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The map label for this gene is yiaY [H]

Identifier: 145299820

GI number: 145299820

Start: 3126909

End: 3128060

Strand: Direct

Name: yiaY [H]

Synonym: ASA_2902

Alternate gene names: 145299820

Gene position: 3126909-3128060 (Clockwise)

Preceding gene: 145299818

Following gene: 145299831

Centisome position: 66.5

GC content: 61.81

Gene sequence:

>1152_bases
ATGGCGACATTCAAGTTCTATATTCCCGCAATCAACCTGATGGGAGCGGGCTGTCTGCAAGAGGCAGCGGCCGATATCAA
GGGTTATGGCTATCGCAAGGCGCTCATCGTCACCGACAAGATCCTCAACCAGATAGGCGTGGTCGCCAAGCTCACCACCC
TGCTGGCAGAACATGGCATTGAAAGCGTGGTTTTCGATGAAACCAAGCCGAACCCCACCATGACCAACGTCGAGTCGGGT
CTGGCCATGATCAGGGCCAACGGCTGCGACTGCGTCATCTCGCTGGGGGGCGGCTCACCCCATGACTGCGCCAAGGGCAT
CGCCCTGGTGGCCGCCAACGGTGGCAGCATCCAGGACTACGAAGGGGTGGATCGCTCCGCCAAACCGCAACTGCCGCTCA
TCGCCATCAACACCACAGCCGGCACTGCCTCCGAAATGACCCGTTTTTGCATCATCACGGACGAGGCGCGCCAGGTGAAG
ATGGCCATCATCGACAAGCACGTCACCCCGCTGATGTCGGTCAACGATCCCGAGCTGATGCTGGCCAAACCGGCCGGCCT
CACCGCCGCCACCGGCATGGATGCGCTGACCCACGCCATCGAGGCCTATGTCTCCACCATCGCCACCCCTGTGACCGATG
CCAGCGCCATCATGGCGATCCAGCTCATCGCCAAACACCTGCGCACCGCGGTCAATCAGGGTGATGACCTGCACGCCCGC
GAGCAGATGGCCTATGCCCAGTTCCTGGCCGGCATGGCCTTCAACAACGCAAGCCTGGGTTATGTGCACGCCATGGCGCA
CCAGCTGGGGGGCTTTTATGACCTGCCCCACGGTGTCTGCAACGCCGTGCTGCTGCCCCACGTTCAGGCATACAACGCCC
AGGTGAATGCCGCTCGCCTTAAAGATGTGGCCCGCTACATGGGCGTTGACGTGAGCACCATGAACGACGAACAGGGCGCC
GCTGCCGCCATTGCCGCCATCAAGCAGCTGGCGCTGGACGTGAAGATCCCGGCCGGTCTGGAGCAACTTGGCGTCAAGGC
CGATGATTTCGACGTGCTGGCCAGCAACGCCCTGAAAGATGCCTGCGGCTTCACCAACCCGAAACAGGCGAGCCACGAAG
AGATAGTCGCCATCTTCCGCGCCGCCATGTAA

Upstream 100 bases:

>100_bases
AAAGTTGCAAACAGGATACCATTGACCCCTTTTCATCCCCACTGACGATGCTATTTTGACGTCCGCATACCACTTAATGG
CTAATCATACGGAGTCCATC

Downstream 100 bases:

>100_bases
ACCGCATTGCCAATGGATAGGAAAAGGGGCCTGATCTGGCCCCTTTTTTCGCACTATTTCGTCAGCACCACATCGTTGAT
GGCGCTGGCCAATCGGGTCA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MATFKFYIPAINLMGAGCLQEAAADIKGYGYRKALIVTDKILNQIGVVAKLTTLLAEHGIESVVFDETKPNPTMTNVESG
LAMIRANGCDCVISLGGGSPHDCAKGIALVAANGGSIQDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARQVK
MAIIDKHVTPLMSVNDPELMLAKPAGLTAATGMDALTHAIEAYVSTIATPVTDASAIMAIQLIAKHLRTAVNQGDDLHAR
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVNAARLKDVARYMGVDVSTMNDEQGA
AAAIAAIKQLALDVKIPAGLEQLGVKADDFDVLASNALKDACGFTNPKQASHEEIVAIFRAAM

Sequences:

>Translated_383_residues
MATFKFYIPAINLMGAGCLQEAAADIKGYGYRKALIVTDKILNQIGVVAKLTTLLAEHGIESVVFDETKPNPTMTNVESG
LAMIRANGCDCVISLGGGSPHDCAKGIALVAANGGSIQDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARQVK
MAIIDKHVTPLMSVNDPELMLAKPAGLTAATGMDALTHAIEAYVSTIATPVTDASAIMAIQLIAKHLRTAVNQGDDLHAR
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVNAARLKDVARYMGVDVSTMNDEQGA
AAAIAAIKQLALDVKIPAGLEQLGVKADDFDVLASNALKDACGFTNPKQASHEEIVAIFRAAM
>Mature_382_residues
ATFKFYIPAINLMGAGCLQEAAADIKGYGYRKALIVTDKILNQIGVVAKLTTLLAEHGIESVVFDETKPNPTMTNVESGL
AMIRANGCDCVISLGGGSPHDCAKGIALVAANGGSIQDYEGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARQVKM
AIIDKHVTPLMSVNDPELMLAKPAGLTAATGMDALTHAIEAYVSTIATPVTDASAIMAIQLIAKHLRTAVNQGDDLHARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVNAARLKDVARYMGVDVSTMNDEQGAA
AAIAAIKQLALDVKIPAGLEQLGVKADDFDVLASNALKDACGFTNPKQASHEEIVAIFRAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=27.8728606356968, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=68.1462140992167, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1789163, Length=373, Percent_Identity=44.2359249329759, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=38.7267904509284, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1787493, Length=387, Percent_Identity=32.2997416020672, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789386, Length=354, Percent_Identity=23.1638418079096, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=412, Percent_Identity=24.5145631067961, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=53.2981530343008, Blast_Score=402, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=27.0731707317073, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40367; Mature: 40236

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFKFYIPAINLMGAGCLQEAAADIKGYGYRKALIVTDKILNQIGVVAKLTTLLAEHGI
CCEEEEECCHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCC
ESVVFDETKPNPTMTNVESGLAMIRANGCDCVISLGGGSPHDCAKGIALVAANGGSIQDY
CCEEECCCCCCCCHHHHHCCEEEEEECCCEEEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARQVKMAIIDKHVTPLMSVNDPELM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEE
LAKPAGLTAATGMDALTHAIEAYVSTIATPVTDASAIMAIQLIAKHLRTAVNQGDDLHAR
EECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVNAARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHH
KDVARYMGVDVSTMNDEQGAAAAIAAIKQLALDVKIPAGLEQLGVKADDFDVLASNALKD
HHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCHHHHHHHHHHH
ACGFTNPKQASHEEIVAIFRAAM
HHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ATFKFYIPAINLMGAGCLQEAAADIKGYGYRKALIVTDKILNQIGVVAKLTTLLAEHGI
CEEEEECCHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCC
ESVVFDETKPNPTMTNVESGLAMIRANGCDCVISLGGGSPHDCAKGIALVAANGGSIQDY
CCEEECCCCCCCCHHHHHCCEEEEEECCCEEEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPLIAINTTAGTASEMTRFCIITDEARQVKMAIIDKHVTPLMSVNDPELM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEE
LAKPAGLTAATGMDALTHAIEAYVSTIATPVTDASAIMAIQLIAKHLRTAVNQGDDLHAR
EECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
EQMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVNAARL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCCHHHHH
KDVARYMGVDVSTMNDEQGAAAAIAAIKQLALDVKIPAGLEQLGVKADDFDVLASNALKD
HHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHEEECCCCHHHHCCCCCCHHHHHHHHHHH
ACGFTNPKQASHEEIVAIFRAAM
HHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]