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The map label for this gene is groES [H]

Identifier: 146339699

GI number: 146339699

Start: 2896128

End: 2896442

Strand: Direct

Name: groES [H]

Synonym: BRADO2696

Alternate gene names: 146339699

Gene position: 2896128-2896442 (Clockwise)

Preceding gene: 146339696

Following gene: 146339700

Centisome position: 38.84

GC content: 65.4

Gene sequence:

>315_bases
ATGCATTTCCGTCCATTGCACGACCGCGTGCTCGTGCGCCGTATCGATGCCGAGGAGAAGACCAAGGGCGGCATCATCAT
TCCCGACACCGCCAAGGAGAAGCCGCAGGAGGGCGAGATCGTCGCCGCCGGTCCCGGCGCGCGGAATGAGCAGGGACAAC
TCGTGCCGCTCGACGTCAAGCCCGGCGACCGCGTGCTGTTCGGCAAGTGGTCGGGGACCGAGGTGAAGATCGACGGCAAG
GATCTCCTGATCATGAAGGAGAGCGACCTGCTCGGCATCGTCGACGCCCCCGTCGCGGCGAAGAAAGCCGCGTGA

Upstream 100 bases:

>100_bases
CTCTTGAACGAAAATCTCGGCTTTCCTAGGTCGTTGCTCGCCCGGGGGCCTCATGGGACCCGAGGCTTATGACATCGCTG
ATCTGTAAAGGAGGATGTGC

Downstream 100 bases:

>100_bases
TCCCTCAAACTGACAGTCATCGGTAGACAAGGAGACGATGAACATGGCTGCCAAGGACGTGAAGTTTTCCACCGACGCGC
GCGACCGTATGCTGCGCGGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein 1; Protein Cpn10 1 [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MHFRPLHDRVLVRRIDAEEKTKGGIIIPDTAKEKPQEGEIVAAGPGARNEQGQLVPLDVKPGDRVLFGKWSGTEVKIDGK
DLLIMKESDLLGIVDAPVAAKKAA

Sequences:

>Translated_104_residues
MHFRPLHDRVLVRRIDAEEKTKGGIIIPDTAKEKPQEGEIVAAGPGARNEQGQLVPLDVKPGDRVLFGKWSGTEVKIDGK
DLLIMKESDLLGIVDAPVAAKKAA
>Mature_104_residues
MHFRPLHDRVLVRRIDAEEKTKGGIIIPDTAKEKPQEGEIVAAGPGARNEQGQLVPLDVKPGDRVLFGKWSGTEVKIDGK
DLLIMKESDLLGIVDAPVAAKKAA

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=43.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=40, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790585, Length=97, Percent_Identity=48.4536082474227, Blast_Score=91, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=54.9450549450549, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=38.2022471910112, Blast_Score=67, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356029, Length=90, Percent_Identity=46.6666666666667, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=42.6966292134831, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 11261; Mature: 11261

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRPLHDRVLVRRIDAEEKTKGGIIIPDTAKEKPQEGEIVAAGPGARNEQGQLVPLDVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
PGDRVLFGKWSGTEVKIDGKDLLIMKESDLLGIVDAPVAAKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MHFRPLHDRVLVRRIDAEEKTKGGIIIPDTAKEKPQEGEIVAAGPGARNEQGQLVPLDVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEECC
PGDRVLFGKWSGTEVKIDGKDLLIMKESDLLGIVDAPVAAKKAA
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808920; 12597275 [H]