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The map label for this gene is nagB [H]

Identifier: 145299751

GI number: 145299751

Start: 3031715

End: 3032515

Strand: Direct

Name: nagB [H]

Synonym: ASA_2828

Alternate gene names: 145299751

Gene position: 3031715-3032515 (Clockwise)

Preceding gene: 145299747

Following gene: 145299752

Centisome position: 64.47

GC content: 58.93

Gene sequence:

>801_bases
ATGCGCCTGATCCCGTTGAAATCTGCCAGCCAAGTGGGTCTGTGGTCTGCCCGTTACATCGTTGACCGTATCAATGGGTT
CAAACCCACTGCCGATCGCCCCTTCGTACTGGGCCTGCCCACCGGCGGCACCCCGCTCAACACTTACAAGCGCCTGATCG
AGCTGCATAAAGCCGGTGAAGTAAGTTTCGAGCACGTGGCCACCTTCAACATGGACGAATATGTCGGCCTGCCGGAAGAT
CACCCGGAGAGCTACCACAGCTTCATGCACAACAACTTCTTCTGTCACATCGACATTCGCCCGGAAAACATCAACATCCT
CAACGGCAACGCCGAGGATCTGGTGGCCGAGTGCAAGCGCTATGAGGACAAGATCAAGTCCTATGGCAAGATCAACCTCT
TCATGGGCGGCGTCGGCAATGACGGTCACATAGCGTTCAACGAACCGGCCTCCTCCCTCTCCTCCCGCACCCGGGTCAAG
ACCCTGACCGAGGACACCCGCATCGCCAACTCCCGCTTCTTCGGCGGTGACATGGAGCAGGTGCCCAAGCTGGCGCTGAC
TGTGGGTGTCGGCACCCTGATGGACGCCGAAGAGATCATGATCCTGGTCACTGGCCACGGCAAGGCCCAGGCCCTGCAAG
CAGCAGTGGAAGGCAGCGTCAACCACATGTGGACCATCTCCACCCTGCAACTGCATCCGAAGGGAATGATGGTGTGCGAC
GAGCCCTCCACCATGGAGCTCAAGGTCAAGACGGTGCGTTACTTCCAGCAGCTCGAAGCCGCCAACATCGGCCGTCTGTA
A

Upstream 100 bases:

>100_bases
CTTAGTTCGCAATCTTTATTTACGCTATAAAACAACTTGAATCCGTCTTAGCCTATTTGCCGCCGACACCCCGGCAGCAA
CCCGTACAGAGGTATCTACA

Downstream 100 bases:

>100_bases
GGAGCCACCATGTACGCATTGACCAATTGCACCCTCTACACCGGCAGCTGTGTGCTGACCGGTTACGGGGTCGTGATCGA
GGGCGACAAGATTGTCGCCA

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRLIPLKSASQVGLWSARYIVDRINGFKPTADRPFVLGLPTGGTPLNTYKRLIELHKAGEVSFEHVATFNMDEYVGLPED
HPESYHSFMHNNFFCHIDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRVK
TLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHGKAQALQAAVEGSVNHMWTISTLQLHPKGMMVCD
EPSTMELKVKTVRYFQQLEAANIGRL

Sequences:

>Translated_266_residues
MRLIPLKSASQVGLWSARYIVDRINGFKPTADRPFVLGLPTGGTPLNTYKRLIELHKAGEVSFEHVATFNMDEYVGLPED
HPESYHSFMHNNFFCHIDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRVK
TLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHGKAQALQAAVEGSVNHMWTISTLQLHPKGMMVCD
EPSTMELKVKTVRYFQQLEAANIGRL
>Mature_266_residues
MRLIPLKSASQVGLWSARYIVDRINGFKPTADRPFVLGLPTGGTPLNTYKRLIELHKAGEVSFEHVATFNMDEYVGLPED
HPESYHSFMHNNFFCHIDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRVK
TLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHGKAQALQAAVEGSVNHMWTISTLQLHPKGMMVCD
EPSTMELKVKTVRYFQQLEAANIGRL

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=63.953488372093, Blast_Score=349, Evalue=1e-96,
Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=62.4031007751938, Blast_Score=344, Evalue=4e-95,
Organism=Escherichia coli, GI1786893, Length=266, Percent_Identity=78.1954887218045, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1789530, Length=235, Percent_Identity=27.6595744680851, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI48994958, Length=240, Percent_Identity=27.0833333333333, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554876, Length=258, Percent_Identity=59.3023255813954, Blast_Score=314, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24581960, Length=256, Percent_Identity=64.0625, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19920764, Length=256, Percent_Identity=64.0625, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29625; Mature: 29625

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIPLKSASQVGLWSARYIVDRINGFKPTADRPFVLGLPTGGTPLNTYKRLIELHKAGE
CEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
VSFEHVATFNMDEYVGLPEDHPESYHSFMHNNFFCHIDIRPENINILNGNAEDLVAECKR
CCCHHEEEECHHHHCCCCCCCHHHHHHHHHCCEEEEEEEECCEEEEECCCHHHHHHHHHH
YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRVKTLTEDTRIANSRFFGGDMEQ
HHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VPKLALTVGVGTLMDAEEIMILVTGHGKAQALQAAVEGSVNHMWTISTLQLHPKGMMVCD
HHHEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEC
EPSTMELKVKTVRYFQQLEAANIGRL
CCCCEEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLIPLKSASQVGLWSARYIVDRINGFKPTADRPFVLGLPTGGTPLNTYKRLIELHKAGE
CEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCC
VSFEHVATFNMDEYVGLPEDHPESYHSFMHNNFFCHIDIRPENINILNGNAEDLVAECKR
CCCHHEEEECHHHHCCCCCCCHHHHHHHHHCCEEEEEEEECCEEEEECCCHHHHHHHHHH
YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRVKTLTEDTRIANSRFFGGDMEQ
HHHHHHCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VPKLALTVGVGTLMDAEEIMILVTGHGKAQALQAAVEGSVNHMWTISTLQLHPKGMMVCD
HHHEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCEEEC
EPSTMELKVKTVRYFQQLEAANIGRL
CCCCEEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA