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The map label for this gene is narP [H]

Identifier: 146300722

GI number: 146300722

Start: 3523912

End: 3524562

Strand: Direct

Name: narP [H]

Synonym: Fjoh_2973

Alternate gene names: 146300722

Gene position: 3523912-3524562 (Clockwise)

Preceding gene: 146300721

Following gene: 146300725

Centisome position: 57.8

GC content: 31.8

Gene sequence:

>651_bases
ATGAAACCGAATACTAAAAGTAAAATTATTATAGTCGACGATCATCAGCTTTTTTCCCAGTCATTAGAACTTTTAATTAA
AAGCTTTGGAGATTACGAAGTTATCGACCGATTTGAGAATGGAAAAGTCTTTATTTCCTATCTGCAGGAAAACCCGGAAA
CCAATATAGATTTAGTTTTGCTTGATGTAAATATGCCTGTTTTAGATGGCTTAAGCACTATGAAATGGATTAAGGAAAAC
AGACCTGATTTAAAAGTAATTGCTCTTTCTGTAAATGACGATGAGGAAATAATCATAAAAATGATTACAAATGGCGCAAA
AGGTTATCTGCTGAAAGATACGTCACCAGATATTTTTAAAGATGCTATTGAATGTGTTATAGAAAAAGGATTTTATTACA
CCGAACTGGTTTCGGGAATTCTTATTAACAAGGTCAACAGTGATAATAAAAAAGTGAATTTAAAAGAAAAAGAACTGGTT
TTTATAAAACATGCCTGCACCGAGATGACTTACAAAGAAATCGCTTCAGAAATGTGCCTGAGTCCTAAAACCATCGACGG
TTACAGGGAATGTTTATTTGATAAATTAGAAATAAAAACCAGAATAGGTTTAGTACTGTATGCCGTTAAACACAAAATTG
TATTTGTATAA

Upstream 100 bases:

>100_bases
ACATGAAACTGAGAGCTAAACTTATTGGCGCTCAATTAATCATGGAATCAAAATGCATCAGGAACAACCGTAACCTTAGA
ATACCCTTTAACAACAACCA

Downstream 100 bases:

>100_bases
TTAATAAGTCAGCGCAGCAAAAACAGGATATTCTTTAATTTTTTTACGTCCGTTTAGAAAAGTTAACTCCATCAGGAAAT
TACATTGTACAATTTCTCCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKPNTKSKIIIVDDHQLFSQSLELLIKSFGDYEVIDRFENGKVFISYLQENPETNIDLVLLDVNMPVLDGLSTMKWIKEN
RPDLKVIALSVNDDEEIIIKMITNGAKGYLLKDTSPDIFKDAIECVIEKGFYYTELVSGILINKVNSDNKKVNLKEKELV
FIKHACTEMTYKEIASEMCLSPKTIDGYRECLFDKLEIKTRIGLVLYAVKHKIVFV

Sequences:

>Translated_216_residues
MKPNTKSKIIIVDDHQLFSQSLELLIKSFGDYEVIDRFENGKVFISYLQENPETNIDLVLLDVNMPVLDGLSTMKWIKEN
RPDLKVIALSVNDDEEIIIKMITNGAKGYLLKDTSPDIFKDAIECVIEKGFYYTELVSGILINKVNSDNKKVNLKEKELV
FIKHACTEMTYKEIASEMCLSPKTIDGYRECLFDKLEIKTRIGLVLYAVKHKIVFV
>Mature_216_residues
MKPNTKSKIIIVDDHQLFSQSLELLIKSFGDYEVIDRFENGKVFISYLQENPETNIDLVLLDVNMPVLDGLSTMKWIKEN
RPDLKVIALSVNDDEEIIIKMITNGAKGYLLKDTSPDIFKDAIECVIEKGFYYTELVSGILINKVNSDNKKVNLKEKELV
FIKHACTEMTYKEIASEMCLSPKTIDGYRECLFDKLEIKTRIGLVLYAVKHKIVFV

Specific function: Could activate the expression of a formate dehydrogenase operon and could repress the transcription of the fumarate reductase (frdABCD) operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=25.8373205741627, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786747, Length=211, Percent_Identity=27.0142180094787, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788521, Length=216, Percent_Identity=26.8518518518519, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790102, Length=191, Percent_Identity=26.7015706806283, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787473, Length=190, Percent_Identity=25.2631578947368, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=24.8780487804878, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24776; Mature: 24776

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNTKSKIIIVDDHQLFSQSLELLIKSFGDYEVIDRFENGKVFISYLQENPETNIDLVL
CCCCCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCEEEEE
LDVNMPVLDGLSTMKWIKENRPDLKVIALSVNDDEEIIIKMITNGAKGYLLKDTSPDIFK
EECCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHEEEEEECCCCCCEEEECCCCHHHH
DAIECVIEKGFYYTELVSGILINKVNSDNKKVNLKEKELVFIKHACTEMTYKEIASEMCL
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCHHHEEEEHHHHHHHHHHHHHHHHHC
SPKTIDGYRECLFDKLEIKTRIGLVLYAVKHKIVFV
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEHEEEEEC
>Mature Secondary Structure
MKPNTKSKIIIVDDHQLFSQSLELLIKSFGDYEVIDRFENGKVFISYLQENPETNIDLVL
CCCCCCCEEEEEECHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCEEEEE
LDVNMPVLDGLSTMKWIKENRPDLKVIALSVNDDEEIIIKMITNGAKGYLLKDTSPDIFK
EECCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCHHEEEEEECCCCCCEEEECCCCHHHH
DAIECVIEKGFYYTELVSGILINKVNSDNKKVNLKEKELVFIKHACTEMTYKEIASEMCL
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCHHHEEEEHHHHHHHHHHHHHHHHHC
SPKTIDGYRECLFDKLEIKTRIGLVLYAVKHKIVFV
CCCCCHHHHHHHHHHHHHHHHHHHHHEEEHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]