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The map label for this gene is guaB [C]

Identifier: 146339451

GI number: 146339451

Start: 2597923

End: 2598348

Strand: Direct

Name: guaB [C]

Synonym: BRADO2437

Alternate gene names: 146339451

Gene position: 2597923-2598348 (Clockwise)

Preceding gene: 146339450

Following gene: 146339452

Centisome position: 34.84

GC content: 62.21

Gene sequence:

>426_bases
TTGTACAAATTTCTCGAGGACACCGCTGGCAGCTACATGACGCGGACCATCACCACCGTGACCCGCGAGACGACGATTCG
CGAGCTCGGCGAGATGTTCGACCGCGACGATTTCAACACCTACCCCGTCGTCGAGAACGACGAGGTCATCGGCATCGTCA
CCAAGTTCGATGTGTTGAAGTGCTTCGCCTTCACGCCCAACCAGATGCTGCCGCGCTACAGCGACCTGATGAACCGGACG
GTTGCCGATGTGATGACGTCCGAGTTCATCTATGTCAGGCCCGACACCAAGCTGACGCGCGTGCTGCAGCTGATGGTCGA
GCACCGCATCCGCAGCCTTCCCGTGACCGACGGCGACAACCGCCTGGTCGGCATCATCGCCCGCGAGGACATCGTGCGGG
CGCTCGCGGCGGCCGCCAAGGACTGA

Upstream 100 bases:

>100_bases
GCTGGGCGGCGTCACCGAGCATCTCGTGACACGCGCCGATCGCTGCGTGCTGCTGTCGCACTGAATTTCAACCGCTCCAT
CCGAGAACAGGATTGCCGCC

Downstream 100 bases:

>100_bases
CGGCGGACAGACGCCGCGCGCGGCCTCAACTGATACGGAAGTCTAAGACCGACATCGTCCCGTACGCTCTCAGCGTGCGG
GACGATGTGCTTGCGCGGTC

Product: hypothetical protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MYKFLEDTAGSYMTRTITTVTRETTIRELGEMFDRDDFNTYPVVENDEVIGIVTKFDVLKCFAFTPNQMLPRYSDLMNRT
VADVMTSEFIYVRPDTKLTRVLQLMVEHRIRSLPVTDGDNRLVGIIAREDIVRALAAAAKD

Sequences:

>Translated_141_residues
MYKFLEDTAGSYMTRTITTVTRETTIRELGEMFDRDDFNTYPVVENDEVIGIVTKFDVLKCFAFTPNQMLPRYSDLMNRT
VADVMTSEFIYVRPDTKLTRVLQLMVEHRIRSLPVTDGDNRLVGIIAREDIVRALAAAAKD
>Mature_141_residues
MYKFLEDTAGSYMTRTITTVTRETTIRELGEMFDRDDFNTYPVVENDEVIGIVTKFDVLKCFAFTPNQMLPRYSDLMNRT
VADVMTSEFIYVRPDTKLTRVLQLMVEHRIRSLPVTDGDNRLVGIIAREDIVRALAAAAKD

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: COG0517

COG function: function code R; FOG: CBS domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR003115
- InterPro:   IPR016427 [H]

Pfam domain/function: PF00571 CBS; PF02195 ParBc [H]

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 16207; Mature: 16207

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFLEDTAGSYMTRTITTVTRETTIRELGEMFDRDDFNTYPVVENDEVIGIVTKFDVLK
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHH
CFAFTPNQMLPRYSDLMNRTVADVMTSEFIYVRPDTKLTRVLQLMVEHRIRSLPVTDGDN
HHHCCCHHHCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
RLVGIIAREDIVRALAAAAKD
CEEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYKFLEDTAGSYMTRTITTVTRETTIRELGEMFDRDDFNTYPVVENDEVIGIVTKFDVLK
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHH
CFAFTPNQMLPRYSDLMNRTVADVMTSEFIYVRPDTKLTRVLQLMVEHRIRSLPVTDGDN
HHHCCCHHHCHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
RLVGIIAREDIVRALAAAAKD
CEEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]