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The map label for this gene is ytfL [C]

Identifier: 146337817

GI number: 146337817

Start: 734425

End: 735735

Strand: Reverse

Name: ytfL [C]

Synonym: BRADO0697

Alternate gene names: 146337817

Gene position: 735735-734425 (Counterclockwise)

Preceding gene: 146337818

Following gene: 146337816

Centisome position: 9.87

GC content: 68.5

Gene sequence:

>1311_bases
ATGCTGTCCGCCGAACTCGCCATCATCGTCGTCCTCATCGTCGTCAACGGACTGTTATCCATGTCCGAGCTGGCCATCGT
GTCGTCGCGCCCCGCACGGCTGGCGCTATTGGCTGAAAAGGGCGTGTCCGGCGCGCGGCGGGCGCTGGCGCTGGCCTCGG
ATCCCGGCCGTTTCCTGTCGACGGTGCAGATCGGCATCACGCTCGTCGGCGTGCTCTCCGGCGCCTTCTCCGGCGCCACG
CTCGGCCAGCGCCTGACCCAATCGCTGCTGGAGATGGGAATGTCGGCCTCGGTCGCCGACATTGTCGGCGTCGGCCTCGT
CGTCACCATCATCACCTATGCGACGCTGATCGTCGGCGAGCTGGTGCCGAAGCAGCTCGCGCTGCGCGATCCCGAGGCGA
TCGCGGTGCGCGTCGCGCCGGCGATGCAGGTGCTGGCCAAGGTGTCGCTGCCGCTCGTGGTGCTGCTGGATCTCTCGGGC
AAGCTGATCCTGGCGCTGCTCGGCCGCTCCGGCGAGGCCGAGGAGAAGGTCTCGGAGGCCGAGATTCACCATCTTGTCCG
CGAGGCCGAAACCGCCGGCGTGCTCGAGCCGGGCGAGAAGGAGATGATCGCCGGCGTGATGCGGCTCGGCGACCGCCCGG
TCGGCGCCATCATGACGCCACGCCCGGAGGTCGACGTCGTCGACCTCAACGACGACCCGAAGGCCATCCGCGAGCTGCTC
GCCAAGAGCCCACATTCCCGCCTGCCCGTGTCCGACGGCGAGCGCGACCGTCCGATCGGCGTGCTGCAGGCGAAGGACCT
GCTGGCGGCCTATTTGCGTGACGAGACGCCGGACCTGCGCAGCCTGGTGCGCGAAGTGCCGATCATTCCGTCCACGGTCG
ATGCGCGCGATGTGATCGCGATCCTGAAGGTGGCGCCGGTGCATATGGGCCTCGTCCACGATGAGTATGGCGCGTTCGAA
GGCGTCGTGACCGCAGCGGACATTCTCGAATCGATCGTCGGCGCGTTCTCCTCGGAGGAAGGCCCGCCAGAACCGGCCTG
CGTCCGCCGCGACGACGGCTCGCTGCTGGTCTCCGGCTGGATGCCGCTCGACGAGTTTGCCGACCTGCTGTCGATCGACG
TGCCGCCGCATCGCGGCTACCACACAGTCGCCGGCCTCGTGCTGCAGCACTTCGGCAGCGTGCCGGAGGTCGGCCAGAGC
TTCGAGCTCGACGGCTGGCGCTTCGAGATCGTCGACCTCGACGGCCGCCGCATCGACAAGATTCTGGCGACCAAGCTCGC
GCCCGACGGCGGCGAGCCGAATGTAGGATAG

Upstream 100 bases:

>100_bases
GGTCCCCATGCGCCCACCGCAACGCAGCAATGGGCGGCTGCCATCCCCATATGCTAGGACCTGTCCCTTCCCGCCCGTCC
GGGCGTCACATCAGGTCGCA

Downstream 100 bases:

>100_bases
CGGGACTATCGCATCTGGGGATCCAAGTTTGCGCTTGCCTGTCTCCACGTCGTCCTGGCCGGGCTTGTCCCGGCCATCCA
CGTCGTTCGGCATGCTGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLSAELAIIVVLIVVNGLLSMSELAIVSSRPARLALLAEKGVSGARRALALASDPGRFLSTVQIGITLVGVLSGAFSGAT
LGQRLTQSLLEMGMSASVADIVGVGLVVTIITYATLIVGELVPKQLALRDPEAIAVRVAPAMQVLAKVSLPLVVLLDLSG
KLILALLGRSGEAEEKVSEAEIHHLVREAETAGVLEPGEKEMIAGVMRLGDRPVGAIMTPRPEVDVVDLNDDPKAIRELL
AKSPHSRLPVSDGERDRPIGVLQAKDLLAAYLRDETPDLRSLVREVPIIPSTVDARDVIAILKVAPVHMGLVHDEYGAFE
GVVTAADILESIVGAFSSEEGPPEPACVRRDDGSLLVSGWMPLDEFADLLSIDVPPHRGYHTVAGLVLQHFGSVPEVGQS
FELDGWRFEIVDLDGRRIDKILATKLAPDGGEPNVG

Sequences:

>Translated_436_residues
MLSAELAIIVVLIVVNGLLSMSELAIVSSRPARLALLAEKGVSGARRALALASDPGRFLSTVQIGITLVGVLSGAFSGAT
LGQRLTQSLLEMGMSASVADIVGVGLVVTIITYATLIVGELVPKQLALRDPEAIAVRVAPAMQVLAKVSLPLVVLLDLSG
KLILALLGRSGEAEEKVSEAEIHHLVREAETAGVLEPGEKEMIAGVMRLGDRPVGAIMTPRPEVDVVDLNDDPKAIRELL
AKSPHSRLPVSDGERDRPIGVLQAKDLLAAYLRDETPDLRSLVREVPIIPSTVDARDVIAILKVAPVHMGLVHDEYGAFE
GVVTAADILESIVGAFSSEEGPPEPACVRRDDGSLLVSGWMPLDEFADLLSIDVPPHRGYHTVAGLVLQHFGSVPEVGQS
FELDGWRFEIVDLDGRRIDKILATKLAPDGGEPNVG
>Mature_436_residues
MLSAELAIIVVLIVVNGLLSMSELAIVSSRPARLALLAEKGVSGARRALALASDPGRFLSTVQIGITLVGVLSGAFSGAT
LGQRLTQSLLEMGMSASVADIVGVGLVVTIITYATLIVGELVPKQLALRDPEAIAVRVAPAMQVLAKVSLPLVVLLDLSG
KLILALLGRSGEAEEKVSEAEIHHLVREAETAGVLEPGEKEMIAGVMRLGDRPVGAIMTPRPEVDVVDLNDDPKAIRELL
AKSPHSRLPVSDGERDRPIGVLQAKDLLAAYLRDETPDLRSLVREVPIIPSTVDARDVIAILKVAPVHMGLVHDEYGAFE
GVVTAADILESIVGAFSSEEGPPEPACVRRDDGSLLVSGWMPLDEFADLLSIDVPPHRGYHTVAGLVLQHFGSVPEVGQS
FELDGWRFEIVDLDGRRIDKILATKLAPDGGEPNVG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=375, Percent_Identity=25.6, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1790664, Length=429, Percent_Identity=30.5361305361305, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI87082033, Length=264, Percent_Identity=30.6818181818182, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI145693175, Length=420, Percent_Identity=26.1904761904762, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1788119, Length=241, Percent_Identity=32.7800829875519, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=27.6679841897233, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46184; Mature: 46184

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAELAIIVVLIVVNGLLSMSELAIVSSRPARLALLAEKGVSGARRALALASDPGRFLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHEEECCCCCHHHH
TVQIGITLVGVLSGAFSGATLGQRLTQSLLEMGMSASVADIVGVGLVVTIITYATLIVGE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVPKQLALRDPEAIAVRVAPAMQVLAKVSLPLVVLLDLSGKLILALLGRSGEAEEKVSEA
HHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCEEHHHHCCCCCHHHHHHHH
EIHHLVREAETAGVLEPGEKEMIAGVMRLGDRPVGAIMTPRPEVDVVDLNDDPKAIRELL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCHHHHHHHH
AKSPHSRLPVSDGERDRPIGVLQAKDLLAAYLRDETPDLRSLVREVPIIPSTVDARDVIA
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHH
ILKVAPVHMGLVHDEYGAFEGVVTAADILESIVGAFSSEEGPPEPACVRRDDGSLLVSGW
HHHHHHHHHCEEECHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECC
MPLDEFADLLSIDVPPHRGYHTVAGLVLQHFGSVPEVGQSFELDGWRFEIVDLDGRRIDK
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHH
ILATKLAPDGGEPNVG
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLSAELAIIVVLIVVNGLLSMSELAIVSSRPARLALLAEKGVSGARRALALASDPGRFLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHEEECCCCCHHHH
TVQIGITLVGVLSGAFSGATLGQRLTQSLLEMGMSASVADIVGVGLVVTIITYATLIVGE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LVPKQLALRDPEAIAVRVAPAMQVLAKVSLPLVVLLDLSGKLILALLGRSGEAEEKVSEA
HHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCEEHHHHCCCCCHHHHHHHH
EIHHLVREAETAGVLEPGEKEMIAGVMRLGDRPVGAIMTPRPEVDVVDLNDDPKAIRELL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCHHHHHHHH
AKSPHSRLPVSDGERDRPIGVLQAKDLLAAYLRDETPDLRSLVREVPIIPSTVDARDVIA
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHH
ILKVAPVHMGLVHDEYGAFEGVVTAADILESIVGAFSSEEGPPEPACVRRDDGSLLVSGW
HHHHHHHHHCEEECHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECC
MPLDEFADLLSIDVPPHRGYHTVAGLVLQHFGSVPEVGQSFELDGWRFEIVDLDGRRIDK
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHH
ILATKLAPDGGEPNVG
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]