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The map label for this gene is appC [H]

Identifier: 146337752

GI number: 146337752

Start: 651367

End: 652206

Strand: Direct

Name: appC [H]

Synonym: BRADO0627

Alternate gene names: 146337752

Gene position: 651367-652206 (Clockwise)

Preceding gene: 146337751

Following gene: 146337753

Centisome position: 8.74

GC content: 66.43

Gene sequence:

>840_bases
ATGAGGCAGTTCTGGCGCACCATGCTGCGCAGCCCGAGCGGCATCATCGGGCTGATCATCCTGATCCTTGCGATCGTGAT
CGCGGTGGCCGGACCGTTCTATTTCCCCAATTCCCCGTGGCGCATGGTGCAGCGGCCCTTCGTGCCGCCCTTCACCTTGG
CGAAGGTGCCGCTGGGGACCGATGCGCTCGGGCGCGACGTGCTGGCCGGCCTGATCTTCGGTGCCCGCGTCTCACTGCTG
GTCGGCCTGGTGTCGACGCTGGTCGCTCTCGTCGTCGGCGTGCCCCTTGGAGCGATCGCGGGGTACTTCGGCGGCCGCGT
CGACGATGCGCTGATGCGCTTCACGGAATTCTTTCAGACCATCCCGAGCTTCGCGCTGGCCATCGTGCTGGTCGCGATTC
TTCAGCCCTCGATTTATTCGATCGTCGCCGCCATCGGCCTCGTCAGCTGGCCGCCGGTGGCGCGCCTCGTACGCGGCGAG
GTGCTCTCCCTGCGCACCCGTGAATACGTCCAGGCGGCGATCGTCACCGGCCAGAGCAATGCCTGGATCATCTGGCGCGA
GATCCTGCCCAACGCGCTGTCGCCCGTGATCGTGCTGGCATCGCTGATGGTCGCGACGGCGATCCTCCTCGAATCCTCGC
TGTCGTTCCTCGGCCTCGGCGATCCCAATCTGATCTCCTGGGGCTACATGGTCGGCGCCGGCCGTACCGTCATCCGCCAG
GCCTGGTGGATCACGGTATTTCCGGGCGTGGCGATCCTGCTCGCCGTGCTCGGTCTCAACCTGATCGGCGAGGGCCTGAA
CGATGCGTTGAACCCGCGCCTGTCGCGGGAAGGCAGGTGA

Upstream 100 bases:

>100_bases
TGCTTGGCGTGTTCGTGGTCTCCTCGGCCATGGTGCTGATCTTCAACCTGGTCACCGACCTCGTCTATCGCCTGGTCGAC
CCGCGCATCGAGTATGCGTC

Downstream 100 bases:

>100_bases
GTGATGGCTGATAACAACTGCCGTAGGGTGGGCAAAGCGAAGCGTGCCCACCGATTGCCGATCTCGTCTGCCGATGGTGG
GCACGGCGCGGGCTGGAGCG

Product: putative dipeptide transport system permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRQFWRTMLRSPSGIIGLIILILAIVIAVAGPFYFPNSPWRMVQRPFVPPFTLAKVPLGTDALGRDVLAGLIFGARVSLL
VGLVSTLVALVVGVPLGAIAGYFGGRVDDALMRFTEFFQTIPSFALAIVLVAILQPSIYSIVAAIGLVSWPPVARLVRGE
VLSLRTREYVQAAIVTGQSNAWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLISWGYMVGAGRTVIRQ
AWWITVFPGVAILLAVLGLNLIGEGLNDALNPRLSREGR

Sequences:

>Translated_279_residues
MRQFWRTMLRSPSGIIGLIILILAIVIAVAGPFYFPNSPWRMVQRPFVPPFTLAKVPLGTDALGRDVLAGLIFGARVSLL
VGLVSTLVALVVGVPLGAIAGYFGGRVDDALMRFTEFFQTIPSFALAIVLVAILQPSIYSIVAAIGLVSWPPVARLVRGE
VLSLRTREYVQAAIVTGQSNAWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLISWGYMVGAGRTVIRQ
AWWITVFPGVAILLAVLGLNLIGEGLNDALNPRLSREGR
>Mature_279_residues
MRQFWRTMLRSPSGIIGLIILILAIVIAVAGPFYFPNSPWRMVQRPFVPPFTLAKVPLGTDALGRDVLAGLIFGARVSLL
VGLVSTLVALVVGVPLGAIAGYFGGRVDDALMRFTEFFQTIPSFALAIVLVAILQPSIYSIVAAIGLVSWPPVARLVRGE
VLSLRTREYVQAAIVTGQSNAWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLISWGYMVGAGRTVIRQ
AWWITVFPGVAILLAVLGLNLIGEGLNDALNPRLSREGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=243, Percent_Identity=39.917695473251, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=33.4545454545455, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=38.0782918149466, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=40.6360424028269, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788505, Length=236, Percent_Identity=37.7118644067797, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789889, Length=225, Percent_Identity=35.5555555555556, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787549, Length=279, Percent_Identity=31.5412186379928, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30037; Mature: 30037

Theoretical pI: Translated: 11.12; Mature: 11.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]