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The map label for this gene is yedV [H]

Identifier: 146300798

GI number: 146300798

Start: 3614023

End: 3615297

Strand: Direct

Name: yedV [H]

Synonym: Fjoh_3050

Alternate gene names: 146300798

Gene position: 3614023-3615297 (Clockwise)

Preceding gene: 146300797

Following gene: 146300799

Centisome position: 59.28

GC content: 50.98

Gene sequence:

>1275_bases
ATGGGAAAAATGAATCGTAAAAAACTGCTCAGCAAAACCACGCGCGATTTTCTCGTGCTTGCCGCCGTCATCCTTCTAAT
CTGCGCTCCGATCTTCTACTTTGTCAGCCAGTGGCTTTTCATCTACGAAACCGAGGAGGTCCTCGTGCAGCATAAAAACG
CATTCATTAACCAGTCCAGCCGCAATTTCACTCCCGAAGACATCAAGACCTGGAACAGGTACAACCTGCATTTCACCATT
ATGCCCGATATGGGCGTCACCAGGGATTCCATTGTGGGCACCGTGATCGAAGACTCGACAGCGGAAGAGAAGGAGCCGTT
CCGCATCATATACGCCCCTGTGGAAATTGCCGGCAAAAAATACACCTATACCGAAAAGATCCACCTGCTGGAAATGGAAA
GGATGGTTTTCACCATCGCAGGCATGTTCACCTTTATCCTTCTGGTGCTTTTCATCGGCATTGTATGGCTCTCCAAAAAG
ACGGCCTCCAAACGGTGGAAGCCCTTCTATGACACCCTGGACCAGATCCATGAATTTGAGATCGACAAGAACAAGCCCCC
CCATTTCCTGGAGACTGACATCGACGAATTTGAACGCCTGAACAGAAGCCTTGAGGCACTGATCGAAAAAAATACGGCCA
TCTATAAAAGCCAGCGGGAGTTTGTCGAAAATGCGGCCCATGAGCTTCAGACCCCCCTGGCACTGTTCCAGAACAAGATC
GACACCCTTTTCCAGATGAGGCTCGACAAGGACCAGACACGCGTGCTGGGAGCCTTGAGCAGGGATGTGGCAAAGCTCAA
CAGGCTCAACAAAAATCTGCTGCTGCTATCCAAAATAGAGCATGAGATCTATCTGGAAAAAACCTGCATCTCGGTCAATG
GGCATATAGAAAAGCATCTGGACTTCTTTACCGAGCAGGCCGGCCAGAAATGGGTCGCCATCAATGTGCAGCTGTCCCAA
AGGCTCGAAATAGAAGCCAACCCGGTCCTTGCCGAAATCCTGATCAACAACCTGGTGCTTAACGCCATCCGCCATAACCG
CACCGAGGGAAATATCATAATCAGGACGCTGGACCGCGAGCTGATGGTCCTCAACACCGGAAAGGCCGAACCGCTTCCCA
TTGAGAAGCTCTTCGGGCGCTTTTTCAGCGGCGGCGCCTCGGCAAACGGCAGCGGGCTGGGTCTGGCCATCATCAGGAAG
ATAACCGAGATAAGCGGCTGGAAGATCTCCTACTCCTATTATAACGATTTCCACTGCTTCAGCGTAAAATTCTAG

Upstream 100 bases:

>100_bases
GCCATGACTTCATATATGCGCACATCAAAAACCTCAAAAAGAAACTCGCCAAAGCCGGATCGGGCGACTACATTAAAACC
GTTTACGGCGAAGGATACAA

Downstream 100 bases:

>100_bases
CGGCGGCACCTGATTGCGCAGGCAGTTTCCGCTCGGATGCGTCATAGGAGAACGGCAGGCCGCAATGCGCTTTTTTTTCA
TAAACAGGGCTATTATTTCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MGKMNRKKLLSKTTRDFLVLAAVILLICAPIFYFVSQWLFIYETEEVLVQHKNAFINQSSRNFTPEDIKTWNRYNLHFTI
MPDMGVTRDSIVGTVIEDSTAEEKEPFRIIYAPVEIAGKKYTYTEKIHLLEMERMVFTIAGMFTFILLVLFIGIVWLSKK
TASKRWKPFYDTLDQIHEFEIDKNKPPHFLETDIDEFERLNRSLEALIEKNTAIYKSQREFVENAAHELQTPLALFQNKI
DTLFQMRLDKDQTRVLGALSRDVAKLNRLNKNLLLLSKIEHEIYLEKTCISVNGHIEKHLDFFTEQAGQKWVAINVQLSQ
RLEIEANPVLAEILINNLVLNAIRHNRTEGNIIIRTLDRELMVLNTGKAEPLPIEKLFGRFFSGGASANGSGLGLAIIRK
ITEISGWKISYSYYNDFHCFSVKF

Sequences:

>Translated_424_residues
MGKMNRKKLLSKTTRDFLVLAAVILLICAPIFYFVSQWLFIYETEEVLVQHKNAFINQSSRNFTPEDIKTWNRYNLHFTI
MPDMGVTRDSIVGTVIEDSTAEEKEPFRIIYAPVEIAGKKYTYTEKIHLLEMERMVFTIAGMFTFILLVLFIGIVWLSKK
TASKRWKPFYDTLDQIHEFEIDKNKPPHFLETDIDEFERLNRSLEALIEKNTAIYKSQREFVENAAHELQTPLALFQNKI
DTLFQMRLDKDQTRVLGALSRDVAKLNRLNKNLLLLSKIEHEIYLEKTCISVNGHIEKHLDFFTEQAGQKWVAINVQLSQ
RLEIEANPVLAEILINNLVLNAIRHNRTEGNIIIRTLDRELMVLNTGKAEPLPIEKLFGRFFSGGASANGSGLGLAIIRK
ITEISGWKISYSYYNDFHCFSVKF
>Mature_423_residues
GKMNRKKLLSKTTRDFLVLAAVILLICAPIFYFVSQWLFIYETEEVLVQHKNAFINQSSRNFTPEDIKTWNRYNLHFTIM
PDMGVTRDSIVGTVIEDSTAEEKEPFRIIYAPVEIAGKKYTYTEKIHLLEMERMVFTIAGMFTFILLVLFIGIVWLSKKT
ASKRWKPFYDTLDQIHEFEIDKNKPPHFLETDIDEFERLNRSLEALIEKNTAIYKSQREFVENAAHELQTPLALFQNKID
TLFQMRLDKDQTRVLGALSRDVAKLNRLNKNLLLLSKIEHEIYLEKTCISVNGHIEKHLDFFTEQAGQKWVAINVQLSQR
LEIEANPVLAEILINNLVLNAIRHNRTEGNIIIRTLDRELMVLNTGKAEPLPIEKLFGRFFSGGASANGSGLGLAIIRKI
TEISGWKISYSYYNDFHCFSVKF

Specific function: Probable member of a two-component regulatory system yedW/yedV. May activate yedW by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788279, Length=236, Percent_Identity=27.9661016949153, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=272, Percent_Identity=24.2647058823529, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=283, Percent_Identity=25.0883392226148, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789403, Length=327, Percent_Identity=23.2415902140673, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.530612244898, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49149; Mature: 49017

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMNRKKLLSKTTRDFLVLAAVILLICAPIFYFVSQWLFIYETEEVLVQHKNAFINQSS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCCCC
RNFTPEDIKTWNRYNLHFTIMPDMGVTRDSIVGTVIEDSTAEEKEPFRIIYAPVEIAGKK
CCCCHHHHHCCCEEEEEEEEECCCCCCHHHHHEEEECCCCCCCCCCEEEEEEEHHHCCCE
YTYTEKIHLLEMERMVFTIAGMFTFILLVLFIGIVWLSKKTASKRWKPFYDTLDQIHEFE
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCC
IDKNKPPHFLETDIDEFERLNRSLEALIEKNTAIYKSQREFVENAAHELQTPLALFQNKI
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLFQMRLDKDQTRVLGALSRDVAKLNRLNKNLLLLSKIEHEIYLEKTCISVNGHIEKHL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHEEEHEEEEECCCHHHHH
DFFTEQAGQKWVAINVQLSQRLEIEANPVLAEILINNLVLNAIRHNRTEGNIIIRTLDRE
HHHHHHCCCEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCE
LMVLNTGKAEPLPIEKLFGRFFSGGASANGSGLGLAIIRKITEISGWKISYSYYNDFHCF
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCEEEE
SVKF
EEEC
>Mature Secondary Structure 
GKMNRKKLLSKTTRDFLVLAAVILLICAPIFYFVSQWLFIYETEEVLVQHKNAFINQSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCCCC
RNFTPEDIKTWNRYNLHFTIMPDMGVTRDSIVGTVIEDSTAEEKEPFRIIYAPVEIAGKK
CCCCHHHHHCCCEEEEEEEEECCCCCCHHHHHEEEECCCCCCCCCCEEEEEEEHHHCCCE
YTYTEKIHLLEMERMVFTIAGMFTFILLVLFIGIVWLSKKTASKRWKPFYDTLDQIHEFE
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCC
IDKNKPPHFLETDIDEFERLNRSLEALIEKNTAIYKSQREFVENAAHELQTPLALFQNKI
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTLFQMRLDKDQTRVLGALSRDVAKLNRLNKNLLLLSKIEHEIYLEKTCISVNGHIEKHL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHEEEHEEEEECCCHHHHH
DFFTEQAGQKWVAINVQLSQRLEIEANPVLAEILINNLVLNAIRHNRTEGNIIIRTLDRE
HHHHHHCCCEEEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCE
LMVLNTGKAEPLPIEKLFGRFFSGGASANGSGLGLAIIRKITEISGWKISYSYYNDFHCF
EEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCEEEE
SVKF
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]