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The map label for this gene is trxC [C]

Identifier: 146340188

GI number: 146340188

Start: 3405033

End: 3405473

Strand: Direct

Name: trxC [C]

Synonym: BRADO3204

Alternate gene names: 146340188

Gene position: 3405033-3405473 (Clockwise)

Preceding gene: 146340187

Following gene: 146340189

Centisome position: 45.66

GC content: 68.25

Gene sequence:

>441_bases
ATGAGCGAGACCTTCCAACTGGTGTGCGGCCATTGCGGGCAGATCAACCGGCTGCCCGCGGGCCGGGCGCCCACCCAGGG
CAAATGCGGCAAGTGCCACGCGCCGCTGTTTTCCGGTCATCCGATCGAGGTCGACCAGGCCGGCTTCACGCGCCACCTCG
CCAACAGCGACCTGCCTTTGCTGGTCGATGTCTGGGCGCCGTGGTGCGGCCCGTGCCGGGCAATGGCGCCGATGTTCGCG
CGCGCCGCCGAGGCGCTCGAGCCGCGCGTGCAGCTTCTGAAGCTGAACTCCGACGAGGCGCCGGAGGTCTCGGCGAAGTT
CGGCATCTCCGGAATTCCCACCCTGCTGCTGCTGCAGAAGGGAAGGGAGCTGGCGCGGATCTCGGGTGCAATGGACTCGC
AACGAATCGTCGCCTGGACGTTGTCCGGCCTGCGGCAGTGA

Upstream 100 bases:

>100_bases
TCCTGCGCAAGATGAAGCGCGGCACGCCGGAGCCCTTCTACGAGAAGTTCCTGCTCGACCGGCTCAACATCGGCAAGATC
AAGGAAGTCAGGACGGGCAC

Downstream 100 bases:

>100_bases
CGCCGCGGCACCGGCTTGATCACGCTCAAATGCAACGATGAGGGACCATGCCATGAACGTCGATAAAGCAGTTCTCACCT
TCGCAGGGTTCGTCGTCCTG

Product: putative thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSETFQLVCGHCGQINRLPAGRAPTQGKCGKCHAPLFSGHPIEVDQAGFTRHLANSDLPLLVDVWAPWCGPCRAMAPMFA
RAAEALEPRVQLLKLNSDEAPEVSAKFGISGIPTLLLLQKGRELARISGAMDSQRIVAWTLSGLRQ

Sequences:

>Translated_146_residues
MSETFQLVCGHCGQINRLPAGRAPTQGKCGKCHAPLFSGHPIEVDQAGFTRHLANSDLPLLVDVWAPWCGPCRAMAPMFA
RAAEALEPRVQLLKLNSDEAPEVSAKFGISGIPTLLLLQKGRELARISGAMDSQRIVAWTLSGLRQ
>Mature_145_residues
SETFQLVCGHCGQINRLPAGRAPTQGKCGKCHAPLFSGHPIEVDQAGFTRHLANSDLPLLVDVWAPWCGPCRAMAPMFAR
AAEALEPRVQLLKLNSDEAPEVSAKFGISGIPTLLLLQKGRELARISGAMDSQRIVAWTLSGLRQ

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5031973, Length=106, Percent_Identity=31.1320754716981, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788936, Length=137, Percent_Identity=37.2262773722628, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI87082331, Length=95, Percent_Identity=37.8947368421053, Blast_Score=78, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI212646193, Length=88, Percent_Identity=34.0909090909091, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566189, Length=91, Percent_Identity=37.3626373626374, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569137, Length=88, Percent_Identity=38.6363636363636, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209454, Length=91, Percent_Identity=37.3626373626374, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323072, Length=82, Percent_Identity=40.2439024390244, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321648, Length=82, Percent_Identity=37.8048780487805, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573567, Length=94, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358065, Length=98, Percent_Identity=30.6122448979592, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 15772; Mature: 15640

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETFQLVCGHCGQINRLPAGRAPTQGKCGKCHAPLFSGHPIEVDQAGFTRHLANSDLPL
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCE
LVDVWAPWCGPCRAMAPMFARAAEALEPRVQLLKLNSDEAPEVSAKFGISGIPTLLLLQK
EEEECCCCCCHHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCHHHCCCCCCCHHHHHHC
GRELARISGAMDSQRIVAWTLSGLRQ
CHHHHHHHCCCCCCHHHEEEHHHHCC
>Mature Secondary Structure 
SETFQLVCGHCGQINRLPAGRAPTQGKCGKCHAPLFSGHPIEVDQAGFTRHLANSDLPL
CCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCE
LVDVWAPWCGPCRAMAPMFARAAEALEPRVQLLKLNSDEAPEVSAKFGISGIPTLLLLQK
EEEECCCCCCHHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCHHHCCCCCCCHHHHHHC
GRELARISGAMDSQRIVAWTLSGLRQ
CHHHHHHHCCCCCCHHHEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]