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The map label for this gene is obgE [H]

Identifier: 146337577

GI number: 146337577

Start: 443284

End: 444354

Strand: Reverse

Name: obgE [H]

Synonym: BRADO0432

Alternate gene names: 146337577

Gene position: 444354-443284 (Counterclockwise)

Preceding gene: 146337579

Following gene: 146337576

Centisome position: 5.96

GC content: 66.29

Gene sequence:

>1071_bases
ATGAAATTCCTCGATGAAGCCAAGGTCTATGTGCGCTCGGGCGACGGCGGCAACGGTTGCGTTGCGTTCCGGCGCGAGAA
GTTCATCGAGTTCGGCGGCCCGAACGGCGGCAATGGCGGCCGCGGCGGCGACGTCGTGATCGAGGCCGTCGACGGCCTCA
ACACCCTGATCGACTACCGTTACCAGCAGCATTTCAAGGCCCAAAAGGGCGAGAACGGCATGGGCAAGGACCGCCACGGC
GCCGGTGGCAAGTCGATCGTGCTCAAGGTTCCCGTCGGCACCCAGATCTTCGACGAGGATCGCGAGACACTGATCCACGA
CTTCACCGCCGTCGGCGAGCGATTCGTGCTGGCCGAGGGCGGCAATGGCGGCTTCGGCAACGCGCATTTCAAGTCGCCGA
CCAACCGTGCGCCGCGGCATGCCAATCCCGGCCAGCCCGGCGAGGAGCGCTGGATCTGGCTGCGCATGAAGCTGATCGCC
GATGCCGGCCTCGTCGGACTGCCCAATGCCGGCAAATCGACGTTCTTGTCCAAGGTGTCGGCGGCCAAGCCGAAGATCGC
CGACTATCCGTTCACCACCCTGCATCCGCAGCTCGGCGTGGTGAATGCCGACGGCCGCGAATTTGTGCTCGCCGACATTC
CCGGCCTGATCGAGGGCGCGCATGAGGGCGCCGGTCTCGGCGACCGCTTCCTCGGCCATGTCGAGCGCTGCCGCGTGCTG
CTGCACCTGGTCGATGCCACCTGCGAGCATGCCGGCAAGGCCTACAAGACGGTGCGGCACGAGCTCGAGGCCTATGGCGG
CGACCTGACCGACAAGATCGAGATCGTCGCGCTGAACAAGATCGACGCGGTTGATCCGGACGAGCTGAAGAAGCAGCGGG
ACCGGCTGAAGCGCGCCGCCAAGAAGACGCCGATACTGATCTCCGGTGCGACCGGCGAAGGCGTCAAGGAGGCGCTGCGC
AAGCTCGCCGACGTGGTCGGCGAACAGCCGGTGTCGAGCAAGGCGAAGAACGCAGTCGAGAGCGCCGCAACCGAGGAGCC
GTGGGCGGCTCCGGTCCCGCCGCAAGGCTGA

Upstream 100 bases:

>100_bases
TGCGCAGCGCCGCTTTACCGCTCGAAATTACGGCTTCCGGCCGAATTAACCGCATTCCGCGGTTGCTGTTGGGGGCTGCC
TCGCCTACGTAGGGCGCATC

Downstream 100 bases:

>100_bases
CGCTCAAGCCAGCCTTGCCTCGCACGCGTCCGCTTGCGAAAGTCGCCACTTCATCAACACGCCCCTCGTTTCGTGATGCT
GCGCCACGCAGCTCCCTCTC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYRYQQHFKAQKGENGMGKDRHG
AGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEGGNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIA
DAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVL
LHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAAKKTPILISGATGEGVKEALR
KLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG

Sequences:

>Translated_356_residues
MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYRYQQHFKAQKGENGMGKDRHG
AGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEGGNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIA
DAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVL
LHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAAKKTPILISGATGEGVKEALR
KLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG
>Mature_356_residues
MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYRYQQHFKAQKGENGMGKDRHG
AGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEGGNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIA
DAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVL
LHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAAKKTPILISGATGEGVKEALR
KLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=325, Percent_Identity=40.3076923076923, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI111955139, Length=385, Percent_Identity=34.8051948051948, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI111955063, Length=219, Percent_Identity=36.0730593607306, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4758796, Length=113, Percent_Identity=37.1681415929204, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4557537, Length=88, Percent_Identity=39.7727272727273, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI58761500, Length=147, Percent_Identity=31.2925170068027, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=354, Percent_Identity=49.7175141242938, Blast_Score=294, Evalue=5e-81,
Organism=Escherichia coli, GI1790615, Length=171, Percent_Identity=29.8245614035088, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787454, Length=102, Percent_Identity=37.2549019607843, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=281, Percent_Identity=43.4163701067616, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=309, Percent_Identity=31.0679611650485, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17555344, Length=107, Percent_Identity=36.4485981308411, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=102, Percent_Identity=35.2941176470588, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=113, Percent_Identity=36.283185840708, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=158, Percent_Identity=41.7721518987342, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=137, Percent_Identity=32.8467153284672, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=103, Percent_Identity=36.8932038834951, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129375, Length=339, Percent_Identity=37.7581120943953, Blast_Score=171, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=39.041095890411, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17981711, Length=113, Percent_Identity=36.283185840708, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356473, Length=113, Percent_Identity=34.5132743362832, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38195; Mature: 38195

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYR
CCCCCCCEEEEEECCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
YQQHFKAQKGENGMGKDRHGAGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
GNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIADAGLVGLPNAGKSTFLSKVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCCEECCCCCHHHHHHHHH
AAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVL
HCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
KKTPILISGATGEGVKEALRKLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG
HCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLDEAKVYVRSGDGGNGCVAFRREKFIEFGGPNGGNGGRGGDVVIEAVDGLNTLIDYR
CCCCCCCEEEEEECCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
YQQHFKAQKGENGMGKDRHGAGGKSIVLKVPVGTQIFDEDRETLIHDFTAVGERFVLAEG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
GNGGFGNAHFKSPTNRAPRHANPGQPGEERWIWLRMKLIADAGLVGLPNAGKSTFLSKVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCCEECCCCCHHHHHHHHH
AAKPKIADYPFTTLHPQLGVVNADGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVL
HCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDATCEHAGKAYKTVRHELEAYGGDLTDKIEIVALNKIDAVDPDELKKQRDRLKRAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
KKTPILISGATGEGVKEALRKLADVVGEQPVSSKAKNAVESAATEEPWAAPVPPQG
HCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA