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The map label for this gene is chaA [C]

Identifier: 146301599

GI number: 146301599

Start: 4575835

End: 4576911

Strand: Direct

Name: chaA [C]

Synonym: Fjoh_3860

Alternate gene names: 146301599

Gene position: 4575835-4576911 (Clockwise)

Preceding gene: 146301589

Following gene: 146301600

Centisome position: 75.05

GC content: 35.47

Gene sequence:

>1077_bases
ATGAAACGATTATTACAATGGACTATTATCATTCCGGCATTATCATGGATCCTTTTCTTCAGCGGACTTATAGAGGGAAG
CAGTATTTTTCAAATTGCAGCTAGTATATTACTTATTTTAAGCGTTATGTCGGCTGTACACCATTCCGAAATAATAGCAG
AAAGAGTTGGAGAGCCTTACGGAACAATTATTTTGGCCATATCAATTACCGTAATAGAAGTTTCGATAATTATATCCTTA
ATGATGTCAGATGGCCCGGAAGCAGTTTCACTTGCCAGAGATACAGTATATGCGGCAACCATGCTTATTCTTAACGGAAT
TATTGGGCTCTGTCTTTTAATTGGAGGTTTAAAACATTATGAGCAGAATTTTTCTGCTTCTTCTGTAACCATTGGTTTAG
TATCCCTTATTTCAATTATAGTATTTACACTCGTATTTCCAACTTTTACAGAAAGTGTTTCAGGATCATATTATTCAGAA
CCGCAGCTTGTTTTTGCTTCTATTGCCTGCATAGTAATTTATTCCTCTTTTCTGTTTGCACAAACTACACGATACCGTCA
ATATTTCCTGACTGAGGGTGAGGATGAGAATGACGATACTGCTAAACGTATTACAATTGATACTAAAACATTCTATACCA
GTTTGGTATTTCTAATTGTCAGTTTAGGCATTGTAGTATTACTTGCTAAGACACTCTCACCTACTATCGAAAGTATTATT
GTGAGTTACAGACTTCCAAAAAGTCTGGTTGGAGTTATAATTGCCATTATTATTCTGCTGCCCGAAGCTGTGGCTGCTAT
TATCGCAGCAAGAAAAAACAGATTACAAACCAGTATAAATTTAGCTTTGGGTTCAGCTTTGGCAAGTATTGGATTAACGA
TTCCCAGCGTTGCGGCAGTCTGCATTATAATGGATATGCCCATTATATTAGGGCTCGATATTAAATCTATTGTTTTATTA
GCTTTATCTGTATTTACCGTAATGCTGTCACTTAGTAAAGGAAAGTCGAATATAGTTTACGGAGTTGTACTTCTGGTTAA
CTTATTTGCTTTTATTTTCCTTATGATATATCCGTAA

Upstream 100 bases:

>100_bases
TGTTTTTTTATCAATTCCGGCAAAAAAGCCCTATATTACAAATTGGGAAAGGCCAGTTTTGTTGGGATTTTGGCCAAATA
TTAATTTTTAAATTAAAAAA

Downstream 100 bases:

>100_bases
TTTTCTTTTTGCTGTATCTGCATCAAAGAACAAACTTTATGATTTGTTCTTTGATGCATTTTATTTTTTTAGAATCACTG
TCCTTTTTCACTGCACACAA

Product: sodium/calcium exchanger membrane region

Products: Na (I) [Periplasm]; Ca (II) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKRLLQWTIIIPALSWILFFSGLIEGSSIFQIAASILLILSVMSAVHHSEIIAERVGEPYGTIILAISITVIEVSIIISL
MMSDGPEAVSLARDTVYAATMLILNGIIGLCLLIGGLKHYEQNFSASSVTIGLVSLISIIVFTLVFPTFTESVSGSYYSE
PQLVFASIACIVIYSSFLFAQTTRYRQYFLTEGEDENDDTAKRITIDTKTFYTSLVFLIVSLGIVVLLAKTLSPTIESII
VSYRLPKSLVGVIIAIIILLPEAVAAIIAARKNRLQTSINLALGSALASIGLTIPSVAAVCIIMDMPIILGLDIKSIVLL
ALSVFTVMLSLSKGKSNIVYGVVLLVNLFAFIFLMIYP

Sequences:

>Translated_358_residues
MKRLLQWTIIIPALSWILFFSGLIEGSSIFQIAASILLILSVMSAVHHSEIIAERVGEPYGTIILAISITVIEVSIIISL
MMSDGPEAVSLARDTVYAATMLILNGIIGLCLLIGGLKHYEQNFSASSVTIGLVSLISIIVFTLVFPTFTESVSGSYYSE
PQLVFASIACIVIYSSFLFAQTTRYRQYFLTEGEDENDDTAKRITIDTKTFYTSLVFLIVSLGIVVLLAKTLSPTIESII
VSYRLPKSLVGVIIAIIILLPEAVAAIIAARKNRLQTSINLALGSALASIGLTIPSVAAVCIIMDMPIILGLDIKSIVLL
ALSVFTVMLSLSKGKSNIVYGVVLLVNLFAFIFLMIYP
>Mature_358_residues
MKRLLQWTIIIPALSWILFFSGLIEGSSIFQIAASILLILSVMSAVHHSEIIAERVGEPYGTIILAISITVIEVSIIISL
MMSDGPEAVSLARDTVYAATMLILNGIIGLCLLIGGLKHYEQNFSASSVTIGLVSLISIIVFTLVFPTFTESVSGSYYSE
PQLVFASIACIVIYSSFLFAQTTRYRQYFLTEGEDENDDTAKRITIDTKTFYTSLVFLIVSLGIVVLLAKTLSPTIESII
VSYRLPKSLVGVIIAIIILLPEAVAAIIAARKNRLQTSINLALGSALASIGLTIPSVAAVCIIMDMPIILGLDIKSIVLL
ALSVFTVMLSLSKGKSNIVYGVVLLVNLFAFIFLMIYP

Specific function: Possible cation transporter [H]

COG id: COG0387

COG function: function code P; Ca2+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1787468, Length=365, Percent_Identity=29.8630136986301, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320075, Length=363, Percent_Identity=23.4159779614325, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004713
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 38740; Mature: 38740

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLQWTIIIPALSWILFFSGLIEGSSIFQIAASILLILSVMSAVHHSEIIAERVGEPY
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
GTIILAISITVIEVSIIISLMMSDGPEAVSLARDTVYAATMLILNGIIGLCLLIGGLKHY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQNFSASSVTIGLVSLISIIVFTLVFPTFTESVSGSYYSEPQLVFASIACIVIYSSFLFA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QTTRYRQYFLTEGEDENDDTAKRITIDTKTFYTSLVFLIVSLGIVVLLAKTLSPTIESII
HHHHHHHHHCCCCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSYRLPKSLVGVIIAIIILLPEAVAAIIAARKNRLQTSINLALGSALASIGLTIPSVAAV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CIIMDMPIILGLDIKSIVLLALSVFTVMLSLSKGKSNIVYGVVLLVNLFAFIFLMIYP
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRLLQWTIIIPALSWILFFSGLIEGSSIFQIAASILLILSVMSAVHHSEIIAERVGEPY
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
GTIILAISITVIEVSIIISLMMSDGPEAVSLARDTVYAATMLILNGIIGLCLLIGGLKHY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQNFSASSVTIGLVSLISIIVFTLVFPTFTESVSGSYYSEPQLVFASIACIVIYSSFLFA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QTTRYRQYFLTEGEDENDDTAKRITIDTKTFYTSLVFLIVSLGIVVLLAKTLSPTIESII
HHHHHHHHHCCCCCCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSYRLPKSLVGVIIAIIILLPEAVAAIIAARKNRLQTSINLALGSALASIGLTIPSVAAV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
CIIMDMPIILGLDIKSIVLLALSVFTVMLSLSKGKSNIVYGVVLLVNLFAFIFLMIYP
HHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Cytoplasm]; Proton [Periplasm]; Ca (II) [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: Na (I) [Cytoplasm] + Proton [Periplasm] = Proton [Cytoplasm] + Na (I) [Periplasm] Ca (II) [Cytoplasm] + Proton [Periplasm] = Ca (II) [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]