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The map label for this gene is cph1 [H]

Identifier: 146300878

GI number: 146300878

Start: 3722936

End: 3724567

Strand: Reverse

Name: cph1 [H]

Synonym: Fjoh_3133

Alternate gene names: 146300878

Gene position: 3724567-3722936 (Counterclockwise)

Preceding gene: 146300879

Following gene: 146300875

Centisome position: 61.09

GC content: 36.58

Gene sequence:

>1632_bases
ATGAAGGAAATTGTAAAAATTAATCTAGACAATGAAATGGACCTCATACTGGCTCATAAACGGTCAATGAAAATTGCTGA
AATGTGCGGTATGCCGCTTTCGGCTCAGACCCGTTTTTCTACAGCTGTTTCAGAAGTGGCACGATGCTCCATTGCCAATG
GGAAAAATTCTGTGCTGGTTTTGGGAATTAATACCATTAGAGCAAGCCACAAAGAAATAATGGCTGTGCTTACAGATAAA
GTCGATCTTAAAAAATGCAATCCTGAAGCCTATAAATATGCTGCCAAAATATCAGGCAATATAGAATATAATTATGCTGA
CAACAAATCAGTAACAACTTTAAGCCATCAAGTCCCGTCACCCGGGCTTCTTTCAGATGCAAAGATCAATACTCTGGCAG
ATTATTTCAAATACGAACCGCCAATTTCTGCTTATGATGAAATCAGAAAAAAGAATATTGAGCTTGTAGCACTTTCAGAA
AAGCTGGGAGAAAGTGAAAATCGATATAGAAACTTAGTGGATACAATTCCCGTTTTAATCTGCATCGTTAATGACCGAAA
TATGGTGCTGCTGGCAAATAATGCATTTGAATTTTATCTAAAAGTTCCTTTACTTTCTTTTGATAAAAAAAGCCTGAGCG
CATTTATACATCATGACGATGTACAGCTGATTATTGAAGGATGGAGTAATGCAAAAAAAAACAGAGGAGATTTTTCTGCC
GATATTCGTATTAAAAAAGAAGACATTTATATTTGGCATAATATTTCTATTATGCCAAATAAAGCCGAAGATGGTTCTGT
AGGCAGCTGGCTTATTTATTTTGTAAATAATAATGCCCAAAAAATGATTGTTGAAGCGCTGAAGGATAATTCAGAGCTTA
GAAAAATTCAGCTTGAGCTGGAAAGTGCGAACTCAAAACTTCAATTCAAAAACAAGGAACTGGAGCAGTTTGCCTTTATA
ACAAGTCATGATCTTCAGGAACCGCTGCGAAAAATCATGATTATGATTTCAAGAGCAGCAGAACATTTGACTGAGCAGCA
GAAAACGCTTTATTATTTTGATAAAATTACGATGGCAGCCGGCAGATTATCTAATTTGATTTCAGACGTTCTTAATTACT
CCCGTGTCAATAATCATGATAAATTTACTGCAGAAGTTGATCTTAATGATATCGTTGCACAGACTTTAGAAGATTTGAGT
CTTATTATTGAAGAAAAAAAAGCCGTTGTAAATTTAAGTCCGCTTCCAGCTGTTAATGGAATAGGGACCCAGCTGCGCCA
GCTGTTTTATAATTTAATAAATAATGCATTAAAATTTAATACAGCACACCCGGCAGTAAATATATCGTACCGTCTAATTT
CAGCCCAAAGCAACACCTCTTTTGATCCTCAGGCTCCGTCAGGGAATTTTCATGTAATTTCAATTGAAGATAATGGAATT
GGAATGGACAGCGAATATTCAGGCCGCATTTTTGATATGTTCCAGCGCCTGCACCAAAGAGATCAGTACAGCGGGAATGG
TATTGGGCTGGCCTTGTGCAAACGTATTATTGAAAACCATAACGGAACCATTAATTTTACCAGTATACCAGGAAAGGGAA
CAACTTTTTGGATCTACCTGCCAAAAAATTAA

Upstream 100 bases:

>100_bases
TTAAACAGAGTCCGGCCATTATTGCCTCTGCCTTGTATATAGACAATGTGAGAGGAACTGATGATGCTACGGTTCTGGTT
GGAAAAATTATTTAAGCTTT

Downstream 100 bases:

>100_bases
AGCTTGTATTTTATAGTCTTATAGCTGTTTATCAATTTATATAAGAGATTTTAGCCAGCGATTGTATTTTTTCTATCTGC
TTTAAATGTCTTATAATATG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MKEIVKINLDNEMDLILAHKRSMKIAEMCGMPLSAQTRFSTAVSEVARCSIANGKNSVLVLGINTIRASHKEIMAVLTDK
VDLKKCNPEAYKYAAKISGNIEYNYADNKSVTTLSHQVPSPGLLSDAKINTLADYFKYEPPISAYDEIRKKNIELVALSE
KLGESENRYRNLVDTIPVLICIVNDRNMVLLANNAFEFYLKVPLLSFDKKSLSAFIHHDDVQLIIEGWSNAKKNRGDFSA
DIRIKKEDIYIWHNISIMPNKAEDGSVGSWLIYFVNNNAQKMIVEALKDNSELRKIQLELESANSKLQFKNKELEQFAFI
TSHDLQEPLRKIMIMISRAAEHLTEQQKTLYYFDKITMAAGRLSNLISDVLNYSRVNNHDKFTAEVDLNDIVAQTLEDLS
LIIEEKKAVVNLSPLPAVNGIGTQLRQLFYNLINNALKFNTAHPAVNISYRLISAQSNTSFDPQAPSGNFHVISIEDNGI
GMDSEYSGRIFDMFQRLHQRDQYSGNGIGLALCKRIIENHNGTINFTSIPGKGTTFWIYLPKN

Sequences:

>Translated_543_residues
MKEIVKINLDNEMDLILAHKRSMKIAEMCGMPLSAQTRFSTAVSEVARCSIANGKNSVLVLGINTIRASHKEIMAVLTDK
VDLKKCNPEAYKYAAKISGNIEYNYADNKSVTTLSHQVPSPGLLSDAKINTLADYFKYEPPISAYDEIRKKNIELVALSE
KLGESENRYRNLVDTIPVLICIVNDRNMVLLANNAFEFYLKVPLLSFDKKSLSAFIHHDDVQLIIEGWSNAKKNRGDFSA
DIRIKKEDIYIWHNISIMPNKAEDGSVGSWLIYFVNNNAQKMIVEALKDNSELRKIQLELESANSKLQFKNKELEQFAFI
TSHDLQEPLRKIMIMISRAAEHLTEQQKTLYYFDKITMAAGRLSNLISDVLNYSRVNNHDKFTAEVDLNDIVAQTLEDLS
LIIEEKKAVVNLSPLPAVNGIGTQLRQLFYNLINNALKFNTAHPAVNISYRLISAQSNTSFDPQAPSGNFHVISIEDNGI
GMDSEYSGRIFDMFQRLHQRDQYSGNGIGLALCKRIIENHNGTINFTSIPGKGTTFWIYLPKN
>Mature_543_residues
MKEIVKINLDNEMDLILAHKRSMKIAEMCGMPLSAQTRFSTAVSEVARCSIANGKNSVLVLGINTIRASHKEIMAVLTDK
VDLKKCNPEAYKYAAKISGNIEYNYADNKSVTTLSHQVPSPGLLSDAKINTLADYFKYEPPISAYDEIRKKNIELVALSE
KLGESENRYRNLVDTIPVLICIVNDRNMVLLANNAFEFYLKVPLLSFDKKSLSAFIHHDDVQLIIEGWSNAKKNRGDFSA
DIRIKKEDIYIWHNISIMPNKAEDGSVGSWLIYFVNNNAQKMIVEALKDNSELRKIQLELESANSKLQFKNKELEQFAFI
TSHDLQEPLRKIMIMISRAAEHLTEQQKTLYYFDKITMAAGRLSNLISDVLNYSRVNNHDKFTAEVDLNDIVAQTLEDLS
LIIEEKKAVVNLSPLPAVNGIGTQLRQLFYNLINNALKFNTAHPAVNISYRLISAQSNTSFDPQAPSGNFHVISIEDNGI
GMDSEYSGRIFDMFQRLHQRDQYSGNGIGLALCKRIIENHNGTINFTSIPGKGTTFWIYLPKN

