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The map label for this gene is bdlA [H]

Identifier: 146337210

GI number: 146337210

Start: 42160

End: 43842

Strand: Reverse

Name: bdlA [H]

Synonym: BRADO0036

Alternate gene names: 146337210

Gene position: 43842-42160 (Counterclockwise)

Preceding gene: 146337223

Following gene: 146337205

Centisome position: 0.59

GC content: 63.81

Gene sequence:

>1683_bases
ATGTCATTCTGGTCAGGCAGCTCGGCATCACGCGATGCATTGGCCCAGGTCGAGGCGATCAATCGCTCCCAGGCCGTGAT
CGAATTCGGCATCGACGGAACGATCATCACCGCCAACAAGAACTTTCTCGATGCGATGGGCTACGCGCTCGACGAGATCA
AGGGCAGGCACCACCGCATGTTCGTCGCGCCGCAGCTGCGTGAGAGTGCCGAGTACAAGGCGTTCTGGTCCGACCTCAAG
CGCGGCAAGTTCCGCTCAGGCGAGTACAAGCGCTTCGGCAAAGGCGAGCGGCCGGTGTGGATCCAGGCGAGCTACAATCC
GGTGCTCGATGGCGGCACGCCGGTGAAGATCATCAAGTTTGCCTCCGACATCACGGCGCAGAAGATGCGCAGCATCGAGG
ATGCCGGCAAGATCGCCGCGATCGGACGTGTGCAGGCGGTGATCGAGTTCAATCTCGATGGAACGATCATCGATGCCAAC
GATCAATTCCTCGGCGCGATGGGCTATACGCTCGGCGAGATCAAGGGCCGGCACCATAGCATGTTCGTGCTCCCGCACGA
GCGCGACAGCGTGGCCTACAAGGAGTTCTGGGCAAGCCTCAACCGCGGTGAACCTCGCTCGGGCGAGTACAAGCGTTGCG
GCAAGGACAACAGGGAGGTCTGGATTCTTGCCTCCTACAATCCGATCCTCGACGACACCGGGCGGCCGTTCAAGGTCGTG
AAATACGCCTCCGACGTCACGCAGCAGAAGCTGATGGCGGCCGACTTCGCCGGCCAGATCGCGGCGATCCGCAAGTCCCA
GGCGGTGATCGAGTTCGACATGAATGGCCATGTGCTCGACGCCAACGACAACTTCCTCAAGACGCTCGGCTACACGCTCG
CCGACATCAAAGGCAGGCATCACCGGATGTTCATGCCGCCGGGTGCAGGCGAGAGCTCTGAGTACCGCGAGTTCTGGGCC
GCGCTGGCGCGCGGCGAGTTTCAGAGCGGCGAGTATGAGCGCGCCGGCAAGGGCGGCCGTCAGGTGTGGATCCAGGCGAC
CTACAATCCGATCAAGGATCTCAACGGCAAGCCGTTCAAGATCGTGAAATTCGCGAGCGACGTGACCGCGCAGGTGATCA
CCCGGATGAAGGGCGACAAGGTGCGCGGCATGATGGAGCATGTCGCGGCCGGTGCCGAGCAGCTCAATTCATCGGTGCAG
CAGATCGCCGACGCCATGGCCAAGTCGAAGGAGACGGCGACCGCCGCCGTGACGCGCGTCGACGATGCGGACCAGCAGGC
CAAGCGGCTGTCGTCGGCGGCCGGCGCGATGAGCAGCATCGTCGAGCTGATCGGCAGCATCACCGGCCAGATCAATCTGC
TCGCGCTCAATGCCACGATCGAATCGGCGCGTGCCGGCGAGGCTGGGCGGGGCTTCGCAGTGGTCGCCGGCGAGGTGAAG
AACCTCGCCAATCAGGCCAAGCAGGCGACGGACCGCATCGGCAGCGAGATCGGCAATCTCAACGGCATCTCATCCGACGT
CGTCGGCGCGCTCGACGCCATCAAGGCCGCGATCCAGAGCGTCGACGCCTATGTCTCGTCGACGGCCCAGGCGGTCGGCG
AGCAGAGCGCGGTCACCAGCGAGATGTCGTCGAACATGCGCCAGGCAGCCGCGGAAGCCGCCACCATCGGCAAGGCGGCC
TGA

