Click here to switch to the map view.

The map label for this gene is pip [H]

Identifier: 145294761

GI number: 145294761

Start: 770333

End: 771616

Strand: Direct

Name: pip [H]

Synonym: cgR_0709

Alternate gene names: 145294761

Gene position: 770333-771616 (Clockwise)

Preceding gene: 145294760

Following gene: 145294762

Centisome position: 23.24

GC content: 54.91

Gene sequence:

>1284_bases
GTGGTTGGGGTGGTGTCCACCCCTGCGCGTAACCTGGGAAGCATGACTAAAACACTTGGTTCCCTTCAGCTGGAAGAAAT
CACGCTGACCCTCCCTCTGACTGAAGATGTGGCCGATGAACGCACCATTGATGTGTTCGCACGCATTGCCACACGCGTCG
GTGGGGAAGACCTTCCGTATTTAGTATTCCTGCAGGGTGGGCCTGGCAATGAAGCTCCACGTCCAAGCCTTAATCCCCTC
AACCCCAATTGGTTGGGCGTGGCCTTGGAGGAATACCGCGTGGTCATGTTGGATCAACGTGGCACCGGCCGTTCCACCCC
AGTGGGTAATGATATTTTGGAAAAACCCACAGCAGAAGTAGTGGAGTACTTATCCCACCTGCGCGCAGATGGCATTGTGC
GAGATGCTGAAGCCCTGCGTAAGCATTTGGGTGTGAATCAGTGGAACCTTTTAGGCCAGTCCTTCGGAGGTTTCACCACC
CTGCATTACTTGTCCCGGCACGCCGATTCCTTGGACAACGTGTTTATTACCGGCGGTCTCAGCGCTATTGATCGCCCAGC
AGAAGACGTGTATGCCAACTGTTACAACCGCATGCGCCGAAACTCTGAGGAATTCTACGGCCGCTTCCCGCAATTACGGG
AAACTTTCCGAGGGTTGGTTAATCGTGCTCGCGCCGGGGAGATTGTGCTTCCCACCGGCGAAGTTGTGTCAGAAACCCGG
CTGCGATCCCTTGGTCACTTGTTGGGTAGCAATGACGGCTGGTTTGATCTGTACAACCTGCTGGAATTAGATCCCACCTC
CAACGCTTTTGTCCATGACCTGGCAGGACTTTTGCCTTTCGGCAACCGCAACCCAATTTATTACGTGCTCCATGAGTCCT
CTTACGCCGACGGTGTGGTGACAAATTGGGCAGCAGAGCGTGTGCTTCCAGAGGATTTCCGCGAGGATCCAACACTGCTC
ACCGGTGAGCACGTGTTCCAGGAGTGGACAGACACCGTGCCTTCGCTCAAGCCATGGAAGGACGTTGCCCTGGCATTGGC
TCAGCAGGAATGGCCCAAGCTTTATGATGCGAAGGCATTGGAAAACTCACAGGCCACGGGTGCTGCAGCAGTGTATGCCA
ATGACGTTTTCGTGCCCGTGGATTACTCCTTAGAAACCGCACAGCACCTGCCCGGTGTGCAGCTGTTTATCACCAGCCAG
CATGAACACAATGGACTTCGTGCCAGCTCAGGTGCCGTACTCAAGCACCTTTTCGATCTCACACATGGCCGAGAGGTACG
CTGA

Upstream 100 bases:

>100_bases
TGCTAACAGGGGATATGCCACTGTGTACCCCACGGCGATGATCGGTAAAATCCTCGGCGCGCAGATATTGTTCTTGCTGC
TCTAAGGTGATTTTTGGGCA

Downstream 100 bases:

>100_bases
TTCCTCGTGTTAGTACTAGCCCTAGACACCTCAACCCCTGACCTGATCGTCGGCGTGGTCGACTCCGACACCGGAAACAC
CCGCGCCGAAACCATCATCG

Product: hypothetical protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MVGVVSTPARNLGSMTKTLGSLQLEEITLTLPLTEDVADERTIDVFARIATRVGGEDLPYLVFLQGGPGNEAPRPSLNPL
NPNWLGVALEEYRVVMLDQRGTGRSTPVGNDILEKPTAEVVEYLSHLRADGIVRDAEALRKHLGVNQWNLLGQSFGGFTT
LHYLSRHADSLDNVFITGGLSAIDRPAEDVYANCYNRMRRNSEEFYGRFPQLRETFRGLVNRARAGEIVLPTGEVVSETR
LRSLGHLLGSNDGWFDLYNLLELDPTSNAFVHDLAGLLPFGNRNPIYYVLHESSYADGVVTNWAAERVLPEDFREDPTLL
TGEHVFQEWTDTVPSLKPWKDVALALAQQEWPKLYDAKALENSQATGAAAVYANDVFVPVDYSLETAQHLPGVQLFITSQ
HEHNGLRASSGAVLKHLFDLTHGREVR

Sequences:

>Translated_427_residues
MVGVVSTPARNLGSMTKTLGSLQLEEITLTLPLTEDVADERTIDVFARIATRVGGEDLPYLVFLQGGPGNEAPRPSLNPL
NPNWLGVALEEYRVVMLDQRGTGRSTPVGNDILEKPTAEVVEYLSHLRADGIVRDAEALRKHLGVNQWNLLGQSFGGFTT
LHYLSRHADSLDNVFITGGLSAIDRPAEDVYANCYNRMRRNSEEFYGRFPQLRETFRGLVNRARAGEIVLPTGEVVSETR
LRSLGHLLGSNDGWFDLYNLLELDPTSNAFVHDLAGLLPFGNRNPIYYVLHESSYADGVVTNWAAERVLPEDFREDPTLL
TGEHVFQEWTDTVPSLKPWKDVALALAQQEWPKLYDAKALENSQATGAAAVYANDVFVPVDYSLETAQHLPGVQLFITSQ
HEHNGLRASSGAVLKHLFDLTHGREVR
>Mature_427_residues
MVGVVSTPARNLGSMTKTLGSLQLEEITLTLPLTEDVADERTIDVFARIATRVGGEDLPYLVFLQGGPGNEAPRPSLNPL
NPNWLGVALEEYRVVMLDQRGTGRSTPVGNDILEKPTAEVVEYLSHLRADGIVRDAEALRKHLGVNQWNLLGQSFGGFTT
LHYLSRHADSLDNVFITGGLSAIDRPAEDVYANCYNRMRRNSEEFYGRFPQLRETFRGLVNRARAGEIVLPTGEVVSETR
LRSLGHLLGSNDGWFDLYNLLELDPTSNAFVHDLAGLLPFGNRNPIYYVLHESSYADGVVTNWAAERVLPEDFREDPTLL
TGEHVFQEWTDTVPSLKPWKDVALALAQQEWPKLYDAKALENSQATGAAAVYANDVFVPVDYSLETAQHLPGVQLFITSQ
HEHNGLRASSGAVLKHLFDLTHGREVR

Specific function: Higher activity toward long peptides. Acts on hydroxyproline beta-naphthylamide with almost as high an activity as on proline beta-naphthylamide [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 47400; Mature: 47400

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGVVSTPARNLGSMTKTLGSLQLEEITLTLPLTEDVADERTIDVFARIATRVGGEDLPY
CCCCCCCCHHHHHHHHHHHHCEEEEEEEEEEECCHHHCCHHHHHHHHHHHHHCCCCCCCE
LVFLQGGPGNEAPRPSLNPLNPNWLGVALEEYRVVMLDQRGTGRSTPVGNDILEKPTAEV
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEHEEEEEEECCCCCCCCCCCCHHHCCCHHHH
VEYLSHLRADGIVRDAEALRKHLGVNQWNLLGQSFGGFTTLHYLSRHADSLDNVFITGGL
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCH
SAIDRPAEDVYANCYNRMRRNSEEFYGRFPQLRETFRGLVNRARAGEIVLPTGEVVSETR
HHHCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
LRSLGHLLGSNDGWFDLYNLLELDPTSNAFVHDLAGLLPFGNRNPIYYVLHESSYADGVV
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHH
TNWAAERVLPEDFREDPTLLTGEHVFQEWTDTVPSLKPWKDVALALAQQEWPKLYDAKAL
HHHHHHHCCCHHHCCCCCEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ENSQATGAAAVYANDVFVPVDYSLETAQHLPGVQLFITSQHEHNGLRASSGAVLKHLFDL
CCCCCCCEEEEEECCEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
THGREVR
CCCCCCC
>Mature Secondary Structure
MVGVVSTPARNLGSMTKTLGSLQLEEITLTLPLTEDVADERTIDVFARIATRVGGEDLPY
CCCCCCCCHHHHHHHHHHHHCEEEEEEEEEEECCHHHCCHHHHHHHHHHHHHCCCCCCCE
LVFLQGGPGNEAPRPSLNPLNPNWLGVALEEYRVVMLDQRGTGRSTPVGNDILEKPTAEV
EEEEECCCCCCCCCCCCCCCCCCCEEEEEEHEEEEEEECCCCCCCCCCCCHHHCCCHHHH
VEYLSHLRADGIVRDAEALRKHLGVNQWNLLGQSFGGFTTLHYLSRHADSLDNVFITGGL
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCH
SAIDRPAEDVYANCYNRMRRNSEEFYGRFPQLRETFRGLVNRARAGEIVLPTGEVVSETR
HHHCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHH
LRSLGHLLGSNDGWFDLYNLLELDPTSNAFVHDLAGLLPFGNRNPIYYVLHESSYADGVV
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHH
TNWAAERVLPEDFREDPTLLTGEHVFQEWTDTVPSLKPWKDVALALAQQEWPKLYDAKAL
HHHHHHHCCCHHHCCCCCEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ENSQATGAAAVYANDVFVPVDYSLETAQHLPGVQLFITSQHEHNGLRASSGAVLKHLFDL
CCCCCCCEEEEEECCEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
THGREVR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883756 [H]