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The map label for this gene is ybbO [C]

Identifier: 146301631

GI number: 146301631

Start: 4638298

End: 4639293

Strand: Direct

Name: ybbO [C]

Synonym: Fjoh_3892

Alternate gene names: 146301631

Gene position: 4638298-4639293 (Clockwise)

Preceding gene: 146301630

Following gene: 146301632

Centisome position: 76.08

GC content: 40.16

Gene sequence:

>996_bases
ATGGAACAAAATAATTATCAAGGTGCCTTGCAGAAAAAGTTAAATTCAGGATTTAATGCAGCATCAACAGCAGAGGAAGT
TATAAAAGGAATCAATCTTGCAGGACAAACAGCAATTGTAACAGGCGGAAATACAGGCATAGGTCTCGAAACTGTTAAAA
CACTTGCTGCTGCAGGAGCTCATGTCATTGTACCGGCAAGAGACATTGTAAAAGCCAAAAGAAACCTTGAAGGAATAGAA
AATGTAACGATAGAAGAAATGGATTTAATGCAGCCAGAATCTATCCATTCCTTTGCACAGAAATTTATAAATACAGGAAG
ATCACTGCATCTTTTGATTAACAATGCCGGGATTATGTGGGTACCGCTTCGCAGAGACATACGCGGGTACGAATCACAGC
TGGCAACCAATTATCTCGCATTGTTTCAATTAACAGCCGGGCTTTGGCCGGCATTAAAAAAAGCAGACGGCGCCAGAGTG
GTTAATGTATCTTCTGGAGGACATAAATTTTCTGATTTTAATTTTGAAGATCCTAATTTCCTGAACCGTGAGTACGAAAC
ACTGCTTGGATACGGACAATCTAAAACAGCGGTCAATCTTTTTTCTTTGGAATTTGACAACCGCGCCAAAGCTTACAATG
TCCGCAGTTATTCCTTATGTCCAGGAGCAGTTGGAGAAACAGAATTATCGAGAGAAGCTCCCATTGATTTATTCCAAAAA
CTAGGTTTCAGCGATGCAGAAGGAAATATACTGCCAGAAGTAGCGGCCTCATTAAAAACCATTCCGCAGGGTGCGGCAAC
AAGTATATGGGCTGCAACGAGTCCGCTTCTAAATCATATAGGAGGAGTTTACTGTGAACACGTGGATATAGCTGAAATAA
ATGAAAATATGGCAGTTACAGGAGGTATTGCGACCTATTCATTAGACAAATCAAATGTTCAAAAATTATGGAAGCTCACG
GAACAGCTTACTGGAATTACATTTGATGTACGTTAA

Upstream 100 bases:

>100_bases
AACAGACGTTTAAACAAAGTATCTTAGGACGTTTAAACAAAACAAATCTTTGCTGTCACATCTAATTTTGTCTAATCATT
AATAATAAAAATTTAAAAAG

Downstream 100 bases:

>100_bases
ATTTGTATCTTTATAAACACATTCAAAATATGGATTATACGGTAAATTATATAACTCCGGAAATTAAACTTTCTAATTAT
ACTGGGAAGCTTTTTAAAAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEQNNYQGALQKKLNSGFNAASTAEEVIKGINLAGQTAIVTGGNTGIGLETVKTLAAAGAHVIVPARDIVKAKRNLEGIE
NVTIEEMDLMQPESIHSFAQKFINTGRSLHLLINNAGIMWVPLRRDIRGYESQLATNYLALFQLTAGLWPALKKADGARV
VNVSSGGHKFSDFNFEDPNFLNREYETLLGYGQSKTAVNLFSLEFDNRAKAYNVRSYSLCPGAVGETELSREAPIDLFQK
LGFSDAEGNILPEVAASLKTIPQGAATSIWAATSPLLNHIGGVYCEHVDIAEINENMAVTGGIATYSLDKSNVQKLWKLT
EQLTGITFDVR

Sequences:

>Translated_331_residues
MEQNNYQGALQKKLNSGFNAASTAEEVIKGINLAGQTAIVTGGNTGIGLETVKTLAAAGAHVIVPARDIVKAKRNLEGIE
NVTIEEMDLMQPESIHSFAQKFINTGRSLHLLINNAGIMWVPLRRDIRGYESQLATNYLALFQLTAGLWPALKKADGARV
VNVSSGGHKFSDFNFEDPNFLNREYETLLGYGQSKTAVNLFSLEFDNRAKAYNVRSYSLCPGAVGETELSREAPIDLFQK
LGFSDAEGNILPEVAASLKTIPQGAATSIWAATSPLLNHIGGVYCEHVDIAEINENMAVTGGIATYSLDKSNVQKLWKLT
EQLTGITFDVR
>Mature_331_residues
MEQNNYQGALQKKLNSGFNAASTAEEVIKGINLAGQTAIVTGGNTGIGLETVKTLAAAGAHVIVPARDIVKAKRNLEGIE
NVTIEEMDLMQPESIHSFAQKFINTGRSLHLLINNAGIMWVPLRRDIRGYESQLATNYLALFQLTAGLWPALKKADGARV
VNVSSGGHKFSDFNFEDPNFLNREYETLLGYGQSKTAVNLFSLEFDNRAKAYNVRSYSLCPGAVGETELSREAPIDLFQK
LGFSDAEGNILPEVAASLKTIPQGAATSIWAATSPLLNHIGGVYCEHVDIAEINENMAVTGGIATYSLDKSNVQKLWKLT
EQLTGITFDVR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI186928839, Length=308, Percent_Identity=32.1428571428571, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI166795268, Length=331, Percent_Identity=31.4199395770393, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI7706523, Length=280, Percent_Identity=31.7857142857143, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI10190746, Length=313, Percent_Identity=31.9488817891374, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI225579078, Length=210, Percent_Identity=37.1428571428571, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI193804850, Length=305, Percent_Identity=34.4262295081967, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI19923931, Length=246, Percent_Identity=29.6747967479675, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI146231950, Length=305, Percent_Identity=28.1967213114754, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI13375997, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193207620, Length=332, Percent_Identity=26.2048192771084, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71992402, Length=321, Percent_Identity=29.2834890965732, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17532791, Length=290, Percent_Identity=28.6206896551724, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532805, Length=332, Percent_Identity=28.6144578313253, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=320, Percent_Identity=28.125, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535059, Length=322, Percent_Identity=27.9503105590062, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32565532, Length=223, Percent_Identity=28.6995515695067, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17558006, Length=313, Percent_Identity=29.3929712460064, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324820, Length=277, Percent_Identity=28.5198555956679, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921754, Length=312, Percent_Identity=34.6153846153846, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573296, Length=301, Percent_Identity=35.5481727574751, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI161076371, Length=262, Percent_Identity=36.6412213740458, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI22024069, Length=304, Percent_Identity=33.8815789473684, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24586328, Length=311, Percent_Identity=33.4405144694534, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI20129347, Length=327, Percent_Identity=27.5229357798165, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24647946, Length=320, Percent_Identity=29.375, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45553409, Length=310, Percent_Identity=29.6774193548387, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647948, Length=310, Percent_Identity=29.6774193548387, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45554248, Length=215, Percent_Identity=35.8139534883721, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640117, Length=215, Percent_Identity=35.8139534883721, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24656154, Length=265, Percent_Identity=31.6981132075472, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19922628, Length=265, Percent_Identity=31.6981132075472, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24647931, Length=329, Percent_Identity=27.355623100304, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35936; Mature: 35936

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNNYQGALQKKLNSGFNAASTAEEVIKGINLAGQTAIVTGGNTGIGLETVKTLAAAGA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCC
HVIVPARDIVKAKRNLEGIENVTIEEMDLMQPESIHSFAQKFINTGRSLHLLINNAGIMW
EEEECCHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCEEE
VPLRRDIRGYESQLATNYLALFQLTAGLWPALKKADGARVVNVSSGGHKFSDFNFEDPNF
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCH
LNREYETLLGYGQSKTAVNLFSLEFDNRAKAYNVRSYSLCPGAVGETELSREAPIDLFQK
HHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCEECCCCCCCCCCCCCCCCCHHHHHH
LGFSDAEGNILPEVAASLKTIPQGAATSIWAATSPLLNHIGGVYCEHVDIAEINENMAVT
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHCCCCEEEE
GGIATYSLDKSNVQKLWKLTEQLTGITFDVR
CCEEEEECCHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MEQNNYQGALQKKLNSGFNAASTAEEVIKGINLAGQTAIVTGGNTGIGLETVKTLAAAGA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCC
HVIVPARDIVKAKRNLEGIENVTIEEMDLMQPESIHSFAQKFINTGRSLHLLINNAGIMW
EEEECCHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCEEE
VPLRRDIRGYESQLATNYLALFQLTAGLWPALKKADGARVVNVSSGGHKFSDFNFEDPNF
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCH
LNREYETLLGYGQSKTAVNLFSLEFDNRAKAYNVRSYSLCPGAVGETELSREAPIDLFQK
HHHHHHHHHCCCCCCCEEEEEEEEECCCCCEEECCEECCCCCCCCCCCCCCCCCHHHHHH
LGFSDAEGNILPEVAASLKTIPQGAATSIWAATSPLLNHIGGVYCEHVDIAEINENMAVT
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHCCCCEEEE
GGIATYSLDKSNVQKLWKLTEQLTGITFDVR
CCEEEEECCHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]