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The map label for this gene is tftE [H]

Identifier: 146339289

GI number: 146339289

Start: 2413624

End: 2414694

Strand: Direct

Name: tftE [H]

Synonym: BRADO2265

Alternate gene names: 146339289

Gene position: 2413624-2414694 (Clockwise)

Preceding gene: 146339288

Following gene: 146339290

Centisome position: 32.37

GC content: 69.09

Gene sequence:

>1071_bases
ATGACCAGCATACGGGCGTTCATCTTCCCGGGCATCCGCTCGCGCGTCGTGTTCGGCGCGGGTACGCTGTCGCAGCTCGT
CCCCGAGATGGAGCGGCTCGGCCGCAAGCGTGCGTTGCTGTTGGCGACGCCGCAGCAACGCATGGACATCGATGCGCTCG
CCGACCGGCTCGGCAGCGCGTCCGCCGGCGTGTTTGCCGGCGCTGTCATGCACACTCCGGTCGACGTTACGCGCGAGGCC
GTGGCGGCCTACGCGCAGAGCGGGGCGGATTGCGTGATTGCGCTCGGCGGCGGCTCGTCGATTGGGCTCGGCAAGGCGAT
CGCGCTGCGCACCGGGGCCGATCAGATCGCCGTCCCGACCACCTATGCCGGCTCCGAGATGACCGACATCCTCGGCGAGA
CCAGCGGCGGCGAGAAGACCACCCGGCGCGATCCGGCGATCCTGCCGGAGACGGTGATCTACGACGTCGACCTGTCGCTG
ACCTTGCCGAAGGACATGACGGTCTCGTCGGGCCTGAACGCGATCGCGCATGCGGCCGAGGCGCTGTATGCGCCGGATCG
CAATCCGATCCTGTCGCTGATGGCGGCTGATGCGATCAGGTCGTTTGCGACAGCCTTGCCCGCCGTGATCGCGAACCTCT
CCGACAAGAACGCTCGCGCCGATGCGCTGTACGGCGCATGGCTGTGCGGCGCGACCCTTGGCGGCGCCTCGATGTCCTTG
CATCACAAGCTCTGCCACACGCTGGGCGGCAGCTTCGACACGCCGCATGCGCAGACGCATGCGATCCTGCTGCCGCACAC
GATCGGCTTCAACGTGGCGGTCGCCGGCGATCTGCTGGCGCCGCTCTCCGCGGCCCTCGGCGGAGCAACGCCCGGCAAGG
CGCTGCACCGTTTTGCGACGCAGCTCGGCGCGCCCACGCGGCTGAAGGATCTCGGCCTGACCGAACCCGATCTCGATCGG
GCCGCCGCGATCGCGGTCAAGAACCCCTATGCCAATCCGCGGTCGTTCAGCCAGGCTGACATCCGCGCGCTGCTGCGGGA
CGCCTGGGCCGGCACAGAACCACCGCTCTAG

Upstream 100 bases:

>100_bases
GCCTGCTCGCCGACTTCAAGCCGACGCGACGCAAGGACGTGCCCTGGAGCCTCACCTACACCTTCGTCATGGCGCGCGCG
CCGAAGACGCGGAGCACCAC

Downstream 100 bases:

>100_bases
AACGATCGTTGACTTAAAAAATATCAGGGAGAGAACGAGACATGATTACGCGACGAAGGCTTCTCGAAACGGCCGCCGCG
GGCGGCCTGCTGACGGCGAC

Product: maleylacetate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTSIRAFIFPGIRSRVVFGAGTLSQLVPEMERLGRKRALLLATPQQRMDIDALADRLGSASAGVFAGAVMHTPVDVTREA
VAAYAQSGADCVIALGGGSSIGLGKAIALRTGADQIAVPTTYAGSEMTDILGETSGGEKTTRRDPAILPETVIYDVDLSL
TLPKDMTVSSGLNAIAHAAEALYAPDRNPILSLMAADAIRSFATALPAVIANLSDKNARADALYGAWLCGATLGGASMSL
HHKLCHTLGGSFDTPHAQTHAILLPHTIGFNVAVAGDLLAPLSAALGGATPGKALHRFATQLGAPTRLKDLGLTEPDLDR
AAAIAVKNPYANPRSFSQADIRALLRDAWAGTEPPL

Sequences:

>Translated_356_residues
MTSIRAFIFPGIRSRVVFGAGTLSQLVPEMERLGRKRALLLATPQQRMDIDALADRLGSASAGVFAGAVMHTPVDVTREA
VAAYAQSGADCVIALGGGSSIGLGKAIALRTGADQIAVPTTYAGSEMTDILGETSGGEKTTRRDPAILPETVIYDVDLSL
TLPKDMTVSSGLNAIAHAAEALYAPDRNPILSLMAADAIRSFATALPAVIANLSDKNARADALYGAWLCGATLGGASMSL
HHKLCHTLGGSFDTPHAQTHAILLPHTIGFNVAVAGDLLAPLSAALGGATPGKALHRFATQLGAPTRLKDLGLTEPDLDR
AAAIAVKNPYANPRSFSQADIRALLRDAWAGTEPPL
>Mature_355_residues
TSIRAFIFPGIRSRVVFGAGTLSQLVPEMERLGRKRALLLATPQQRMDIDALADRLGSASAGVFAGAVMHTPVDVTREAV
AAYAQSGADCVIALGGGSSIGLGKAIALRTGADQIAVPTTYAGSEMTDILGETSGGEKTTRRDPAILPETVIYDVDLSLT
LPKDMTVSSGLNAIAHAAEALYAPDRNPILSLMAADAIRSFATALPAVIANLSDKNARADALYGAWLCGATLGGASMSLH
HKLCHTLGGSFDTPHAQTHAILLPHTIGFNVAVAGDLLAPLSAALGGATPGKALHRFATQLGAPTRLKDLGLTEPDLDRA
AAIAVKNPYANPRSFSQADIRALLRDAWAGTEPPL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI48994951, Length=389, Percent_Identity=29.0488431876607, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=26.0053619302949, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082107, Length=293, Percent_Identity=28.6689419795222, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787493, Length=410, Percent_Identity=24.8780487804878, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=424, Percent_Identity=22.6415094339623, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321181, Length=390, Percent_Identity=26.4102564102564, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.3.1.32 [H]

Molecular weight: Translated: 36872; Mature: 36740

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIRAFIFPGIRSRVVFGAGTLSQLVPEMERLGRKRALLLATPQQRMDIDALADRLGSA
CCCCCCEECCCCHHEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHCCC
SAGVFAGAVMHTPVDVTREAVAAYAQSGADCVIALGGGSSIGLGKAIALRTGADQIAVPT
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCEECCC
TYAGSEMTDILGETSGGEKTTRRDPAILPETVIYDVDLSLTLPKDMTVSSGLNAIAHAAE
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECEEEECCCCCCHHHHHHHHHHHHH
ALYAPDRNPILSLMAADAIRSFATALPAVIANLSDKNARADALYGAWLCGATLGGASMSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
HHKLCHTLGGSFDTPHAQTHAILLPHTIGFNVAVAGDLLAPLSAALGGATPGKALHRFAT
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHH
QLGAPTRLKDLGLTEPDLDRAAAIAVKNPYANPRSFSQADIRALLRDAWAGTEPPL
HHCCCCCHHHCCCCCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSIRAFIFPGIRSRVVFGAGTLSQLVPEMERLGRKRALLLATPQQRMDIDALADRLGSA
CCCCCEECCCCHHEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHCCC
SAGVFAGAVMHTPVDVTREAVAAYAQSGADCVIALGGGSSIGLGKAIALRTGADQIAVPT
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCEECCC
TYAGSEMTDILGETSGGEKTTRRDPAILPETVIYDVDLSLTLPKDMTVSSGLNAIAHAAE
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECEEEECCCCCCHHHHHHHHHHHHH
ALYAPDRNPILSLMAADAIRSFATALPAVIANLSDKNARADALYGAWLCGATLGGASMSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
HHKLCHTLGGSFDTPHAQTHAILLPHTIGFNVAVAGDLLAPLSAALGGATPGKALHRFAT
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHH
QLGAPTRLKDLGLTEPDLDRAAAIAVKNPYANPRSFSQADIRALLRDAWAGTEPPL
HHCCCCCHHHCCCCCCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7538273 [H]