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The map label for this gene is hlyB [H]

Identifier: 145299791

GI number: 145299791

Start: 3096000

End: 3097712

Strand: Direct

Name: hlyB [H]

Synonym: ASA_2872

Alternate gene names: 145299791

Gene position: 3096000-3097712 (Clockwise)

Preceding gene: 145299790

Following gene: 145299797

Centisome position: 65.84

GC content: 59.37

Gene sequence:

>1713_bases
ATGGAACAGAACAGACCTGCCTTTCAACTCAATCTCTTGCTCTCCGTTGTTACCCTGATCCTGCTATCGCTGGTATTTTT
TGCCTACACCTGGTCAGGGACAAAACTCGAGCAGAGTTATCAACAACGCTACCAATCCTATCTGCTGGCCGATGAGCTAA
GGCAATCCTCCGACGATCTGACCCGGCTCGGTCGCACCTATGTGATCACCAAGGATCCCGCCTATGAGCAGCAGTACATG
CGGATCCTGGCCATACGCAACGGCGAACAGAACAGACCGGAAGGCTACAACCGCATCTATTGGGATTTCGTGGCGGCCAG
TGGTCAAAACCCCAGACCCGACACCTCGCTGCGGCGTGGCCTCATCGACCTGATGAAGGATGCCGGCTTTACCGATGGTG
AGCTGGCCAAGCTCAACGAGGCCAAGAACAACTCGGATGCCCTGGTCAGTACCGAAGTCGCTGCCTTCAAGCTGGTACAA
CAGCAGGAGGGGGATCTCGCGGTCAACCAGCAAAAAGCCATCGCCATGATGCATGACAAGGCCTATCACCAGAACAAGGG
GCGCATCATGGCCCCCATCGATGACTTCTACGTCATGATGGAGACCCGCACCCAGCAGGCGGTGGACGATGCCACCAGCC
AGTCTGCCATGTTGCGCTATCTGTTTATCGCCCTGGGCCTGGTATTGATGTTCTTCCTGTGGCGCACCTATCGTGCCCTG
CTCGACTTGACCGGTACCTCGGTCAGCCAGCTCAGAAGCGATCTCAACAGTCTGGCGCAAGGGGATTTCTCCCGTCAGAT
CCAGGTACCCGTTGGCGCACAAGAGAGCCTGATCGGCCTGCTGGCCACCATGCAGTCAACCCTCAAGGGGATCATCGCCC
AGGTCTCCCACTCCAGCGAGGAGCTGTCAGGATCGGCCGACAGCATAGCCCAGATAGCGGAGCGGACAGCCCAGTTTGCT
ACCTCCCAGCAGACCAGTACCCAGACAATGGCGGCCGCCATCGAGGAGCTGGTAGTGAGCATCAGCCACCTCTCCGACAA
CGCCACCCATGCCGACGAATTGAGCAAGGTGTCGGCCAACACCTTGGAAGAGGGTTCCGGCGTCATCAAGCAGACCCTGG
ACAGCATAGAGAACATCTCCAGCACAGTGGGAGATGCGGCCAGCAGCCTCTCCGAGCTCAACAGCCACACCCAGCAGATT
TCGGACATCATAGAGGTGATCCGCGGCATCGCCGATCAGACCAACCTGCTGGCCCTCAACGCCGCCATAGAGGCAGCGCG
GGCGGGAGAACAGGGACGGGGCTTTGCGGTGGTGGCCGACGAGGTGCGCAATCTCGCCAGCCGCTCGGCGGCCTCTACCC
AGCAGATCACCGGCATGATCAGCAAGATCCAGAGCGGGGCGGATGCCTCCATCCGCAGCATGGAGAATACGGTCAACAAC
GTCTCTCGCGGCGTGAGTCTGGCCAACCAGACCGGCGAGGCCATCACCAGCATCAAGAGTCATGCAGCCAACCTGACCGG
ATTGATGGGGGAGATAAGCCACACACTGCGCGAGCAATCCACCGCCGCCAACGAGGTAGTTTCCACCGTCGGCCACATCA
CCTCCCTCTCCGAACAGTCGGGGGATGCGGCCCGTCACGTATCGCAGGAGGCCGCCAAACTCAAACAGCTGTCACGGCTG
CTGCGCCAGGAGATGGGTCGCTTCAAATTGTAA

Upstream 100 bases:

>100_bases
CCCCCTATACTCACTGCAGAACAATAAAAACCCTCAGAAGTACCGGCCTTCGCCGTGTGACAAAGGGGGTTATTCTGGTG
AGAATAAGGACGCTCAAACC

Downstream 100 bases:

>100_bases
GCAGCTCCTGCAAAGCAAAACGGCTGCCCAAGGGCAGCCGTTTGTTTGGCAAGGCCTTTTTCAAGACCGGATGGCATCAA
CCACGCAGGGCGGCGATGCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MEQNRPAFQLNLLLSVVTLILLSLVFFAYTWSGTKLEQSYQQRYQSYLLADELRQSSDDLTRLGRTYVITKDPAYEQQYM
RILAIRNGEQNRPEGYNRIYWDFVAASGQNPRPDTSLRRGLIDLMKDAGFTDGELAKLNEAKNNSDALVSTEVAAFKLVQ
QQEGDLAVNQQKAIAMMHDKAYHQNKGRIMAPIDDFYVMMETRTQQAVDDATSQSAMLRYLFIALGLVLMFFLWRTYRAL
LDLTGTSVSQLRSDLNSLAQGDFSRQIQVPVGAQESLIGLLATMQSTLKGIIAQVSHSSEELSGSADSIAQIAERTAQFA
TSQQTSTQTMAAAIEELVVSISHLSDNATHADELSKVSANTLEEGSGVIKQTLDSIENISSTVGDAASSLSELNSHTQQI
SDIIEVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRSAASTQQITGMISKIQSGADASIRSMENTVNN
VSRGVSLANQTGEAITSIKSHAANLTGLMGEISHTLREQSTAANEVVSTVGHITSLSEQSGDAARHVSQEAAKLKQLSRL
LRQEMGRFKL

Sequences:

>Translated_570_residues
MEQNRPAFQLNLLLSVVTLILLSLVFFAYTWSGTKLEQSYQQRYQSYLLADELRQSSDDLTRLGRTYVITKDPAYEQQYM
RILAIRNGEQNRPEGYNRIYWDFVAASGQNPRPDTSLRRGLIDLMKDAGFTDGELAKLNEAKNNSDALVSTEVAAFKLVQ
QQEGDLAVNQQKAIAMMHDKAYHQNKGRIMAPIDDFYVMMETRTQQAVDDATSQSAMLRYLFIALGLVLMFFLWRTYRAL
LDLTGTSVSQLRSDLNSLAQGDFSRQIQVPVGAQESLIGLLATMQSTLKGIIAQVSHSSEELSGSADSIAQIAERTAQFA
TSQQTSTQTMAAAIEELVVSISHLSDNATHADELSKVSANTLEEGSGVIKQTLDSIENISSTVGDAASSLSELNSHTQQI
SDIIEVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRSAASTQQITGMISKIQSGADASIRSMENTVNN
VSRGVSLANQTGEAITSIKSHAANLTGLMGEISHTLREQSTAANEVVSTVGHITSLSEQSGDAARHVSQEAAKLKQLSRL
LRQEMGRFKL
>Mature_570_residues
MEQNRPAFQLNLLLSVVTLILLSLVFFAYTWSGTKLEQSYQQRYQSYLLADELRQSSDDLTRLGRTYVITKDPAYEQQYM
RILAIRNGEQNRPEGYNRIYWDFVAASGQNPRPDTSLRRGLIDLMKDAGFTDGELAKLNEAKNNSDALVSTEVAAFKLVQ
QQEGDLAVNQQKAIAMMHDKAYHQNKGRIMAPIDDFYVMMETRTQQAVDDATSQSAMLRYLFIALGLVLMFFLWRTYRAL
LDLTGTSVSQLRSDLNSLAQGDFSRQIQVPVGAQESLIGLLATMQSTLKGIIAQVSHSSEELSGSADSIAQIAERTAQFA
TSQQTSTQTMAAAIEELVVSISHLSDNATHADELSKVSANTLEEGSGVIKQTLDSIENISSTVGDAASSLSELNSHTQQI
SDIIEVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRSAASTQQITGMISKIQSGADASIRSMENTVNN
VSRGVSLANQTGEAITSIKSHAANLTGLMGEISHTLREQSTAANEVVSTVGHITSLSEQSGDAARHVSQEAAKLKQLSRL
LRQEMGRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=34.7701149425287, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI2367378, Length=345, Percent_Identity=31.8840579710145, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788195, Length=262, Percent_Identity=33.969465648855, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1787690, Length=398, Percent_Identity=28.894472361809, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=356, Percent_Identity=28.0898876404494, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62182; Mature: 62182

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNRPAFQLNLLLSVVTLILLSLVFFAYTWSGTKLEQSYQQRYQSYLLADELRQSSDDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
TRLGRTYVITKDPAYEQQYMRILAIRNGEQNRPEGYNRIYWDFVAASGQNPRPDTSLRRG
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHEECCCCCCCCCHHHHHH
LIDLMKDAGFTDGELAKLNEAKNNSDALVSTEVAAFKLVQQQEGDLAVNQQKAIAMMHDK
HHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
AYHQNKGRIMAPIDDFYVMMETRTQQAVDDATSQSAMLRYLFIALGLVLMFFLWRTYRAL
HHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLTGTSVSQLRSDLNSLAQGDFSRQIQVPVGAQESLIGLLATMQSTLKGIIAQVSHSSE
HHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELSGSADSIAQIAERTAQFATSQQTSTQTMAAAIEELVVSISHLSDNATHADELSKVSAN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TLEEGSGVIKQTLDSIENISSTVGDAASSLSELNSHTQQISDIIEVIRGIADQTNLLALN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAIEAARAGEQGRGFAVVADEVRNLASRSAASTQQITGMISKIQSGADASIRSMENTVNN
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VSRGVSLANQTGEAITSIKSHAANLTGLMGEISHTLREQSTAANEVVSTVGHITSLSEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDAARHVSQEAAKLKQLSRLLRQEMGRFKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQNRPAFQLNLLLSVVTLILLSLVFFAYTWSGTKLEQSYQQRYQSYLLADELRQSSDDL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
TRLGRTYVITKDPAYEQQYMRILAIRNGEQNRPEGYNRIYWDFVAASGQNPRPDTSLRRG
HHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHEECCCCCCCCCHHHHHH
LIDLMKDAGFTDGELAKLNEAKNNSDALVSTEVAAFKLVQQQEGDLAVNQQKAIAMMHDK
HHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
AYHQNKGRIMAPIDDFYVMMETRTQQAVDDATSQSAMLRYLFIALGLVLMFFLWRTYRAL
HHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLTGTSVSQLRSDLNSLAQGDFSRQIQVPVGAQESLIGLLATMQSTLKGIIAQVSHSSE
HHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
ELSGSADSIAQIAERTAQFATSQQTSTQTMAAAIEELVVSISHLSDNATHADELSKVSAN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TLEEGSGVIKQTLDSIENISSTVGDAASSLSELNSHTQQISDIIEVIRGIADQTNLLALN
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AAIEAARAGEQGRGFAVVADEVRNLASRSAASTQQITGMISKIQSGADASIRSMENTVNN
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VSRGVSLANQTGEAITSIKSHAANLTGLMGEISHTLREQSTAANEVVSTVGHITSLSEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GDAARHVSQEAAKLKQLSRLLRQEMGRFKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]