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The map label for this gene is aer [H]

Identifier: 146339570

GI number: 146339570

Start: 2741865

End: 2743556

Strand: Direct

Name: aer [H]

Synonym: BRADO2561

Alternate gene names: 146339570

Gene position: 2741865-2743556 (Clockwise)

Preceding gene: 146339569

Following gene: 146339571

Centisome position: 36.77

GC content: 66.49

Gene sequence:

>1692_bases
ATGCGTAAGAACCTGCCCGTCACCACTGTCGAATATCCGATCACGGATGACACGCTGATCGTGTCGAAGACCGATGCGAA
GGGCAAGTTGACCTTCTTCAACGAGGACTTTGTCAAGGCCGCCGGCTTCACCGAAGCCGAGTTGATGGGGCAGCCGCACA
ACATCGTGCGTCATCCCGACATGCCGCCTGAAGCGTTCGATAATCTCTGGACGACGCTGAAGCACGGGCGCCCCTGGGTC
GGCGCGGTCAAGAACCGGCGCAAGAACGGCGACTACTACTGGGTGCTCGCGACGGCGTCGCCGATCGTGCAGAACGGCCA
GGTCACGGGCTACACCTCGGTGCGCACCAAGCTGCCGTCGGATCAGCGCGCGGAGGCCGAGCAGGTCTATGCCGCGATCC
GCGAGAAGAAGCCGCACGGCTACAAGATCGAGGACGGCATCGTGCGCCGCCGCTCGCTGTTCGACCATCTTGCTGTCTTC
ACCGGCACCATCGCATCCAGGCTGCGAACACTGATCGGGCTGCAGACGCTGTTTCTGATCGTGCTCGGCGGCATGTCGTT
GAGCGCGGGCGGGGCCGGAAGCATGGCCGCCGCCGGGATAGCGGCGGCGGGCATCGTGCTCTGCGGCTTGGTCGGACTGA
GAACGATGAACGTCATCGTCGGGCCGCTCACGCACGTCAACGAGACCATGGAGAGCATCACCCAGGGCAAGCTCGACACA
CGCATGCGCATCGAGCGCGACGACGAGATCGGCCGCGCCTTGCGCAACCTGCAGACTGTGCAGACCATGGTGCGCTTCAA
CGCCCGGGAGCTGAAGGAGCAGGAGCAGCGCGCCGAAGTGTCGCGCAAGCAGGAGATGTCGAAGCTCGCGGAAAGCTTCG
AGGGCGCCATCGGCAACATCGTCGATACCGTCTCCTCGGCTTCGAGCGAGCTCGAGAGCTCGGCGAACTCTCTGTCAGGC
ACCGCCTTGCGCGGACAGGAACTGTCGACCACCGTGGCCGCGGCTTCGGAGGAAGCTTCGGCCAATGTTCAGGCCGTGGC
TTCGGCGACCGAGGAGCTGACGTCGTCGGTCAAGGAGATCAGCCGCCAGGTGCAGGAGTCCGCGCGGATCGCCTCCGATG
CCGTCGACCAGGCGCGCCGCACCAATGATCGCGTCGGCGAACTGTCGAAGGCCGCGACCCGCATCGGCGACGTCGTCGAA
CTGATCAATACGATCGCCGGCCAGACCAATCTGCTCGCGCTCAACGCCACCATCGAGGCCGCGCGTGCCGGCGAGGCCGG
CCGCGGCTTTGCGGTCGTCGCCTCCGAGGTCAAGGCGCTGGCCGAGCAGACCGCGAAGGCCACCGGCGAGATCGGCCAGC
AGATCTCCGGCATCCAGGCGGCCACGCAGGAATCCGTCGGCGCCATCCGGGAAATCTCGACCACGATCGAGCGGCTGTCC
GAGATTGCCGCGACGGTTGCCGCCGCCGTCGAGGAGCAGGGCGCAGCCACGTCCGAGATCGCCCGCAACATCCAGCACGC
CGCCGCCGGCACGCAGGAGGTCTCGTCCAACATCGTCGACGTGCAGCGCGGCGCCAGCGAGACCGGCGAAACGTCGGGCC
AGGTGCTTACGGCGGCGCGTCAGCTCTCCGGCGACAGCCAGCGTCTCAAGCAGGAGGTCAGCCGCTTCCTGCAATCGGTG
CGCGCGGCCTGA

Upstream 100 bases:

>100_bases
AACCCGGCGATCAATGATGGGCAAAGAGCTGAAAAATTAATCATGCCAACGACGGCGTGACGTTTTCCCCCCGCATCCCC
GGAAGATTGGAAGCTGCGCC

Downstream 100 bases:

>100_bases
TCGCGGCGAGGTGGACCCACCGGCGATCTCATCAGGTGCGATGAGTGAACGAAGCTGGCGCGGCATGCCGCGGCCGGGTA
CGCTAGTCCTGTCATGAGAC

Product: putative sensory transducer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRKNLPVTTVEYPITDDTLIVSKTDAKGKLTFFNEDFVKAAGFTEAELMGQPHNIVRHPDMPPEAFDNLWTTLKHGRPWV
GAVKNRRKNGDYYWVLATASPIVQNGQVTGYTSVRTKLPSDQRAEAEQVYAAIREKKPHGYKIEDGIVRRRSLFDHLAVF
TGTIASRLRTLIGLQTLFLIVLGGMSLSAGGAGSMAAAGIAAAGIVLCGLVGLRTMNVIVGPLTHVNETMESITQGKLDT
RMRIERDDEIGRALRNLQTVQTMVRFNARELKEQEQRAEVSRKQEMSKLAESFEGAIGNIVDTVSSASSELESSANSLSG
TALRGQELSTTVAAASEEASANVQAVASATEELTSSVKEISRQVQESARIASDAVDQARRTNDRVGELSKAATRIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQISGIQAATQESVGAIREISTTIERLS
EIAATVAAAVEEQGAATSEIARNIQHAAAGTQEVSSNIVDVQRGASETGETSGQVLTAARQLSGDSQRLKQEVSRFLQSV
RAA

Sequences:

>Translated_563_residues
MRKNLPVTTVEYPITDDTLIVSKTDAKGKLTFFNEDFVKAAGFTEAELMGQPHNIVRHPDMPPEAFDNLWTTLKHGRPWV
GAVKNRRKNGDYYWVLATASPIVQNGQVTGYTSVRTKLPSDQRAEAEQVYAAIREKKPHGYKIEDGIVRRRSLFDHLAVF
TGTIASRLRTLIGLQTLFLIVLGGMSLSAGGAGSMAAAGIAAAGIVLCGLVGLRTMNVIVGPLTHVNETMESITQGKLDT
RMRIERDDEIGRALRNLQTVQTMVRFNARELKEQEQRAEVSRKQEMSKLAESFEGAIGNIVDTVSSASSELESSANSLSG
TALRGQELSTTVAAASEEASANVQAVASATEELTSSVKEISRQVQESARIASDAVDQARRTNDRVGELSKAATRIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQISGIQAATQESVGAIREISTTIERLS
EIAATVAAAVEEQGAATSEIARNIQHAAAGTQEVSSNIVDVQRGASETGETSGQVLTAARQLSGDSQRLKQEVSRFLQSV
RAA
>Mature_563_residues
MRKNLPVTTVEYPITDDTLIVSKTDAKGKLTFFNEDFVKAAGFTEAELMGQPHNIVRHPDMPPEAFDNLWTTLKHGRPWV
GAVKNRRKNGDYYWVLATASPIVQNGQVTGYTSVRTKLPSDQRAEAEQVYAAIREKKPHGYKIEDGIVRRRSLFDHLAVF
TGTIASRLRTLIGLQTLFLIVLGGMSLSAGGAGSMAAAGIAAAGIVLCGLVGLRTMNVIVGPLTHVNETMESITQGKLDT
RMRIERDDEIGRALRNLQTVQTMVRFNARELKEQEQRAEVSRKQEMSKLAESFEGAIGNIVDTVSSASSELESSANSLSG
TALRGQELSTTVAAASEEASANVQAVASATEELTSSVKEISRQVQESARIASDAVDQARRTNDRVGELSKAATRIGDVVE
LINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQISGIQAATQESVGAIREISTTIERLS
EIAATVAAAVEEQGAATSEIARNIQHAAAGTQEVSSNIVDVQRGASETGETSGQVLTAARQLSGDSQRLKQEVSRFLQSV
RAA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=527, Percent_Identity=31.4990512333966, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1787690, Length=390, Percent_Identity=28.4615384615385, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI2367378, Length=252, Percent_Identity=32.1428571428571, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=328, Percent_Identity=28.3536585365854, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788195, Length=251, Percent_Identity=32.2709163346614, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 60099; Mature: 60099

