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The map label for this gene is gpmA [H]

Identifier: 146337326

GI number: 146337326

Start: 170819

End: 171442

Strand: Reverse

Name: gpmA [H]

Synonym: BRADO0157

Alternate gene names: 146337326

Gene position: 171442-170819 (Counterclockwise)

Preceding gene: 146337327

Following gene: 146337325

Centisome position: 2.3

GC content: 66.35

Gene sequence:

>624_bases
ATGAGCGAACGTCTCCTGGTGCTGGTGCGCCACGGCCAGAGCGAGTGGAACCTGAAGAACCTGTTCACCGGCTGGAAGGA
TCCTGACCTCACCGCGCAGGGCGTCAGCGAAGCCAAGGACGCCGGCCGCAAGCTGAAGGCGCATGGCCTGTCCTTCGATG
TCGCCTTCACCTCCGAGCTGACCCGCGCCCAGCACACCCTGAAGCTGATCCTCGACGAGCTCGGCCAGCCCGGCCTGCCG
ACGTCGAAGAACCTCGCGCTCAACGAGCGCGACTATGGCGATCTCTCCGGCCTCAATAAGGACGACGCCCGCGCCAAATG
GGGCGAGGAGCAGGTCCACGTCTGGCGCCGCTCCTACGACGTCCCCCCGCCCGGCGGCGAAAGCCTCAAGGACACCCTCG
CCCGCGCGCTGCCCTACTACGTCCAGGAAATCCTCCCCGGCGTCCTCAACGGCCAGCGCACTTTGGTCGCCGCCCACGGC
AACTCGCTCCGCGCCTTGATCATGGTGCTGGAGAAGCTGACCCCGGAAGGCATTTTGAAGCGCGAGCTCGCCACCGGCGT
TCCGATCATCTACCGCCTGAAGGCGGATTCGACGGTGGAGTCGAAGCTGGATCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
GGCGCTGTGGGCCCATGGCAAGCCGCCGGGCTACTACACGATGGACGACGTGCTCGGCCTCAAGGACCTGTTCTAATCAA
ACCAAGTGGATCTGTTAGCA

Downstream 100 bases:

>100_bases
GCGCGGCAACGTCAACGTTGCGATCGCGCTTCGGTCACGTTCGACGTTGCTCCTCTGAGTTGGATACCCGCCGTTCCCCA
AGCGCCGCTGCACTCCCTCT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTAQGVSEAKDAGRKLKAHGLSFDVAFTSELTRAQHTLKLILDELGQPGLP
TSKNLALNERDYGDLSGLNKDDARAKWGEEQVHVWRRSYDVPPPGGESLKDTLARALPYYVQEILPGVLNGQRTLVAAHG
NSLRALIMVLEKLTPEGILKRELATGVPIIYRLKADSTVESKLDLAG

Sequences:

>Translated_207_residues
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTAQGVSEAKDAGRKLKAHGLSFDVAFTSELTRAQHTLKLILDELGQPGLP
TSKNLALNERDYGDLSGLNKDDARAKWGEEQVHVWRRSYDVPPPGGESLKDTLARALPYYVQEILPGVLNGQRTLVAAHG
NSLRALIMVLEKLTPEGILKRELATGVPIIYRLKADSTVESKLDLAG
>Mature_206_residues
SERLLVLVRHGQSEWNLKNLFTGWKDPDLTAQGVSEAKDAGRKLKAHGLSFDVAFTSELTRAQHTLKLILDELGQPGLPT
SKNLALNERDYGDLSGLNKDDARAKWGEEQVHVWRRSYDVPPPGGESLKDTLARALPYYVQEILPGVLNGQRTLVAAHGN
SLRALIMVLEKLTPEGILKRELATGVPIIYRLKADSTVESKLDLAG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=220, Percent_Identity=46.8181818181818, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI50593010, Length=223, Percent_Identity=43.4977578475336, Blast_Score=190, Evalue=6e-49,
Organism=Homo sapiens, GI71274132, Length=220, Percent_Identity=44.0909090909091, Blast_Score=177, Evalue=7e-45,
Organism=Homo sapiens, GI4502445, Length=222, Percent_Identity=42.7927927927928, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI40353764, Length=222, Percent_Identity=42.7927927927928, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=46.6666666666667, Blast_Score=134, Evalue=4e-32,
Organism=Escherichia coli, GI1786970, Length=218, Percent_Identity=47.2477064220183, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1786857, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322697, Length=213, Percent_Identity=41.3145539906103, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324516, Length=265, Percent_Identity=25.6603773584906, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320183, Length=269, Percent_Identity=23.7918215613383, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324857, Length=163, Percent_Identity=28.8343558282209, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24646216, Length=216, Percent_Identity=43.5185185185185, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI85725270, Length=216, Percent_Identity=45.3703703703704, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI85725272, Length=216, Percent_Identity=45.3703703703704, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24650981, Length=216, Percent_Identity=45.3703703703704, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28571815, Length=216, Percent_Identity=35.1851851851852, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28571817, Length=216, Percent_Identity=35.1851851851852, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24648979, Length=216, Percent_Identity=35.1851851851852, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22858; Mature: 22727

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLLVLVRHGQSEWNLKNLFTGWKDPDLTAQGVSEAKDAGRKLKAHGLSFDVAFTSEL
CCCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
TRAQHTLKLILDELGQPGLPTSKNLALNERDYGDLSGLNKDDARAKWGEEQVHVWRRSYD
HHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCC
VPPPGGESLKDTLARALPYYVQEILPGVLNGQRTLVAAHGNSLRALIMVLEKLTPEGILK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCHHHHHH
RELATGVPIIYRLKADSTVESKLDLAG
HHHHCCCCEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
SERLLVLVRHGQSEWNLKNLFTGWKDPDLTAQGVSEAKDAGRKLKAHGLSFDVAFTSEL
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
TRAQHTLKLILDELGQPGLPTSKNLALNERDYGDLSGLNKDDARAKWGEEQVHVWRRSYD
HHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCC
VPPPGGESLKDTLARALPYYVQEILPGVLNGQRTLVAAHGNSLRALIMVLEKLTPEGILK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCHHHHHH
RELATGVPIIYRLKADSTVESKLDLAG
HHHHCCCCEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA