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The map label for this gene is phhB

Identifier: 146337416

GI number: 146337416

Start: 270442

End: 270744

Strand: Reverse

Name: phhB

Synonym: BRADO0254

Alternate gene names: NA

Gene position: 270744-270442 (Counterclockwise)

Preceding gene: 146337419

Following gene: 146337415

Centisome position: 3.63

GC content: 67.99

Gene sequence:

>303_bases
ATGGTGGAGCGACTGTCGGCCGAGGCGCGCGCGAGCGCCCTGCGGGATCTTTCGGGCTGGGCCGAGCTCGACGGCCGCGA
GGCGATCAGCCGGACGTTCACCTTCCGGGATTTCAACGAAGCCTTCGGCTTCATGACACGGGTCGCGCTCATCGCCGAGA
AGCGCGATCATCATCCGGAGTGGCGGAACGTCTACCGCACCGTCGAGGTGGTGCTCGCCACCCACGATGCCGGCGGCGTG
ACCATGCTCGACATCGAGCTGGCGCGCGCGATGGACGCGATTGCGGCTGCGATCAGCGGCTGA

Upstream 100 bases:

>100_bases
CTGGCGGCCAGCGCGTGGTCGGGGGCCGTGAACTGACCGGTAAGTTTCGGCTCGTCCGGTCGGCCGGCGAGACGACGGTG
GATGGAATCGGAGGATTGCA

Downstream 100 bases:

>100_bases
CATCGTCCAGCTGCGTCCTGTCCTGCACGGCCCTGCGACGCTCGTGGCGCCTTGCGGCAGAGGATGGCCGCCCCACATGA
ACCGCGGGATGACCGCGCTG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MVERLSAEARASALRDLSGWAELDGREAISRTFTFRDFNEAFGFMTRVALIAEKRDHHPEWRNVYRTVEVVLATHDAGGV
TMLDIELARAMDAIAAAISG

Sequences:

>Translated_100_residues
MVERLSAEARASALRDLSGWAELDGREAISRTFTFRDFNEAFGFMTRVALIAEKRDHHPEWRNVYRTVEVVLATHDAGGV
TMLDIELARAMDAIAAAISG
>Mature_100_residues
MVERLSAEARASALRDLSGWAELDGREAISRTFTFRDFNEAFGFMTRVALIAEKRDHHPEWRNVYRTVEVVLATHDAGGV
TMLDIELARAMDAIAAAISG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=98, Percent_Identity=54.0816326530612, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI134133240, Length=99, Percent_Identity=50.5050505050505, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI115533705, Length=92, Percent_Identity=52.1739130434783, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45549100, Length=97, Percent_Identity=49.4845360824742, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_BRASO (A4YJY8)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001202464.1
- ProteinModelPortal:   A4YJY8
- SMR:   A4YJY8
- STRING:   A4YJY8
- GeneID:   5116664
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO0254
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   SEERKTR
- ProtClustDB:   PRK00823
- BioCyc:   BSP376:BRADO0254-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11123; Mature: 11123

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERLSAEARASALRDLSGWAELDGREAISRTFTFRDFNEAFGFMTRVALIAEKRDHHPE
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHH
WRNVYRTVEVVLATHDAGGVTMLDIELARAMDAIAAAISG
HHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVERLSAEARASALRDLSGWAELDGREAISRTFTFRDFNEAFGFMTRVALIAEKRDHHPE
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHH
WRNVYRTVEVVLATHDAGGVTMLDIELARAMDAIAAAISG
HHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA