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The map label for this gene is lytS [H]

Identifier: 146300975

GI number: 146300975

Start: 3849597

End: 3850691

Strand: Reverse

Name: lytS [H]

Synonym: Fjoh_3230

Alternate gene names: 146300975

Gene position: 3850691-3849597 (Counterclockwise)

Preceding gene: 146300976

Following gene: 146300974

Centisome position: 63.16

GC content: 33.42

Gene sequence:

>1095_bases
ATGGGTTCAAGTATTCAAAATAAAATTACAGGAAAGAATTTTTTCTACAAATACTATAGAATTATAGTAATTCCAGTGGT
TTTTTTGGTGTATTTGTCATCATACTATCTTTTAAATCCCAACCAGAATTTCGAACAAGATTCCTTAATATCATTCGACA
AGTCATTTGACATCTTTATTATTCTGGTATACTGCGGTGTATTGACAGAATTAAGCCTTTTCGTAGGACGCAGTTTAAAT
CGGTTAATACGCTGGGAACATAATCCCATTTTTAGAGCAATTGCTCAATTTATCTGCCTTATAGCCGGAAATATTCTTTT
AAACTTTATTTTTTCCCATTTGTGGAATTACTTATATCCGGGAGCCTGTTTAGAAGAAAACGAACTGCTTATTATTTGGC
AGTCCAATATCATGGCTGCAATACTATCATTGTTTATCAGCTCTGTACATACCGGAATATTTTTGCTTAACCGCTGGCGT
TTAACATCAAACGAAGCAGCCGAACTTAAAATAAAAGCTTCAGAACTTCAGGAAGCCGTAACACGTTCGCAGTTAGAATC
CTTAAAACTGCAGCTTGATCCGCATTTTATATTCAATAATTTCAGCACCTTAACAGAATTAATTCACGAAGACCAGCAGG
CAGCAGCTTCATTTTTAGAAAATATTACACGCGTTTACCGCTACATGATTTCGAACTTAGATAAAGATATTATCACAGTA
AGAGAAGAAATAGAATTTTTAAATGCTTATTTTTATTTGTTGAAGAAACGTTTAGGCGAAAAAATCCAATTAGAGTTAGA
AGTAGACAGCGACTGCCTTGATATGCATTTACCGCCTTTATCACTGCAGTTATTGGTCGAAAATGCCGTAAAACACAACA
TGGCGACTTTATCAAGTCCGTTGATTATTTCGATTTATTCTGAAGAAAAAAATATAATCGTAAAGAATAATTTACAGCCA
ACATCGGGCAAAACTTTAGTGTCTACAGGCGTAGGACGTAAGAATATTGAGTTTAGATATAAAATTTTATTCAACAAAAA
ACCTGTTTTTTCACAATCGTTAGAAAGTTTTACAGTGCGTTTACCATTAATATAG

Upstream 100 bases:

>100_bases
ATGTTATTGATGCAGGTGAAAAGCCTTTTTTAGATTTCGAAACTATGTTTCTATGTGTTTAAAATAACAAAAAATAAATT
ATCAATTCTTAAAAAAGTTA

Downstream 100 bases:

>100_bases
AGAGTATGAGAATTTTGATTATTGAAGATGAGAGTATTAATGCCAGCCGGCTCAAAAGACTGTTAGAAGAATTAGAACCC
AATTGCGAGATTCTTGATAT

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MGSSIQNKITGKNFFYKYYRIIVIPVVFLVYLSSYYLLNPNQNFEQDSLISFDKSFDIFIILVYCGVLTELSLFVGRSLN
RLIRWEHNPIFRAIAQFICLIAGNILLNFIFSHLWNYLYPGACLEENELLIIWQSNIMAAILSLFISSVHTGIFLLNRWR
LTSNEAAELKIKASELQEAVTRSQLESLKLQLDPHFIFNNFSTLTELIHEDQQAAASFLENITRVYRYMISNLDKDIITV
REEIEFLNAYFYLLKKRLGEKIQLELEVDSDCLDMHLPPLSLQLLVENAVKHNMATLSSPLIISIYSEEKNIIVKNNLQP
TSGKTLVSTGVGRKNIEFRYKILFNKKPVFSQSLESFTVRLPLI

Sequences:

>Translated_364_residues
MGSSIQNKITGKNFFYKYYRIIVIPVVFLVYLSSYYLLNPNQNFEQDSLISFDKSFDIFIILVYCGVLTELSLFVGRSLN
RLIRWEHNPIFRAIAQFICLIAGNILLNFIFSHLWNYLYPGACLEENELLIIWQSNIMAAILSLFISSVHTGIFLLNRWR
LTSNEAAELKIKASELQEAVTRSQLESLKLQLDPHFIFNNFSTLTELIHEDQQAAASFLENITRVYRYMISNLDKDIITV
REEIEFLNAYFYLLKKRLGEKIQLELEVDSDCLDMHLPPLSLQLLVENAVKHNMATLSSPLIISIYSEEKNIIVKNNLQP
TSGKTLVSTGVGRKNIEFRYKILFNKKPVFSQSLESFTVRLPLI
>Mature_363_residues
GSSIQNKITGKNFFYKYYRIIVIPVVFLVYLSSYYLLNPNQNFEQDSLISFDKSFDIFIILVYCGVLTELSLFVGRSLNR
LIRWEHNPIFRAIAQFICLIAGNILLNFIFSHLWNYLYPGACLEENELLIIWQSNIMAAILSLFISSVHTGIFLLNRWRL
TSNEAAELKIKASELQEAVTRSQLESLKLQLDPHFIFNNFSTLTELIHEDQQAAASFLENITRVYRYMISNLDKDIITVR
EEIEFLNAYFYLLKKRLGEKIQLELEVDSDCLDMHLPPLSLQLLVENAVKHNMATLSSPLIISIYSEEKNIIVKNNLQPT
SGKTLVSTGVGRKNIEFRYKILFNKKPVFSQSLESFTVRLPLI

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=203, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788723, Length=239, Percent_Identity=21.3389121338912, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42132; Mature: 42000

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSIQNKITGKNFFYKYYRIIVIPVVFLVYLSSYYLLNPNQNFEQDSLISFDKSFDIFI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHCCCCCCHHHH
ILVYCGVLTELSLFVGRSLNRLIRWEHNPIFRAIAQFICLIAGNILLNFIFSHLWNYLYP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GACLEENELLIIWQSNIMAAILSLFISSVHTGIFLLNRWRLTSNEAAELKIKASELQEAV
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHH
TRSQLESLKLQLDPHFIFNNFSTLTELIHEDQQAAASFLENITRVYRYMISNLDKDIITV
HHHHHHHHHEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
REEIEFLNAYFYLLKKRLGEKIQLELEVDSDCLDMHLPPLSLQLLVENAVKHNMATLSSP
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LIISIYSEEKNIIVKNNLQPTSGKTLVSTGVGRKNIEFRYKILFNKKPVFSQSLESFTVR
EEEEEEECCCCEEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHEEEE
LPLI
ECCC
>Mature Secondary Structure 
GSSIQNKITGKNFFYKYYRIIVIPVVFLVYLSSYYLLNPNQNFEQDSLISFDKSFDIFI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHCCCCCCHHHH
ILVYCGVLTELSLFVGRSLNRLIRWEHNPIFRAIAQFICLIAGNILLNFIFSHLWNYLYP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GACLEENELLIIWQSNIMAAILSLFISSVHTGIFLLNRWRLTSNEAAELKIKASELQEAV
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHH
TRSQLESLKLQLDPHFIFNNFSTLTELIHEDQQAAASFLENITRVYRYMISNLDKDIITV
HHHHHHHHHEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
REEIEFLNAYFYLLKKRLGEKIQLELEVDSDCLDMHLPPLSLQLLVENAVKHNMATLSSP
HHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
LIISIYSEEKNIIVKNNLQPTSGKTLVSTGVGRKNIEFRYKILFNKKPVFSQSLESFTVR
EEEEEEECCCCEEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHEEEE
LPLI
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA