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The map label for this gene is ugd [H]

Identifier: 145294725

GI number: 145294725

Start: 730768

End: 731934

Strand: Direct

Name: ugd [H]

Synonym: cgR_0673

Alternate gene names: 145294725

Gene position: 730768-731934 (Clockwise)

Preceding gene: 145294724

Following gene: 145294726

Centisome position: 22.05

GC content: 47.22

Gene sequence:

>1167_bases
ATGAAAATCGCTGTTGCTGGCCTTGGCTTTGTCGGAACTTCAAATGCGGCTTTGCTCTCGAAGAACAACGAAGTCATCGC
AATGGACATCAACCAAACACGCGTAGATGCCCTGAACAACTATGTGTCTCCAGTAGAAGACGCAGAGCTAGATAGATATC
TAGCAACCAAGCCTGAAACATTACGTGCAACCACAGATACCCAAGAGGCTTATGGGGACGCAGAATTCGTCATTGTTGCG
ACACCCACTGACTATGATCCCGAAACCAATTTCTTTGACACCAAATACGTGGAAAGTGCCATTTCTGAGGCACAAAGGGT
AAATCCTGATGCGAGTATCGTTATTAAATCAACGATTCCTGTCGGTTTTACAGAAAAAATGCGCGCACAGTATCCCAATG
CCACCATCTTCCCATCGCCAGAGTTCCTGAGAGAAGGCAGTGCTTTTTACGACAACCTGCATCCCTCGCGCATCGTCGTT
GGGGAGCGCTCAGAGGTGGGACAACAATTTGCTCTGCTTCTCAAGGAAGGCGCAGTGGATGAGGCCACACCAGTCCTTTT
CACTGATGCCACAGAAGCAGAAGCGATCAAGTTGTTCGCCAACACTTATCTGGCGATGCGTGTGTCTTACTTCAATGAGC
TGGATACTTATGCGTCCACCATGGGTTTAAAGTCCAAGCAAATTATTGAGGGCGTTAGCCTCGACCCTCGCATCGGCAAC
AAATACAACAACCCGTCTTTTGGCTATGGCGGTTACTGTTTGCCCAAGGACACAAAGCAGCTATTGGCCAATTTCGATAC
TGTTCCGCAGAGGATGATTTCGGCGATTGTTGAGTCCAATTCGGTTCGTAAAGACTTCATCGCTGAAGATATCTTGAGTC
GACAACCCAAAACTGTGGGTGTGTATCGCCTTGTCATGAAAACTGGATCAGACAATTTTAGATCTTCTTCAGTTCAAGGG
GTCATAAAAAGGATCCAACAAGCAGGTGTTCCTGTGGTTATTTATGAACCCACTTTGAACTCAGAAAGCTACTTTGATTC
CAAGGTTGTCACAGACCTCGATGAGTTCAAGCGTGACTGCGACCTGATTATTGCCAACAGGCCAACCCATGAGCTCGACG
ATATTGCCGATCGCATCTATACGCGGGATCTCTTCGAACGTGATTAA

Upstream 100 bases:

>100_bases
ACATAAAAGCTGTTTTAGTAGTTTACTTCTGATTGTTTGTCGTTTACGTAGACGTTTTCTCCATGCCTAATCCGGTTTAA
AAATGAGAGAGCAGGTAATC

Downstream 100 bases:

>100_bases
TTAGTAGGTATGGGAATCATACATATCGGGCCGAGTCCTCAGCTTTTGCCAGTTAAGCTCGGCCCGGGCGATATTTTAGA
GATCGATAGCGACCTCACCG

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAVAGLGFVGTSNAALLSKNNEVIAMDINQTRVDALNNYVSPVEDAELDRYLATKPETLRATTDTQEAYGDAEFVIVA
TPTDYDPETNFFDTKYVESAISEAQRVNPDASIVIKSTIPVGFTEKMRAQYPNATIFPSPEFLREGSAFYDNLHPSRIVV
GERSEVGQQFALLLKEGAVDEATPVLFTDATEAEAIKLFANTYLAMRVSYFNELDTYASTMGLKSKQIIEGVSLDPRIGN
KYNNPSFGYGGYCLPKDTKQLLANFDTVPQRMISAIVESNSVRKDFIAEDILSRQPKTVGVYRLVMKTGSDNFRSSSVQG
VIKRIQQAGVPVVIYEPTLNSESYFDSKVVTDLDEFKRDCDLIIANRPTHELDDIADRIYTRDLFERD

Sequences:

>Translated_388_residues
MKIAVAGLGFVGTSNAALLSKNNEVIAMDINQTRVDALNNYVSPVEDAELDRYLATKPETLRATTDTQEAYGDAEFVIVA
TPTDYDPETNFFDTKYVESAISEAQRVNPDASIVIKSTIPVGFTEKMRAQYPNATIFPSPEFLREGSAFYDNLHPSRIVV
GERSEVGQQFALLLKEGAVDEATPVLFTDATEAEAIKLFANTYLAMRVSYFNELDTYASTMGLKSKQIIEGVSLDPRIGN
KYNNPSFGYGGYCLPKDTKQLLANFDTVPQRMISAIVESNSVRKDFIAEDILSRQPKTVGVYRLVMKTGSDNFRSSSVQG
VIKRIQQAGVPVVIYEPTLNSESYFDSKVVTDLDEFKRDCDLIIANRPTHELDDIADRIYTRDLFERD
>Mature_388_residues
MKIAVAGLGFVGTSNAALLSKNNEVIAMDINQTRVDALNNYVSPVEDAELDRYLATKPETLRATTDTQEAYGDAEFVIVA
TPTDYDPETNFFDTKYVESAISEAQRVNPDASIVIKSTIPVGFTEKMRAQYPNATIFPSPEFLREGSAFYDNLHPSRIVV
GERSEVGQQFALLLKEGAVDEATPVLFTDATEAEAIKLFANTYLAMRVSYFNELDTYASTMGLKSKQIIEGVSLDPRIGN
KYNNPSFGYGGYCLPKDTKQLLANFDTVPQRMISAIVESNSVRKDFIAEDILSRQPKTVGVYRLVMKTGSDNFRSSSVQG
VIKRIQQAGVPVVIYEPTLNSESYFDSKVVTDLDEFKRDCDLIIANRPTHELDDIADRIYTRDLFERD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=382, Percent_Identity=26.4397905759162, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI296040438, Length=281, Percent_Identity=26.6903914590747, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI296040443, Length=367, Percent_Identity=23.433242506812, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=61.340206185567, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI48994968, Length=366, Percent_Identity=27.8688524590164, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560350, Length=407, Percent_Identity=27.7641277641278, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136908, Length=375, Percent_Identity=28, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43216; Mature: 43216

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGLGFVGTSNAALLSKNNEVIAMDINQTRVDALNNYVSPVEDAELDRYLATKPET
CEEEEEECCEECCCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
LRATTDTQEAYGDAEFVIVATPTDYDPETNFFDTKYVESAISEAQRVNPDASIVIKSTIP
EEECCCHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
VGFTEKMRAQYPNATIFPSPEFLREGSAFYDNLHPSRIVVGERSEVGQQFALLLKEGAVD
CCCHHHHHHCCCCCEECCCHHHHHCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCC
EATPVLFTDATEAEAIKLFANTYLAMRVSYFNELDTYASTMGLKSKQIIEGVSLDPRIGN
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
KYNNPSFGYGGYCLPKDTKQLLANFDTVPQRMISAIVESNSVRKDFIAEDILSRQPKTVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
VYRLVMKTGSDNFRSSSVQGVIKRIQQAGVPVVIYEPTLNSESYFDSKVVTDLDEFKRDC
HEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHHHHHHCCC
DLIIANRPTHELDDIADRIYTRDLFERD
CEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAVAGLGFVGTSNAALLSKNNEVIAMDINQTRVDALNNYVSPVEDAELDRYLATKPET
CEEEEEECCEECCCCCEEEECCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
LRATTDTQEAYGDAEFVIVATPTDYDPETNFFDTKYVESAISEAQRVNPDASIVIKSTIP
EEECCCHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
VGFTEKMRAQYPNATIFPSPEFLREGSAFYDNLHPSRIVVGERSEVGQQFALLLKEGAVD
CCCHHHHHHCCCCCEECCCHHHHHCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCC
EATPVLFTDATEAEAIKLFANTYLAMRVSYFNELDTYASTMGLKSKQIIEGVSLDPRIGN
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
KYNNPSFGYGGYCLPKDTKQLLANFDTVPQRMISAIVESNSVRKDFIAEDILSRQPKTVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHH
VYRLVMKTGSDNFRSSSVQGVIKRIQQAGVPVVIYEPTLNSESYFDSKVVTDLDEFKRDC
HEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHHHHHHCCC
DLIIANRPTHELDDIADRIYTRDLFERD
CEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]