCCACGTCATCGCCGGCAAGCCGG
GCTATGAGGTCACCGGCGGCGAGATCCTGTTCAAGGGCGAGGACTTGCTCGCCATGGATCCGGACGAGCGTGCCGCCAAG
GGTGTGTTTCTGGCGTTTCAGTATCCGGTGGAAATCCCCGGTGTCGCCACCATGACCTTCCTGCGCACCGCGCTCAACGC
GCAGCGCAAGGCGCGTGGCGAGGAGGAATATTCGACCCCGGACTTCCTGAAGAAGGTCCGCGAAATTTCCAAGCAGCTCA
GCATTCCGCAGGACATGCTGAAGCGCGGCGTCAATGTCGGCTTCTCCGGCGGCGAGAAGAAGCGCAATGAGGTGCTGCAA
ATGGCGCTGTTCCAGCCGTCGCTCTGCATCCTCGACGAGATGGATTCTGGCCTCGACATCGACGCGCTGCGCATCGCCGC
CGACGGCGTCAACGCGCTGCGCGCGCCCGAGCGCTCGATGATCGTGATCACCCACTATCAGCGGCTTTTGAACTACATCG
TGCCCGACGTCGTTCACGTGATGTCGAAGGGCCGCGTCGTGAAGAGCGGCGGCAAGGAGCTCGCGCTCGAGCTGGAGGCG
TCCGGCTACGCCCAGTTCGAGGACGCAGCCTGA

Upstream 100 bases:

>100_bases
TATCCAAGATCACGACCACCAGGATATTGCAGCAATAAAAGTTCGGCTCGACCGCATTGAAAAGCGTCTGGAGCTGATTG
ACCAGGATCAGGACTGACCC

Downstream 100 bases:

>100_bases
GCCCGTGAATGGATCTGTGATGAACGTAGCTCTGGTCAAGAACGACAGCGGTCCGGCGGCGAGCAGCGTGTTCGCTGCCG
CCCAGGGCCGGCTGCCCGGC

Product: SufC, related to ABC transporter associated with Fe-S cluster assembly ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MALLEIKNLQVRVEEREILHGLTLTIDEGKVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMDPDERAAK
GVFLAFQYPVEIPGVATMTFLRTALNAQRKARGEEEYSTPDFLKKVREISKQLSIPQDMLKRGVNVGFSGGEKKRNEVLQ
MALFQPSLCILDEMDSGLDIDALRIAADGVNALRAPERSMIVITHYQRLLNYIVPDVVHVMSKGRVVKSGGKELALELEA
SGYAQFEDAA

Sequences:

>Translated_250_residues
MALLEIKNLQVRVEEREILHGLTLTIDEGKVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMDPDERAAK
GVFLAFQYPVEIPGVATMTFLRTALNAQRKARGEEEYSTPDFLKKVREISKQLSIPQDMLKRGVNVGFSGGEKKRNEVLQ
MALFQPSLCILDEMDSGLDIDALRIAADGVNALRAPERSMIVITHYQRLLNYIVPDVVHVMSKGRVVKSGGKELALELEA
SGYAQFEDAA
>Mature_249_residues
ALLEIKNLQVRVEEREILHGLTLTIDEGKVHAIMGPNGSGKSTLSHVIAGKPGYEVTGGEILFKGEDLLAMDPDERAAKG
VFLAFQYPVEIPGVATMTFLRTALNAQRKARGEEEYSTPDFLKKVREISKQLSIPQDMLKRGVNVGFSGGEKKRNEVLQM
ALFQPSLCILDEMDSGLDIDALRIAADGVNALRAPERSMIVITHYQRLLNYIVPDVVHVMSKGRVVKSGGKELALELEAS
GYAQFEDAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=224, Percent_Identity=29.4642857142857, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=59.8360655737705, Blast_Score=307, Evalue=5e-85,
Organism=Escherichia coli, GI1787500, Length=256, Percent_Identity=30.078125, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788225, Length=256, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786698, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789962, Length=244, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787370, Length=219, Percent_Identity=26.4840182648402, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787029, Length=242, Percent_Identity=25.2066115702479, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=22.7272727272727, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=231, Percent_Identity=25.974025974026, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=220, Percent_Identity=29.0909090909091, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=221, Percent_Identity=28.5067873303167, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=244, Percent_Identity=25.4098360655738, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=250, Percent_Identity=26.4, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27408; Mature: 27277

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLEIKNLQVRVEEREILHGLTLTIDEGKVHAIMGPNGSGKSTLSHVIAGKPGYEVTGG
CCEEEECCCEEEEHHHHHHCCEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCEECCC
EILFKGEDLLAMDPDERAAKGVFLAFQYPVEIPGVATMTFLRTALNAQRKARGEEEYSTP
EEEEECCCEEEECCCCHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
DFLKKVREISKQLSIPQDMLKRGVNVGFSGGEKKRNEVLQMALFQPSLCILDEMDSGLDI
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
DALRIAADGVNALRAPERSMIVITHYQRLLNYIVPDVVHVMSKGRVVKSGGKELALELEA
HHEEEECCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEC
SGYAQFEDAA
CCCCCCCCCC
>Mature Secondary Structure 
ALLEIKNLQVRVEEREILHGLTLTIDEGKVHAIMGPNGSGKSTLSHVIAGKPGYEVTGG
CEEEECCCEEEEHHHHHHCCEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCEECCC
EILFKGEDLLAMDPDERAAKGVFLAFQYPVEIPGVATMTFLRTALNAQRKARGEEEYSTP
EEEEECCCEEEECCCCHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
DFLKKVREISKQLSIPQDMLKRGVNVGFSGGEKKRNEVLQMALFQPSLCILDEMDSGLDI
HHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
DALRIAADGVNALRAPERSMIVITHYQRLLNYIVPDVVHVMSKGRVVKSGGKELALELEA
HHEEEECCCCHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEC
SGYAQFEDAA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]