Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 146300797

GI number: 146300797

Start: 3613361

End: 3614035

Strand: Direct

Name: ctrA [H]

Synonym: Fjoh_3049

Alternate gene names: 146300797

Gene position: 3613361-3614035 (Clockwise)

Preceding gene: 146300796

Following gene: 146300798

Centisome position: 59.27

GC content: 49.93

Gene sequence:

>675_bases
ATGAAAATTTTAATCATAGAAGACGAACAGGATATCGCTCAAAGCATACAGAGCTATTTCAAGGACAACGGCGTAAAATG
CGAAACGGCGCACAATTATGTGCAGGCCATCCATAAGATCGACAATTATGACTACGACTGCATACTTCTTGATCTTGGCC
TTCCCGACGGGGACGGTTTTGACATCCTCAGGGAGCTGCGAAGCAAAGACAAGACCGACGGGGTGATAATCATTTCGGCA
AAAGAGACCCTGGAAACAAGGCTGGAAAGCTTCAGCCTTGGCGCCGACGACTACCTCACCAAACCCTTCCACCTTGCCGA
ACTGCTGGTAAGGATGCAGGCGCTGGTGCGCCGCAGGAACTTCAAGGGTAGCAACAGCGTGGTGTTCCAGGAGATCAGGA
TTGAAGTGTTCACCAAAACCGTGCTGGTCAATGGCCAAAAGCTCGAACTGACCAGAAAGGAGCTCAACCTTCTGCTGTTC
CTGATCGGCAACAATGACAAGGTCCTCTCAAAGGCAGCCATCGCCGAGCACCTATCGGGCGACATGGCCGATATGCTCGA
CAGCCATGACTTCATATATGCGCACATCAAAAACCTCAAAAAGAAACTCGCCAAAGCCGGATCGGGCGACTACATTAAAA
CCGTTTACGGCGAAGGATACAAATGGGAAAAATGA

Upstream 100 bases:

>100_bases
CCGTTTAAAAAAAAATGATGCCCCGCAGCGCACATATTGCCATAAATTCTTAAATTTAGTGGGCATATGCACTGTCATGG
GGCGGTAAGAAAATGGCATC

Downstream 100 bases:

>100_bases
ATCGTAAAAAACTGCTCAGCAAAACCACGCGCGATTTTCTCGTGCTTGCCGCCGTCATCCTTCTAATCTGCGCTCCGATC
TTCTACTTTGTCAGCCAGTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKILIIEDEQDIAQSIQSYFKDNGVKCETAHNYVQAIHKIDNYDYDCILLDLGLPDGDGFDILRELRSKDKTDGVIIISA
KETLETRLESFSLGADDYLTKPFHLAELLVRMQALVRRRNFKGSNSVVFQEIRIEVFTKTVLVNGQKLELTRKELNLLLF
LIGNNDKVLSKAAIAEHLSGDMADMLDSHDFIYAHIKNLKKKLAKAGSGDYIKTVYGEGYKWEK

Sequences:

>Translated_224_residues
MKILIIEDEQDIAQSIQSYFKDNGVKCETAHNYVQAIHKIDNYDYDCILLDLGLPDGDGFDILRELRSKDKTDGVIIISA
KETLETRLESFSLGADDYLTKPFHLAELLVRMQALVRRRNFKGSNSVVFQEIRIEVFTKTVLVNGQKLELTRKELNLLLF
LIGNNDKVLSKAAIAEHLSGDMADMLDSHDFIYAHIKNLKKKLAKAGSGDYIKTVYGEGYKWEK
>Mature_224_residues
MKILIIEDEQDIAQSIQSYFKDNGVKCETAHNYVQAIHKIDNYDYDCILLDLGLPDGDGFDILRELRSKDKTDGVIIISA
KETLETRLESFSLGADDYLTKPFHLAELLVRMQALVRRRNFKGSNSVVFQEIRIEVFTKTVLVNGQKLELTRKELNLLLF
LIGNNDKVLSKAAIAEHLSGDMADMLDSHDFIYAHIKNLKKKLAKAGSGDYIKTVYGEGYKWEK

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=35.9090909090909, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.2869955156951, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.0877192982456, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.6666666666667, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=29.4642857142857, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=28.2511210762332, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=30.8695652173913, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.6666666666667, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=29.0909090909091, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=26.8722466960352, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=29.3859649122807, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=25.1082251082251, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=32.2314049586777, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25505; Mature: 25505

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIIEDEQDIAQSIQSYFKDNGVKCETAHNYVQAIHKIDNYDYDCILLDLGLPDGDGF
CEEEEEECHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
DILRELRSKDKTDGVIIISAKETLETRLESFSLGADDYLTKPFHLAELLVRMQALVRRRN
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHC
FKGSNSVVFQEIRIEVFTKTVLVNGQKLELTRKELNLLLFLIGNNDKVLSKAAIAEHLSG
CCCCCCEEHHHHHHHHHHHHHEECCCEEEEEHHCEEEEEEEECCCCHHHHHHHHHHHHCC
DMADMLDSHDFIYAHIKNLKKKLAKAGSGDYIKTVYGEGYKWEK
CHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKILIIEDEQDIAQSIQSYFKDNGVKCETAHNYVQAIHKIDNYDYDCILLDLGLPDGDGF
CEEEEEECHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCH
DILRELRSKDKTDGVIIISAKETLETRLESFSLGADDYLTKPFHLAELLVRMQALVRRRN
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHC
FKGSNSVVFQEIRIEVFTKTVLVNGQKLELTRKELNLLLFLIGNNDKVLSKAAIAEHLSG
CCCCCCEEHHHHHHHHHHHHHEECCCEEEEEHHCEEEEEEEECCCCHHHHHHHHHHHHCC
DMADMLDSHDFIYAHIKNLKKKLAKAGSGDYIKTVYGEGYKWEK
CHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]