Click here to switch to the map view.

The map label for this gene is ctpB [H]

Identifier: 146301592

GI number: 146301592

Start: 4565642

End: 4566994

Strand: Reverse

Name: ctpB [H]

Synonym: Fjoh_3853

Alternate gene names: 146301592

Gene position: 4566994-4565642 (Counterclockwise)

Preceding gene: 146301593

Following gene: 146301591

Centisome position: 74.91

GC content: 35.62

Gene sequence:

>1353_bases
ATGAGATATACCAAAATTACATTCTTGTCGATGCTTCTTTTTTTATCTGTTTTTATATTCTCATGTTCAGATAACGATTC
TTCTGCTCCGGTTTATGAAGAAGGCACAAATGAATATGTAAATGAGTGGATGTATCAGCAGATGAAAAGATATTATCTCT
GGAATACTTCAATGTCACAAAAAGGCAGTTTGTCTATTTTTCCTCAGGATTATTTTGCGGGTCTTCTCGAAAAGGGAGAC
AGATATTCTTATGCTGTGCATCCCGAACTTCCTGAAACAGCAGGGCAAAGCTTAAGACGTAAATTTGGATTTGACGTTTC
CTTTTTTGAATTTGAAGCAAAATATTATGCCGTTATTCTATATGTGCTCGAAGATTCTCCTGCTAAAAGAAACGGTTTAA
AAAGAGGACAGCTTATCACAAAAGTAGAAGGAACGCCGCTGAACCAGAATAATTACGATGAACTGTATTTAAAAATGACA
TCGGCTTCACAGCTTAACATACAAACCGTTTCTTATACAGCACAAACCGGATTTTCTAATTTAAAAGAAGTTTCAATACT
TCAGGGGTATACATTTTCACAGCCTGTAAAATATACAGTTATTGAAGATAAAAGCAAAAAAATCGGATACGTCGAAATCT
CTCATTTTGATGTGGGGCAGGCACAGTTATTTCTTCAGACTTTTCAGGAATTAAAAAATAAATCAATTACAGAACTTGTT
GTAGACTTGCGGTATAACGGAGGCGGGGATATCGCGTCTGCTGCAGCATTGAGTATTATTCTGGCTCCGGATATTCAGTC
TGGCAGTCTTTTTATAAAATTTGAAGGAAATACTAACGGCGGAAAAGTTGATCAGTCATTTAAAGAAGCTTTAGCAGGCA
ACGAATCTAAAATAAGTTTTGAGGCACTGCGCGGCGCACATCCTTCTATAAACAAAGTTTATATTTTATGCGGTAAACAT
ACAGCATCCGCTTCAGAGCTTATTATAAACAATTTAAAACCTTATATGGAAGTTATAACGATTGGTGATAAAACATTTGG
CAAAGATGTTGCCGGTTTTCCAATCGAAGATGATAGAATATCAGGCAAGAAAGGCTGGACTTTGTATCCTGCAATATATA
AAATATTCAATTCAAGACACGAAGGCAATTATTCGCAGGGAATTGACCCGCTCATTTCTGTAAATGAAATTCAGCAGCCA
GAAGTTTTTCCATTAGGAAACAGTTCGGAAATCTTATTAGCCAAAGCTTTAAATTCTATTACCGGAAATACAGCCAAAAC
CTTTTCTCCCTCAGTAAAATGCTTTCCCATTTCAGTAAATAAATCAGATACTGACTTTTTGATAATTCACTAA

Upstream 100 bases:

>100_bases
TGCTTTTTCTGGTGTAGATGGTATTTTGAACCTTACGGATTATTTTGTTTTTAAATAATTCATTACGAATATAAAAACGA
TACTAATAACTAAACTATAA

Downstream 100 bases:

>100_bases
TTCTTAAAAAATATTTTATATAATTATGCAGGGCATTGATAAAAGAGAACATCGAAATCTGGAAGATGTTTTTAAAAAAT
ATAAAAACAGTTATCATAAT

Product: peptidase S41

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRYTKITFLSMLLFLSVFIFSCSDNDSSAPVYEEGTNEYVNEWMYQQMKRYYLWNTSMSQKGSLSIFPQDYFAGLLEKGD
RYSYAVHPELPETAGQSLRRKFGFDVSFFEFEAKYYAVILYVLEDSPAKRNGLKRGQLITKVEGTPLNQNNYDELYLKMT
SASQLNIQTVSYTAQTGFSNLKEVSILQGYTFSQPVKYTVIEDKSKKIGYVEISHFDVGQAQLFLQTFQELKNKSITELV
VDLRYNGGGDIASAAALSIILAPDIQSGSLFIKFEGNTNGGKVDQSFKEALAGNESKISFEALRGAHPSINKVYILCGKH
TASASELIINNLKPYMEVITIGDKTFGKDVAGFPIEDDRISGKKGWTLYPAIYKIFNSRHEGNYSQGIDPLISVNEIQQP
EVFPLGNSSEILLAKALNSITGNTAKTFSPSVKCFPISVNKSDTDFLIIH

Sequences:

>Translated_450_residues
MRYTKITFLSMLLFLSVFIFSCSDNDSSAPVYEEGTNEYVNEWMYQQMKRYYLWNTSMSQKGSLSIFPQDYFAGLLEKGD
RYSYAVHPELPETAGQSLRRKFGFDVSFFEFEAKYYAVILYVLEDSPAKRNGLKRGQLITKVEGTPLNQNNYDELYLKMT
SASQLNIQTVSYTAQTGFSNLKEVSILQGYTFSQPVKYTVIEDKSKKIGYVEISHFDVGQAQLFLQTFQELKNKSITELV
VDLRYNGGGDIASAAALSIILAPDIQSGSLFIKFEGNTNGGKVDQSFKEALAGNESKISFEALRGAHPSINKVYILCGKH
TASASELIINNLKPYMEVITIGDKTFGKDVAGFPIEDDRISGKKGWTLYPAIYKIFNSRHEGNYSQGIDPLISVNEIQQP
EVFPLGNSSEILLAKALNSITGNTAKTFSPSVKCFPISVNKSDTDFLIIH
>Mature_450_residues
MRYTKITFLSMLLFLSVFIFSCSDNDSSAPVYEEGTNEYVNEWMYQQMKRYYLWNTSMSQKGSLSIFPQDYFAGLLEKGD
RYSYAVHPELPETAGQSLRRKFGFDVSFFEFEAKYYAVILYVLEDSPAKRNGLKRGQLITKVEGTPLNQNNYDELYLKMT
SASQLNIQTVSYTAQTGFSNLKEVSILQGYTFSQPVKYTVIEDKSKKIGYVEISHFDVGQAQLFLQTFQELKNKSITELV
VDLRYNGGGDIASAAALSIILAPDIQSGSLFIKFEGNTNGGKVDQSFKEALAGNESKISFEALRGAHPSINKVYILCGKH
TASASELIINNLKPYMEVITIGDKTFGKDVAGFPIEDDRISGKKGWTLYPAIYKIFNSRHEGNYSQGIDPLISVNEIQQP
EVFPLGNSSEILLAKALNSITGNTAKTFSPSVKCFPISVNKSDTDFLIIH

Specific function: Involved in the signal transduction pathway leading to the proteolytic activation of the mother cell transcription factor pro-sigma-K during sporulation. The signaling serine protease CtpB triggers pro-sigma-K processing by cleaving the regulatory protein

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Forespore intermembrane space. Note=Is expressed in both the mother cell and forespore compartments but that synthesis in the forespore is both necessary and sufficient for the proper timing of pro-sigma-K processing [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 50375; Mature: 50375

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYTKITFLSMLLFLSVFIFSCSDNDSSAPVYEEGTNEYVNEWMYQQMKRYYLWNTSMSQ
CCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCC
KGSLSIFPQDYFAGLLEKGDRYSYAVHPELPETAGQSLRRKFGFDVSFFEFEAKYYAVIL
CCCEEECCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEEE
YVLEDSPAKRNGLKRGQLITKVEGTPLNQNNYDELYLKMTSASQLNIQTVSYTAQTGFSN
EEEECCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEEEHHCCCCH
LKEVSILQGYTFSQPVKYTVIEDKSKKIGYVEISHFDVGQAQLFLQTFQELKNKSITELV
HHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
VDLRYNGGGDIASAAALSIILAPDIQSGSLFIKFEGNTNGGKVDQSFKEALAGNESKISF
EEEEECCCCCHHHHHEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEH
EALRGAHPSINKVYILCGKHTASASELIINNLKPYMEVITIGDKTFGKDVAGFPIEDDRI
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
SGKKGWTLYPAIYKIFNSRHEGNYSQGIDPLISVNEIQQPEVFPLGNSSEILLAKALNSI
CCCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCHHHHHHHHH
TGNTAKTFSPSVKCFPISVNKSDTDFLIIH
CCCCCCCCCCCEEEEEEEECCCCCCEEEEC
>Mature Secondary Structure
MRYTKITFLSMLLFLSVFIFSCSDNDSSAPVYEEGTNEYVNEWMYQQMKRYYLWNTSMSQ
CCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCC
KGSLSIFPQDYFAGLLEKGDRYSYAVHPELPETAGQSLRRKFGFDVSFFEFEAKYYAVIL
CCCEEECCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEEE
YVLEDSPAKRNGLKRGQLITKVEGTPLNQNNYDELYLKMTSASQLNIQTVSYTAQTGFSN
EEEECCCCHHCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEEEEEHHCCCCH
LKEVSILQGYTFSQPVKYTVIEDKSKKIGYVEISHFDVGQAQLFLQTFQELKNKSITELV
HHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
VDLRYNGGGDIASAAALSIILAPDIQSGSLFIKFEGNTNGGKVDQSFKEALAGNESKISF
EEEEECCCCCHHHHHEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCEEH
EALRGAHPSINKVYILCGKHTASASELIINNLKPYMEVITIGDKTFGKDVAGFPIEDDRI
HHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
SGKKGWTLYPAIYKIFNSRHEGNYSQGIDPLISVNEIQQPEVFPLGNSSEILLAKALNSI
CCCCCCEEHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCHHHHHHHHH
TGNTAKTFSPSVKCFPISVNKSDTDFLIIH
CCCCCCCCCCCEEEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9570401; 9384377 [H]