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=263, Percent_Identity=31.1787072243346, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788713, Length=404, Percent_Identity=25.7425742574257, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI145693157, Length=399, Percent_Identity=23.3082706766917, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=27.4131274131274, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=285, Percent_Identity=24.2105263157895, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=275, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=25.5144032921811, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=281, Percent_Identity=22.0640569395018, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=233, Percent_Identity=24.8927038626609, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61339; Mature: 61339

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVKINLDNEMDLILAHKRSMKIAEMCGMPLSAQTRFSTAVSEVARCSIANGKNSVLV
CCCEEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEE
LGINTIRASHKEIMAVLTDKVDLKKCNPEAYKYAAKISGNIEYNYADNKSVTTLSHQVPS
EEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEECCEEEEECCCCCEEEEECCCCC
PGLLSDAKINTLADYFKYEPPISAYDEIRKKNIELVALSEKLGESENRYRNLVDTIPVLI
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHCEEEE
CIVNDRNMVLLANNAFEFYLKVPLLSFDKKSLSAFIHHDDVQLIIEGWSNAKKNRGDFSA
EEECCCCEEEEECCCEEEEEEECEEECCHHHHHHEEECCCEEEEEECCCCCCCCCCCCEE
DIRIKKEDIYIWHNISIMPNKAEDGSVGSWLIYFVNNNAQKMIVEALKDNSELRKIQLEL
EEEEEECEEEEEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEEEEE
ESANSKLQFKNKELEQFAFITSHDLQEPLRKIMIMISRAAEHLTEQQKTLYYFDKITMAA
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHH
GRLSNLISDVLNYSRVNNHDKFTAEVDLNDIVAQTLEDLSLIIEEKKAVVNLSPLPAVNG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCC
IGTQLRQLFYNLINNALKFNTAHPAVNISYRLISAQSNTSFDPQAPSGNFHVISIEDNGI
HHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCC
GMDSEYSGRIFDMFQRLHQRDQYSGNGIGLALCKRIIENHNGTINFTSIPGKGTTFWIYL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEE
PKN
CCC
>Mature Secondary Structure
MKEIVKINLDNEMDLILAHKRSMKIAEMCGMPLSAQTRFSTAVSEVARCSIANGKNSVLV
CCCEEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCEEE
LGINTIRASHKEIMAVLTDKVDLKKCNPEAYKYAAKISGNIEYNYADNKSVTTLSHQVPS
EEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEECCEEEEECCCCCEEEEECCCCC
PGLLSDAKINTLADYFKYEPPISAYDEIRKKNIELVALSEKLGESENRYRNLVDTIPVLI
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHCEEEE
CIVNDRNMVLLANNAFEFYLKVPLLSFDKKSLSAFIHHDDVQLIIEGWSNAKKNRGDFSA
EEECCCCEEEEECCCEEEEEEECEEECCHHHHHHEEECCCEEEEEECCCCCCCCCCCCEE
DIRIKKEDIYIWHNISIMPNKAEDGSVGSWLIYFVNNNAQKMIVEALKDNSELRKIQLEL
EEEEEECEEEEEEEEEEECCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEEEEE
ESANSKLQFKNKELEQFAFITSHDLQEPLRKIMIMISRAAEHLTEQQKTLYYFDKITMAA
ECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHH
GRLSNLISDVLNYSRVNNHDKFTAEVDLNDIVAQTLEDLSLIIEEKKAVVNLSPLPAVNG
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCC
IGTQLRQLFYNLINNALKFNTAHPAVNISYRLISAQSNTSFDPQAPSGNFHVISIEDNGI
HHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCC
GMDSEYSGRIFDMFQRLHQRDQYSGNGIGLALCKRIIENHNGTINFTSIPGKGTTFWIYL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEE
PKN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]