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The map label for this gene is murQ [H]

Identifier: 146300245

GI number: 146300245

Start: 2976640

End: 2977452

Strand: Reverse

Name: murQ [H]

Synonym: Fjoh_2490

Alternate gene names: 146300245

Gene position: 2977452-2976640 (Counterclockwise)

Preceding gene: 146300248

Following gene: 146300244

Centisome position: 48.84

GC content: 39.24

Gene sequence:

>813_bases
ATGACATTTACGAAAACCACTGAACAATCATCAAAATACGAGCATTTAGAAAAAATGTCTGTTCATGAATTGTTATCAAA
TATTAATCAGGAAGACAAAACTGTTCCTTATGCAGTAGAAAAAGCTCTTCCGCAAATAGAAGCTTTAGTACCGCAAATCG
TGGCAAAATTAAAGCTGGGCGGAAGATTATTTTATATAGGAGCAGGAACTTCTGGCAGACTTGGTGTGGTAGATGCATCT
GAATGTCCTCCAACTTTTGGTGTTCCGTTTGATTTAGTAAATGGCATAATTGCCGGCGGCGATACTGCTATTCGTCGTGC
AGTAGAAAACGCCGAAGACAATGCAGCACAGGCGTGGATTGATTTGCAAGCGCATAATATTGGCGAAAATGATGTGGTTA
TAGGAATTGCGGCCTCTGGAACAACTCCGTATGTTATTGGCGGATTAGAGACTTGCAATCAAAATAATATTGTTACAGGC
TGTATTACAAACAATGCCGGAAGTCCGCTGGCGTTAACAGCAAAATTTCCAATTGAAGTTGTCGTGGGACCTGAATTTGT
TACCGGAAGTTCAAGAATGAAAGCCGGAACAGCTCAAAAACTGGTTTTAAATATGATTTCGACCGCTTCGATGATTCAGC
TTGGAAAAGTAAAAGGCAACAAAATGGTCGACATGCAGTTAAGCAACATAAAACTGGTTGATCGCGGCGTAAAAATGATT
ATGGGAGAAATTCCGGTTTCGTATGAAGAAGCTTCAGAATTATTAAAAAAATACGGCAGTGTAAGAAACGCTGTTGACAA
TTATATAAAGTAA

Upstream 100 bases:

>100_bases
TATACAGAAAAATAAGAAGAAAAAAAAGAGTATAAATCTTTGAGACTTTGCAAGATTGAGATAAAAAATATTAATTTTGA
CTGGTCTAAATAACACTAAA

Downstream 100 bases:

>100_bases
AAGGTTTTCTGCTTAGTTATTTAACCGCAAAGCGTGCAAAGGTTTTTCGCAAAGTACGCAAAGTTTAAATTAATAAATCT
TTGTCAAAATTTAAAACTTG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTFTKTTEQSSKYEHLEKMSVHELLSNINQEDKTVPYAVEKALPQIEALVPQIVAKLKLGGRLFYIGAGTSGRLGVVDAS
ECPPTFGVPFDLVNGIIAGGDTAIRRAVENAEDNAAQAWIDLQAHNIGENDVVIGIAASGTTPYVIGGLETCNQNNIVTG
CITNNAGSPLALTAKFPIEVVVGPEFVTGSSRMKAGTAQKLVLNMISTASMIQLGKVKGNKMVDMQLSNIKLVDRGVKMI
MGEIPVSYEEASELLKKYGSVRNAVDNYIK

Sequences:

>Translated_270_residues
MTFTKTTEQSSKYEHLEKMSVHELLSNINQEDKTVPYAVEKALPQIEALVPQIVAKLKLGGRLFYIGAGTSGRLGVVDAS
ECPPTFGVPFDLVNGIIAGGDTAIRRAVENAEDNAAQAWIDLQAHNIGENDVVIGIAASGTTPYVIGGLETCNQNNIVTG
CITNNAGSPLALTAKFPIEVVVGPEFVTGSSRMKAGTAQKLVLNMISTASMIQLGKVKGNKMVDMQLSNIKLVDRGVKMI
MGEIPVSYEEASELLKKYGSVRNAVDNYIK
>Mature_269_residues
TFTKTTEQSSKYEHLEKMSVHELLSNINQEDKTVPYAVEKALPQIEALVPQIVAKLKLGGRLFYIGAGTSGRLGVVDASE
CPPTFGVPFDLVNGIIAGGDTAIRRAVENAEDNAAQAWIDLQAHNIGENDVVIGIAASGTTPYVIGGLETCNQNNIVTGC
ITNNAGSPLALTAKFPIEVVVGPEFVTGSSRMKAGTAQKLVLNMISTASMIQLGKVKGNKMVDMQLSNIKLVDRGVKMIM
GEIPVSYEEASELLKKYGSVRNAVDNYIK

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=257, Percent_Identity=52.5291828793774, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28871; Mature: 28739

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTKTTEQSSKYEHLEKMSVHELLSNINQEDKTVPYAVEKALPQIEALVPQIVAKLKLG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GRLFYIGAGTSGRLGVVDASECPPTFGVPFDLVNGIIAGGDTAIRRAVENAEDNAAQAWI
CEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHCCEECCCHHHHHHHHHCCCCCCCEEEE
DLQAHNIGENDVVIGIAASGTTPYVIGGLETCNQNNIVTGCITNNAGSPLALTAKFPIEV
EEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCCCEEEEEECCEEE
VVGPEFVTGSSRMKAGTAQKLVLNMISTASMIQLGKVKGNKMVDMQLSNIKLVDRGVKMI
EECCCEECCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEHHHHHHHH
MGEIPVSYEEASELLKKYGSVRNAVDNYIK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFTKTTEQSSKYEHLEKMSVHELLSNINQEDKTVPYAVEKALPQIEALVPQIVAKLKLG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GRLFYIGAGTSGRLGVVDASECPPTFGVPFDLVNGIIAGGDTAIRRAVENAEDNAAQAWI
CEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHCCEECCCHHHHHHHHHCCCCCCCEEEE
DLQAHNIGENDVVIGIAASGTTPYVIGGLETCNQNNIVTGCITNNAGSPLALTAKFPIEV
EEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCCCEEEEEEECCCCCCEEEEEECCEEE
VVGPEFVTGSSRMKAGTAQKLVLNMISTASMIQLGKVKGNKMVDMQLSNIKLVDRGVKMI
EECCCEECCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEHHHHHHHH
MGEIPVSYEEASELLKKYGSVRNAVDNYIK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA