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The map label for this gene is ppiB [H]

Identifier: 145295770

GI number: 145295770

Start: 1888542

End: 1889384

Strand: Direct

Name: ppiB [H]

Synonym: cgR_1696

Alternate gene names: 145295770

Gene position: 1888542-1889384 (Clockwise)

Preceding gene: 145295766

Following gene: 145295771

Centisome position: 56.98

GC content: 58.01

Gene sequence:

>843_bases
GTGAGTACTAATAAGGAACGACGCCAACAGGCGCTTTCCCAGCTGGAGAAAGAAATCAAAAGCCGGGACCGCAAAGAAAA
GACCAAGCCACTAACCGTGGTCTTTGCTTCCCTGGCTGTAATCCTGGTTGTCGTTGGCGGTATCTGGTACGCAGCTACCC
GCAGCACCGAAGACGAAGTCATCACCGCTGATGAAACATCCACCACCGCAGAGACCCCTGACTACCAGCCACTGGCGCTG
ACCCGCACCACTGCGCTCGGCGACTCCGTGACCTGTGAGTACCCAGATGCTGGCGAGGCTTCCAAGGATGTCTCCAAGCC
TGCTACTGAAAACGTGCCAGCAACCGGCACCGTGACCGTCAACCTGACCACTGCACAGGGCAACATCGGCATGGAACTTG
ATCGCTCCGTATCCCCTTGTACTGTCAACGCTGTTGAGCACATGGCTTCCGAGGGCTACTACAACGACACTGTCTGCCAC
CGCATCACCACCTCTGGCATTTACGTTCTGCAGTGCGGCGATCCAAGCGGCACTGGCGCAGGCGGCCCAGGGTTCAGCTT
CGCCAACGAATACCCAACCGACGAAGCAACTGACCTGACCACCCCAGTCATCTACGAGCGCGGCACCATCGCCATGGCTA
ACGCTGGCGCGGACACCAACGGTTCCCAGTTCTTCCTCAACTACGAGGACTCCCCACTGGCACCGAACTACACCTACTTC
GGCCAGATCACCGAAGAAGGACTTGCAACCCTAGATGCCATCGCAGAAGTTGGCGCTGAAGGTGGAACCGGCGACGGAGC
ACCAGCGCAAGAGGTTCGCATTGAATCCGCAACTGTTGCGTAA

Upstream 100 bases:

>100_bases
TCCCCCATCATTCCCTCAAGGTGTGAAGATACGGTTAGGATAGAAAAGAATTTTTTGACGTTGGACATTCTCAAAATCAA
GTAGCAAGGGATCAAACTCT

Downstream 100 bases:

>100_bases
GTTCTAAGCCCCTCTTCTTTCAACACCGTGTTTCTTGGCCAGCTGCCAAGAGGCACGGTGTTTTTGCTGTCTTTGACTAC
TATTTCTGCCGCTGGATCAC

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase B; Rotamase B [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSTNKERRQQALSQLEKEIKSRDRKEKTKPLTVVFASLAVILVVVGGIWYAATRSTEDEVITADETSTTAETPDYQPLAL
TRTTALGDSVTCEYPDAGEASKDVSKPATENVPATGTVTVNLTTAQGNIGMELDRSVSPCTVNAVEHMASEGYYNDTVCH
RITTSGIYVLQCGDPSGTGAGGPGFSFANEYPTDEATDLTTPVIYERGTIAMANAGADTNGSQFFLNYEDSPLAPNYTYF
GQITEEGLATLDAIAEVGAEGGTGDGAPAQEVRIESATVA

Sequences:

>Translated_280_residues
MSTNKERRQQALSQLEKEIKSRDRKEKTKPLTVVFASLAVILVVVGGIWYAATRSTEDEVITADETSTTAETPDYQPLAL
TRTTALGDSVTCEYPDAGEASKDVSKPATENVPATGTVTVNLTTAQGNIGMELDRSVSPCTVNAVEHMASEGYYNDTVCH
RITTSGIYVLQCGDPSGTGAGGPGFSFANEYPTDEATDLTTPVIYERGTIAMANAGADTNGSQFFLNYEDSPLAPNYTYF
GQITEEGLATLDAIAEVGAEGGTGDGAPAQEVRIESATVA
>Mature_279_residues
STNKERRQQALSQLEKEIKSRDRKEKTKPLTVVFASLAVILVVVGGIWYAATRSTEDEVITADETSTTAETPDYQPLALT
RTTALGDSVTCEYPDAGEASKDVSKPATENVPATGTVTVNLTTAQGNIGMELDRSVSPCTVNAVEHMASEGYYNDTVCHR
ITTSGIYVLQCGDPSGTGAGGPGFSFANEYPTDEATDLTTPVIYERGTIAMANAGADTNGSQFFLNYEDSPLAPNYTYFG
QITEEGLATLDAIAEVGAEGGTGDGAPAQEVRIESATVA

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=166, Percent_Identity=33.7349397590361, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI64276486, Length=171, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24308049, Length=194, Percent_Identity=31.4432989690722, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7706339, Length=164, Percent_Identity=35.3658536585366, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71997782, Length=157, Percent_Identity=36.3057324840764, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17539496, Length=167, Percent_Identity=35.9281437125749, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17532641, Length=167, Percent_Identity=35.3293413173653, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71980594, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71980590, Length=147, Percent_Identity=31.2925170068027, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922376, Length=174, Percent_Identity=32.7586206896552, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17986117, Length=166, Percent_Identity=32.5301204819277, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357249, Length=137, Percent_Identity=35.7664233576642, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29548; Mature: 29416

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNKERRQQALSQLEKEIKSRDRKEKTKPLTVVFASLAVILVVVGGIWYAATRSTEDEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCE
ITADETSTTAETPDYQPLALTRTTALGDSVTCEYPDAGEASKDVSKPATENVPATGTVTV
EECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHCCCCCCCCCCCEEEEE
NLTTAQGNIGMELDRSVSPCTVNAVEHMASEGYYNDTVCHRITTSGIYVLQCGDPSGTGA
EEEEECCCCCEEECCCCCCEEHHHHHHHHHCCCCCCHHHHEEECCCEEEEEECCCCCCCC
GGPGFSFANEYPTDEATDLTTPVIYERGTIAMANAGADTNGSQFFLNYEDSPLAPNYTYF
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEE
GQITEEGLATLDAIAEVGAEGGTGDGAPAQEVRIESATVA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCC
>Mature Secondary Structure 
STNKERRQQALSQLEKEIKSRDRKEKTKPLTVVFASLAVILVVVGGIWYAATRSTEDEV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCE
ITADETSTTAETPDYQPLALTRTTALGDSVTCEYPDAGEASKDVSKPATENVPATGTVTV
EECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHCCCCCCCCCCCEEEEE
NLTTAQGNIGMELDRSVSPCTVNAVEHMASEGYYNDTVCHRITTSGIYVLQCGDPSGTGA
EEEEECCCCCEEECCCCCCEEHHHHHHHHHCCCCCCHHHHEEECCCEEEEEECCCCCCCC
GGPGFSFANEYPTDEATDLTTPVIYERGTIAMANAGADTNGSQFFLNYEDSPLAPNYTYF
CCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEE
GQITEEGLATLDAIAEVGAEGGTGDGAPAQEVRIESATVA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]