Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 146300158

GI number: 146300158

Start: 2877552

End: 2878130

Strand: Reverse

Name: yggV [C]

Synonym: Fjoh_2403

Alternate gene names: 146300158

Gene position: 2878130-2877552 (Counterclockwise)

Preceding gene: 146300160

Following gene: 146300157

Centisome position: 47.21

GC content: 34.72

Gene sequence:

>579_bases
ATGAAACTCGTTTTCGCTTCAAACAACAAAAATAAAATTGCAGAAATACAAAGCATGCTTCCTGAAAGTATTACAATATT
AAGTTTAGAAGATATTAATTGTTTTGAAGATATTCCTGAAACTGCAGATACAATTGAAGGAAATGCCATTTTGAAAGCGG
ATTACGTAACACAAAAGTATGGTTACGATTGTTTTGCAGATGATACTGGACTGGAAGTAGATGCTATAAATGGAGAACCC
GGAGTGTATTCTGCACGTTACGCAGGCGAGCAAAAAAATGCCGACGATAACATGAATAAACTTTTAAAGGCATTAGAAAA
CAACAAAAATCGAAGCGCTCAGTTTAAAACCGTTATCACTTTAAACCTGGAAGGAAAGCAATATATATTTACTGGAATTG
CAAAAGGAGAAATTACAGAAACCAAAACAGGTACAAATGGTTTTGGATACGACCCAATTTTCAAACCTGAAAATTTTGAC
AAAACCTTTGCAGAACTGCCTTTGGAAATAAAAAACACCATTGGACATCGTGGAAAAGCTGTTCAGCAACTAATTGATCT
CCTGACTGCCACAAAATAA

Upstream 100 bases:

>100_bases
TTTATATAAAACAGATAATTGCATTTATTTTATTTTTAGGCAGTATATCAAATATAAGAATTCTAAATTTGTGTTTAAAA
TCATTTAAACACTTAATTCT

Downstream 100 bases:

>100_bases
TTGTTTCAAATACAACATTTTAAAGCTCAAATTTTACATTTTCAGACGTGTTTTTGGGGCAAATTCTGGATTTTTTACAA
AAAATCATTTTACCTAAATC

Product: putative deoxyribonucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKYGYDCFADDTGLEVDAINGEP
GVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVITLNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFD
KTFAELPLEIKNTIGHRGKAVQQLIDLLTATK

Sequences:

>Translated_192_residues
MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKYGYDCFADDTGLEVDAINGEP
GVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVITLNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFD
KTFAELPLEIKNTIGHRGKAVQQLIDLLTATK
>Mature_192_residues
MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKYGYDCFADDTGLEVDAINGEP
GVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVITLNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFD
KTFAELPLEIKNTIGHRGKAVQQLIDLLTATK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=184, Percent_Identity=26.0869565217391, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=37.8238341968912, Blast_Score=119, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17556833, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322529, Length=197, Percent_Identity=33.502538071066, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=32.9787234042553, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_FLAJ1 (A5FH89)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194749.1
- ProteinModelPortal:   A5FH89
- SMR:   A5FH89
- STRING:   A5FH89
- GeneID:   5092135
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_2403
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   LEDINCF
- ProtClustDB:   PRK14823
- BioCyc:   FJOH376686:FJOH_2403-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21270; Mature: 21270

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKY
CEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHCCCHHHHCCCCEEEEECCHHHHC
GYDCFADDTGLEVDAINGEPGVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVIT
CCEEECCCCCCEEEEECCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
LNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFDKTFAELPLEIKNTIGHRGKA
EEECCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCHH
VQQLIDLLTATK
HHHHHHHHHCCC
>Mature Secondary Structure
MKLVFASNNKNKIAEIQSMLPESITILSLEDINCFEDIPETADTIEGNAILKADYVTQKY
CEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCHHHHCCCHHHHCCCCEEEEECCHHHHC
GYDCFADDTGLEVDAINGEPGVYSARYAGEQKNADDNMNKLLKALENNKNRSAQFKTVIT
CCEEECCCCCCEEEEECCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
LNLEGKQYIFTGIAKGEITETKTGTNGFGYDPIFKPENFDKTFAELPLEIKNTIGHRGKA
EEECCCEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCHH
VQQLIDLLTATK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA