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The map label for this gene is glmM

Identifier: 145294753

GI number: 145294753

Start: 761979

End: 763322

Strand: Direct

Name: glmM

Synonym: cgR_0701

Alternate gene names: 145294753

Gene position: 761979-763322 (Clockwise)

Preceding gene: 145294752

Following gene: 145294754

Centisome position: 22.99

GC content: 54.54

Gene sequence:

>1344_bases
ATGACTCGACTTTTTGGAACTGATGGCGTCCGCGGACTAGCCAATGAAGTACTCACCGCACCTTTGGCCCTGAAACTGGG
TGCCGCTGCAGCTCACGTACTTACCGCAGAGAAACGCGTAGATGGACGCCGCCCGGTTGCGATCGTTGGTCGGGATCCTC
GAGTCTCTGGAGAGATGCTCGCGGCAGCACTTTCAGCAGGCATGGCCAGCCAGGGTGTTGATGTCATTCGTGTTGGTGTC
ATCCCAACCCCAGCTGTTGCATTCCTCACCGATGATTATGGCGCTGATATGGGCGTGATGATTTCTGCATCCCACAACCC
AATGCCGGACAACGGAATCAAGTTCTTCTCCGCAGGTGGACACAAGCTTCCAGACCATGTGGAAGACGAGATTGAGCGTG
TCATGGACAGCTTGCCTGCCGAAGGCCCAACCGGGCATGGAGTTGGCCGTGTCATTGAAGAAGCAACCGATGCACAAGAC
CGCTACCTGGAGCACCTGAAGGAAGCTGTTCCTACGTCACTTGAAGGCATCAAGATTGTTGTGGATGCAGCCAATGGTGC
AGCAAGCGTTGTAGCTCCAAAGGCTTATGAAGCAGCAGGTGCAACTGTAATTGCTATTCATAACAAGCCAGACTCCTACA
ACATCAACATGGATTGCGGTTCCACCCACATTGATCAGGTGCAGGCGGCAGTTCTGAAGCACGGTGCTGACCTTGGACTC
GCACACGACGGCGATGCTGACCGTTGTTTGGCTGTGGACAAAGATGGAAACCTCATTGACGGTGATCAGATCATGGCAAT
GTTAGCCATTGCGATGAAAGAAAACGGCGAGCTGCGCAAGAACACCCTCGTGGGCACCGTCATGAGCAACTTGGGACTGA
AGATTGCCATGGATGAAGCCGGAATTACGCTGCGAACCACCAAGGTGGGCGACCGCTACGTGCTGGAAGACCTCAATGCG
GGTGGATTCAGCCTTGGTGGCGAGCAGTCTGGACACATTGTTCTTCCAGATCACGGCACCACTGGCGATGGAACTTTGAC
TGGTCTTTCCATCATGGCGCGCATGGCTGAAACCGGAAAATCCTTGGGCGAGTTGGCACAAGCGATGACGGTTCTGCCAC
AGGTTCTGATCAATGTGCCAGTTTCTGATAAATCCACTATCGTTTCTCACCCAAGTGTCGTTGCAGCAATCGCTGAAGCT
GAAGCGGAGTTGGGTTCTACCGGTCGCGTGCTTCTTCGCGCTTCTGGCACCGAGGAGCTTTTCCGTGTGATGGTCGAAGC
TGGCGATAAGGAACAAGCCCGCCGCATTGCGGGACGTCTTTCTGCCGTGGTCGCGGAAGTCTAA

Upstream 100 bases:

>100_bases
CTTGGATTTTCACTTGGGTTTGCACAGTTCAACCCAATAAAAATTGTTGAACAGGGTTTTGAACAATGTGTTCTCAGCTT
GGCAGTGCATAATTAATCGC

Downstream 100 bases:

>100_bases
TTCACTTCCGTTACAGCGTAACGCGATCTGCGAGGTCGAATCCGCCCAAAGGCTACTTATATCGAATTGGGCAGGTTTGA
CGCTTGAGGGGCCACATAAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTRLFGTDGVRGLANEVLTAPLALKLGAAAAHVLTAEKRVDGRRPVAIVGRDPRVSGEMLAAALSAGMASQGVDVIRVGV
IPTPAVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGGHKLPDHVEDEIERVMDSLPAEGPTGHGVGRVIEEATDAQD
RYLEHLKEAVPTSLEGIKIVVDAANGAASVVAPKAYEAAGATVIAIHNKPDSYNINMDCGSTHIDQVQAAVLKHGADLGL
AHDGDADRCLAVDKDGNLIDGDQIMAMLAIAMKENGELRKNTLVGTVMSNLGLKIAMDEAGITLRTTKVGDRYVLEDLNA
GGFSLGGEQSGHIVLPDHGTTGDGTLTGLSIMARMAETGKSLGELAQAMTVLPQVLINVPVSDKSTIVSHPSVVAAIAEA
EAELGSTGRVLLRASGTEELFRVMVEAGDKEQARRIAGRLSAVVAEV

Sequences:

>Translated_447_residues
MTRLFGTDGVRGLANEVLTAPLALKLGAAAAHVLTAEKRVDGRRPVAIVGRDPRVSGEMLAAALSAGMASQGVDVIRVGV
IPTPAVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGGHKLPDHVEDEIERVMDSLPAEGPTGHGVGRVIEEATDAQD
RYLEHLKEAVPTSLEGIKIVVDAANGAASVVAPKAYEAAGATVIAIHNKPDSYNINMDCGSTHIDQVQAAVLKHGADLGL
AHDGDADRCLAVDKDGNLIDGDQIMAMLAIAMKENGELRKNTLVGTVMSNLGLKIAMDEAGITLRTTKVGDRYVLEDLNA
GGFSLGGEQSGHIVLPDHGTTGDGTLTGLSIMARMAETGKSLGELAQAMTVLPQVLINVPVSDKSTIVSHPSVVAAIAEA
EAELGSTGRVLLRASGTEELFRVMVEAGDKEQARRIAGRLSAVVAEV
>Mature_446_residues
TRLFGTDGVRGLANEVLTAPLALKLGAAAAHVLTAEKRVDGRRPVAIVGRDPRVSGEMLAAALSAGMASQGVDVIRVGVI
PTPAVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGGHKLPDHVEDEIERVMDSLPAEGPTGHGVGRVIEEATDAQDR
YLEHLKEAVPTSLEGIKIVVDAANGAASVVAPKAYEAAGATVIAIHNKPDSYNINMDCGSTHIDQVQAAVLKHGADLGLA
HDGDADRCLAVDKDGNLIDGDQIMAMLAIAMKENGELRKNTLVGTVMSNLGLKIAMDEAGITLRTTKVGDRYVLEDLNAG
GFSLGGEQSGHIVLPDHGTTGDGTLTGLSIMARMAETGKSLGELAQAMTVLPQVLINVPVSDKSTIVSHPSVVAAIAEAE
AELGSTGRVLLRASGTEELFRVMVEAGDKEQARRIAGRLSAVVAEV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=452, Percent_Identity=46.6814159292035, Blast_Score=341, Evalue=6e-95,
Organism=Escherichia coli, GI1788361, Length=461, Percent_Identity=29.5010845986985, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786904, Length=401, Percent_Identity=26.1845386533666, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_CORGB (A4QBS5)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137574.1
- ProteinModelPortal:   A4QBS5
- SMR:   A4QBS5
- STRING:   A4QBS5
- GeneID:   4993873
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0701
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14318
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 46446; Mature: 46314

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLFGTDGVRGLANEVLTAPLALKLGAAAAHVLTAEKRVDGRRPVAIVGRDPRVSGEML
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
AAALSAGMASQGVDVIRVGVIPTPAVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGG
HHHHHHCHHHCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCEEEECCC
HKLPDHVEDEIERVMDSLPAEGPTGHGVGRVIEEATDAQDRYLEHLKEAVPTSLEGIKIV
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEE
VDAANGAASVVAPKAYEAAGATVIAIHNKPDSYNINMDCGSTHIDQVQAAVLKHGADLGL
EECCCCCCEEECCCCHHCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCC
AHDGDADRCLAVDKDGNLIDGDQIMAMLAIAMKENGELRKNTLVGTVMSNLGLKIAMDEA
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECC
GITLRTTKVGDRYVLEDLNAGGFSLGGEQSGHIVLPDHGTTGDGTLTGLSIMARMAETGK
CEEEEEECCCCCHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SLGELAQAMTVLPQVLINVPVSDKSTIVSHPSVVAAIAEAEAELGSTGRVLLRASGTEEL
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCHHHH
FRVMVEAGDKEQARRIAGRLSAVVAEV
HHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRLFGTDGVRGLANEVLTAPLALKLGAAAAHVLTAEKRVDGRRPVAIVGRDPRVSGEML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
AAALSAGMASQGVDVIRVGVIPTPAVAFLTDDYGADMGVMISASHNPMPDNGIKFFSAGG
HHHHHHCHHHCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCEEEECCC
HKLPDHVEDEIERVMDSLPAEGPTGHGVGRVIEEATDAQDRYLEHLKEAVPTSLEGIKIV
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEE
VDAANGAASVVAPKAYEAAGATVIAIHNKPDSYNINMDCGSTHIDQVQAAVLKHGADLGL
EECCCCCCEEECCCCHHCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCC
AHDGDADRCLAVDKDGNLIDGDQIMAMLAIAMKENGELRKNTLVGTVMSNLGLKIAMDEA
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECC
GITLRTTKVGDRYVLEDLNAGGFSLGGEQSGHIVLPDHGTTGDGTLTGLSIMARMAETGK
CEEEEEECCCCCHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SLGELAQAMTVLPQVLINVPVSDKSTIVSHPSVVAAIAEAEAELGSTGRVLLRASGTEEL
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCHHHH
FRVMVEAGDKEQARRIAGRLSAVVAEV
HHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA