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The map label for this gene is yfhM [H]

Identifier: 146339524

GI number: 146339524

Start: 2688194

End: 2689198

Strand: Direct

Name: yfhM [H]

Synonym: BRADO2514

Alternate gene names: 146339524

Gene position: 2688194-2689198 (Clockwise)

Preceding gene: 146339523

Following gene: 146339526

Centisome position: 36.05

GC content: 67.36

Gene sequence:

>1005_bases
ATGACCGATCCGACATCGATGCCGCCGCTGCAATACGCGACCACCAATGGCATTCGGATGGGCTATTACGAGGCCGGTCC
TGCAACCGACCATCCGCCCATGATCCTCTGCCACGGCTGGCCGGAGCTGGCCTTTTCCTGGCGGCACCAGATCAAGGCGC
TGGCGGAGGCGGGCATCCGCGTCATCGCGCCGGACCAGCGCGGCTATGGCGCCACCGACCGGCCGGAGCCGGTCGAGTCC
TACGACCTCGAGCATCTCACAGCTGACCTGGTCGGGCTGCTCGATCATCTCGAGATCGACAAGGCGATCTTCGTCGGCCA
CGACTGGGGCGGATTCGTCGTCTGGCAGATGCCGCTGCGCCATCCGGACCGCGTCGCCGGCGTGGTCGGCATCAACACGC
CGCATCTGCCGCGCGCGCCCGCCGATCCCATTGCGATCATGCGCAAGCGCTTCGGTGAGATGATGTACATCGTCCAGTTC
CAGGACCCGGCCCGCGAGCCGGATCGGATTTTCGGCAGCCGCGTCGAGCAGACCTTCGACGCCTTCATGCGCAAGCCGCT
GCCGCGCGGCGACGCGCCGTCGACCGAGCCGCAGGCGGGCGGGATCGCGGCGTCGCCAACCCTGAACCTGGCCTTTCCGC
AGACGATCGCGGCCTATGACGCATCGAAGGACACGCGGCAGCCGATCTTGTCGGCGGCGGAGAAGCGCGTGTTCGTCGAG
ACGTTCTCGCGCACCGGCTTCACCGGCGGCATCAACTGGTATCGCAACATGACCCGCAACTGGCAGCGCTCCGAGGGGCT
CGACCACACGGTGCGGGTGCCGTCGCTGATGATCATGGCCGAGAACGACGCCGTGTTGCCGCCGTCGGCCGCCGACGGCA
TGGAGAAGCTGGTGCCGGACCTGGAGAAGTATCTCGTCCGCGACAGCGGCCATTGGACCCAGCAGGAGCAGCCCGAGGAG
GTCAGCGCCAAGCTGATCGAATGGCGGCGACGGAGGTTCGGGTAG

Upstream 100 bases:

>100_bases
AGCGACCGAGGCGTCTTCACGCCGCGTCATCGAGCGTGCACCATGCCGCCTGCCAGAACCGGGCAGCCAAGCCCGGCAGA
GCAGCTTCACGGGAGGACGC

Downstream 100 bases:

>100_bases
GGACGGGCCAGCTGGTTGACGGGCGAGGACATGAGATCGCTTGGTGAAAGCCAAAGGCCGAGCCCAACATTCGGGGTCGT
GCCGGACAAGCCTGCCGACG

Product: putative epoxide hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTDPTSMPPLQYATTNGIRMGYYEAGPATDHPPMILCHGWPELAFSWRHQIKALAEAGIRVIAPDQRGYGATDRPEPVES
YDLEHLTADLVGLLDHLEIDKAIFVGHDWGGFVVWQMPLRHPDRVAGVVGINTPHLPRAPADPIAIMRKRFGEMMYIVQF
QDPAREPDRIFGSRVEQTFDAFMRKPLPRGDAPSTEPQAGGIAASPTLNLAFPQTIAAYDASKDTRQPILSAAEKRVFVE
TFSRTGFTGGINWYRNMTRNWQRSEGLDHTVRVPSLMIMAENDAVLPPSAADGMEKLVPDLEKYLVRDSGHWTQQEQPEE
VSAKLIEWRRRRFG

Sequences:

>Translated_334_residues
MTDPTSMPPLQYATTNGIRMGYYEAGPATDHPPMILCHGWPELAFSWRHQIKALAEAGIRVIAPDQRGYGATDRPEPVES
YDLEHLTADLVGLLDHLEIDKAIFVGHDWGGFVVWQMPLRHPDRVAGVVGINTPHLPRAPADPIAIMRKRFGEMMYIVQF
QDPAREPDRIFGSRVEQTFDAFMRKPLPRGDAPSTEPQAGGIAASPTLNLAFPQTIAAYDASKDTRQPILSAAEKRVFVE
TFSRTGFTGGINWYRNMTRNWQRSEGLDHTVRVPSLMIMAENDAVLPPSAADGMEKLVPDLEKYLVRDSGHWTQQEQPEE
VSAKLIEWRRRRFG
>Mature_333_residues
TDPTSMPPLQYATTNGIRMGYYEAGPATDHPPMILCHGWPELAFSWRHQIKALAEAGIRVIAPDQRGYGATDRPEPVESY
DLEHLTADLVGLLDHLEIDKAIFVGHDWGGFVVWQMPLRHPDRVAGVVGINTPHLPRAPADPIAIMRKRFGEMMYIVQFQ
DPAREPDRIFGSRVEQTFDAFMRKPLPRGDAPSTEPQAGGIAASPTLNLAFPQTIAAYDASKDTRQPILSAAEKRVFVET
FSRTGFTGGINWYRNMTRNWQRSEGLDHTVRVPSLMIMAENDAVLPPSAADGMEKLVPDLEKYLVRDSGHWTQQEQPEEV
SAKLIEWRRRRFG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=315, Percent_Identity=34.9206349206349, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI218777837, Length=313, Percent_Identity=28.7539936102236, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI218777840, Length=311, Percent_Identity=26.0450160771704, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI13376164, Length=311, Percent_Identity=26.0450160771704, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17554012, Length=315, Percent_Identity=27.9365079365079, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17562298, Length=315, Percent_Identity=27.6190476190476, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324392, Length=321, Percent_Identity=22.4299065420561, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 37554; Mature: 37423

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPTSMPPLQYATTNGIRMGYYEAGPATDHPPMILCHGWPELAFSWRHQIKALAEAGIR
CCCCCCCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
VIAPDQRGYGATDRPEPVESYDLEHLTADLVGLLDHLEIDKAIFVGHDWGGFVVWQMPLR
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCC
HPDRVAGVVGINTPHLPRAPADPIAIMRKRFGEMMYIVQFQDPAREPDRIFGSRVEQTFD
CCCHHEEEEECCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AFMRKPLPRGDAPSTEPQAGGIAASPTLNLAFPQTIAAYDASKDTRQPILSAAEKRVFVE
HHHHCCCCCCCCCCCCCCCCCEECCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFSRTGFTGGINWYRNMTRNWQRSEGLDHTVRVPSLMIMAENDAVLPPSAADGMEKLVPD
HHHCCCCCCCHHHHHHHHCCCHHHCCCCCEEECCEEEEEECCCCCCCCCHHHHHHHHHHH
LEKYLVRDSGHWTQQEQPEEVSAKLIEWRRRRFG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDPTSMPPLQYATTNGIRMGYYEAGPATDHPPMILCHGWPELAFSWRHQIKALAEAGIR
CCCCCCCCCEEECCCCEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
VIAPDQRGYGATDRPEPVESYDLEHLTADLVGLLDHLEIDKAIFVGHDWGGFVVWQMPLR
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCC
HPDRVAGVVGINTPHLPRAPADPIAIMRKRFGEMMYIVQFQDPAREPDRIFGSRVEQTFD
CCCHHEEEEECCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHH
AFMRKPLPRGDAPSTEPQAGGIAASPTLNLAFPQTIAAYDASKDTRQPILSAAEKRVFVE
HHHHCCCCCCCCCCCCCCCCCEECCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
TFSRTGFTGGINWYRNMTRNWQRSEGLDHTVRVPSLMIMAENDAVLPPSAADGMEKLVPD
HHHCCCCCCCHHHHHHHHCCCHHHCCCCCEEECCEEEEEECCCCCCCCCHHHHHHHHHHH
LEKYLVRDSGHWTQQEQPEEVSAKLIEWRRRRFG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]