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The map label for this gene is ubiG

Identifier: 146337707

GI number: 146337707

Start: 592981

End: 593742

Strand: Direct

Name: ubiG

Synonym: BRADO0576

Alternate gene names: 146337707

Gene position: 592981-593742 (Clockwise)

Preceding gene: 146337706

Following gene: 146337709

Centisome position: 7.95

GC content: 64.7

Gene sequence:

>762_bases
ATGACAATGTCTCAGGATTCCCGCAGTACGCCCGGCTCGACGGTCGATCCGGCCGAGATTGCGAAATTCTCCAAACTGTC
GGAGACCTGGTGGGACCCCAAGGGCAAGATGGCGCCCTTGCACAAGATCAACCCGCTGCGCCTGACCTATATCCGCGACG
CCGCCTGCCGGAAGTTCGAGCGCAACGCCAAGAGCCTCAACTGCCTGTCGGGTCTGCGCATGCTCGACATCGGCTGCGGC
GCCGGCCTGTTGTGCGAGCCGTTCACGCGCCTCGGCGCGCAGGTCGTCGGCGTCGATCCCTCCGCGAGCAACATCGCCGC
CGCCAAGCTGCACGCCGAGAAGGGCCATATGTCGATCGACTACCGCTGCACGACCATCGAAGAGATGGATCCGCGCGAGC
GCTTCGACATCGTGCTGGCGATGGAGGTCGTCGAGCACGTCACCGATGTCGGCGCCTTCCTCGGCCGCTGCGCCGCCGTG
CTGAAGCCGGGCGGCCTGATGGTGGTCTCGACCCTGAACCGCAACTGGAAGAGCTTCGCGCTCGCCATCGTCGGCGCCGA
ATATGTCCTGCGCTGGCTGCCGCGCGGGACGCATGAATGGAGCAAGTTCGTCACTCCCGACGAGCTGACCAAATATCTCC
TCGACAACCGCCTCGTCATCACCGAGCAGAGCGGCGTCGTCTACAGCCCGTTCGCCGACCGCTGGAGCCTGTCCAGCGAC
ATGGACGTGAACTACATGGTGGTCGCCGAGCAGATGGTCTGA

Upstream 100 bases:

>100_bases
GAAACCATTTCGACCATCGCGGAGCCGCTGGCGTTTCGCAACGCCATCACGGCGCGATAGCCCGCCCGGACGGTCCAGCT
TCGATCATGAGTATGCAGCG

Downstream 100 bases:

>100_bases
TCAGCTCTGACTTGGATCGTCTGCCGCTCCATATACGGTGTCGTCCCTGCGAACGCAGGGACCCATAACCACAGGGAGGG
GTTAGGGGCACGCTAGGAGA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTMSQDSRSTPGSTVDPAEIAKFSKLSETWWDPKGKMAPLHKINPLRLTYIRDAACRKFERNAKSLNCLSGLRMLDIGCG
AGLLCEPFTRLGAQVVGVDPSASNIAAAKLHAEKGHMSIDYRCTTIEEMDPRERFDIVLAMEVVEHVTDVGAFLGRCAAV
LKPGGLMVVSTLNRNWKSFALAIVGAEYVLRWLPRGTHEWSKFVTPDELTKYLLDNRLVITEQSGVVYSPFADRWSLSSD
MDVNYMVVAEQMV

Sequences:

>Translated_253_residues
MTMSQDSRSTPGSTVDPAEIAKFSKLSETWWDPKGKMAPLHKINPLRLTYIRDAACRKFERNAKSLNCLSGLRMLDIGCG
AGLLCEPFTRLGAQVVGVDPSASNIAAAKLHAEKGHMSIDYRCTTIEEMDPRERFDIVLAMEVVEHVTDVGAFLGRCAAV
LKPGGLMVVSTLNRNWKSFALAIVGAEYVLRWLPRGTHEWSKFVTPDELTKYLLDNRLVITEQSGVVYSPFADRWSLSSD
MDVNYMVVAEQMV
>Mature_252_residues
TMSQDSRSTPGSTVDPAEIAKFSKLSETWWDPKGKMAPLHKINPLRLTYIRDAACRKFERNAKSLNCLSGLRMLDIGCGA
GLLCEPFTRLGAQVVGVDPSASNIAAAKLHAEKGHMSIDYRCTTIEEMDPRERFDIVLAMEVVEHVTDVGAFLGRCAAVL
KPGGLMVVSTLNRNWKSFALAIVGAEYVLRWLPRGTHEWSKFVTPDELTKYLLDNRLVITEQSGVVYSPFADRWSLSSDM
DVNYMVVAEQMV

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=246, Percent_Identity=41.869918699187, Blast_Score=201, Evalue=4e-52,
Organism=Escherichia coli, GI1788564, Length=243, Percent_Identity=40.7407407407407, Blast_Score=192, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI115533050, Length=246, Percent_Identity=32.9268292682927, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324476, Length=275, Percent_Identity=29.4545454545455, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281365311, Length=240, Percent_Identity=31.25, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24585589, Length=241, Percent_Identity=30.7053941908714, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_BRASO (A4YKT6)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001202755.1
- ProteinModelPortal:   A4YKT6
- STRING:   A4YKT6
- GeneID:   5115336
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO0576
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   KFITPDE
- ProtClustDB:   PRK05134
- BioCyc:   BSP376:BRADO0576-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 28147; Mature: 28016

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSQDSRSTPGSTVDPAEIAKFSKLSETWWDPKGKMAPLHKINPLRLTYIRDAACRKFE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHH
RNAKSLNCLSGLRMLDIGCGAGLLCEPFTRLGAQVVGVDPSASNIAAAKLHAEKGHMSID
HCCHHHHHHHCCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCEEEE
YRCTTIEEMDPRERFDIVLAMEVVEHVTDVGAFLGRCAAVLKPGGLMVVSTLNRNWKSFA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LAIVGAEYVLRWLPRGTHEWSKFVTPDELTKYLLDNRLVITEQSGVVYSPFADRWSLSSD
HHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCC
MDVNYMVVAEQMV
CCCEEEEEEEECC
>Mature Secondary Structure 
TMSQDSRSTPGSTVDPAEIAKFSKLSETWWDPKGKMAPLHKINPLRLTYIRDAACRKFE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHH
RNAKSLNCLSGLRMLDIGCGAGLLCEPFTRLGAQVVGVDPSASNIAAAKLHAEKGHMSID
HCCHHHHHHHCCEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCEEEE
YRCTTIEEMDPRERFDIVLAMEVVEHVTDVGAFLGRCAAVLKPGGLMVVSTLNRNWKSFA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LAIVGAEYVLRWLPRGTHEWSKFVTPDELTKYLLDNRLVITEQSGVVYSPFADRWSLSSD
HHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCC
MDVNYMVVAEQMV
CCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA