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The map label for this gene is relE [H]

Identifier: 146284554

GI number: 146284554

Start: 39235

End: 39384

Strand: Direct

Name: relE [H]

Synonym: Ent638_4228

Alternate gene names: 146284554

Gene position: 39235-39384 (Clockwise)

Preceding gene: 146284553

Following gene: 146284570

Centisome position: 24.87

GC content: 43.33

Gene sequence:

>150_bases
ATGCATGACTGTTACAAAATTAAGCTCCGGTCTTCAGGCTATCGTCTTGTATATCAGGTCATAGACGAGAAGGTTGTCGT
CTTTGTGATTTCTGTTGGGAAAAGAGAGCGCTCGGAAGTTTATAGCGAGGCGGTCAAACACATTCTTTGA

Upstream 100 bases:

>100_bases
GGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAAAAAGAAGCTGGCTGAAGTGCTTGAGTAACCGCGAATTG
AAGCGAACAAGCTTCGGGGT

Downstream 100 bases:

>100_bases
TGCGCTGTACAAGAAACCGGGATTTCTGTTACGGGAAGCCACCCTGATGTTGAGAGTGAAATCCAGATAAGCCAGACACT
ACGCCGGCTCGGTGTACCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 49; Mature: 49

Protein sequence:

>49_residues
MHDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKHIL

Sequences:

>Translated_49_residues
MHDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKHIL
>Mature_49_residues
MHDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKHIL

Specific function: Inhibits translation during amino acid starvation. Acts by cleaving mRNA with high codon specificity in the ribosomal A site. UGA is cleaved with fast rate while UAA and UGA are cleaved with intermediate and slow rate, respectively. mRNA cleavage can also

COG id: COG2026

COG function: function code JD; Cytotoxic translational repressor of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787846, Length=49, Percent_Identity=95.9183673469388, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007712
- InterPro:   IPR012753 [H]

Pfam domain/function: PF05016 Plasmid_stabil [H]

EC number: NA

Molecular weight: Translated: 5772; Mature: 5772

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKHIL
CCCCEEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MHDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKHIL
CCCCEEEEECCCCHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574; 12526800 [H]