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The map label for this gene is evgS [H]

Identifier: 146300865

GI number: 146300865

Start: 3698566

End: 3702600

Strand: Reverse

Name: evgS [H]

Synonym: Fjoh_3120

Alternate gene names: 146300865

Gene position: 3702600-3698566 (Counterclockwise)

Preceding gene: 146300866

Following gene: 146300864

Centisome position: 60.73

GC content: 33.53

Gene sequence:

>4035_bases
ATGAGACTAAAATCCCTTTTATTATTCTTGCTTTCGGCCCTTTTTTATCATTCGTATTCACAGAATATAAAATTTGCGCA
TTATAATGATAATAACGGCTTATCTCATAATTCGGTACGACATATTGTACAGGATAAAAAAGGTTTCATGTGGTTTGGAA
CGTTTTCAGGATTAAATCGTTTTGACGGTTATCAGTTCAAAAACTACATGAGTTCTACGCCTGGAAAAAACAAATTATAC
AACGATGACATTACGGCTTTAAAACTGGACGAAAAAGCTAATCAGTTATGGATTGGAACCCGAAAAGGATTAACGCTTTT
TCAAATGGATACTCATGTTTTTACTACTTTTTTCCATAAAAAAGAAGATCCCAACAGTCTTCCGGATGATGAAGTCAGAT
CGGTTTATGTAGATAAATTCAAAAGAATCTGGGTAGGAACCAAGACCAAAGGAGTTTACTTATTCTTTTTGCAGGAAAAC
CGATTTGAAAAAATTGATCTAAAAGGTTTCGATTATGTAAAAGAAATTTTTGAAGACAAAAAAGGTAATATCTGGGTTGG
AAGTTATGAAAAAGCGGGGGTAGCCAAAATTACTTTAGACTCAAAAGGAGCAATTGTCAGAATTAATAATTATACGCTTT
CTGTTCCAAATTCGAATATAAAAAATCCATATCTGAATTTTATTTACGAAGATGCCAAATCGGATATTTTTATTGGAACC
CGTGAAGGATTGTATAAACTGGATAAAGCAAGCGATAAGTTTGTTAATCTGTATATTGACAACAAACAGGTTAGAGGTGC
TTTAGGACCTTATTTTCTTTCAGTTGCACGAGCTCCTGATGGCAAATACTGGGTTGGAACTTTAGGCGGATTATTGGTTT
GTGATCAATTAGAAGACATTCAAAATGGAAATTACAAATGGTATTATTCAATTTTATCAGATGATACTTCGCTGGTAGAT
AACCTGATTTCGGCACTTTATTTTGATGCTTCAGGCGTTTTATGGATTGGAACCGAAGACGGATTGGATAAATACGACCC
TTACGAAAATCAGTTTACTTTAAACAAAGACATATCACGTTCTATTGGTAATCAAGCTCCTAGAATTAGAGGTTTTGCCA
AAACGTATGACGAAAAAGTGATTGTTGCAACTTATCACAACGGACTTTTTATTTCGAATACAAAAGGTTCGACGCCTTTG
CACAACACAGGAAAAGACATTGCCAGCATTTATTCTGATGACGGAAAGATTTTTTACTGCGGTCTTTGGGACGGAAACAT
TTTGGTGTACAATTACGCCGCAAATTCTTCAAGGGAAATTAAAGCAGGATTCGAAAAATCGCCTGTTTTTGCTTTTTCTA
AAATTACACCCGATAAAATGATTGTAGGTTCATTTGGAGAAGGAGCTGTAATTCTCAATACTAAAACGCTTCAGGTAGAA
ACGTCAAGTAAACTTTTACCTAATTTTCAGATCAATGCGATAGAAAGAGACGCCAAAAATAACGTTTGGTTTGCTACTGA
AACCGGAGTGGTGAAATACAATATTAATTCAGGAAAAATAGAAACCTATTCGTCACTTTTTGTCAAAGAAAAAGGAGTGC
CGCATGATGAAAATGTAAGCGATGTTTTAGTAGATGTTAAAGGCAAAATCTGGGCTTCAACTCGTTTTGGTTTGTGTTTG
TTTAATCCGAAAAAAAATGAATTTGAACCTGTAAAAAATCTTAAAGAGCTTTCAGGAAAATGGATTACTGATATTCTTTC
GGATGCCAATGGAAACCTTTGGCTCAATATCAACAACAATAATATTGCTTTTGTAAAATCTAATCTAAAAGATATTAGTA
TTTACCATGTAAACAGCGGTAACAGACTGGATGTTTTTAGTTCGAGCGGTTTCTTTTATTTTAATAATTCAAATATTTTT
CTGGGAGGTAAAAACGGGATTATTTCTTTTTCGCCGCCGGCAATGAAAAGAAACAATTGGTCACCACTGCCTGTGATTTC
TGAATTTAAAATTCAGAACGAAGAAGTTTTTCCTGAAATGGAAATCAATGGGGAAATTCCGCTTTCAAAAGACCTGAATT
ATGGTAAAGAAATAGAATTAAGCCATAAAAACCGAAATTTCTCTCTTCAGTTTTCAGCTCCGTCTTTTGCAAACGAAAAA
CTGAATAAGTTTCAGTACATGCTGGAAGGTTTTGATAAACATTGGATTACGGCAAATAGTACCTCAAGAATAGTTCAATA
TACCAACCTTTATCCGGGAAATTATACTTTTAAAATCAGATCCAGCAACAGCGACGGATATTGGAGTAAAACGGTTTCTT
ATAAAATAAAAATTCTGCCTCCTTTTTGGCTTACGCCGACTTCTTTTTTAATGTTTTTTGCAATTTTATTTGGAGTCTTT
TATTTCATTAGAAAAGAAATCAAAAACCGTATACGTTTAAAACAAGAACTGCTTACCGAGAAAGTAAACAGAGAGCATGA
TATAAAATTAAACAATGAGAAATTACGTTTCTTTACCAATATTTCGCATGAATTAAGAACGCCTTTAACCTTGATTTTAG
GTCCGGCGAAACAGCTTTTAGACGAAAACAGCAACGCAACAGATTATGAAAAAAGCCGATATAATTTAATTTATCAAAAT
GCCAGCAGATTATTGAATTTGGTGAATCAGGTTTTGGATTTTAGAAAAGCACAGTCAGGCGAATTAAAGCTGAAAGTGAC
TAAAACGGATATTCTGGTGTATTCTAAAAATATCTTTGATTCCTTTAAGGAAATGGCTTATAACAAAAAGATTAAGCTCA
ATTTTATTACCGAAGATGACGAAATAAACGGCTGGCTGGACAATGATAAATACGATAAGATTTTGTACAATCTTTTGTCG
AATGCCTTAAAGTTTACCAACAAAAATGGAAACGTAGATTTATATGTTAGACTGAAAGACACAGTTGAAGATATTCTTGT
TATCGAAGTAACCGATGATGGAATTGGGATTCCGTTAAAAAGTCAGGAGAAAATTTTCAAACGTTTTTATCAGGCGACCA
ATAGTAAAGCCAATAATACTGGTTCTGGAATTGGTTTGTCTTTAGTAAAATCTTTAGTGGCAATTCATAAAGGAACTATT
TCTGTTGAAAGCACACAAGCTAAAGGAAGTACATTTAGAGTGGAAATTCCGATTGATCGTGAATCTTATGAGCATAAAGA
AGTATTTGAATATGCGCTTAAAAATGACAATCTGAGCATGCTTATTCCTGAAAAAGCGGCGAAGAAAATTATTCAAAACA
CCGATTTAAAAGAAAAAATATTAGTAATAGAAGATAATAACGAACTTAGAAAATATCTGGTGGATTATTTGTCTGATTAT
TACAAGGTTTATGAGGCAGAAAATGGTTCTGAAGGTTTAAAAATCTGCAGACAAATAAAACCTATTTTATGCGTTACCGA
TGTCATGATGCCCGTTATGGACGGATTGGAATTTTGCCGTGAGCTTAAAAATGACGAATTCATAAGTCATATTCCGGTTG
TAATGCTGACGGCCCTTTCTGAAAATATGGACAAAGTAAAAGGCTATGACACTGGAGCTGATGGCTATTTAGTTAAACCT
TTTGAGCCTTTATTACTTAAAACGGTTATAGAAAATATGATCAAATCGAGATTAGAGCTCAAACAGAAATTCTCTGGCGA
AGTAGAAAGTAAAGTCAGTATGCTGACGCACTCGCCAATTGATGAAGAATTTATGGAAAAAGTGACTAATCTAATCAATG
ATAACTTAAGTGAAGTTGATCTTTCGACAGATTTTCTGTGTGATAAATTGGGCGTAAGTTCTTCAAAATTATACAGAAAA
ATTAAAGAACTAACCGATTTAGCGCCAAACGAATTTATTAGAACCATTCGTTTAAAAAAATCAGCAGAACTGCTTAAAAC
GAAAAAATATAATGTTTCGGAAGTGACGAATCTAGTTGGTTTTAATGATCCGCTTTATTTCAGTCGCTGCTTTAAAAAGC
AGTTTGGTTTTCCTCCTAGTAAAATTATTAATTAG

Upstream 100 bases:

>100_bases
AAAATTGATTTAAAAAACAACAAAATTGATAATTTATCTGTTAAATAATTTTGATATTTATTAAATCAAAAAGATTAAAT
TGCATTTATAATTTATTTCC

Downstream 100 bases:

>100_bases
GTTTTTTAGCGACAGATTACACAGATTATAAGGATTTTTCTTTTGCCGCTAATTGCACGAATTCCCACAAATTATTCAAG
TAAATGTTTTGAAGATTATA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1344; Mature: 1344

Protein sequence:

>1344_residues
MRLKSLLLFLLSALFYHSYSQNIKFAHYNDNNGLSHNSVRHIVQDKKGFMWFGTFSGLNRFDGYQFKNYMSSTPGKNKLY
NDDITALKLDEKANQLWIGTRKGLTLFQMDTHVFTTFFHKKEDPNSLPDDEVRSVYVDKFKRIWVGTKTKGVYLFFLQEN
RFEKIDLKGFDYVKEIFEDKKGNIWVGSYEKAGVAKITLDSKGAIVRINNYTLSVPNSNIKNPYLNFIYEDAKSDIFIGT
REGLYKLDKASDKFVNLYIDNKQVRGALGPYFLSVARAPDGKYWVGTLGGLLVCDQLEDIQNGNYKWYYSILSDDTSLVD
NLISALYFDASGVLWIGTEDGLDKYDPYENQFTLNKDISRSIGNQAPRIRGFAKTYDEKVIVATYHNGLFISNTKGSTPL
HNTGKDIASIYSDDGKIFYCGLWDGNILVYNYAANSSREIKAGFEKSPVFAFSKITPDKMIVGSFGEGAVILNTKTLQVE
TSSKLLPNFQINAIERDAKNNVWFATETGVVKYNINSGKIETYSSLFVKEKGVPHDENVSDVLVDVKGKIWASTRFGLCL
FNPKKNEFEPVKNLKELSGKWITDILSDANGNLWLNINNNNIAFVKSNLKDISIYHVNSGNRLDVFSSSGFFYFNNSNIF
LGGKNGIISFSPPAMKRNNWSPLPVISEFKIQNEEVFPEMEINGEIPLSKDLNYGKEIELSHKNRNFSLQFSAPSFANEK
LNKFQYMLEGFDKHWITANSTSRIVQYTNLYPGNYTFKIRSSNSDGYWSKTVSYKIKILPPFWLTPTSFLMFFAILFGVF
YFIRKEIKNRIRLKQELLTEKVNREHDIKLNNEKLRFFTNISHELRTPLTLILGPAKQLLDENSNATDYEKSRYNLIYQN
ASRLLNLVNQVLDFRKAQSGELKLKVTKTDILVYSKNIFDSFKEMAYNKKIKLNFITEDDEINGWLDNDKYDKILYNLLS
NALKFTNKNGNVDLYVRLKDTVEDILVIEVTDDGIGIPLKSQEKIFKRFYQATNSKANNTGSGIGLSLVKSLVAIHKGTI
SVESTQAKGSTFRVEIPIDRESYEHKEVFEYALKNDNLSMLIPEKAAKKIIQNTDLKEKILVIEDNNELRKYLVDYLSDY
YKVYEAENGSEGLKICRQIKPILCVTDVMMPVMDGLEFCRELKNDEFISHIPVVMLTALSENMDKVKGYDTGADGYLVKP
FEPLLLKTVIENMIKSRLELKQKFSGEVESKVSMLTHSPIDEEFMEKVTNLINDNLSEVDLSTDFLCDKLGVSSSKLYRK
IKELTDLAPNEFIRTIRLKKSAELLKTKKYNVSEVTNLVGFNDPLYFSRCFKKQFGFPPSKIIN

Sequences:

>Translated_1344_residues
MRLKSLLLFLLSALFYHSYSQNIKFAHYNDNNGLSHNSVRHIVQDKKGFMWFGTFSGLNRFDGYQFKNYMSSTPGKNKLY
NDDITALKLDEKANQLWIGTRKGLTLFQMDTHVFTTFFHKKEDPNSLPDDEVRSVYVDKFKRIWVGTKTKGVYLFFLQEN
RFEKIDLKGFDYVKEIFEDKKGNIWVGSYEKAGVAKITLDSKGAIVRINNYTLSVPNSNIKNPYLNFIYEDAKSDIFIGT
REGLYKLDKASDKFVNLYIDNKQVRGALGPYFLSVARAPDGKYWVGTLGGLLVCDQLEDIQNGNYKWYYSILSDDTSLVD
NLISALYFDASGVLWIGTEDGLDKYDPYENQFTLNKDISRSIGNQAPRIRGFAKTYDEKVIVATYHNGLFISNTKGSTPL
HNTGKDIASIYSDDGKIFYCGLWDGNILVYNYAANSSREIKAGFEKSPVFAFSKITPDKMIVGSFGEGAVILNTKTLQVE
TSSKLLPNFQINAIERDAKNNVWFATETGVVKYNINSGKIETYSSLFVKEKGVPHDENVSDVLVDVKGKIWASTRFGLCL
FNPKKNEFEPVKNLKELSGKWITDILSDANGNLWLNINNNNIAFVKSNLKDISIYHVNSGNRLDVFSSSGFFYFNNSNIF
LGGKNGIISFSPPAMKRNNWSPLPVISEFKIQNEEVFPEMEINGEIPLSKDLNYGKEIELSHKNRNFSLQFSAPSFANEK
LNKFQYMLEGFDKHWITANSTSRIVQYTNLYPGNYTFKIRSSNSDGYWSKTVSYKIKILPPFWLTPTSFLMFFAILFGVF
YFIRKEIKNRIRLKQELLTEKVNREHDIKLNNEKLRFFTNISHELRTPLTLILGPAKQLLDENSNATDYEKSRYNLIYQN
ASRLLNLVNQVLDFRKAQSGELKLKVTKTDILVYSKNIFDSFKEMAYNKKIKLNFITEDDEINGWLDNDKYDKILYNLLS
NALKFTNKNGNVDLYVRLKDTVEDILVIEVTDDGIGIPLKSQEKIFKRFYQATNSKANNTGSGIGLSLVKSLVAIHKGTI
SVESTQAKGSTFRVEIPIDRESYEHKEVFEYALKNDNLSMLIPEKAAKKIIQNTDLKEKILVIEDNNELRKYLVDYLSDY
YKVYEAENGSEGLKICRQIKPILCVTDVMMPVMDGLEFCRELKNDEFISHIPVVMLTALSENMDKVKGYDTGADGYLVKP
FEPLLLKTVIENMIKSRLELKQKFSGEVESKVSMLTHSPIDEEFMEKVTNLINDNLSEVDLSTDFLCDKLGVSSSKLYRK
IKELTDLAPNEFIRTIRLKKSAELLKTKKYNVSEVTNLVGFNDPLYFSRCFKKQFGFPPSKIIN
>Mature_1344_residues
MRLKSLLLFLLSALFYHSYSQNIKFAHYNDNNGLSHNSVRHIVQDKKGFMWFGTFSGLNRFDGYQFKNYMSSTPGKNKLY
NDDITALKLDEKANQLWIGTRKGLTLFQMDTHVFTTFFHKKEDPNSLPDDEVRSVYVDKFKRIWVGTKTKGVYLFFLQEN
RFEKIDLKGFDYVKEIFEDKKGNIWVGSYEKAGVAKITLDSKGAIVRINNYTLSVPNSNIKNPYLNFIYEDAKSDIFIGT
REGLYKLDKASDKFVNLYIDNKQVRGALGPYFLSVARAPDGKYWVGTLGGLLVCDQLEDIQNGNYKWYYSILSDDTSLVD
NLISALYFDASGVLWIGTEDGLDKYDPYENQFTLNKDISRSIGNQAPRIRGFAKTYDEKVIVATYHNGLFISNTKGSTPL
HNTGKDIASIYSDDGKIFYCGLWDGNILVYNYAANSSREIKAGFEKSPVFAFSKITPDKMIVGSFGEGAVILNTKTLQVE
TSSKLLPNFQINAIERDAKNNVWFATETGVVKYNINSGKIETYSSLFVKEKGVPHDENVSDVLVDVKGKIWASTRFGLCL
FNPKKNEFEPVKNLKELSGKWITDILSDANGNLWLNINNNNIAFVKSNLKDISIYHVNSGNRLDVFSSSGFFYFNNSNIF
LGGKNGIISFSPPAMKRNNWSPLPVISEFKIQNEEVFPEMEINGEIPLSKDLNYGKEIELSHKNRNFSLQFSAPSFANEK
LNKFQYMLEGFDKHWITANSTSRIVQYTNLYPGNYTFKIRSSNSDGYWSKTVSYKIKILPPFWLTPTSFLMFFAILFGVF
YFIRKEIKNRIRLKQELLTEKVNREHDIKLNNEKLRFFTNISHELRTPLTLILGPAKQLLDENSNATDYEKSRYNLIYQN
ASRLLNLVNQVLDFRKAQSGELKLKVTKTDILVYSKNIFDSFKEMAYNKKIKLNFITEDDEINGWLDNDKYDKILYNLLS
NALKFTNKNGNVDLYVRLKDTVEDILVIEVTDDGIGIPLKSQEKIFKRFYQATNSKANNTGSGIGLSLVKSLVAIHKGTI
SVESTQAKGSTFRVEIPIDRESYEHKEVFEYALKNDNLSMLIPEKAAKKIIQNTDLKEKILVIEDNNELRKYLVDYLSDY
YKVYEAENGSEGLKICRQIKPILCVTDVMMPVMDGLEFCRELKNDEFISHIPVVMLTALSENMDKVKGYDTGADGYLVKP
FEPLLLKTVIENMIKSRLELKQKFSGEVESKVSMLTHSPIDEEFMEKVTNLINDNLSEVDLSTDFLCDKLGVSSSKLYRK
IKELTDLAPNEFIRTIRLKKSAELLKTKKYNVSEVTNLVGFNDPLYFSRCFKKQFGFPPSKIIN

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=397, Percent_Identity=30.9823677581864, Blast_Score=150, Evalue=5e-37,
Organism=Escherichia coli, GI48994928, Length=436, Percent_Identity=29.5871559633028, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=31.1111111111111, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=33.0434782608696, Blast_Score=109, Evalue=1e-24,
Organism=Escherichia coli, GI87081816, Length=368, Percent_Identity=25.2717391304348, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.2792792792793, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=27.0742358078603, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=25.3218884120172, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=27.5303643724696, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=26.8199233716475, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1788394, Length=129, Percent_Identity=35.6589147286822, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.0334728033473, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786911, Length=103, Percent_Identity=40.7766990291262, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=34.7107438016529, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=26.4069264069264, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=25.7009345794392, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1788279, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=24.3362831858407, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI87082012, Length=125, Percent_Identity=34.4, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=24.2553191489362, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 153958; Mature: 153958

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKSLLLFLLSALFYHSYSQNIKFAHYNDNNGLSHNSVRHIVQDKKGFMWFGTFSGLNR
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
FDGYQFKNYMSSTPGKNKLYNDDITALKLDEKANQLWIGTRKGLTLFQMDTHVFTTFFHK
CCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEEEEEECHHHHHHHHHC
KEDPNSLPDDEVRSVYVDKFKRIWVGTKTKGVYLFFLQENRFEKIDLKGFDYVKEIFEDK
CCCCCCCCCHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEECCCCHHHHHHHHHCC
KGNIWVGSYEKAGVAKITLDSKGAIVRINNYTLSVPNSNIKNPYLNFIYEDAKSDIFIGT
CCCEEEECCCCCCEEEEEECCCCCEEEEECEEEECCCCCCCCCHHHHEEECCCCCEEEEC
REGLYKLDKASDKFVNLYIDNKQVRGALGPYFLSVARAPDGKYWVGTLGGLLVCDQLEDI
CCCHHHHCCCCCEEEEEEEECCHHCCCCCHHHHEEEECCCCCEEHCCCCCCEEEHHHHHH
QNGNYKWYYSILSDDTSLVDNLISALYFDASGVLWIGTEDGLDKYDPYENQFTLNKDISR
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCHHHH
SIGNQAPRIRGFAKTYDEKVIVATYHNGLFISNTKGSTPLHNTGKDIASIYSDDGKIFYC
HHCCCCCCHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEE
GLWDGNILVYNYAANSSREIKAGFEKSPVFAFSKITPDKMIVGSFGEGAVILNTKTLQVE
EEECCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEEEEEEEEEEE
TSSKLLPNFQINAIERDAKNNVWFATETGVVKYNINSGKIETYSSLFVKEKGVPHDENVS
CCCCCCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCEEHHHHHHEECCCCCCCCCHH
DVLVDVKGKIWASTRFGLCLFNPKKNEFEPVKNLKELSGKWITDILSDANGNLWLNINNN
HEEEECCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCC
NIAFVKSNLKDISIYHVNSGNRLDVFSSSGFFYFNNSNIFLGGKNGIISFSPPAMKRNNW
EEEEEECCCCEEEEEEECCCCEEEEEECCCEEEECCCEEEEECCCCEEEECCCCCCCCCC
SPLPVISEFKIQNEEVFPEMEINGEIPLSKDLNYGKEIELSHKNRNFSLQFSAPSFANEK
CCCCCHHHEEECCCCCCCCEECCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHH
LNKFQYMLEGFDKHWITANSTSRIVQYTNLYPGNYTFKIRSSNSDGYWSKTVSYKIKILP
HHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEEC
PFWLTPTSFLMFFAILFGVFYFIRKEIKNRIRLKQELLTEKVNREHDIKLNNEKLRFFTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEC
ISHELRTPLTLILGPAKQLLDENSNATDYEKSRYNLIYQNASRLLNLVNQVLDFRKAQSG
CCHHHCCCEEEEECCHHHHHCCCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHCCCCC
ELKLKVTKTDILVYSKNIFDSFKEMAYNKKIKLNFITEDDEINGWLDNDKYDKILYNLLS
CEEEEEEEEEEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
NALKFTNKNGNVDLYVRLKDTVEDILVIEVTDDGIGIPLKSQEKIFKRFYQATNSKANNT
HHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GSGIGLSLVKSLVAIHKGTISVESTQAKGSTFRVEIPIDRESYEHKEVFEYALKNDNLSM
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEE
LIPEKAAKKIIQNTDLKEKILVIEDNNELRKYLVDYLSDYYKVYEAENGSEGLKICRQIK
EECHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCC
PILCVTDVMMPVMDGLEFCRELKNDEFISHIPVVMLTALSENMDKVKGYDTGADGYLVKP
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
FEPLLLKTVIENMIKSRLELKQKFSGEVESKVSMLTHSPIDEEFMEKVTNLINDNLSEVD
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCC
LSTDFLCDKLGVSSSKLYRKIKELTDLAPNEFIRTIRLKKSAELLKTKKYNVSEVTNLVG
CCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
FNDPLYFSRCFKKQFGFPPSKIIN
CCCCHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MRLKSLLLFLLSALFYHSYSQNIKFAHYNDNNGLSHNSVRHIVQDKKGFMWFGTFSGLNR
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
FDGYQFKNYMSSTPGKNKLYNDDITALKLDEKANQLWIGTRKGLTLFQMDTHVFTTFFHK
CCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEEEEEECHHHHHHHHHC
KEDPNSLPDDEVRSVYVDKFKRIWVGTKTKGVYLFFLQENRFEKIDLKGFDYVKEIFEDK
CCCCCCCCCHHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEECCCCHHHHHHHHHCC
KGNIWVGSYEKAGVAKITLDSKGAIVRINNYTLSVPNSNIKNPYLNFIYEDAKSDIFIGT
CCCEEEECCCCCCEEEEEECCCCCEEEEECEEEECCCCCCCCCHHHHEEECCCCCEEEEC
REGLYKLDKASDKFVNLYIDNKQVRGALGPYFLSVARAPDGKYWVGTLGGLLVCDQLEDI
CCCHHHHCCCCCEEEEEEEECCHHCCCCCHHHHEEEECCCCCEEHCCCCCCEEEHHHHHH
QNGNYKWYYSILSDDTSLVDNLISALYFDASGVLWIGTEDGLDKYDPYENQFTLNKDISR
CCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEECCHHHH
SIGNQAPRIRGFAKTYDEKVIVATYHNGLFISNTKGSTPLHNTGKDIASIYSDDGKIFYC
HHCCCCCCHHHHHHHCCCEEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEE
GLWDGNILVYNYAANSSREIKAGFEKSPVFAFSKITPDKMIVGSFGEGAVILNTKTLQVE
EEECCCEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCCCCEEEEEEEEEEEE
TSSKLLPNFQINAIERDAKNNVWFATETGVVKYNINSGKIETYSSLFVKEKGVPHDENVS
CCCCCCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCEEHHHHHHEECCCCCCCCCHH
DVLVDVKGKIWASTRFGLCLFNPKKNEFEPVKNLKELSGKWITDILSDANGNLWLNINNN
HEEEECCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCC
NIAFVKSNLKDISIYHVNSGNRLDVFSSSGFFYFNNSNIFLGGKNGIISFSPPAMKRNNW
EEEEEECCCCEEEEEEECCCCEEEEEECCCEEEECCCEEEEECCCCEEEECCCCCCCCCC
SPLPVISEFKIQNEEVFPEMEINGEIPLSKDLNYGKEIELSHKNRNFSLQFSAPSFANEK
CCCCCHHHEEECCCCCCCCEECCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHH
LNKFQYMLEGFDKHWITANSTSRIVQYTNLYPGNYTFKIRSSNSDGYWSKTVSYKIKILP
HHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEEC
PFWLTPTSFLMFFAILFGVFYFIRKEIKNRIRLKQELLTEKVNREHDIKLNNEKLRFFTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEC
ISHELRTPLTLILGPAKQLLDENSNATDYEKSRYNLIYQNASRLLNLVNQVLDFRKAQSG
CCHHHCCCEEEEECCHHHHHCCCCCCCCCCHHHHHEEHHHHHHHHHHHHHHHHHHCCCCC
ELKLKVTKTDILVYSKNIFDSFKEMAYNKKIKLNFITEDDEINGWLDNDKYDKILYNLLS
CEEEEEEEEEEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
NALKFTNKNGNVDLYVRLKDTVEDILVIEVTDDGIGIPLKSQEKIFKRFYQATNSKANNT
HHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
GSGIGLSLVKSLVAIHKGTISVESTQAKGSTFRVEIPIDRESYEHKEVFEYALKNDNLSM
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEE
LIPEKAAKKIIQNTDLKEKILVIEDNNELRKYLVDYLSDYYKVYEAENGSEGLKICRQIK
EECHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCC
PILCVTDVMMPVMDGLEFCRELKNDEFISHIPVVMLTALSENMDKVKGYDTGADGYLVKP
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
FEPLLLKTVIENMIKSRLELKQKFSGEVESKVSMLTHSPIDEEFMEKVTNLINDNLSEVD
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHCC
LSTDFLCDKLGVSSSKLYRKIKELTDLAPNEFIRTIRLKKSAELLKTKKYNVSEVTNLVG
CCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
FNDPLYFSRCFKKQFGFPPSKIIN
CCCCHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]