Upstream 100 bases:

>100_bases
TCTTTCCGGGCGTGTGGGAGTTGTCCCCTGCATATGTCGCTCCGGCTGATGCTCCCTGCCGAAGCAGGCGTCGCCCCACG
TCCCGAGAAGAGGATCTTCC

Downstream 100 bases:

>100_bases
GGAGAGCAGGGCTATCGCATCCGACGGTCGCTGTCTCGCATTCGCCTTTCACCACGTCGTCATGGCCGGGCTTCTCCCGG
CCATCCACGTCGTCCGGCAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSFWSGSSASRDALAQVEAINRSQAVIEFGIDGTIITANKNFLDAMGYALDEIKGRHHRMFVAPQLRESAEYKAFWSDLK
RGKFRSGEYKRFGKGERPVWIQASYNPVLDGGTPVKIIKFASDITAQKMRSIEDAGKIAAIGRVQAVIEFNLDGTIIDAN
DQFLGAMGYTLGEIKGRHHSMFVLPHERDSVAYKEFWASLNRGEPRSGEYKRCGKDNREVWILASYNPILDDTGRPFKVV
KYASDVTQQKLMAADFAGQIAAIRKSQAVIEFDMNGHVLDANDNFLKTLGYTLADIKGRHHRMFMPPGAGESSEYREFWA
ALARGEFQSGEYERAGKGGRQVWIQATYNPIKDLNGKPFKIVKFASDVTAQVITRMKGDKVRGMMEHVAAGAEQLNSSVQ
QIADAMAKSKETATAAVTRVDDADQQAKRLSSAAGAMSSIVELIGSITGQINLLALNATIESARAGEAGRGFAVVAGEVK
NLANQAKQATDRIGSEIGNLNGISSDVVGALDAIKAAIQSVDAYVSSTAQAVGEQSAVTSEMSSNMRQAAAEAATIGKAA

Sequences:

>Translated_560_residues
MSFWSGSSASRDALAQVEAINRSQAVIEFGIDGTIITANKNFLDAMGYALDEIKGRHHRMFVAPQLRESAEYKAFWSDLK
RGKFRSGEYKRFGKGERPVWIQASYNPVLDGGTPVKIIKFASDITAQKMRSIEDAGKIAAIGRVQAVIEFNLDGTIIDAN
DQFLGAMGYTLGEIKGRHHSMFVLPHERDSVAYKEFWASLNRGEPRSGEYKRCGKDNREVWILASYNPILDDTGRPFKVV
KYASDVTQQKLMAADFAGQIAAIRKSQAVIEFDMNGHVLDANDNFLKTLGYTLADIKGRHHRMFMPPGAGESSEYREFWA
ALARGEFQSGEYERAGKGGRQVWIQATYNPIKDLNGKPFKIVKFASDVTAQVITRMKGDKVRGMMEHVAAGAEQLNSSVQ
QIADAMAKSKETATAAVTRVDDADQQAKRLSSAAGAMSSIVELIGSITGQINLLALNATIESARAGEAGRGFAVVAGEVK
NLANQAKQATDRIGSEIGNLNGISSDVVGALDAIKAAIQSVDAYVSSTAQAVGEQSAVTSEMSSNMRQAAAEAATIGKAA
>Mature_559_residues
SFWSGSSASRDALAQVEAINRSQAVIEFGIDGTIITANKNFLDAMGYALDEIKGRHHRMFVAPQLRESAEYKAFWSDLKR
GKFRSGEYKRFGKGERPVWIQASYNPVLDGGTPVKIIKFASDITAQKMRSIEDAGKIAAIGRVQAVIEFNLDGTIIDAND
QFLGAMGYTLGEIKGRHHSMFVLPHERDSVAYKEFWASLNRGEPRSGEYKRCGKDNREVWILASYNPILDDTGRPFKVVK
YASDVTQQKLMAADFAGQIAAIRKSQAVIEFDMNGHVLDANDNFLKTLGYTLADIKGRHHRMFMPPGAGESSEYREFWAA
LARGEFQSGEYERAGKGGRQVWIQATYNPIKDLNGKPFKIVKFASDVTAQVITRMKGDKVRGMMEHVAAGAEQLNSSVQQ
IADAMAKSKETATAAVTRVDDADQQAKRLSSAAGAMSSIVELIGSITGQINLLALNATIESARAGEAGRGFAVVAGEVKN
LANQAKQATDRIGSEIGNLNGISSDVVGALDAIKAAIQSVDAYVSSTAQAVGEQSAVTSEMSSNMRQAAAEAATIGKAA

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=168, Percent_Identity=36.9047619047619, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787690, Length=204, Percent_Identity=32.843137254902, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788195, Length=167, Percent_Identity=33.5329341317365, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788194, Length=116, Percent_Identity=40.5172413793103, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789453, Length=158, Percent_Identity=33.5443037974684, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 60645; Mature: 60514

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFWSGSSASRDALAQVEAINRSQAVIEFGIDGTIITANKNFLDAMGYALDEIKGRHHRM
CCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCEE
FVAPQLRESAEYKAFWSDLKRGKFRSGEYKRFGKGERPVWIQASYNPVLDGGTPVKIIKF
EECHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEEEH
ASDITAQKMRSIEDAGKIAAIGRVQAVIEFNLDGTIIDANDQFLGAMGYTLGEIKGRHHS
HHHHHHHHHHHHHHHCCEEHHEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCE
MFVLPHERDSVAYKEFWASLNRGEPRSGEYKRCGKDNREVWILASYNPILDDTGRPFKVV
EEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCEEEH
KYASDVTQQKLMAADFAGQIAAIRKSQAVIEFDMNGHVLDANDNFLKTLGYTLADIKGRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCC
HRMFMPPGAGESSEYREFWAALARGEFQSGEYERAGKGGRQVWIQATYNPIKDLNGKPFK
CEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEEEECCHHHCCCCCCEE
IVKFASDVTAQVITRMKGDKVRGMMEHVAAGAEQLNSSVQQIADAMAKSKETATAAVTRV
EEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DDADQQAKRLSSAAGAMSSIVELIGSITGQINLLALNATIESARAGEAGRGFAVVAGEVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCCEEEEHHHHH
NLANQAKQATDRIGSEIGNLNGISSDVVGALDAIKAAIQSVDAYVSSTAQAVGEQSAVTS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSSNMRQAAAEAATIGKAA
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFWSGSSASRDALAQVEAINRSQAVIEFGIDGTIITANKNFLDAMGYALDEIKGRHHRM
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCEE
FVAPQLRESAEYKAFWSDLKRGKFRSGEYKRFGKGERPVWIQASYNPVLDGGTPVKIIKF
EECHHHHHCCHHHHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEEEH
ASDITAQKMRSIEDAGKIAAIGRVQAVIEFNLDGTIIDANDQFLGAMGYTLGEIKGRHHS
HHHHHHHHHHHHHHHCCEEHHEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCCE
MFVLPHERDSVAYKEFWASLNRGEPRSGEYKRCGKDNREVWILASYNPILDDTGRPFKVV
EEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCEEEH
KYASDVTQQKLMAADFAGQIAAIRKSQAVIEFDMNGHVLDANDNFLKTLGYTLADIKGRH
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCC
HRMFMPPGAGESSEYREFWAALARGEFQSGEYERAGKGGRQVWIQATYNPIKDLNGKPFK
CEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEEEECCHHHCCCCCCEE
IVKFASDVTAQVITRMKGDKVRGMMEHVAAGAEQLNSSVQQIADAMAKSKETATAAVTRV
EEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DDADQQAKRLSSAAGAMSSIVELIGSITGQINLLALNATIESARAGEAGRGFAVVAGEVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHCCCCCCCCEEEEHHHHH
NLANQAKQATDRIGSEIGNLNGISSDVVGALDAIKAAIQSVDAYVSSTAQAVGEQSAVTS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMSSNMRQAAAEAATIGKAA
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]