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The map label for this gene is rnd [H]

Identifier: 146337290

GI number: 146337290

Start: 131761

End: 132375

Strand: Reverse

Name: rnd [H]

Synonym: BRADO0117

Alternate gene names: 146337290

Gene position: 132375-131761 (Counterclockwise)

Preceding gene: 146337294

Following gene: 146337289

Centisome position: 1.78

GC content: 64.72

Gene sequence:

>615_bases
ATGACCGTTCGCCTGCATCGGGGCGACCTGCCCGATCTCTCCCGCTACACCTCGTCGGTCGCGATCGACACCGAGACGAT
GGGGCTCAATCCGCACCGCGACCGGCTGTGCGTGGTGCAGCTGTCGCCCGGCGACGGCTCGGCCGATGTGGTGCAGATCC
CCAAGGGGCACACCGACGCGCCGAATTTGAAGACGCTACTCGGCAATACCGCCATCACCAAGATCTTCCACTTCGCGCGC
TTCGACGTCGCGACGCTGTTTCATACTTTCGGGGTGATGCCGCAACCGGTCTATTGCACCAAGATCGCGTCGCGGCTGGC
ACGCACCTATACCGACCGCCACGGACTGAAGGATCTCGTCCGCGAGCTGCTCAACATCGATCTGTCCAAGCAGCAGCAGT
CGAGCGACTGGGGCGCCGATAGCCTGAGTGAGCCGCAGCTGGCCTATGCGGCCTCCGACGTTCTGCATCTGCATGCGCTC
CGCGAGAAGCTCGACGTGATGCTGGCGCGCGAAGGCCGGCTGGCGCTGGCGCAGGCCTGCTTCGCCTTCCTGCCGCATCG
CGCGACGCTCGATTTGGGCGGATTCGAGGCCGACGACATCTTTGCGCATTCGTGA

Upstream 100 bases:

>100_bases
GCCGGGCTAAAGCCGGTTCCTGGCCGCTTGCTGGCCGTTTCCTGCGACGTCGCCCCGGCCCGTCGCGTTCGACATCGCTT
CGACCGAGGTTTTGACCGCC

Downstream 100 bases:

>100_bases
GGGTGCGACGGCCGGGCGCGTTCAGGATCATTAATCTCTCTTAATGATTGAACGGCTTCTGCGTCGCGATTTCGCGGCAG
TTCCGGGCTGCAATGGCCGG

Product: putative 3'-5' exonuclease family protein

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTVRLHRGDLPDLSRYTSSVAIDTETMGLNPHRDRLCVVQLSPGDGSADVVQIPKGHTDAPNLKTLLGNTAITKIFHFAR
FDVATLFHTFGVMPQPVYCTKIASRLARTYTDRHGLKDLVRELLNIDLSKQQQSSDWGADSLSEPQLAYAASDVLHLHAL
REKLDVMLAREGRLALAQACFAFLPHRATLDLGGFEADDIFAHS

Sequences:

>Translated_204_residues
MTVRLHRGDLPDLSRYTSSVAIDTETMGLNPHRDRLCVVQLSPGDGSADVVQIPKGHTDAPNLKTLLGNTAITKIFHFAR
FDVATLFHTFGVMPQPVYCTKIASRLARTYTDRHGLKDLVRELLNIDLSKQQQSSDWGADSLSEPQLAYAASDVLHLHAL
REKLDVMLAREGRLALAQACFAFLPHRATLDLGGFEADDIFAHS
>Mature_203_residues
TVRLHRGDLPDLSRYTSSVAIDTETMGLNPHRDRLCVVQLSPGDGSADVVQIPKGHTDAPNLKTLLGNTAITKIFHFARF
DVATLFHTFGVMPQPVYCTKIASRLARTYTDRHGLKDLVRELLNIDLSKQQQSSDWGADSLSEPQLAYAASDVLHLHALR
EKLDVMLAREGRLALAQACFAFLPHRATLDLGGFEADDIFAHS

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=164, Percent_Identity=32.9268292682927, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 22548; Mature: 22417

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRLHRGDLPDLSRYTSSVAIDTETMGLNPHRDRLCVVQLSPGDGSADVVQIPKGHTDA
CEEEECCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCC
PNLKTLLGNTAITKIFHFARFDVATLFHTFGVMPQPVYCTKIASRLARTYTDRHGLKDLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHH
RELLNIDLSKQQQSSDWGADSLSEPQLAYAASDVLHLHALREKLDVMLAREGRLALAQAC
HHHHCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FAFLPHRATLDLGGFEADDIFAHS
HHHCCCCCEEECCCCCCCHHCCCC
>Mature Secondary Structure 
TVRLHRGDLPDLSRYTSSVAIDTETMGLNPHRDRLCVVQLSPGDGSADVVQIPKGHTDA
EEEECCCCCCHHHHHHHHEEEECCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCCCCC
PNLKTLLGNTAITKIFHFARFDVATLFHTFGVMPQPVYCTKIASRLARTYTDRHGLKDLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHH
RELLNIDLSKQQQSSDWGADSLSEPQLAYAASDVLHLHALREKLDVMLAREGRLALAQAC
HHHHCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FAFLPHRATLDLGGFEADDIFAHS
HHHCCCCCEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]