Click here to switch to the map view.

The map label for this gene is carD [H]

Identifier: 146300564

GI number: 146300564

Start: 3350276

End: 3351445

Strand: Direct

Name: carD [H]

Synonym: Fjoh_2814

Alternate gene names: 146300564

Gene position: 3350276-3351445 (Clockwise)

Preceding gene: 146300557

Following gene: 146300566

Centisome position: 54.95

GC content: 35.38

Gene sequence:

>1170_bases
ATGGAAAAAATATTCGATAACACTCAAGTTGCTTTTTCACTTAAAAGTGACACAGAACTTGACAGGGCTTATTTTCTTTT
TAAAATGATTGACAGTGAACCATTAGTAAGAATTGGAACAGCTGTTACCAATTTTGCTATTAAAGCACATCTTCCGGTTG
AAGGGTTAATTCGTGCTACTGTTTTTGATCATTTTTGCGGCGGTGTAAACGAAAATGACTGTTTAACTGTAGTTGATAAA
ATGTTTACAAAAGGCGTTTCATCTGTACTGGATTATTCAGTTGAAGGTAAAGAAGAAGAAGAGCAGTTTGATGCCGCTTT
AGAAATGACCTTAAAAACTATTGAATTTGCAAAAGAACGTTTAGCAATTCCTTTTGCAGTATTTAAACCAACAGGTTTAG
GACGTTTTGAATTGTATGAGAAATTAGGTGAGAAACAAACTTTAAGTCCTGCTGAACAAGAAGAATGGAATAGAGTAGTG
GCTCGTTTTGATCAGGTTTGCAGTGAAGCTCATAAAAAAGATGTGGCTTTATTAATTGATGGTGAAGAAAGCTGGATGCA
GGATGCTGCTGATGAATTGGTTACCGAAATGATGCGCAAATACAATAAAGAAAAAGCGATTATTTTCAACACACTTCAAA
TGTACCGTTGGGATCGTTTGGATTATTTAAAAGGACTGCACGAAATCGCTAAAAAAGAAGGTTTCTTTATTGGAATGAAA
TTAGTTCGCGGTGCTTATATGGAAAAAGAAAACAAGCGTGCAGAAGAAAAAGGTTATGTTTCGCCAATTTGTGTATCAAA
AGAAGCTACAGACATAAACTATGATGCTGCCGTTAATTATATGTTAGATCATATCGAAACTATGTCAATTTTTGCAGGAA
CTCATAACGAATTAAGTTCTTACAAACTTATGGAAAGTATGGCTCAAAAAGGCATTGCTAAAAATGACAACAGAATCTGG
TTTGGACAATTATACGGTATGAGCGATAATATAAGCTACAATCTAGCTGAAAACGGTTATAACGTAGCGAAATATCTTCC
GTTTGGACCTGTTAAAGATGTTATGCCGTACTTGATTCGCCGTGCTGAAGAAAATACTTCGGTAGCTGGGCAGACAAGCC
GTGAATTATCAATGATTAAAGCAGAACGTAAACGCAGAAAAGGGAAATAA

Upstream 100 bases:

>100_bases
AATACTAAATTTCTTTAACATTGATAATTTGTAAAAATTTCACACGATTTCGTAAAGAATATTCAAAACACTCCATATCT
TTGCACAAAAACTAAATTTA

Downstream 100 bases:

>100_bases
TTAGTTTTCAGTTTTCTGTCTCAGTTTACAGATTATATAAAAAAAGCTCCAATAAATATTGGAGCTTTTTTTATTCATTT
ATTTGAGTATTAAACCCGAC

Product: proline dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MEKIFDNTQVAFSLKSDTELDRAYFLFKMIDSEPLVRIGTAVTNFAIKAHLPVEGLIRATVFDHFCGGVNENDCLTVVDK
MFTKGVSSVLDYSVEGKEEEEQFDAALEMTLKTIEFAKERLAIPFAVFKPTGLGRFELYEKLGEKQTLSPAEQEEWNRVV
ARFDQVCSEAHKKDVALLIDGEESWMQDAADELVTEMMRKYNKEKAIIFNTLQMYRWDRLDYLKGLHEIAKKEGFFIGMK
LVRGAYMEKENKRAEEKGYVSPICVSKEATDINYDAAVNYMLDHIETMSIFAGTHNELSSYKLMESMAQKGIAKNDNRIW
FGQLYGMSDNISYNLAENGYNVAKYLPFGPVKDVMPYLIRRAEENTSVAGQTSRELSMIKAERKRRKGK

Sequences:

>Translated_389_residues
MEKIFDNTQVAFSLKSDTELDRAYFLFKMIDSEPLVRIGTAVTNFAIKAHLPVEGLIRATVFDHFCGGVNENDCLTVVDK
MFTKGVSSVLDYSVEGKEEEEQFDAALEMTLKTIEFAKERLAIPFAVFKPTGLGRFELYEKLGEKQTLSPAEQEEWNRVV
ARFDQVCSEAHKKDVALLIDGEESWMQDAADELVTEMMRKYNKEKAIIFNTLQMYRWDRLDYLKGLHEIAKKEGFFIGMK
LVRGAYMEKENKRAEEKGYVSPICVSKEATDINYDAAVNYMLDHIETMSIFAGTHNELSSYKLMESMAQKGIAKNDNRIW
FGQLYGMSDNISYNLAENGYNVAKYLPFGPVKDVMPYLIRRAEENTSVAGQTSRELSMIKAERKRRKGK
>Mature_389_residues
MEKIFDNTQVAFSLKSDTELDRAYFLFKMIDSEPLVRIGTAVTNFAIKAHLPVEGLIRATVFDHFCGGVNENDCLTVVDK
MFTKGVSSVLDYSVEGKEEEEQFDAALEMTLKTIEFAKERLAIPFAVFKPTGLGRFELYEKLGEKQTLSPAEQEEWNRVV
ARFDQVCSEAHKKDVALLIDGEESWMQDAADELVTEMMRKYNKEKAIIFNTLQMYRWDRLDYLKGLHEIAKKEGFFIGMK
LVRGAYMEKENKRAEEKGYVSPICVSKEATDINYDAAVNYMLDHIETMSIFAGTHNELSSYKLMESMAQKGIAKNDNRIW
FGQLYGMSDNISYNLAENGYNVAKYLPFGPVKDVMPYLIRRAEENTSVAGQTSRELSMIKAERKRRKGK

Specific function: Unknown

COG id: COG0506

COG function: function code E; Proline dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline oxidase family [H]

Homologues:

Organism=Homo sapiens, GI183227691, Length=227, Percent_Identity=40.9691629955947, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI10864043, Length=425, Percent_Identity=28.4705882352941, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71981541, Length=246, Percent_Identity=38.2113821138211, Blast_Score=178, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6323171, Length=370, Percent_Identity=23.7837837837838, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643721, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24643715, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24643719, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24643717, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI45556158, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI45556169, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI45556180, Length=249, Percent_Identity=37.3493975903614, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24643723, Length=249, Percent_Identity=37.3493975903614, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002872
- InterPro:   IPR015659 [H]

Pfam domain/function: PF01619 Pro_dh [H]

EC number: NA

Molecular weight: Translated: 44525; Mature: 44525

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIFDNTQVAFSLKSDTELDRAYFLFKMIDSEPLVRIGTAVTNFAIKAHLPVEGLIRAT
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCHHHHHHHH
VFDHFCGGVNENDCLTVVDKMFTKGVSSVLDYSVEGKEEEEQFDAALEMTLKTIEFAKER
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAIPFAVFKPTGLGRFELYEKLGEKQTLSPAEQEEWNRVVARFDQVCSEAHKKDVALLID
HCCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GEESWMQDAADELVTEMMRKYNKEKAIIFNTLQMYRWDRLDYLKGLHEIAKKEGFFIGMK
CCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHH
LVRGAYMEKENKRAEEKGYVSPICVSKEATDINYDAAVNYMLDHIETMSIFAGTHNELSS
HHHHHHHHHHHCCHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
YKLMESMAQKGIAKNDNRIWFGQLYGMSDNISYNLAENGYNVAKYLPFGPVKDVMPYLIR
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHH
RAEENTSVAGQTSRELSMIKAERKRRKGK
HHCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKIFDNTQVAFSLKSDTELDRAYFLFKMIDSEPLVRIGTAVTNFAIKAHLPVEGLIRAT
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCHHHHHHHH
VFDHFCGGVNENDCLTVVDKMFTKGVSSVLDYSVEGKEEEEQFDAALEMTLKTIEFAKER
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAIPFAVFKPTGLGRFELYEKLGEKQTLSPAEQEEWNRVVARFDQVCSEAHKKDVALLID
HCCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GEESWMQDAADELVTEMMRKYNKEKAIIFNTLQMYRWDRLDYLKGLHEIAKKEGFFIGMK
CCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHH
LVRGAYMEKENKRAEEKGYVSPICVSKEATDINYDAAVNYMLDHIETMSIFAGTHNELSS
HHHHHHHHHHHCCHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
YKLMESMAQKGIAKNDNRIWFGQLYGMSDNISYNLAENGYNVAKYLPFGPVKDVMPYLIR
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHHH
RAEENTSVAGQTSRELSMIKAERKRRKGK
HHCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9402024 [H]