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The map label for this gene is glxA [H]

Identifier: 146340442

GI number: 146340442

Start: 3664162

End: 3665109

Strand: Direct

Name: glxA [H]

Synonym: BRADO3482

Alternate gene names: 146340442

Gene position: 3664162-3665109 (Clockwise)

Preceding gene: 146340440

Following gene: 146340443

Centisome position: 49.14

GC content: 70.36

Gene sequence:

>948_bases
ATGATCGGCGTGCTCATCTTCCCGGACTTTCAGTTGCTCGACGCCGCCGGCCCGATCTCGGTGTTCGAGATCGCCGCGCG
CTATGCCGGCGCCGCGCCGACGATCCGCGTGGTGGCGGCCGCGCCGGGGCCGGTGCGCTCCTCGTCGGGCGCCGAGATGC
TCGCGCGGAAGTTCGGCTCCGTCTCGGCGTTGTCGACCTTGCTGATCGCCGGCGGCGACGGCGTCGAGGCGGCCAGCCGC
AATGCCTGCACGTTGAATTTCGTTCGCAAGGTCGCGCGTCGCGGCACCCGCGTGGCCAGCGTCTGCTCGGGCGCCTTCGT
ACTTGCCGAGGCCGGCCTGCTCGACGGCAAGCGCGCGACCACGCATTGGCAGCGGACGCGCCAGTTTCTCCGCGCCTATC
CAGACGTGAAGCTCGAGCCCGACAGCATCTATGTGCGCGACGGTCAGATCTGGACTTCGGCCGGCATCACCGCCGGCATC
GATCTCGCGCTGGCTATGGTGGCGGAGGATCACGGCGAGCAGATCGCGCAGAAGACCGCGCGGCAGCTCGTGCTCTATCA
CCGCCGCAGCGGCGGCCAGTCGCAGTTCTCCTCGCTGCTGGAACTGAAGGCGCCGAGCGGCCGGTTCGCCGATCTCTTGA
CCTGGGCGCGCGAGCATCTCGATGCGCCGCTGTCGGTCGATGATCTCGCCGAGCGCGCCGGCATGAGCACGCGGCACTTC
ACCCGCGCCTTCGTTGCCGAAACCGGGACCACGCCCTCCAAGGCGATCGAGCGCCTGCGGCTGGAGGTGGCGCGCGATCG
TGTGCAGGCCTCGCACCAGCCGATCGAGTTGGTGGCCGAAGCGGCCGGCTTTCGCGATCCCGAGCGGATGCGCCGCGCCT
TCATCCGCGCCTTTGGCCAGCCGCCGCAGGCGTTGCGACGCGCGGCGCGCGCACAGCCGGCTGGTTGA

Upstream 100 bases:

>100_bases
CGGGCAATGACGGGTTGACGCCAACGATCCTGCATGATCCGCTGCCTGTCTCAAATGTCAAAGTTCCCTCGATTTCAGAC
AGACCGCTGCGGAGTCCTTC

Downstream 100 bases:

>100_bases
TCTGAATCAGTCGCGGGGAACCGCGACCGGCTATCCTGCCTGCTTGATCTCTGAGCGCGCGGAGCAGGACGAGTGACGGT
TGACGGCGCTGAACGCGCGA

Product: bifunctional transcriptional regulator/glutamine amidotransferase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MIGVLIFPDFQLLDAAGPISVFEIAARYAGAAPTIRVVAAAPGPVRSSSGAEMLARKFGSVSALSTLLIAGGDGVEAASR
NACTLNFVRKVARRGTRVASVCSGAFVLAEAGLLDGKRATTHWQRTRQFLRAYPDVKLEPDSIYVRDGQIWTSAGITAGI
DLALAMVAEDHGEQIAQKTARQLVLYHRRSGGQSQFSSLLELKAPSGRFADLLTWAREHLDAPLSVDDLAERAGMSTRHF
TRAFVAETGTTPSKAIERLRLEVARDRVQASHQPIELVAEAAGFRDPERMRRAFIRAFGQPPQALRRAARAQPAG

Sequences:

>Translated_315_residues
MIGVLIFPDFQLLDAAGPISVFEIAARYAGAAPTIRVVAAAPGPVRSSSGAEMLARKFGSVSALSTLLIAGGDGVEAASR
NACTLNFVRKVARRGTRVASVCSGAFVLAEAGLLDGKRATTHWQRTRQFLRAYPDVKLEPDSIYVRDGQIWTSAGITAGI
DLALAMVAEDHGEQIAQKTARQLVLYHRRSGGQSQFSSLLELKAPSGRFADLLTWAREHLDAPLSVDDLAERAGMSTRHF
TRAFVAETGTTPSKAIERLRLEVARDRVQASHQPIELVAEAAGFRDPERMRRAFIRAFGQPPQALRRAARAQPAG
>Mature_315_residues
MIGVLIFPDFQLLDAAGPISVFEIAARYAGAAPTIRVVAAAPGPVRSSSGAEMLARKFGSVSALSTLLIAGGDGVEAASR
NACTLNFVRKVARRGTRVASVCSGAFVLAEAGLLDGKRATTHWQRTRQFLRAYPDVKLEPDSIYVRDGQIWTSAGITAGI
DLALAMVAEDHGEQIAQKTARQLVLYHRRSGGQSQFSSLLELKAPSGRFADLLTWAREHLDAPLSVDDLAERAGMSTRHF
TRAFVAETGTTPSKAIERLRLEVARDRVQASHQPIELVAEAAGFRDPERMRRAFIRAFGQPPQALRRAARAQPAG

Specific function: May Be A Transcriptional Activator Of Genes Involved In The Multiple Antibiotic Resistance (Mar) Phenotype. It Can Also Activate Genes Such As Soda, Zwf And Micf. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081928, Length=95, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33970; Mature: 33970

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVLIFPDFQLLDAAGPISVFEIAARYAGAAPTIRVVAAAPGPVRSSSGAEMLARKFGS
CEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
VSALSTLLIAGGDGVEAASRNACTLNFVRKVARRGTRVASVCSGAFVLAEAGLLDGKRAT
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
THWQRTRQFLRAYPDVKLEPDSIYVRDGQIWTSAGITAGIDLALAMVAEDHGEQIAQKTA
HHHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLVLYHRRSGGQSQFSSLLELKAPSGRFADLLTWAREHLDAPLSVDDLAERAGMSTRHF
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHH
TRAFVAETGTTPSKAIERLRLEVARDRVQASHQPIELVAEAAGFRDPERMRRAFIRAFGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
PPQALRRAARAQPAG
CHHHHHHHHCCCCCC
>Mature Secondary Structure
MIGVLIFPDFQLLDAAGPISVFEIAARYAGAAPTIRVVAAAPGPVRSSSGAEMLARKFGS
CEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCC
VSALSTLLIAGGDGVEAASRNACTLNFVRKVARRGTRVASVCSGAFVLAEAGLLDGKRAT
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
THWQRTRQFLRAYPDVKLEPDSIYVRDGQIWTSAGITAGIDLALAMVAEDHGEQIAQKTA
HHHHHHHHHHHHCCCCEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQLVLYHRRSGGQSQFSSLLELKAPSGRFADLLTWAREHLDAPLSVDDLAERAGMSTRHF
HHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHH
TRAFVAETGTTPSKAIERLRLEVARDRVQASHQPIELVAEAAGFRDPERMRRAFIRAFGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
PPQALRRAARAQPAG
CHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]