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The map label for this gene is xseA [H]

Identifier: 146301514

GI number: 146301514

Start: 4473576

End: 4475012

Strand: Reverse

Name: xseA [H]

Synonym: Fjoh_3775

Alternate gene names: 146301514

Gene position: 4475012-4473576 (Counterclockwise)

Preceding gene: 146301519

Following gene: 146301513

Centisome position: 73.4

GC content: 44.33

Gene sequence:

>1437_bases
ATGCAGCCAGTCCAGTATATAAAACTCTCACAGCTCAACGACCAGATCCAGGATACGATCAATGCCCGCTTTAAGGGACA
GACCTACTGGGTAGTGGCCGATATTACCAATCATTCTTTTAAAGCGGATAAAAAGATCCATTATTTTGAGCTGGTTGAGA
AATCAGATAAAAGCAGTGCGATCACAGCAAAAATAATGGGCAAGAGCTGGGGATCCGGAGCACTGAGGATCCTTGATTTT
GAAAGCAGCACCGGACAGCGCTTTACCAACAACCTGCATGTGCTGGTGCAGGTAAGCGTGGATTTTCATCCGCTGTACGG
CCTTTCGGTGAACCTTCTGGATATCGACAGCAGTTTTATGCTGGGGATTTTGGAACAGCAGCGCAACGCGACACTTGAGA
GGCTTGTAAAAGAAAATGATTTTATACACAAAGAAGGTGATGGGTACTCTACGCTGAACAGCCGTCTTAAACTTGGGGCA
GTAATCCAGAGAGTTGCGGTCATTTCTTCGAGCAGTTCAGCAGGAAACGAGGATTTCCGCCACACCATGCAGCATAATGA
TTTTGGCTATGTTTTCCAGATCGATGACTATCACACCGTTGTTCAGGGGGACAATAATGCCAAACTTTTTTTAAACAAGC
TTATTGAGGTCTACAATACTGGGATTCCTTACGATGTCATTGTTATTACAAGAGGCGGCGGATCACAGTCCGATTTTCTG
ATTTTTGACAATTACAATATTGGAAGGGCTGTCGCTAAATTCCCTATTCCTGTTATAACCGGCATCGGGCACCAGAAAAA
TATCAGCATTACCGACCTCATGGCCCATACCCATACTAAAACGCCAACCAAGGCCGCGGAGTTCATCATTGCCCATAACA
GGAGTTTTGAGCTGGGAATACTAGCGCTGCAGAAAAACATCGTCATAAAATCCCAGCAGCTTTTTCTGCAATATCATAAC
GAGCTTAACAGTCTTAAAAATGCTGTTGCCCATAATGCCAGGAAATTGATCTCAGTGCAGAAAGAAGAACTGATGATGGC
CCGGCAGCATATTGTTCAGACAGGAAGATCCCTGTTAAATGACAAGAAACAGCAGCTGCTTTTAACGGCGCAGCTTACCC
TACAGCGGCCGCAGGGTATCATCCAGCAGAAAAACAGTAATCTGCGGCACTTAAAAGCAAACTTAAAGATTTTTACCAGC
CATTACCTGCGCAGCCGCAAACTGCAATTGGAGGACTGCCGGAAAACCATAAAACTGCTCTCTCCGCAGCATGTACTGAG
CAGAGGGTATGCTGTTGTACGGGTTCATGATAAAATTATAAACGGAGCCGGCAGTATACAAGAAGGAGAGCAGATTGAAA
TACTATTAAAAGATGCCATACTGAAAAGTACGGTCAATGAAAAAATTCATTATGATGGAAAACACACTGACTTATGA

Upstream 100 bases:

>100_bases
ATCCTAAAGAGTACTTTGGAGATTGCGTTGTATTATTAGTACCTTAGCAGAAATAAAAACAAGCAGAGAAAAAACATAAA
GTGCAGCCTTGAAGAAAACT

Downstream 100 bases:

>100_bases
GGCAGCTGCCAAAGAACTGGCATTAATTGCCAAAGAAATGGAAGATGAAACGATCTCTGTGGATGAGCTGGCTGCCAAAG
TCAAAAGAGCATCTGAACTC

Product: exodeoxyribonuclease VII

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MQPVQYIKLSQLNDQIQDTINARFKGQTYWVVADITNHSFKADKKIHYFELVEKSDKSSAITAKIMGKSWGSGALRILDF
ESSTGQRFTNNLHVLVQVSVDFHPLYGLSVNLLDIDSSFMLGILEQQRNATLERLVKENDFIHKEGDGYSTLNSRLKLGA
VIQRVAVISSSSSAGNEDFRHTMQHNDFGYVFQIDDYHTVVQGDNNAKLFLNKLIEVYNTGIPYDVIVITRGGGSQSDFL
IFDNYNIGRAVAKFPIPVITGIGHQKNISITDLMAHTHTKTPTKAAEFIIAHNRSFELGILALQKNIVIKSQQLFLQYHN
ELNSLKNAVAHNARKLISVQKEELMMARQHIVQTGRSLLNDKKQQLLLTAQLTLQRPQGIIQQKNSNLRHLKANLKIFTS
HYLRSRKLQLEDCRKTIKLLSPQHVLSRGYAVVRVHDKIINGAGSIQEGEQIEILLKDAILKSTVNEKIHYDGKHTDL

Sequences:

>Translated_478_residues
MQPVQYIKLSQLNDQIQDTINARFKGQTYWVVADITNHSFKADKKIHYFELVEKSDKSSAITAKIMGKSWGSGALRILDF
ESSTGQRFTNNLHVLVQVSVDFHPLYGLSVNLLDIDSSFMLGILEQQRNATLERLVKENDFIHKEGDGYSTLNSRLKLGA
VIQRVAVISSSSSAGNEDFRHTMQHNDFGYVFQIDDYHTVVQGDNNAKLFLNKLIEVYNTGIPYDVIVITRGGGSQSDFL
IFDNYNIGRAVAKFPIPVITGIGHQKNISITDLMAHTHTKTPTKAAEFIIAHNRSFELGILALQKNIVIKSQQLFLQYHN
ELNSLKNAVAHNARKLISVQKEELMMARQHIVQTGRSLLNDKKQQLLLTAQLTLQRPQGIIQQKNSNLRHLKANLKIFTS
HYLRSRKLQLEDCRKTIKLLSPQHVLSRGYAVVRVHDKIINGAGSIQEGEQIEILLKDAILKSTVNEKIHYDGKHTDL
>Mature_478_residues
MQPVQYIKLSQLNDQIQDTINARFKGQTYWVVADITNHSFKADKKIHYFELVEKSDKSSAITAKIMGKSWGSGALRILDF
ESSTGQRFTNNLHVLVQVSVDFHPLYGLSVNLLDIDSSFMLGILEQQRNATLERLVKENDFIHKEGDGYSTLNSRLKLGA
VIQRVAVISSSSSAGNEDFRHTMQHNDFGYVFQIDDYHTVVQGDNNAKLFLNKLIEVYNTGIPYDVIVITRGGGSQSDFL
IFDNYNIGRAVAKFPIPVITGIGHQKNISITDLMAHTHTKTPTKAAEFIIAHNRSFELGILALQKNIVIKSQQLFLQYHN
ELNSLKNAVAHNARKLISVQKEELMMARQHIVQTGRSLLNDKKQQLLLTAQLTLQRPQGIIQQKNSNLRHLKANLKIFTS
HYLRSRKLQLEDCRKTIKLLSPQHVLSRGYAVVRVHDKIINGAGSIQEGEQIEILLKDAILKSTVNEKIHYDGKHTDL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=326, Percent_Identity=25.4601226993865, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 54086; Mature: 54086

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVQYIKLSQLNDQIQDTINARFKGQTYWVVADITNHSFKADKKIHYFELVEKSDKSSA
CCCHHHEEHHHHHHHHHHHHCCEECCCEEEEEEEECCCCCCCCCCEEEHHHHHCCCCCCE
ITAKIMGKSWGSGALRILDFESSTGQRFTNNLHVLVQVSVDFHPLYGLSVNLLDIDSSFM
EEEEEECCCCCCCCEEEEEECCCCCCHHCCCEEEEEEEEECEEEECCCEEEEEECCCHHH
LGILEQQRNATLERLVKENDFIHKEGDGYSTLNSRLKLGAVIQRVAVISSSSSAGNEDFR
HHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
HTMQHNDFGYVFQIDDYHTVVQGDNNAKLFLNKLIEVYNTGIPYDVIVITRGGGSQSDFL
HHHCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
IFDNYNIGRAVAKFPIPVITGIGHQKNISITDLMAHTHTKTPTKAAEFIIAHNRSFELGI
EEECCCCCHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCHHEEEEEEECCCCEEEE
LALQKNIVIKSQQLFLQYHNELNSLKNAVAHNARKLISVQKEELMMARQHIVQTGRSLLN
EEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKKQQLLLTAQLTLQRPQGIIQQKNSNLRHLKANLKIFTSHYLRSRKLQLEDCRKTIKLL
CHHHHEEEEEEEHHCCCCHHHHCCCCCCEEEEECHHHEEHHHHHHCCCCHHHHHHHHHHC
SPQHVLSRGYAVVRVHDKIINGAGSIQEGEQIEILLKDAILKSTVNEKIHYDGKHTDL
CHHHHHHCCEEEEEEEEHHHCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MQPVQYIKLSQLNDQIQDTINARFKGQTYWVVADITNHSFKADKKIHYFELVEKSDKSSA
CCCHHHEEHHHHHHHHHHHHCCEECCCEEEEEEEECCCCCCCCCCEEEHHHHHCCCCCCE
ITAKIMGKSWGSGALRILDFESSTGQRFTNNLHVLVQVSVDFHPLYGLSVNLLDIDSSFM
EEEEEECCCCCCCCEEEEEECCCCCCHHCCCEEEEEEEEECEEEECCCEEEEEECCCHHH
LGILEQQRNATLERLVKENDFIHKEGDGYSTLNSRLKLGAVIQRVAVISSSSSAGNEDFR
HHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
HTMQHNDFGYVFQIDDYHTVVQGDNNAKLFLNKLIEVYNTGIPYDVIVITRGGGSQSDFL
HHHCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEE
IFDNYNIGRAVAKFPIPVITGIGHQKNISITDLMAHTHTKTPTKAAEFIIAHNRSFELGI
EEECCCCCHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCHHEEEEEEECCCCEEEE
LALQKNIVIKSQQLFLQYHNELNSLKNAVAHNARKLISVQKEELMMARQHIVQTGRSLLN
EEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DKKQQLLLTAQLTLQRPQGIIQQKNSNLRHLKANLKIFTSHYLRSRKLQLEDCRKTIKLL
CHHHHEEEEEEEHHCCCCHHHHCCCCCCEEEEECHHHEEHHHHHHCCCCHHHHHHHHHHC
SPQHVLSRGYAVVRVHDKIINGAGSIQEGEQIEILLKDAILKSTVNEKIHYDGKHTDL
CHHHHHHCCEEEEEEEEHHHCCCCCCCCCCEEEEHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA