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The map label for this gene is holA

Identifier: 146337358

GI number: 146337358

Start: 203873

End: 204901

Strand: Direct

Name: holA

Synonym: BRADO0191

Alternate gene names: NA

Gene position: 203873-204901 (Clockwise)

Preceding gene: 146337357

Following gene: 146337366

Centisome position: 2.73

GC content: 68.8

Gene sequence:

>1029_bases
GTGGTCGCGCTGCGCGGACGAGACATCGACGCCTTTCTCGCCAAGCCGGACGCGGCCCGTCCGCTGATCCTGCTGTATGG
TCCGGACGCGGGCCTGGTCCGCGAACGAGCCGAGGCGCTAATCGCCTCCGCCGTCGACAATCCCGACGATCCGTTTTCCG
TCGTGCGCCTCGATGGCGACGAGCTCGCTGCCGAGCCGTCGCGCCTGGTCGACGAGGCGATGACCGTGCCGCTGTTCGGC
GGCCGCCGCGCCATCCGTGTCCGCGCCGGATCGCGTATCTTCGCCAGTGGCGTCGAGACACTGAGCCAGATGAATGTGCG
CGACTGCCGGATCGTCATCGAGGCCGGCGACATCCGGCCCGATTCGCCGCTGCGCAAGATCTGCGAAAAGGCCGCGACCG
CCGTGGCGATTGGCTGCTATCCCGACACGGAGCGCGATCTCGCCAGGCTGATCGACGACGAACTGCGCACCGCTAATCTG
CGCATGGCGCCAGATGCGCGGTCATATCTGATGGCGCTGCTCGGCGGCGACCGCCAGGCGTCGCGCAACGAGATCCGCAA
GCTGACGCTGTTCGCGCATGGCGAAGGCGAGGTGACGCTCGACCATGTGATGGCGGTGGTCGCCGATGCCTCCGAGATGA
AGCTCGACCCGATCGTCGACGGCGCCTTCGGCGGCAAGCCCGACGTGGTCGAGACCGAGTTCGGCAAGGCGATGATCGCC
GGCACCTATCCCGGTGTGATCATCTCGGCGGCGCAGCGTCATGCGGCGTGGCTGCACAAATCGGCGCTCGCCGTCGCTTC
GGGCGCGCCGGTCTCCTCCATCCTCGAGGGTGGGTTTCCGCGGCTGCACTTCTCGCGCAAGCCGAGCGCCGAAGTCGCGC
TGCGCAACTTCTCCCCTGCCCGGCTGCTGCCGATCATCGACCAGCTGGCCACGGCCGCGCTCGACATGCGCAAGCAGCCG
GGACTGGCGGCCGCGATCGCGCAGCGGACGTTGCTGTCGATCGCCGTGGCGGCACGGCGGAAGGGATGA

Upstream 100 bases:

>100_bases
CGATGCCGAGGACCGCGCCTCGGAGGAGGTCGCGGAGAAGATCAAGACGCGGCTCGCGGCCTATTTCACCGCGGGCACCT
GACGCACGGCTGACACCGCC

Downstream 100 bases:

>100_bases
TGATTCAGAATGGGGCTCAGGCGGCAGCGGTGTCGAAGACATCGGCTCGTTGACGCGCGACGTCGAATACGTAGTCCCAG
TGAACCCGAGACGCCTCCCC

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVALRGRDIDAFLAKPDAARPLILLYGPDAGLVRERAEALIASAVDNPDDPFSVVRLDGDELAAEPSRLVDEAMTVPLFG
GRRAIRVRAGSRIFASGVETLSQMNVRDCRIVIEAGDIRPDSPLRKICEKAATAVAIGCYPDTERDLARLIDDELRTANL
RMAPDARSYLMALLGGDRQASRNEIRKLTLFAHGEGEVTLDHVMAVVADASEMKLDPIVDGAFGGKPDVVETEFGKAMIA
GTYPGVIISAAQRHAAWLHKSALAVASGAPVSSILEGGFPRLHFSRKPSAEVALRNFSPARLLPIIDQLATAALDMRKQP
GLAAAIAQRTLLSIAVAARRKG

Sequences:

>Translated_342_residues
MVALRGRDIDAFLAKPDAARPLILLYGPDAGLVRERAEALIASAVDNPDDPFSVVRLDGDELAAEPSRLVDEAMTVPLFG
GRRAIRVRAGSRIFASGVETLSQMNVRDCRIVIEAGDIRPDSPLRKICEKAATAVAIGCYPDTERDLARLIDDELRTANL
RMAPDARSYLMALLGGDRQASRNEIRKLTLFAHGEGEVTLDHVMAVVADASEMKLDPIVDGAFGGKPDVVETEFGKAMIA
GTYPGVIISAAQRHAAWLHKSALAVASGAPVSSILEGGFPRLHFSRKPSAEVALRNFSPARLLPIIDQLATAALDMRKQP
GLAAAIAQRTLLSIAVAARRKG
>Mature_342_residues
MVALRGRDIDAFLAKPDAARPLILLYGPDAGLVRERAEALIASAVDNPDDPFSVVRLDGDELAAEPSRLVDEAMTVPLFG
GRRAIRVRAGSRIFASGVETLSQMNVRDCRIVIEAGDIRPDSPLRKICEKAATAVAIGCYPDTERDLARLIDDELRTANL
RMAPDARSYLMALLGGDRQASRNEIRKLTLFAHGEGEVTLDHVMAVVADASEMKLDPIVDGAFGGKPDVVETEFGKAMIA
GTYPGVIISAAQRHAAWLHKSALAVASGAPVSSILEGGFPRLHFSRKPSAEVALRNFSPARLLPIIDQLATAALDMRKQP
GLAAAIAQRTLLSIAVAARRKG

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921 [H]

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 36599; Mature: 36599

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALRGRDIDAFLAKPDAARPLILLYGPDAGLVRERAEALIASAVDNPDDPFSVVRLDGD
CEEECCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
ELAAEPSRLVDEAMTVPLFGGRRAIRVRAGSRIFASGVETLSQMNVRDCRIVIEAGDIRP
HHHCCHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
DSPLRKICEKAATAVAIGCYPDTERDLARLIDDELRTANLRMAPDARSYLMALLGGDRQA
CCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCC
SRNEIRKLTLFAHGEGEVTLDHVMAVVADASEMKLDPIVDGAFGGKPDVVETEFGKAMIA
CHHHHEEEEEEECCCCCEEHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCEECCCCCEEEE
GTYPGVIISAAQRHAAWLHKSALAVASGAPVSSILEGGFPRLHFSRKPSAEVALRNFSPA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCCHHEEECCCCCH
RLLPIIDQLATAALDMRKQPGLAAAIAQRTLLSIAVAARRKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVALRGRDIDAFLAKPDAARPLILLYGPDAGLVRERAEALIASAVDNPDDPFSVVRLDGD
CEEECCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCH
ELAAEPSRLVDEAMTVPLFGGRRAIRVRAGSRIFASGVETLSQMNVRDCRIVIEAGDIRP
HHHCCHHHHHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
DSPLRKICEKAATAVAIGCYPDTERDLARLIDDELRTANLRMAPDARSYLMALLGGDRQA
CCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCC
SRNEIRKLTLFAHGEGEVTLDHVMAVVADASEMKLDPIVDGAFGGKPDVVETEFGKAMIA
CHHHHEEEEEEECCCCCEEHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCEECCCCCEEEE
GTYPGVIISAAQRHAAWLHKSALAVASGAPVSSILEGGFPRLHFSRKPSAEVALRNFSPA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCCHHEEECCCCCH
RLLPIIDQLATAALDMRKQPGLAAAIAQRTLLSIAVAARRKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]