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The map label for this gene is aroA [H]

Identifier: 146337271

GI number: 146337271

Start: 114433

End: 115770

Strand: Reverse

Name: aroA [H]

Synonym: BRADO0098

Alternate gene names: 146337271

Gene position: 115770-114433 (Counterclockwise)

Preceding gene: 146337274

Following gene: 146337270

Centisome position: 1.55

GC content: 69.28

Gene sequence:

>1338_bases
GTGAGCACGTCAGCTGCCCCCACTCCGCTCGAATCCCGCGCCTCCGGGCCGCTTTCGGGCACGATTCGCGTGCCCGGCGA
CAAGTCGATCTCGCACCGGGCGCTGATCCTGGGCGCGCTGTCGGTGGGCGGGACGCGGATTTCCGGTCTGCTGGAGGGCG
AGGACGTCCTCAACACCGCCAAGTCGATGCGCACGCTCGGGGCCAAGGTCGAACGCACCGGCGAATTCGCCTGGACCGTG
AACGGCGTCGGCGTCGGCGGCTTTGCCCAGCCCGCCGCGACTCTCGATTTCGGCAACTCCGGCACCGGCTGCCGGCTGGT
GATGGGCGCCGTCGCCGGCTGCCCGATCTCGGCGGTGTTCGACGGCGATGCCTCGCTGCGCAGCCGGCCGATGCGCCGCA
TCCTCGATCCCTTGGCATTGATGGGCGCCAAGGTCACGGCCAGCGCCGAGGGCGGAAAGCTTCCGTTAACCCTGCAGGGC
GCCAGCAACCCGGTGCCGATCGAGTATCGCACGCCGGTCGCCTCGGCGCAGATCAAGTCGGCGGTCCTGCTGGCCGGCCT
CGCGGCGCCCGGCGTCACGACCGTGATCGAGCAGGAGGCGAGTCGCGACCACACCGAGCTGATGCTCAAGCATTTCGGCG
CCGAGATCGTCACCACGCCGGAAGGCAGCCACGGCCGACGCATTGCGCTAACGGGCCAGCCCGAGCTTCGCGGCGCGCCG
GTGATCGTGCCGGCCGACCCGTCCTCGGCCGCCTTCCCGCTGGTTGCCGCCCTGATCGTCGATGGTTCCGACCTGGTCTT
GTCCGACGTCATGACCAACCCGTTGCGAACCGGCCTGTTCACGACCCTGCGCGAGATGGGCGCCTCGATCGAGGAGGACG
ACGTCCGTGGCGATGCCGGCGAGCCGATGGCCCGCCTGCGGGTCCGCGCCTCGAAGCTGAAGGGCGTCGAGGTGCCGCCG
GAGCGGGCGCCGTCGATGATCGACGAATATCTCGTCCTCGCCGTCGCCGCCGCCTATGCCGAGGGCACCACGATCATGCG
TGGCCTGCACGAGCTGCGCGTCAAGGAATCCGACCGCCTGGAAGCCACTGCAGCGATGCTGCGCGTCAATGGCGTCAAGG
TCGAGATCACCGGCGATGACCTCATCGTCGAGGGCCGCGGCCACGTCCCGGGTGGCGGCCTCGTCGCCACCCACATGGAC
CACCGCATCGCGATGTCCGCGCTGGTGATGGGTTTGGCCTCCGACAAACCGGTGACTGTCGATGACACCGCCTTCATCGC
CACCAGCTTCCCGGATTTCATCCCGCTGATGCGCAAGGCGGGAGCGGATTTCGCATGA

Upstream 100 bases:

>100_bases
TGCCGCGCCGCTGTCAATAGCGCTTTCAACCGGATATCACGGCCGTGACGGCCGCCGGGCGCTGTGATACCTGCCGGCCC
GAAAACCCGAGGATCCCACC

Downstream 100 bases:

>100_bases
TCATCGCCATCGACGGCCCGGCTGCCTCGGGCAAGGGCACCATGGCCAAGCGCCTCGCGGCGCATTATGGCCTCAGGCAC
CTGGATACGGGTGTGATCTA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSTSAAPTPLESRASGPLSGTIRVPGDKSISHRALILGALSVGGTRISGLLEGEDVLNTAKSMRTLGAKVERTGEFAWTV
NGVGVGGFAQPAATLDFGNSGTGCRLVMGAVAGCPISAVFDGDASLRSRPMRRILDPLALMGAKVTASAEGGKLPLTLQG
ASNPVPIEYRTPVASAQIKSAVLLAGLAAPGVTTVIEQEASRDHTELMLKHFGAEIVTTPEGSHGRRIALTGQPELRGAP
VIVPADPSSAAFPLVAALIVDGSDLVLSDVMTNPLRTGLFTTLREMGASIEEDDVRGDAGEPMARLRVRASKLKGVEVPP
ERAPSMIDEYLVLAVAAAYAEGTTIMRGLHELRVKESDRLEATAAMLRVNGVKVEITGDDLIVEGRGHVPGGGLVATHMD
HRIAMSALVMGLASDKPVTVDDTAFIATSFPDFIPLMRKAGADFA

Sequences:

>Translated_445_residues
MSTSAAPTPLESRASGPLSGTIRVPGDKSISHRALILGALSVGGTRISGLLEGEDVLNTAKSMRTLGAKVERTGEFAWTV
NGVGVGGFAQPAATLDFGNSGTGCRLVMGAVAGCPISAVFDGDASLRSRPMRRILDPLALMGAKVTASAEGGKLPLTLQG
ASNPVPIEYRTPVASAQIKSAVLLAGLAAPGVTTVIEQEASRDHTELMLKHFGAEIVTTPEGSHGRRIALTGQPELRGAP
VIVPADPSSAAFPLVAALIVDGSDLVLSDVMTNPLRTGLFTTLREMGASIEEDDVRGDAGEPMARLRVRASKLKGVEVPP
ERAPSMIDEYLVLAVAAAYAEGTTIMRGLHELRVKESDRLEATAAMLRVNGVKVEITGDDLIVEGRGHVPGGGLVATHMD
HRIAMSALVMGLASDKPVTVDDTAFIATSFPDFIPLMRKAGADFA
>Mature_444_residues
STSAAPTPLESRASGPLSGTIRVPGDKSISHRALILGALSVGGTRISGLLEGEDVLNTAKSMRTLGAKVERTGEFAWTVN
GVGVGGFAQPAATLDFGNSGTGCRLVMGAVAGCPISAVFDGDASLRSRPMRRILDPLALMGAKVTASAEGGKLPLTLQGA
SNPVPIEYRTPVASAQIKSAVLLAGLAAPGVTTVIEQEASRDHTELMLKHFGAEIVTTPEGSHGRRIALTGQPELRGAPV
IVPADPSSAAFPLVAALIVDGSDLVLSDVMTNPLRTGLFTTLREMGASIEEDDVRGDAGEPMARLRVRASKLKGVEVPPE
RAPSMIDEYLVLAVAAAYAEGTTIMRGLHELRVKESDRLEATAAMLRVNGVKVEITGDDLIVEGRGHVPGGGLVATHMDH
RIAMSALVMGLASDKPVTVDDTAFIATSFPDFIPLMRKAGADFA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=428, Percent_Identity=31.7757009345794, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320332, Length=431, Percent_Identity=27.8422273781903, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46190; Mature: 46059

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSAAPTPLESRASGPLSGTIRVPGDKSISHRALILGALSVGGTRISGLLEGEDVLNTA
CCCCCCCCCCHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEEEECCHHHHHHH
KSMRTLGAKVERTGEFAWTVNGVGVGGFAQPAATLDFGNSGTGCRLVMGAVAGCPISAVF
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
DGDASLRSRPMRRILDPLALMGAKVTASAEGGKLPLTLQGASNPVPIEYRTPVASAQIKS
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCEEEECCCHHHHHHH
AVLLAGLAAPGVTTVIEQEASRDHTELMLKHFGAEIVTTPEGSHGRRIALTGQPELRGAP
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCC
VIVPADPSSAAFPLVAALIVDGSDLVLSDVMTNPLRTGLFTTLREMGASIEEDDVRGDAG
EEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPMARLRVRASKLKGVEVPPERAPSMIDEYLVLAVAAAYAEGTTIMRGLHELRVKESDRL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHH
EATAAMLRVNGVKVEITGDDLIVEGRGHVPGGGLVATHMDHRIAMSALVMGLASDKPVTV
HHHHHHEEECCEEEEECCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEE
DDTAFIATSFPDFIPLMRKAGADFA
CCCEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STSAAPTPLESRASGPLSGTIRVPGDKSISHRALILGALSVGGTRISGLLEGEDVLNTA
CCCCCCCCCHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCEEEEEEECCHHHHHHH
KSMRTLGAKVERTGEFAWTVNGVGVGGFAQPAATLDFGNSGTGCRLVMGAVAGCPISAVF
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEE
DGDASLRSRPMRRILDPLALMGAKVTASAEGGKLPLTLQGASNPVPIEYRTPVASAQIKS
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCEEEECCCHHHHHHH
AVLLAGLAAPGVTTVIEQEASRDHTELMLKHFGAEIVTTPEGSHGRRIALTGQPELRGAP
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCC
VIVPADPSSAAFPLVAALIVDGSDLVLSDVMTNPLRTGLFTTLREMGASIEEDDVRGDAG
EEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPMARLRVRASKLKGVEVPPERAPSMIDEYLVLAVAAAYAEGTTIMRGLHELRVKESDRL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHH
EATAAMLRVNGVKVEITGDDLIVEGRGHVPGGGLVATHMDHRIAMSALVMGLASDKPVTV
HHHHHHEEECCEEEEECCCEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEE
DDTAFIATSFPDFIPLMRKAGADFA
CCCEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA