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The map label for this gene is dinB [H]

Identifier: 146301507

GI number: 146301507

Start: 4464745

End: 4465929

Strand: Direct

Name: dinB [H]

Synonym: Fjoh_3768

Alternate gene names: 146301507

Gene position: 4464745-4465929 (Clockwise)

Preceding gene: 146301505

Following gene: 146301508

Centisome position: 73.23

GC content: 46.41

Gene sequence:

>1185_bases
ATGAACCGGGCCATTGTACATATTGACATGAACACGTTCTTCGTATCGTGTGAAAGACTGACGAATTCTGAACTTAACGG
CATTCCGCTTATTATTGGCGGCGGTGATAGAGGTGTCGTGGCATCGTGTTCGTATGAGGCACGCCGTTTTGGGGTTCGTT
CTGCCATGCCGATTCATATGGCTATGAAGTTATGTCCTCAGGCCAAAATCATGAAAGGCGACATGGAACTCTATTCAAGG
CTCTCCCATGAGGTTACTGAAATTATCCAGGAAAAAGCGCCTGTGGTTGAAAAAGCCAGCATAGATGAATTTTATCTGGA
CATAACCGGAATGGATAAATTCTACGGCAGTTATAAATGGACCGATGAACTCGCCCAACGCATTACAAAAGAAACCGGCC
TTCCCCTCACCTTTGCGCTTTCGGTTAACAAAACCGTTTCTAAAATCGGCACAGGGGAAGGAAAGCAGAAACAGAACCTT
GAAATCCCGCAGCAGCTGGTCCAGTCTTTTTTAAATCCGCTTTCTATCCGTAAAATCCCGATGGTGGGTGAAAAGACATT
TCAGCTCCTTTCCCGGATCGGGATCAGGAAAATCCAGACCCTTTCCGAAATGCCGGCTGAAGCGCTCCAGCGGATGATCG
GCCAGAACGGAATCGAGCTCTGGAAAAAAGCCAATGGTATTGATAATAATCCGGTAGAACCCTACACGGAAAGAAAATCT
ATTTCCACTGAACATACCTTCTCCCAGGATACGATTGACATACCAAAGCTGAACAGGGTGCTGCTGGGGATGGTAGAAAA
ACTCTCTTACCAGCTCCGTTCCGAACAGTGGCTCACATCAACTGTAACGGTTAAAATCCGATATGCCAACTTTGATACCG
AAACCAAACAATGCCGTGTGCAGTATACCTCTGCGGATCATATCCTGACCCAGACCGTAACGGAATTGTTTGACAAACTC
TATCAGCGCCGTATGAGGCTGCGTCTTATCGGGGTGCGTTTCAGCGGGCTGGTGAGAGGGACCTATCAGATTGATCTTTT
CAATGATACTGAAGAAATGCTGGCGCTCTATCAGGCTATGGACCGCATGAAAAACCGTTACGGCTTTGATGCGGTAATGC
GCTGTGCCGGCGCTTCTTTCAAACCCAACAATAAAAATGAAATTTTAAAACGTAAATCAGACTAA

Upstream 100 bases:

>100_bases
AAAATAAGGATTTTAAAATTTTGTTATTATTTAGAACATTTTATTTTTAAAAAATGTTCTTATCTGTACTAATTTTGATC
TGTATAAAAATGAACAGATC

Downstream 100 bases:

>100_bases
ATGTATCTCAACTGCCACTCTTTCCACTCGCTGCGTTACGGCACTATTCCGGTTGAGGAATTGGTGCAGCTGGCTGTGTC
GCTGGGTGTTCAAGCCATGG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGDRGVVASCSYEARRFGVRSAMPIHMAMKLCPQAKIMKGDMELYSR
LSHEVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSVNKTVSKIGTGEGKQKQNL
EIPQQLVQSFLNPLSIRKIPMVGEKTFQLLSRIGIRKIQTLSEMPAEALQRMIGQNGIELWKKANGIDNNPVEPYTERKS
ISTEHTFSQDTIDIPKLNRVLLGMVEKLSYQLRSEQWLTSTVTVKIRYANFDTETKQCRVQYTSADHILTQTVTELFDKL
YQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKNRYGFDAVMRCAGASFKPNNKNEILKRKSD

Sequences:

>Translated_394_residues
MNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGDRGVVASCSYEARRFGVRSAMPIHMAMKLCPQAKIMKGDMELYSR
LSHEVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSVNKTVSKIGTGEGKQKQNL
EIPQQLVQSFLNPLSIRKIPMVGEKTFQLLSRIGIRKIQTLSEMPAEALQRMIGQNGIELWKKANGIDNNPVEPYTERKS
ISTEHTFSQDTIDIPKLNRVLLGMVEKLSYQLRSEQWLTSTVTVKIRYANFDTETKQCRVQYTSADHILTQTVTELFDKL
YQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKNRYGFDAVMRCAGASFKPNNKNEILKRKSD
>Mature_394_residues
MNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGDRGVVASCSYEARRFGVRSAMPIHMAMKLCPQAKIMKGDMELYSR
LSHEVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKWTDELAQRITKETGLPLTFALSVNKTVSKIGTGEGKQKQNL
EIPQQLVQSFLNPLSIRKIPMVGEKTFQLLSRIGIRKIQTLSEMPAEALQRMIGQNGIELWKKANGIDNNPVEPYTERKS
ISTEHTFSQDTIDIPKLNRVLLGMVEKLSYQLRSEQWLTSTVTVKIRYANFDTETKQCRVQYTSADHILTQTVTELFDKL
YQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAMDRMKNRYGFDAVMRCAGASFKPNNKNEILKRKSD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=358, Percent_Identity=24.3016759776536, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI5729982, Length=330, Percent_Identity=26.969696969697, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI84043967, Length=275, Percent_Identity=25.8181818181818, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI7706681, Length=275, Percent_Identity=25.8181818181818, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=40.3669724770642, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1786425, Length=300, Percent_Identity=31.3333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787432, Length=367, Percent_Identity=21.2534059945504, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=109, Percent_Identity=33.9449541284404, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17537959, Length=387, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=34.4, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19923006, Length=433, Percent_Identity=22.8637413394919, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21355641, Length=336, Percent_Identity=20.8333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644984, Length=336, Percent_Identity=20.8333333333333, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45056; Mature: 45056

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGDRGVVASCSYEARRFGVRSAMPIHM
CCCEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCCHHHH
AMKLCPQAKIMKGDMELYSRLSHEVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCCCC
TDELAQRITKETGLPLTFALSVNKTVSKIGTGEGKQKQNLEIPQQLVQSFLNPLSIRKIP
HHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
MVGEKTFQLLSRIGIRKIQTLSEMPAEALQRMIGQNGIELWKKANGIDNNPVEPYTERKS
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHCC
ISTEHTFSQDTIDIPKLNRVLLGMVEKLSYQLRSEQWLTSTVTVKIRYANFDTETKQCRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEEEE
QYTSADHILTQTVTELFDKLYQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAM
EECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCEEEEEEEEEEECCHHHHHHHHHHH
DRMKNRYGFDAVMRCAGASFKPNNKNEILKRKSD
HHHHHHCCHHHHHHHCCCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MNRAIVHIDMNTFFVSCERLTNSELNGIPLIIGGGDRGVVASCSYEARRFGVRSAMPIHM
CCCEEEEEECHHHEEEHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHCCCCCCHHHH
AMKLCPQAKIMKGDMELYSRLSHEVTEIIQEKAPVVEKASIDEFYLDITGMDKFYGSYKW
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCHHHHCCCCC
TDELAQRITKETGLPLTFALSVNKTVSKIGTGEGKQKQNLEIPQQLVQSFLNPLSIRKIP
HHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
MVGEKTFQLLSRIGIRKIQTLSEMPAEALQRMIGQNGIELWKKANGIDNNPVEPYTERKS
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHCC
ISTEHTFSQDTIDIPKLNRVLLGMVEKLSYQLRSEQWLTSTVTVKIRYANFDTETKQCRV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCEEEE
QYTSADHILTQTVTELFDKLYQRRMRLRLIGVRFSGLVRGTYQIDLFNDTEEMLALYQAM
EECCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHCEEEEEEEEEEECCHHHHHHHHHHH
DRMKNRYGFDAVMRCAGASFKPNNKNEILKRKSD
HHHHHHCCHHHHHHHCCCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA