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The map label for this gene is ribF [H]

Identifier: 145295882

GI number: 145295882

Start: 2005942

End: 2006967

Strand: Reverse

Name: ribF [H]

Synonym: cgR_1807

Alternate gene names: 145295882

Gene position: 2006967-2005942 (Counterclockwise)

Preceding gene: 145295884

Following gene: 145295881

Centisome position: 60.56

GC content: 56.53

Gene sequence:

>1026_bases
GTGGATATTTGGAGTGGACTAGACAGCGTTCCGGCTGATCTTCAAGGATCGGTAGTCACCATTGGTGTATTTGATGGGCT
CCACCGGGGGCATCAAAGTTTAATCGGCGAGGCCAAGAAGCAGGCCGAGGAGCTGGGTGTGCCTTGTGTCATGGTGACCT
TTGACCCGCATCCGATCGCTGTGTTTTTGCCAGGTAAAGAGCCAACCCGTTTAGCTCCTTTGGATTATCGCCTTAATTTG
GCTGCGGAATGTGGCGTCGATGCTGCGTTGGTTATTGATTTCACTAAAGAACTCGCAGGTCTGAGCGCTGAAGAGTATTT
CACAACCATGATCGTGGATACGCTGCATGCGCGTTCAGTTGTGGTGGGGGAGAACTTCACCTTCGGTGTCAATGGCGCTG
GCACTGAGTCCACGATGCGGGAATTGGGACAAAAGTTTGGCGTGAATGTCACGATTGCTCCGCTGCTGCATGATGATGAC
CAGCGTATTTGCTCCACCTTGGTGCGCGATTACTTGGATCAGGGCGAGGTTGAGCGCGCGAACTGGGCGCTTGGTCGACG
CTATGCCGTGCGCGGCGAAGTTGTCCGTGGTGCTGGCCGTGGCGGCAAAGAATTGGGCTATCCCACCGCGAATCTCTACC
TGCCGACCTCTGTGGCGCTGCCCGCCGACGGCGTGTATGCAGGCTGGTTCACCATCACCGATGACCGCGAAATCGACAAG
GAAATCTCCCGCGATATCGACGGCACCATGGTTCCAGGCGTGCGTTACCAAACTGCCATTTCCGTGGGCACCAATCCCAC
CTTCGGCGATGAGCGACGCAGCGTCGAGGCATTCATCCTCGACCAGGAAGCCGACCTGTACGGTCACCATGTCATGGTGG
AATTCGTGGGACACTTGCGCGACATGGTCAAATTCAACGGCGTCGACGAGCTACTAGACGCCATGGCCCGCGATGTCACC
AACGCCCGCGACATCCTTGCCAAAGACAAATTGCTTCTCGACGCCGACACCCAGCCCAGCGCTTAA

Upstream 100 bases:

>100_bases
GTCATGGGATGTCATTCCGGCGGGCTTGTCGACGATCACGAGTCCAGGTTTAGGGGCAGGAGCATTCATGTCTGTTGAGT
CTATGCCGTAGTCTAAAACA

Downstream 100 bases:

>100_bases
GGCCGGTCACCGGCCATCAAGCTTGTCACATCGGGTGCCTTATGATGGTGCCCGACCTTAAAAATAAAAACCTGAAAGGT
TAAAAACGCATGAGCAAAAA

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MDIWSGLDSVPADLQGSVVTIGVFDGLHRGHQSLIGEAKKQAEELGVPCVMVTFDPHPIAVFLPGKEPTRLAPLDYRLNL
AAECGVDAALVIDFTKELAGLSAEEYFTTMIVDTLHARSVVVGENFTFGVNGAGTESTMRELGQKFGVNVTIAPLLHDDD
QRICSTLVRDYLDQGEVERANWALGRRYAVRGEVVRGAGRGGKELGYPTANLYLPTSVALPADGVYAGWFTITDDREIDK
EISRDIDGTMVPGVRYQTAISVGTNPTFGDERRSVEAFILDQEADLYGHHVMVEFVGHLRDMVKFNGVDELLDAMARDVT
NARDILAKDKLLLDADTQPSA

Sequences:

>Translated_341_residues
MDIWSGLDSVPADLQGSVVTIGVFDGLHRGHQSLIGEAKKQAEELGVPCVMVTFDPHPIAVFLPGKEPTRLAPLDYRLNL
AAECGVDAALVIDFTKELAGLSAEEYFTTMIVDTLHARSVVVGENFTFGVNGAGTESTMRELGQKFGVNVTIAPLLHDDD
QRICSTLVRDYLDQGEVERANWALGRRYAVRGEVVRGAGRGGKELGYPTANLYLPTSVALPADGVYAGWFTITDDREIDK
EISRDIDGTMVPGVRYQTAISVGTNPTFGDERRSVEAFILDQEADLYGHHVMVEFVGHLRDMVKFNGVDELLDAMARDVT
NARDILAKDKLLLDADTQPSA
>Mature_341_residues
MDIWSGLDSVPADLQGSVVTIGVFDGLHRGHQSLIGEAKKQAEELGVPCVMVTFDPHPIAVFLPGKEPTRLAPLDYRLNL
AAECGVDAALVIDFTKELAGLSAEEYFTTMIVDTLHARSVVVGENFTFGVNGAGTESTMRELGQKFGVNVTIAPLLHDDD
QRICSTLVRDYLDQGEVERANWALGRRYAVRGEVVRGAGRGGKELGYPTANLYLPTSVALPADGVYAGWFTITDDREIDK
EISRDIDGTMVPGVRYQTAISVGTNPTFGDERRSVEAFILDQEADLYGHHVMVEFVGHLRDMVKFNGVDELLDAMARDVT
NARDILAKDKLLLDADTQPSA

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=143, Percent_Identity=32.8671328671329, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786208, Length=331, Percent_Identity=31.7220543806647, Blast_Score=172, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17541882, Length=140, Percent_Identity=37.1428571428571, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644927, Length=139, Percent_Identity=33.8129496402878, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 37169; Mature: 37169

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIWSGLDSVPADLQGSVVTIGVFDGLHRGHQSLIGEAKKQAEELGVPCVMVTFDPHPIA
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEE
VFLPGKEPTRLAPLDYRLNLAAECGVDAALVIDFTKELAGLSAEEYFTTMIVDTLHARSV
EEECCCCCCEECCCCEEEEEHHHCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHCEE
VVGENFTFGVNGAGTESTMRELGQKFGVNVTIAPLLHDDDQRICSTLVRDYLDQGEVERA
EECCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCHH
NWALGRRYAVRGEVVRGAGRGGKELGYPTANLYLPTSVALPADGVYAGWFTITDDREIDK
HHHHCCEEEECCCEEECCCCCCCCCCCCCCEEEECCEECCCCCCEEEEEEEEECCHHHHH
EISRDIDGTMVPGVRYQTAISVGTNPTFGDERRSVEAFILDQEADLYGHHVMVEFVGHLR
HHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
DMVKFNGVDELLDAMARDVTNARDILAKDKLLLDADTQPSA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC
>Mature Secondary Structure
MDIWSGLDSVPADLQGSVVTIGVFDGLHRGHQSLIGEAKKQAEELGVPCVMVTFDPHPIA
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEE
VFLPGKEPTRLAPLDYRLNLAAECGVDAALVIDFTKELAGLSAEEYFTTMIVDTLHARSV
EEECCCCCCEECCCCEEEEEHHHCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHCEE
VVGENFTFGVNGAGTESTMRELGQKFGVNVTIAPLLHDDDQRICSTLVRDYLDQGEVERA
EECCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCHH
NWALGRRYAVRGEVVRGAGRGGKELGYPTANLYLPTSVALPADGVYAGWFTITDDREIDK
HHHHCCEEEECCCEEECCCCCCCCCCCCCCEEEECCEECCCCCCEEEEEEEEECCHHHHH
EISRDIDGTMVPGVRYQTAISVGTNPTFGDERRSVEAFILDQEADLYGHHVMVEFVGHLR
HHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
DMVKFNGVDELLDAMARDVTNARDILAKDKLLLDADTQPSA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]