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The map label for this gene is nagA [H]

Identifier: 146301712

GI number: 146301712

Start: 4759309

End: 4760433

Strand: Direct

Name: nagA [H]

Synonym: Fjoh_3974

Alternate gene names: 146301712

Gene position: 4759309-4760433 (Clockwise)

Preceding gene: 146301711

Following gene: 146301716

Centisome position: 78.06

GC content: 36.09

Gene sequence:

>1125_bases
ATGAAACAGGCAATTGTTAATGCCATAATACATACTGGTGACGAAATAATTGATAATGGAGTCATTATCATCGAAAACGG
AACTATTCTTTCTGTACAAAAAGAAATTCCGAATGATATAAAAACCATCGATCTGCAGGGAAAACATATTGGTGCCGGAT
TTATAGATATTCAGATAAACGGAGGAGAAAAACATTATTTCAGCCAGACTCCAAATGAAGAAACTATTCAGGATATTTAC
AATTCGAGTCTGAAATACGGAACAACACATGTTTTGCCCTGTTTAATTTCATCATCAAAAGAAACCATTTTACAAGGAAT
TGAAGCTGCCCGCAATTACATTAAAAAACACAATAATGGTGTAATTGGAATGCATTTAGAAGGACCTTTTTTAAATCCTT
TAAAACGCGGTGCGCACAGCATCGATCAGGTTCGTAAACCAACAAATGCTGAACTGGAAGAAATCATCAAACACGGAAAA
GACGTTATAAAAGTAATCACCATTGCTCCGGAATGTTTTACTGATGAACAATTAAATATGCTGCTGGAAAGCGGTATAAC
AATTTCTGCAGGACATTCTACAATGGGTTATAAAGAAGCACAGCATTATTTCTCAAAAGGAATCAATCTCGTTACCCATT
TATTCAACGCCATGACACAGTTTGGTCATCGTGAACCAGGTTTGGTTGGTGCTGTTTTTGAAAATGAAAAAGTGTATGCT
CCCATAATTTTAGACGGAGCACACTGCGATTATGCGGCCGCAAAAGTGGCTTACAAACTCAAACAGGAAAAATTCTTTTT
AATAAGCGACGCTACTTTCCTGGGACGCAAAGTAGAAAACTTTAAATGGGATAATTTTGATGCCCATTTAGAAAACGGTT
TTTACAGAAACGAAGACGGAAACTTAGCCGGTGCCACAATCTCGATGCTTGAAGCTGTACAAAATGCTTACAATCATTTA
AATGTTTCGGCAGATGAAGCCCTAAAAATGGCAACATCAAGAGTCGCAGCTGCCATAGGTTTAGAAAATAAAATTGGAAA
GATAAAAACAGGATTTCCTGCCAGTTTTGTAAAATTCAACGATAATTTATCAGAAATAGAAACCTTAAATTTTCCTGCTG
TATAA

Upstream 100 bases:

>100_bases
TCTTTTATTTTATTTTTAAATAAGATGACTTACGAATGATATTGATACATTTGTAATTCTGGAAATTCACTTTCAAATAA
AAATAAGAAACACAACTACA

Downstream 100 bases:

>100_bases
CAGCATTTAAATCATAAAAAAAGAGACAGTTAAAAACTGTCTCTTTTCAAATCAGAATTATTGTCAGCATTGCGTGCCGT
TCTAAACGTCTCAGTAACCT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKQAIVNAIIHTGDEIIDNGVIIIENGTILSVQKEIPNDIKTIDLQGKHIGAGFIDIQINGGEKHYFSQTPNEETIQDIY
NSSLKYGTTHVLPCLISSSKETILQGIEAARNYIKKHNNGVIGMHLEGPFLNPLKRGAHSIDQVRKPTNAELEEIIKHGK
DVIKVITIAPECFTDEQLNMLLESGITISAGHSTMGYKEAQHYFSKGINLVTHLFNAMTQFGHREPGLVGAVFENEKVYA
PIILDGAHCDYAAAKVAYKLKQEKFFLISDATFLGRKVENFKWDNFDAHLENGFYRNEDGNLAGATISMLEAVQNAYNHL
NVSADEALKMATSRVAAAIGLENKIGKIKTGFPASFVKFNDNLSEIETLNFPAV

Sequences:

>Translated_374_residues
MKQAIVNAIIHTGDEIIDNGVIIIENGTILSVQKEIPNDIKTIDLQGKHIGAGFIDIQINGGEKHYFSQTPNEETIQDIY
NSSLKYGTTHVLPCLISSSKETILQGIEAARNYIKKHNNGVIGMHLEGPFLNPLKRGAHSIDQVRKPTNAELEEIIKHGK
DVIKVITIAPECFTDEQLNMLLESGITISAGHSTMGYKEAQHYFSKGINLVTHLFNAMTQFGHREPGLVGAVFENEKVYA
PIILDGAHCDYAAAKVAYKLKQEKFFLISDATFLGRKVENFKWDNFDAHLENGFYRNEDGNLAGATISMLEAVQNAYNHL
NVSADEALKMATSRVAAAIGLENKIGKIKTGFPASFVKFNDNLSEIETLNFPAV
>Mature_374_residues
MKQAIVNAIIHTGDEIIDNGVIIIENGTILSVQKEIPNDIKTIDLQGKHIGAGFIDIQINGGEKHYFSQTPNEETIQDIY
NSSLKYGTTHVLPCLISSSKETILQGIEAARNYIKKHNNGVIGMHLEGPFLNPLKRGAHSIDQVRKPTNAELEEIIKHGK
DVIKVITIAPECFTDEQLNMLLESGITISAGHSTMGYKEAQHYFSKGINLVTHLFNAMTQFGHREPGLVGAVFENEKVYA
PIILDGAHCDYAAAKVAYKLKQEKFFLISDATFLGRKVENFKWDNFDAHLENGFYRNEDGNLAGATISMLEAVQNAYNHL
NVSADEALKMATSRVAAAIGLENKIGKIKTGFPASFVKFNDNLSEIETLNFPAV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=363, Percent_Identity=27.8236914600551, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI224922791, Length=365, Percent_Identity=27.9452054794521, Blast_Score=131, Evalue=9e-31,
Organism=Escherichia coli, GI1786892, Length=372, Percent_Identity=38.1720430107527, Blast_Score=257, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI17553768, Length=370, Percent_Identity=29.4594594594595, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI19920392, Length=349, Percent_Identity=34.9570200573066, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI281361140, Length=355, Percent_Identity=34.3661971830986, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41270; Mature: 41270

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAIVNAIIHTGDEIIDNGVIIIENGTILSVQKEIPNDIKTIDLQGKHIGAGFIDIQIN
CHHHHHHHHHHCCHHHHCCCEEEEECCEEEEEHHHCCCCCEEEEECCCEECCEEEEEEEE
GGEKHYFSQTPNEETIQDIYNSSLKYGTTHVLPCLISSSKETILQGIEAARNYIKKHNNG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VIGMHLEGPFLNPLKRGAHSIDQVRKPTNAELEEIIKHGKDVIKVITIAPECFTDEQLNM
EEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHEEEEEEECCCCCCHHHHHH
LLESGITISAGHSTMGYKEAQHYFSKGINLVTHLFNAMTQFGHREPGLVGAVFENEKVYA
HHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
PIILDGAHCDYAAAKVAYKLKQEKFFLISDATFLGRKVENFKWDNFDAHLENGFYRNEDG
EEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCHHHHCCCEEECCCC
NLAGATISMLEAVQNAYNHLNVSADEALKMATSRVAAAIGLENKIGKIKTGFPASFVKFN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
DNLSEIETLNFPAV
CCHHHHHCCCCCCC
>Mature Secondary Structure
MKQAIVNAIIHTGDEIIDNGVIIIENGTILSVQKEIPNDIKTIDLQGKHIGAGFIDIQIN
CHHHHHHHHHHCCHHHHCCCEEEEECCEEEEEHHHCCCCCEEEEECCCEECCEEEEEEEE
GGEKHYFSQTPNEETIQDIYNSSLKYGTTHVLPCLISSSKETILQGIEAARNYIKKHNNG
CCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VIGMHLEGPFLNPLKRGAHSIDQVRKPTNAELEEIIKHGKDVIKVITIAPECFTDEQLNM
EEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHEEEEEEECCCCCCHHHHHH
LLESGITISAGHSTMGYKEAQHYFSKGINLVTHLFNAMTQFGHREPGLVGAVFENEKVYA
HHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
PIILDGAHCDYAAAKVAYKLKQEKFFLISDATFLGRKVENFKWDNFDAHLENGFYRNEDG
EEEEECCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCHHHHCCCEEECCCC
NLAGATISMLEAVQNAYNHLNVSADEALKMATSRVAAAIGLENKIGKIKTGFPASFVKFN
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEC
DNLSEIETLNFPAV
CCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]