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLPVTTVEYPITDDTLIVSKTDAKGKLTFFNEDFVKAAGFTEAELMGQPHNIVRHPD
CCCCCCCEEEECCCCCCEEEEEECCCCCEEEEECHHHHHHCCCCHHHHCCCCCHHCCCCC
MPPEAFDNLWTTLKHGRPWVGAVKNRRKNGDYYWVLATASPIVQNGQVTGYTSVRTKLPS
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHCCCCCCCCHHHHHCCCC
DQRAEAEQVYAAIREKKPHGYKIEDGIVRRRSLFDHLAVFTGTIASRLRTLIGLQTLFLI
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGGMSLSAGGAGSMAAAGIAAAGIVLCGLVGLRTMNVIVGPLTHVNETMESITQGKLDT
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RMRIERDDEIGRALRNLQTVQTMVRFNARELKEQEQRAEVSRKQEMSKLAESFEGAIGNI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDTVSSASSELESSANSLSGTALRGQELSTTVAAASEEASANVQAVASATEELTSSVKEI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHH
SRQVQESARIASDAVDQARRTNDRVGELSKAATRIGDVVELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQISGIQAATQESVGAIREISTTIERLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAATVAAAVEEQGAATSEIARNIQHAAAGTQEVSSNIVDVQRGASETGETSGQVLTAAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QLSGDSQRLKQEVSRFLQSVRAA
HHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKNLPVTTVEYPITDDTLIVSKTDAKGKLTFFNEDFVKAAGFTEAELMGQPHNIVRHPD
CCCCCCCEEEECCCCCCEEEEEECCCCCEEEEECHHHHHHCCCCHHHHCCCCCHHCCCCC
MPPEAFDNLWTTLKHGRPWVGAVKNRRKNGDYYWVLATASPIVQNGQVTGYTSVRTKLPS
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHCCCCCCCCHHHHHCCCC
DQRAEAEQVYAAIREKKPHGYKIEDGIVRRRSLFDHLAVFTGTIASRLRTLIGLQTLFLI
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLGGMSLSAGGAGSMAAAGIAAAGIVLCGLVGLRTMNVIVGPLTHVNETMESITQGKLDT
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
RMRIERDDEIGRALRNLQTVQTMVRFNARELKEQEQRAEVSRKQEMSKLAESFEGAIGNI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDTVSSASSELESSANSLSGTALRGQELSTTVAAASEEASANVQAVASATEELTSSVKEI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHCHHHHHHHHHHHHHHHHHHH
SRQVQESARIASDAVDQARRTNDRVGELSKAATRIGDVVELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGEAGRGFAVVASEVKALAEQTAKATGEIGQQISGIQAATQESVGAIREISTTIERLS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAATVAAAVEEQGAATSEIARNIQHAAAGTQEVSSNIVDVQRGASETGETSGQVLTAAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QLSGDSQRLKQEVSRFLQSVRAA
HHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]