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The map label for this gene is nudG [H]

Identifier: 146337716

GI number: 146337716

Start: 599422

End: 599832

Strand: Reverse

Name: nudG [H]

Synonym: BRADO0585

Alternate gene names: 146337716

Gene position: 599832-599422 (Counterclockwise)

Preceding gene: 146337719

Following gene: 146337714

Centisome position: 8.04

GC content: 65.45

Gene sequence:

>411_bases
ATGACCGATTTCAAACTCACGCTCGTCGTCGCCTGCGCTCTGGTCGACACCGACAATCGCGTGCTGCTGGCGCAGCGGCC
GCCCGGCAAGACGCTCGCCGGCTTGTGGGAATTTCCTGGCGGCAAGCTCGAACCGGGCGAGCGTCCGGAGGCCAGCCTGA
TCCGCGAGCTCGACGAGGAGCTCGGCATCACCGTGCGCGAGACCTGCCTGGCGCCGCTGACCTTCGCCAGTCACGCCTAT
GAGACGTTCCACCTGCTGATGCCGCTTTACATCTGCCGGCGCTGGGAAGGCGTGGTGACCGCGCGCGAGGGCCAGAAATT
GGCCTGGGTGCGACCGAACAAGCTGCGCGACTACCCGATGCCGCCGGCGGACATTCCGCTGCTGCCGCATTTGATCGATC
TATTGATGTGA

Upstream 100 bases:

>100_bases
ATCGGGTTCCATAAGGTTCCATTGAGTTCCACCATGTTTGCGGCGCGGGCACGAATGGGTTAACGCTGAGTAAACCGCCC
TTCCCGCCCGACTGCATCAG

Downstream 100 bases:

>100_bases
GGCCGGGGGCGTCACGCCCCGCCTCGTCATGCGCGGGCTTGACCCGCCTGCGGGGCCGTAGCCCCTTCGGCGCGGCGAAG
GCCCGCGCATCCATCCTCTT

Product: putative mutator protein mutT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTDFKLTLVVACALVDTDNRVLLAQRPPGKTLAGLWEFPGGKLEPGERPEASLIRELDEELGITVRETCLAPLTFASHAY
ETFHLLMPLYICRRWEGVVTAREGQKLAWVRPNKLRDYPMPPADIPLLPHLIDLLM

Sequences:

>Translated_136_residues
MTDFKLTLVVACALVDTDNRVLLAQRPPGKTLAGLWEFPGGKLEPGERPEASLIRELDEELGITVRETCLAPLTFASHAY
ETFHLLMPLYICRRWEGVVTAREGQKLAWVRPNKLRDYPMPPADIPLLPHLIDLLM
>Mature_135_residues
TDFKLTLVVACALVDTDNRVLLAQRPPGKTLAGLWEFPGGKLEPGERPEASLIRELDEELGITVRETCLAPLTFASHAYE
TFHLLMPLYICRRWEGVVTAREGQKLAWVRPNKLRDYPMPPADIPLLPHLIDLLM

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=135, Percent_Identity=42.962962962963, Blast_Score=93, Evalue=7e-21,
Organism=Escherichia coli, GI1786288, Length=127, Percent_Identity=33.8582677165354, Blast_Score=73, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15360; Mature: 15229

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFKLTLVVACALVDTDNRVLLAQRPPGKTLAGLWEFPGGKLEPGERPEASLIRELDEE
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGITVRETCLAPLTFASHAYETFHLLMPLYICRRWEGVVTAREGQKLAWVRPNKLRDYPM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCC
PPADIPLLPHLIDLLM
CCCCCCHHHHHHHHHC
>Mature Secondary Structure 
TDFKLTLVVACALVDTDNRVLLAQRPPGKTLAGLWEFPGGKLEPGERPEASLIRELDEE
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LGITVRETCLAPLTFASHAYETFHLLMPLYICRRWEGVVTAREGQKLAWVRPNKLRDYPM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCC
PPADIPLLPHLIDLLM
CCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]