| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is lysA [C]
Identifier: 145296096
GI number: 145296096
Start: 2219738
End: 2222392
Strand: Reverse
Name: lysA [C]
Synonym: cgR_2017
Alternate gene names: 145296096
Gene position: 2222392-2219738 (Counterclockwise)
Preceding gene: 145296097
Following gene: 145296095
Centisome position: 67.06
GC content: 49.72
Gene sequence:
>2655_bases ATGGGTGGAGGAAAACCTTTGTTCAAGGTAGCTATCATTGGTGGCGGACCGCGCGGGTTGTGGGCTGCTGAAGAATTACT AGCTCTTGCTAGGGAGAGAGGAGCCAGCATTGATCTTCATGTTTTTAATGATGGTCTCGGTGTGGCATATCAACCTGATC AGCCTGAAGAATGGCTGATAAATGTACGATCTTCCACGATTACTACACAGTTCAGCGACTTCAGTCAATGGCTACGAAAA CGCAATGTAGATTCATCTTTCCCACCTCGACGATTAGTAGGGGAGTTCCTGGAAGAATCTTGGGATGCGCTTCTTGAATA TGTACCTCAGGGGTGTTCTCTTACGATGCACACTAAACATGTAGACACAATCAAACCCTGCGGTAAAAAGAGTGAACGTT GGTTAGTGCAGGAACAAGAGTTTGATGAAATTCTTTTAGCTACTGGACATGCACACGATTGGCCTGGATCCTTATCGCAA GAAGATTTCCCTGAGTCAGTACGCCTGATCGCATCTCCTTATCCTGCTAATAATCTAGACGGGATCAAGTCCACAGACAG AGTGTTAGTGCGTGGGGCAGCTCTCACTTTCATCGACATCACTCGAGTATGCTCACCGGCCGTATTCATTCCAATAACCC GCACAGGGAAACTAATGATACCGAAGCCCGACGTGACTGACTTATATTTAGAGGACCTCTTAAATGAGGGTTCGGAAAAT ATTCGGTCCGCCAAGGATCTTTCCGAACTTAGGACAGTTCTAAAAGAGGTTTCCTCCCAAATTCAGGAACGAGCTGGGAA AAAAGATGAAGAATGGGGAATGGGGGCTACTTGGCGGGAGCTGTACCCAAGCATCGTGGAACGCGCTTCATACGAAGGGC GTGACAGCTTGAAGGGGTTTGATCACTTAGCCCGGGAAATGGAAAGACTAGCCTTCGGCCCACCACCCGAAAGTTTTAAC TACCTCCAAGAACTCGTAAAATCCGGAGTGGTAGACATCACTCACCTGCATCGTGGCCGGGAACCACTGGCAGATTTGGT TCGTGAACTTGAAATAACTGTGGTGATAGACGCAGTTATTCCCCCACCGGGAGTAGTGCCAGGCACATTGGTGCACAATT TGGTAAAAGAGGGATATGCCAGAATCCGTCCTGGGACTCGGGGGTTAGATGTAGCGGCTGACGGCACCGTTCAAGGGCAG CAACATTTGGCTGCAGTCGGACGGATGACGGAAGATGTGGTTTTGGGTAATGACACATTGTCGCGGTCATTGCATGACAT AATCCCGAAGTGGGCTCGGCGAGTTGTCCGCGACGCGAGTACGTATCCCAATAGGGTGCATGGTATTCCACCGCTTCCGG CACGGTTGGAACCCTGGGCGGAAAAGCTCACTTCAGATCCGGCCACATGCCGCCACCTGATTGAAGAATTCGGGAGTCCT GTGAATGTACTCCATTCAGGTTCTATGCCTCGTAATATAAATGAGTTGGTTGACGCCGGCATTGAGATGGGGGTGGATAC TCGAATATTTTTTGCCCGTAAAGCGAATAAGGGTCTTACCTTCGTCGATGCCGTTAAAGACACCGGTCATGGTGTAGATG TAGCCAGTGAACGAGAGTTATCTCAGGTGCTTAATCGTGGAGTCCCAGGAGAGCGGATCATTCTATCCGCAGCTATCAAA CCGGACAGACTATTAGCATTAGCGATCGAAAATGGCGTGATCATCTCTGTGGATTCGCGTGATGAATTAGATCGCATTTC GGCTTTGGTTGGCGACCGCGTTGCACGAGTTGCGCCTAGAGTAGCTCCAGATCCTGCAGTCTTACCTCCAACTAGATTTG GTGAGCGAGCCGCAGACTGGGGTAATCGGCTTACCGAGGTGATACCCGGCGTGGATATTGTGGGTCTTCACGTTCACCTT CATGGCTATGCTGCAAAAGACCGTGCTCTAGCTCTACAGGAATGTTGCCAACTCGTCGATTCTCTCAGAGAATGCGGGCA TTCCCCACAGTTTATTGACCTTGGAGGAGGGGTACCTATGAGCTACATTGAATCTGAGGAAGATTGGATCCGTTATCAAT CCGCTAAATCTGCGACTTCAGCCGGGTATGCCGAATCCTTTACGTGGAAAGACGATCCGTTATCTAATACGTACCCGTTC TATCAGACCCCAGTGCGCGGTAATTGGTTGAAAGATGTGCTTTCTAAGGGGGTAGCCCAGATGCTCATTGACCGGGGATT GCGGTTACACCTAGAGCCTGGTCGAAGTTTACTAGATGGGTGTGGCGTCACTCTTGCCGAAGTTGCTTTTGTGAAAACCC GAAGTGACGGGTTGCCTCTAGTGGGACTGGCTATGAACCGAACGCAGTGCCGGACTACATCCGATGATTTTCTCATTGAT CCCCTGCATATCACTGACGGTGATGTAGGTGAGGAAATCGAAGCATATCTAGTGGGTGCCTACTGCATCGAAGATGAGCT GATTTTACGCCGGCGAATCCGCTTCCCGAGAGGAATCAAACCAGGAGATATCATCGGAATTCCTAACACCGCAGGATACT TCATGCATATCTTGGAAAGTGCATCGCACCAAATCCCGTTGGCGAAAAATGTAGTGTGGCCGGAGGGGCAGTTAGACGAT ATCGATGCGGATTAA
Upstream 100 bases:
>100_bases CTATGGAGATATTACGCCCCGACATCCCTGCGGGTAGCAATGTAGTAGTAATTCTTCATGATGACGGAAATAAGTATTTA GATACGATTTATAACGACGA
Downstream 100 bases:
>100_bases GACATAACCATTCGCTAATCTTTCGACGCCCCTTCTGAGGTGGGGATTTCTTTTCATCCCCTTTAATTATTTTCGGAAAT TTAAACAACAATCCTCGAAA
Product: hypothetical protein
Products: L-lysine; CO2
Alternate protein names: NA
Number of amino acids: Translated: 884; Mature: 883
Protein sequence:
>884_residues MGGGKPLFKVAIIGGGPRGLWAAEELLALARERGASIDLHVFNDGLGVAYQPDQPEEWLINVRSSTITTQFSDFSQWLRK RNVDSSFPPRRLVGEFLEESWDALLEYVPQGCSLTMHTKHVDTIKPCGKKSERWLVQEQEFDEILLATGHAHDWPGSLSQ EDFPESVRLIASPYPANNLDGIKSTDRVLVRGAALTFIDITRVCSPAVFIPITRTGKLMIPKPDVTDLYLEDLLNEGSEN IRSAKDLSELRTVLKEVSSQIQERAGKKDEEWGMGATWRELYPSIVERASYEGRDSLKGFDHLAREMERLAFGPPPESFN YLQELVKSGVVDITHLHRGREPLADLVRELEITVVIDAVIPPPGVVPGTLVHNLVKEGYARIRPGTRGLDVAADGTVQGQ QHLAAVGRMTEDVVLGNDTLSRSLHDIIPKWARRVVRDASTYPNRVHGIPPLPARLEPWAEKLTSDPATCRHLIEEFGSP VNVLHSGSMPRNINELVDAGIEMGVDTRIFFARKANKGLTFVDAVKDTGHGVDVASERELSQVLNRGVPGERIILSAAIK PDRLLALAIENGVIISVDSRDELDRISALVGDRVARVAPRVAPDPAVLPPTRFGERAADWGNRLTEVIPGVDIVGLHVHL HGYAAKDRALALQECCQLVDSLRECGHSPQFIDLGGGVPMSYIESEEDWIRYQSAKSATSAGYAESFTWKDDPLSNTYPF YQTPVRGNWLKDVLSKGVAQMLIDRGLRLHLEPGRSLLDGCGVTLAEVAFVKTRSDGLPLVGLAMNRTQCRTTSDDFLID PLHITDGDVGEEIEAYLVGAYCIEDELILRRRIRFPRGIKPGDIIGIPNTAGYFMHILESASHQIPLAKNVVWPEGQLDD IDAD
Sequences:
>Translated_884_residues MGGGKPLFKVAIIGGGPRGLWAAEELLALARERGASIDLHVFNDGLGVAYQPDQPEEWLINVRSSTITTQFSDFSQWLRK RNVDSSFPPRRLVGEFLEESWDALLEYVPQGCSLTMHTKHVDTIKPCGKKSERWLVQEQEFDEILLATGHAHDWPGSLSQ EDFPESVRLIASPYPANNLDGIKSTDRVLVRGAALTFIDITRVCSPAVFIPITRTGKLMIPKPDVTDLYLEDLLNEGSEN IRSAKDLSELRTVLKEVSSQIQERAGKKDEEWGMGATWRELYPSIVERASYEGRDSLKGFDHLAREMERLAFGPPPESFN YLQELVKSGVVDITHLHRGREPLADLVRELEITVVIDAVIPPPGVVPGTLVHNLVKEGYARIRPGTRGLDVAADGTVQGQ QHLAAVGRMTEDVVLGNDTLSRSLHDIIPKWARRVVRDASTYPNRVHGIPPLPARLEPWAEKLTSDPATCRHLIEEFGSP VNVLHSGSMPRNINELVDAGIEMGVDTRIFFARKANKGLTFVDAVKDTGHGVDVASERELSQVLNRGVPGERIILSAAIK PDRLLALAIENGVIISVDSRDELDRISALVGDRVARVAPRVAPDPAVLPPTRFGERAADWGNRLTEVIPGVDIVGLHVHL HGYAAKDRALALQECCQLVDSLRECGHSPQFIDLGGGVPMSYIESEEDWIRYQSAKSATSAGYAESFTWKDDPLSNTYPF YQTPVRGNWLKDVLSKGVAQMLIDRGLRLHLEPGRSLLDGCGVTLAEVAFVKTRSDGLPLVGLAMNRTQCRTTSDDFLID PLHITDGDVGEEIEAYLVGAYCIEDELILRRRIRFPRGIKPGDIIGIPNTAGYFMHILESASHQIPLAKNVVWPEGQLDD IDAD >Mature_883_residues GGGKPLFKVAIIGGGPRGLWAAEELLALARERGASIDLHVFNDGLGVAYQPDQPEEWLINVRSSTITTQFSDFSQWLRKR NVDSSFPPRRLVGEFLEESWDALLEYVPQGCSLTMHTKHVDTIKPCGKKSERWLVQEQEFDEILLATGHAHDWPGSLSQE DFPESVRLIASPYPANNLDGIKSTDRVLVRGAALTFIDITRVCSPAVFIPITRTGKLMIPKPDVTDLYLEDLLNEGSENI RSAKDLSELRTVLKEVSSQIQERAGKKDEEWGMGATWRELYPSIVERASYEGRDSLKGFDHLAREMERLAFGPPPESFNY LQELVKSGVVDITHLHRGREPLADLVRELEITVVIDAVIPPPGVVPGTLVHNLVKEGYARIRPGTRGLDVAADGTVQGQQ HLAAVGRMTEDVVLGNDTLSRSLHDIIPKWARRVVRDASTYPNRVHGIPPLPARLEPWAEKLTSDPATCRHLIEEFGSPV NVLHSGSMPRNINELVDAGIEMGVDTRIFFARKANKGLTFVDAVKDTGHGVDVASERELSQVLNRGVPGERIILSAAIKP DRLLALAIENGVIISVDSRDELDRISALVGDRVARVAPRVAPDPAVLPPTRFGERAADWGNRLTEVIPGVDIVGLHVHLH GYAAKDRALALQECCQLVDSLRECGHSPQFIDLGGGVPMSYIESEEDWIRYQSAKSATSAGYAESFTWKDDPLSNTYPFY QTPVRGNWLKDVLSKGVAQMLIDRGLRLHLEPGRSLLDGCGVTLAEVAFVKTRSDGLPLVGLAMNRTQCRTTSDDFLIDP LHITDGDVGEEIEAYLVGAYCIEDELILRRRIRFPRGIKPGDIIGIPNTAGYFMHILESASHQIPLAKNVVWPEGQLDDI DAD
Specific function: Lysine biosynthesis; last step. [C]
COG id: COG4529
COG function: function code S; Uncharacterized protein conserved in bacteria
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR022643 - InterPro: IPR022644 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: 4.1.1.20
Molecular weight: Translated: 97613; Mature: 97482
Theoretical pI: Translated: 5.18; Mature: 5.18
Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGGGKPLFKVAIIGGGPRGLWAAEELLALARERGASIDLHVFNDGLGVAYQPDQPEEWLI CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCCCHHHHE NVRSSTITTQFSDFSQWLRKRNVDSSFPPRRLVGEFLEESWDALLEYVPQGCSLTMHTKH EECCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC VDTIKPCGKKSERWLVQEQEFDEILLATGHAHDWPGSLSQEDFPESVRLIASPYPANNLD CCHHCCCCCCCHHCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCC GIKSTDRVLVRGAALTFIDITRVCSPAVFIPITRTGKLMIPKPDVTDLYLEDLLNEGSEN CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCHHHHHHHHHHHCCHHH IRSAKDLSELRTVLKEVSSQIQERAGKKDEEWGMGATWRELYPSIVERASYEGRDSLKGF HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH DHLAREMERLAFGPPPESFNYLQELVKSGVVDITHLHRGREPLADLVRELEITVVIDAVI HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEHHHHHCCCHHHHHHHHHCEEEEEEEECC PPPGVVPGTLVHNLVKEGYARIRPGTRGLDVAADGTVQGQQHLAAVGRMTEDVVLGNDTL CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCEEECCHHH SRSLHDIIPKWARRVVRDASTYPNRVHGIPPLPARLEPWAEKLTSDPATCRHLIEEFGSP HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCC VNVLHSGSMPRNINELVDAGIEMGVDTRIFFARKANKGLTFVDAVKDTGHGVDVASEREL EEEHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEHHHCCCCCCCCCCHHHH SQVLNRGVPGERIILSAAIKPDRLLALAIENGVIISVDSRDELDRISALVGDRVARVAPR HHHHHCCCCCCEEEEEECCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCC VAPDPAVLPPTRFGERAADWGNRLTEVIPGVDIVGLHVHLHGYAAKDRALALQECCQLVD CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHH SLRECGHSPQFIDLGGGVPMSYIESEEDWIRYQSAKSATSAGYAESFTWKDDPLSNTYPF HHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC YQTPVRGNWLKDVLSKGVAQMLIDRGLRLHLEPGRSLLDGCGVTLAEVAFVKTRSDGLPL EECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCHHHHHHHHHEECCCCCCE VGLAMNRTQCRTTSDDFLIDPLHITDGDVGEEIEAYLVGAYCIEDELILRRRIRFPRGIK EEEECCCCCCCCCCCCEEEECEECCCCCCCHHHHHHEEEHHHHHHHHHHHHHHCCCCCCC PGDIIGIPNTAGYFMHILESASHQIPLAKNVVWPEGQLDDIDAD CCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure GGGKPLFKVAIIGGGPRGLWAAEELLALARERGASIDLHVFNDGLGVAYQPDQPEEWLI CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCEEECCCCCHHHHE NVRSSTITTQFSDFSQWLRKRNVDSSFPPRRLVGEFLEESWDALLEYVPQGCSLTMHTKH EECCCCEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC VDTIKPCGKKSERWLVQEQEFDEILLATGHAHDWPGSLSQEDFPESVRLIASPYPANNLD CCHHCCCCCCCHHCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCC GIKSTDRVLVRGAALTFIDITRVCSPAVFIPITRTGKLMIPKPDVTDLYLEDLLNEGSEN CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCHHHHHHHHHHHCCHHH IRSAKDLSELRTVLKEVSSQIQERAGKKDEEWGMGATWRELYPSIVERASYEGRDSLKGF HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH DHLAREMERLAFGPPPESFNYLQELVKSGVVDITHLHRGREPLADLVRELEITVVIDAVI HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEHHHHHCCCHHHHHHHHHCEEEEEEEECC PPPGVVPGTLVHNLVKEGYARIRPGTRGLDVAADGTVQGQQHLAAVGRMTEDVVLGNDTL CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCEEECCHHH SRSLHDIIPKWARRVVRDASTYPNRVHGIPPLPARLEPWAEKLTSDPATCRHLIEEFGSP HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCC VNVLHSGSMPRNINELVDAGIEMGVDTRIFFARKANKGLTFVDAVKDTGHGVDVASEREL EEEHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEHHHCCCCCCCCCCHHHH SQVLNRGVPGERIILSAAIKPDRLLALAIENGVIISVDSRDELDRISALVGDRVARVAPR HHHHHCCCCCCEEEEEECCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCCC VAPDPAVLPPTRFGERAADWGNRLTEVIPGVDIVGLHVHLHGYAAKDRALALQECCQLVD CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHH SLRECGHSPQFIDLGGGVPMSYIESEEDWIRYQSAKSATSAGYAESFTWKDDPLSNTYPF HHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC YQTPVRGNWLKDVLSKGVAQMLIDRGLRLHLEPGRSLLDGCGVTLAEVAFVKTRSDGLPL EECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCHHHHHHHHHEECCCCCCE VGLAMNRTQCRTTSDDFLIDPLHITDGDVGEEIEAYLVGAYCIEDELILRRRIRFPRGIK EEEECCCCCCCCCCCCEEEECEECCCCCCCHHHHHHEEEHHHHHHHHHHHHHHCCCCCCC PGDIIGIPNTAGYFMHILESASHQIPLAKNVVWPEGQLDDIDAD CCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: D-Lysine; Pyridoxal 5'-phosphate [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 1.7 {meso-2,6-diamininoheptanedioate}} [C]
Substrates: meso-2,6-diaminoheptanedioate
Specific reaction: meso-2,6-diaminoheptanedioate = L-lysine + CO2
General reaction: Decarboxylation [C]
Inhibitor: 2, 3-Diaminopropionic acid; Glutamic acid; L-Cystine; L-Lysine; Penicillamine [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9163424 [H]